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Radiculopathies: Cervical & Lumbosacral - Complete Exam Guide
The Big Picture First
Radiculopathy = nerve root compression giving a triad:
- Pain radiating in a dermatomal pattern
- Sensory loss/paresthesias in the dermatome
- Motor weakness in the myotome + reflex loss
The key exam question is always: "Which level?" - answered by matching the pattern of weakness + sensory loss + reflex change.
PART 1: CERVICAL RADICULOPATHY
Anatomy Concept to Know First
The cervical nerve root exits above its numbered vertebra (C5 root exits between C4-C5). This means:
- C4-C5 disc herniation → compresses C5 root
- C5-C6 disc herniation → compresses C6 root
- C6-C7 disc herniation → compresses C7 root
- C7-T1 disc herniation → compresses C8 root
Mnemonic: "Cervical roots exit ABOVE = disc number = root below it"
C5, C6, C7 are the most commonly affected roots (levels of greatest cervical mobility and disc degeneration) - as confirmed in Bradley and Daroff's Neurology in Clinical Practice.
Cervical Radiculopathy at a Glance
The "5-6-7-8 Ladder" - Master Mnemonic for Cervical Roots
| Root | Pain/Sensory area | Key Muscle | Test movement | Reflex | Mnemonic |
|---|
| C5 | Shoulder/lateral arm | Deltoid, Biceps | Shoulder abduction | Biceps | "C5 = Shoulder shrug/abDuct" |
| C6 | Lateral forearm, thumb + index | Biceps, Brachioradialis, Wrist extensors | Elbow flexion + wrist extension | Brachioradialis | "C6 = siX-pack thumb (thumb is digit 1=index)" |
| C7 | Middle finger, posterior arm | Triceps, Wrist flexors, Pronators | Elbow extension | Triceps | "C7 = sEVEn = EXTEND (triceps)" |
| C8 | Ring + little finger, medial forearm | Finger flexors, Intrinsics | Grip strength / finger flexion | None | "C8 = grEIGHt (grip)" |
| T1 | Medial upper arm | Intrinsics (interossei) | Finger abduction/adduction | None | "T1 = Tiny interossei" |
Master Mnemonic: "BiBoTri-No" = C5 Biceps / C6 Brachioradialis / C7 Triceps / C8 No reflex
Or remember: B-B-T going down = Biceps (C5-C6), Brachioradialis (C6), Triceps (C7).
C5 Radiculopathy (C4-C5 disc)
History: Pain from neck → shoulder → lateral arm. Weakness lifting arm overhead.
Dermatome: Lateral shoulder, lateral upper arm ("epaulette" area)
Myotome weak: Deltoid (shoulder abduction), Biceps, Supraspinatus
Reflex lost: Biceps jerk (C5-C6)
Tip: Patient cannot comb their hair or lift arm above shoulder. "Shoulder problem, but no neck trauma."
Test: Resisted shoulder abduction - patient holds arm at 90° while you push down.
C6 Radiculopathy (C5-C6 disc) - Most common cervical level
History: Pain down lateral forearm into thumb + index finger. "My thumb goes numb."
Dermatome: Lateral forearm, thumb, index finger, lateral half of palm
Myotome weak: Biceps (elbow flexion), Brachioradialis, Wrist extensors (ECRL, ECRB)
Reflex lost: Biceps jerk AND Brachioradialis jerk
Special sign: "Inverted" or "paradoxical" brachioradialis reflex (tap BR → finger flexors contract but no BR contraction = myelopathy at same level)
Test: Resisted elbow flexion + resisted wrist extension
C7 Radiculopathy (C6-C7 disc) - Most common overall
History: Pain to middle finger (± ring finger). Weakness pushing things away ("can't do push-ups"). Subscapular/interscapular pain is classic.
Dermatome: Middle finger, dorsal forearm, posterior arm
Myotome weak: Triceps, Wrist flexors (FCR, FCU), Pronator teres, Finger extensors
Reflex lost: Triceps jerk (ONLY reflex exclusively for C7)
Tip: Triceps jerk = C7 exclusively. Test by tapping triceps tendon with elbow at 90°.
Test: Resisted elbow extension
C8 Radiculopathy (C7-T1 disc)
History: Pain/numbness to ring + little finger, medial forearm. Clumsy hand.
Dermatome: Medial forearm, ring + little finger
Myotome weak: Finger flexors (FDP, FDS), Intrinsic hand muscles, Abductor pollicis brevis
Reflex: No dedicated reflex (a common exam trap!)
Tip: C8 looks like ulnar nerve but SNAPS are normal in radiculopathy (preganglionic lesion)
T1 Radiculopathy
History: Medial upper arm pain/numbness, intrinsic hand weakness (often Pancoast tumor should be excluded)
Dermatome: Medial upper arm, inner elbow
Myotome: Intrinsic hand muscles (interossei, lumbricals)
Exam: Finger abduction/adduction weakness, look for Horner syndrome (ptosis, miosis, anhidrosis) - suggests Pancoast tumor
Special Provocation Tests for Cervical Radiculopathy
| Test | Technique | What positive means | Sens/Spec |
|---|
| Spurling Test | Extend neck + side-bend toward painful side + axial compression downward | Reproduces radicular arm pain | Low sensitivity, HIGH specificity |
| Cervical Distraction Test | Patient supine, lift head with hands under chin/occiput | Relief of radicular pain | Moderate sens, high spec |
| Upper Limb Tension Test (ULTT) | Scapular depression + shoulder abduction/flexion + elbow/wrist/finger extension, neck laterally bent away | Reproduces arm/hand pain | HIGH sensitivity (~90%), low specificity |
| Shoulder Abduction Relief Sign | Patient raises hand/arm above head | Relieves pain | Specific for C4-5 or C5-6 |
| Valsalva/Cough | Increases intrathecal pressure | Worsens radicular pain | ----- |
From Textbook of Family Medicine: Spurling test = low sens, high spec. Upper limb tension test = sensitivity >90%, low specificity. Straight-leg raise (lumbar) = sensitivity 91%, specificity 26%.
Mnemonic for Spurling: "SPECific for radiculopathy" = Spurling = SPECificity
PART 2: LUMBOSACRAL RADICULOPATHY
Key Anatomy Concept
In the lumbar region, roots exit below their numbered vertebra (unlike cervical). However, the disc at L4-L5 typically compresses the traversing L5 root (not L4), because L4 exits at L4-L5 foramen:
- L3-L4 disc → compresses L4 root (exiting at L3-L4 foramina) or traversing L4
- L4-L5 disc herniation → usually compresses traversing L5 root
- L5-S1 disc herniation → usually compresses traversing S1 root
Most common: S1 (from L5-S1 disc) and L5 (from L4-L5 disc)
Lumbosacral Radiculopathy Table
Body Dermatome Map
Lumbar Root Summary Table
| Root | Disc Level | Pain Pattern | Key Weakness | Reflex Lost | Sensory Area | Mnemonic |
|---|
| L2 | L1-L2 | Anterior thigh | Hip flexion | None | Anterior/medial upper thigh | "L2 = Loin to groin" |
| L3 | L2-L3 | Anterior thigh → medial knee | Knee extension, hip adduction | Patellar (partial) | Anterior thigh + medial knee | "L3 = Leg thREE, thigh/knee" |
| L4 | L3-L4 | Anterior thigh → medial shin | Knee extension (quads), foot inversion | Patellar/Knee jerk | Medial lower leg | "L4 = 4ward = kneecap" |
| L5 | L4-L5 | Buttock → lateral leg → dorsum foot → big toe | Foot/great toe dorsiflexion (EHL), hip abduction | Ankle jerk (sometimes, medial) | Lateral leg, dorsum foot, big toe | "L5 = L5ift foot up, big toe" |
| S1 | L5-S1 | Buttock → posterior thigh → lateral foot | Plantar flexion (calf), eversion | Ankle jerk / Achilles | Posterior thigh, calf, lateral foot/heel | "S1 = Soles of feet, Sole=S1, Ankle jerk" |
| S2-4 | - | Perineum, inner thighs | Bladder/bowel, sphincters | Bulbocavernosus/anal | Saddle area | "S2,3,4 keeps the poo off the floor" |
Lumbosacral Root Mnemonics
"2-3-4 in front, 5-1 behind"
- L2, L3, L4 radiculopathies → pain anteriorly (anterior thigh, medial leg) - tested by Femoral nerve stretch test
- L5, S1 → pain posteriorly (buttock, posterior leg) - tested by Straight Leg Raise (SLR)
Key Reflex Mnemonics
| Reflex | Root | Mnemonic |
|---|
| Biceps | C5-C6 | "B5-6 = Biceps 5 and 6" |
| Brachioradialis | C6 | "BR = Brachioradialis = Rad-6" |
| Triceps | C7 | "Tri7 = Triceps C7" |
| Patellar (knee jerk) | L3-L4 | "Patellar = L3-L4, knee goes fore" |
| Achilles (ankle jerk) | S1 | "Aching S1 ankle" or "S1 = Sole/Achilles" |
The "L4-L5-S1 Clinical Triad" (Exam Favourite)
| Feature | L4 | L5 | S1 |
|---|
| Weakness | Knee extension, foot inversion | Dorsiflexion of foot/big toe | Plantar flexion (stand on tiptoe) |
| Sensory | Medial shin | Dorsum foot, big toe | Lateral foot, heel |
| Reflex | Knee jerk ↓ | Ankle jerk (sometimes) or absent | Ankle jerk ↓ |
| Quick test | Walk on heels (tests L4/L5) | Cannot lift big toe | Cannot stand on tiptoes |
| Disc | L3-L4 | L4-L5 | L5-S1 |
Memory hook:
- L4 = "4wards walking" = knee extension, heel walking
- L5 = "L5ft the foot up" = dorsiflexion, extensor hallucis longus (EHL)
- S1 = "S1 = Sole" = plantar flexion, ankle jerk
Clinical Provocation Tests for Lumbosacral Radiculopathy
| Test | Technique | Roots tested | Sens/Spec |
|---|
| Straight Leg Raise (SLR / Lasègue) | Supine, passively raise straight leg. Positive: radicular pain at 30-70° (NOT just back pain) | L5, S1 | Sensitivity 91%, specificity 26% |
| Crossed SLR | Raising the contralateral leg reproduces ipsilateral radicular pain | L5, S1 | Low sensitivity, high specificity (~90%) |
| Femoral Nerve Stretch Test | Prone, flex knee to 90°, extend hip. Positive: anterior thigh pain | L2, L3, L4 | For upper lumbar roots |
| Slump Test | Seated, slump forward + extend knee + dorsiflex ankle. Positive: sciatic pain | L5, S1 | High sensitivity |
| Bowstring Sign | After positive SLR, flex knee slightly - if pain returns with popliteal fossa pressure, positive | L5, S1 | High specificity |
Key from Rheumatology textbook: Femoral stretch test = L2/L3/L4; SLR/Bowstring = L5/S1
Mnemonic: "SLR for LOW (L5-S1 = low lumbar), Femoral for HIGH (L2-3-4 = upper lumbar)"
PART 3: RED FLAGS (Cauda Equina - Must Not Miss!)
Cauda equina syndrome = massive central disc herniation (usually L4/5 or L5/S1) compressing multiple roots:
- Bilateral leg pain/weakness
- Saddle anesthesia (S2-4 dermatome - perineum, inner thighs)
- Bladder retention or incontinence (most reliable sign)
- Anal sphincter laxity (loss of anal tone)
- Decreased/absent bilateral ankle jerks
"Saddle + Bladder = Emergency Surgery" - From Bradley and Daroff's and Textbook of Family Medicine: sphincter disturbance from lumbar disease requires urgent surgical consideration.
Historical red flags for any back pain:
- Fever, weight loss (infection/malignancy)
- History of cancer
- Bowel/bladder dysfunction (CES)
- Saddle anesthesia
- Bilateral leg weakness
- Recent major trauma
- IV drug use / immunosuppression
PART 4: DIAGNOSTIC INVESTIGATIONS
| Test | Radiculopathy Finding | Notes |
|---|
| MRI spine | Disc herniation or osteophyte compressing root | Investigation of choice |
| CT myelography | Same as MRI; better for calcified lesions, post-op patients | If MRI contraindicated |
| NCS | Normal SNAPs (lesion is preganglionic, proximal to DRG) | Differentiates from peripheral neuropathy |
| EMG (needle) | Fibrillations/PSWs in myotome distribution + paraspinals | Confirms radiculopathy; paraspinals are key |
| F-waves | May be delayed in affected root | Less sensitive |
| H-reflex | Absent/asymmetric = S1 radiculopathy (sensitivity 50%, specificity 91%) | Very specific for S1 |
Key NCS point for exams: In radiculopathy, the dorsal root ganglion (DRG) is outside the spinal canal, so sensory axons peripheral to the DRG are intact → SNAPs normal despite sensory symptoms. CMAPs may be reduced if significant motor axon loss. This distinguishes radiculopathy from peripheral neuropathy/plexopathy.
"Normal SNAP = preganglionic = radiculopathy" - Bradley and Daroff's Neurology
PART 5: MASTER MEMORY TABLE
Upper Limb Reflexes - "BiBoTri No" Mnemonic
C5 = Biceps (and Brachioradialis shares)
C6 = Brachioradialis (and Biceps shares)
C7 = Triceps (exclusive)
C8 = Nothing (no reflex)
Lower Limb Reflexes
L3-L4 = Patellar (knee jerk) → "kneecap = L34"
S1 = Achilles (ankle jerk) → "sole/ankle = S1"
PART 6: DERMATOMAL KEY LANDMARKS (USMLE/MRCP Favourites)
| Landmark | Root |
|---|
| Nipple line | T4 |
| Xiphoid process | T7 |
| Umbilicus | T10 |
| Groin / inguinal ligament | L1 |
| Anterior thigh | L2-L3 |
| Medial shin/knee | L4 |
| Dorsum of foot / big toe | L5 |
| Lateral foot / heel / sole | S1 |
| Perineum / saddle area | S2-S4 |
Thoracic landmarks mnemonic: "T4 = Tits (nipples), T10 = TEN = Tummy button (umbilicus)"
PART 7: HISTORY TAKING - THE RADICULOPATHY TEMPLATE
A structured history for FCPS/MRCP/USMLE OSCEs:
- Character of pain: burning, shooting, lancinating (neuropathic quality)
- Radiation: Does it radiate beyond the knee (lumbar) or elbow (cervical)?
- Aggravating factors: Cough/sneeze/Valsalva worsens → increased intrathecal pressure → radiculopathy
- Relieving factors: Arm raised above head relieves cervical pain (shoulder abduction relief sign)
- Duration and onset: Acute (disc) vs. gradual (spondylosis/stenosis)
- Neurological symptoms: Numbness, tingling in which finger/toe?
- Weakness: Specific activities - can't open jars (C8/T1), can't comb hair (C5), can't walk on tiptoes (S1), dragging foot (L5)
- Red flags: Bilateral, bowel/bladder, saddle numbness
Quick Summary Card for Exams
Cervical
- C5: Shoulder abduction weak, Biceps reflex ↓, lateral arm numb
- C6: Elbow flex + wrist extend weak, Brachioradialis reflex ↓, thumb/index numb - most common
- C7: Elbow extend weak, Triceps reflex ↓, middle finger numb
- C8: Finger flex weak, NO reflex, ring/little finger numb
- Spurling = high spec, ULTT = high sens
Lumbosacral
- L4: Quad/knee extend weak, Knee jerk ↓, medial shin numb, heel walk
- L5: Foot/big toe dorsiflex weak (EHL), ankle jerk sometimes ↓, dorsum foot/big toe numb
- S1: Plantar flex weak (calf), Ankle jerk ↓, lateral foot numb, tiptoe test
- SLR tests L5/S1 (high sens), Femoral stretch tests L2/L3/L4 (high spec)
- Cauda equina = saddle anesthesia + bladder = EMERGENCY
Sources: Bradley and Daroff's Neurology in Clinical Practice (cervical radiculopathy chapters);
Textbook of Family Medicine 9e (spine physical examination tables); Lecturio medical illustrations; neurological examination evidence from
PMC scoping review on cervical radiculopathy.