How to diagnose different types of radiculopathies of the cervical and lumbosacral region from history, physical examination, and motor, sensory testing. How to remember which nerve root supplies which dermatome, myotome, and reflexes, and muscles ? Also give images and illustrations to remember them easily .. Give me mnemonics wherever possible and make this topic easy for me to remember for my first FCPS Part 2 exam, MRCP and USMLE steps exam.

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cervical lumbosacral radiculopathy dermatome myotome reflex mnemonic USMLE MRCP

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lumbar radiculopathy L3 L4 L5 S1 dermatome myotome reflex table diagram illustration

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Radiculopathies: Cervical & Lumbosacral - Complete Exam Guide

The Big Picture First

Radiculopathy = nerve root compression giving a triad:
  1. Pain radiating in a dermatomal pattern
  2. Sensory loss/paresthesias in the dermatome
  3. Motor weakness in the myotome + reflex loss
The key exam question is always: "Which level?" - answered by matching the pattern of weakness + sensory loss + reflex change.

PART 1: CERVICAL RADICULOPATHY

Anatomy Concept to Know First

The cervical nerve root exits above its numbered vertebra (C5 root exits between C4-C5). This means:
  • C4-C5 disc herniation → compresses C5 root
  • C5-C6 disc herniation → compresses C6 root
  • C6-C7 disc herniation → compresses C7 root
  • C7-T1 disc herniation → compresses C8 root
Mnemonic: "Cervical roots exit ABOVE = disc number = root below it"
C5, C6, C7 are the most commonly affected roots (levels of greatest cervical mobility and disc degeneration) - as confirmed in Bradley and Daroff's Neurology in Clinical Practice.

Cervical Radiculopathy at a Glance

Cervical radiculopathy - C5, C6, C7, C8 dermatomes, myotomes, and reflexes

The "5-6-7-8 Ladder" - Master Mnemonic for Cervical Roots

RootPain/Sensory areaKey MuscleTest movementReflexMnemonic
C5Shoulder/lateral armDeltoid, BicepsShoulder abductionBiceps"C5 = Shoulder shrug/abDuct"
C6Lateral forearm, thumb + indexBiceps, Brachioradialis, Wrist extensorsElbow flexion + wrist extensionBrachioradialis"C6 = siX-pack thumb (thumb is digit 1=index)"
C7Middle finger, posterior armTriceps, Wrist flexors, PronatorsElbow extensionTriceps"C7 = sEVEn = EXTEND (triceps)"
C8Ring + little finger, medial forearmFinger flexors, IntrinsicsGrip strength / finger flexionNone"C8 = grEIGHt (grip)"
T1Medial upper armIntrinsics (interossei)Finger abduction/adductionNone"T1 = Tiny interossei"
Master Mnemonic: "BiBoTri-No" = C5 Biceps / C6 Brachioradialis / C7 Triceps / C8 No reflex
Or remember: B-B-T going down = Biceps (C5-C6), Brachioradialis (C6), Triceps (C7).

C5 Radiculopathy (C4-C5 disc)

History: Pain from neck → shoulder → lateral arm. Weakness lifting arm overhead. Dermatome: Lateral shoulder, lateral upper arm ("epaulette" area) Myotome weak: Deltoid (shoulder abduction), Biceps, Supraspinatus Reflex lost: Biceps jerk (C5-C6) Tip: Patient cannot comb their hair or lift arm above shoulder. "Shoulder problem, but no neck trauma."
Test: Resisted shoulder abduction - patient holds arm at 90° while you push down.

C6 Radiculopathy (C5-C6 disc) - Most common cervical level

History: Pain down lateral forearm into thumb + index finger. "My thumb goes numb." Dermatome: Lateral forearm, thumb, index finger, lateral half of palm Myotome weak: Biceps (elbow flexion), Brachioradialis, Wrist extensors (ECRL, ECRB) Reflex lost: Biceps jerk AND Brachioradialis jerk Special sign: "Inverted" or "paradoxical" brachioradialis reflex (tap BR → finger flexors contract but no BR contraction = myelopathy at same level)
Test: Resisted elbow flexion + resisted wrist extension

C7 Radiculopathy (C6-C7 disc) - Most common overall

History: Pain to middle finger (± ring finger). Weakness pushing things away ("can't do push-ups"). Subscapular/interscapular pain is classic. Dermatome: Middle finger, dorsal forearm, posterior arm Myotome weak: Triceps, Wrist flexors (FCR, FCU), Pronator teres, Finger extensors Reflex lost: Triceps jerk (ONLY reflex exclusively for C7) Tip: Triceps jerk = C7 exclusively. Test by tapping triceps tendon with elbow at 90°.
Test: Resisted elbow extension

C8 Radiculopathy (C7-T1 disc)

History: Pain/numbness to ring + little finger, medial forearm. Clumsy hand. Dermatome: Medial forearm, ring + little finger Myotome weak: Finger flexors (FDP, FDS), Intrinsic hand muscles, Abductor pollicis brevis Reflex: No dedicated reflex (a common exam trap!) Tip: C8 looks like ulnar nerve but SNAPS are normal in radiculopathy (preganglionic lesion)

T1 Radiculopathy

History: Medial upper arm pain/numbness, intrinsic hand weakness (often Pancoast tumor should be excluded) Dermatome: Medial upper arm, inner elbow Myotome: Intrinsic hand muscles (interossei, lumbricals) Exam: Finger abduction/adduction weakness, look for Horner syndrome (ptosis, miosis, anhidrosis) - suggests Pancoast tumor

Special Provocation Tests for Cervical Radiculopathy

TestTechniqueWhat positive meansSens/Spec
Spurling TestExtend neck + side-bend toward painful side + axial compression downwardReproduces radicular arm painLow sensitivity, HIGH specificity
Cervical Distraction TestPatient supine, lift head with hands under chin/occiputRelief of radicular painModerate sens, high spec
Upper Limb Tension Test (ULTT)Scapular depression + shoulder abduction/flexion + elbow/wrist/finger extension, neck laterally bent awayReproduces arm/hand painHIGH sensitivity (~90%), low specificity
Shoulder Abduction Relief SignPatient raises hand/arm above headRelieves painSpecific for C4-5 or C5-6
Valsalva/CoughIncreases intrathecal pressureWorsens radicular pain-----
From Textbook of Family Medicine: Spurling test = low sens, high spec. Upper limb tension test = sensitivity >90%, low specificity. Straight-leg raise (lumbar) = sensitivity 91%, specificity 26%.
Mnemonic for Spurling: "SPECific for radiculopathy" = Spurling = SPECificity

PART 2: LUMBOSACRAL RADICULOPATHY

Key Anatomy Concept

In the lumbar region, roots exit below their numbered vertebra (unlike cervical). However, the disc at L4-L5 typically compresses the traversing L5 root (not L4), because L4 exits at L4-L5 foramen:
  • L3-L4 disc → compresses L4 root (exiting at L3-L4 foramina) or traversing L4
  • L4-L5 disc herniation → usually compresses traversing L5 root
  • L5-S1 disc herniation → usually compresses traversing S1 root
Most common: S1 (from L5-S1 disc) and L5 (from L4-L5 disc)

Lumbosacral Radiculopathy Table

L4, L5, S1 disc herniations with clinical findings and cauda equina

Body Dermatome Map

Full body dermatome map showing T4=nipples, T10=umbilicus, L4=medial leg, L5=dorsum foot, S1=lateral foot

Lumbar Root Summary Table

RootDisc LevelPain PatternKey WeaknessReflex LostSensory AreaMnemonic
L2L1-L2Anterior thighHip flexionNoneAnterior/medial upper thigh"L2 = Loin to groin"
L3L2-L3Anterior thigh → medial kneeKnee extension, hip adductionPatellar (partial)Anterior thigh + medial knee"L3 = Leg thREE, thigh/knee"
L4L3-L4Anterior thigh → medial shinKnee extension (quads), foot inversionPatellar/Knee jerkMedial lower leg"L4 = 4ward = kneecap"
L5L4-L5Buttock → lateral leg → dorsum foot → big toeFoot/great toe dorsiflexion (EHL), hip abductionAnkle jerk (sometimes, medial)Lateral leg, dorsum foot, big toe"L5 = L5ift foot up, big toe"
S1L5-S1Buttock → posterior thigh → lateral footPlantar flexion (calf), eversionAnkle jerk / AchillesPosterior thigh, calf, lateral foot/heel"S1 = Soles of feet, Sole=S1, Ankle jerk"
S2-4-Perineum, inner thighsBladder/bowel, sphinctersBulbocavernosus/analSaddle area"S2,3,4 keeps the poo off the floor"

Lumbosacral Root Mnemonics

"2-3-4 in front, 5-1 behind"
  • L2, L3, L4 radiculopathies → pain anteriorly (anterior thigh, medial leg) - tested by Femoral nerve stretch test
  • L5, S1 → pain posteriorly (buttock, posterior leg) - tested by Straight Leg Raise (SLR)

Key Reflex Mnemonics

ReflexRootMnemonic
BicepsC5-C6"B5-6 = Biceps 5 and 6"
BrachioradialisC6"BR = Brachioradialis = Rad-6"
TricepsC7"Tri7 = Triceps C7"
Patellar (knee jerk)L3-L4"Patellar = L3-L4, knee goes fore"
Achilles (ankle jerk)S1"Aching S1 ankle" or "S1 = Sole/Achilles"

The "L4-L5-S1 Clinical Triad" (Exam Favourite)

FeatureL4L5S1
WeaknessKnee extension, foot inversionDorsiflexion of foot/big toePlantar flexion (stand on tiptoe)
SensoryMedial shinDorsum foot, big toeLateral foot, heel
ReflexKnee jerk ↓Ankle jerk (sometimes) or absentAnkle jerk ↓
Quick testWalk on heels (tests L4/L5)Cannot lift big toeCannot stand on tiptoes
DiscL3-L4L4-L5L5-S1
Memory hook:
  • L4 = "4wards walking" = knee extension, heel walking
  • L5 = "L5ft the foot up" = dorsiflexion, extensor hallucis longus (EHL)
  • S1 = "S1 = Sole" = plantar flexion, ankle jerk

Clinical Provocation Tests for Lumbosacral Radiculopathy

TestTechniqueRoots testedSens/Spec
Straight Leg Raise (SLR / Lasègue)Supine, passively raise straight leg. Positive: radicular pain at 30-70° (NOT just back pain)L5, S1Sensitivity 91%, specificity 26%
Crossed SLRRaising the contralateral leg reproduces ipsilateral radicular painL5, S1Low sensitivity, high specificity (~90%)
Femoral Nerve Stretch TestProne, flex knee to 90°, extend hip. Positive: anterior thigh painL2, L3, L4For upper lumbar roots
Slump TestSeated, slump forward + extend knee + dorsiflex ankle. Positive: sciatic painL5, S1High sensitivity
Bowstring SignAfter positive SLR, flex knee slightly - if pain returns with popliteal fossa pressure, positiveL5, S1High specificity
Key from Rheumatology textbook: Femoral stretch test = L2/L3/L4; SLR/Bowstring = L5/S1
Mnemonic: "SLR for LOW (L5-S1 = low lumbar), Femoral for HIGH (L2-3-4 = upper lumbar)"

PART 3: RED FLAGS (Cauda Equina - Must Not Miss!)

Cauda equina syndrome = massive central disc herniation (usually L4/5 or L5/S1) compressing multiple roots:
  • Bilateral leg pain/weakness
  • Saddle anesthesia (S2-4 dermatome - perineum, inner thighs)
  • Bladder retention or incontinence (most reliable sign)
  • Anal sphincter laxity (loss of anal tone)
  • Decreased/absent bilateral ankle jerks
"Saddle + Bladder = Emergency Surgery" - From Bradley and Daroff's and Textbook of Family Medicine: sphincter disturbance from lumbar disease requires urgent surgical consideration.
Historical red flags for any back pain:
  • Fever, weight loss (infection/malignancy)
  • History of cancer
  • Bowel/bladder dysfunction (CES)
  • Saddle anesthesia
  • Bilateral leg weakness
  • Recent major trauma
  • IV drug use / immunosuppression

PART 4: DIAGNOSTIC INVESTIGATIONS

TestRadiculopathy FindingNotes
MRI spineDisc herniation or osteophyte compressing rootInvestigation of choice
CT myelographySame as MRI; better for calcified lesions, post-op patientsIf MRI contraindicated
NCSNormal SNAPs (lesion is preganglionic, proximal to DRG)Differentiates from peripheral neuropathy
EMG (needle)Fibrillations/PSWs in myotome distribution + paraspinalsConfirms radiculopathy; paraspinals are key
F-wavesMay be delayed in affected rootLess sensitive
H-reflexAbsent/asymmetric = S1 radiculopathy (sensitivity 50%, specificity 91%)Very specific for S1
Key NCS point for exams: In radiculopathy, the dorsal root ganglion (DRG) is outside the spinal canal, so sensory axons peripheral to the DRG are intact → SNAPs normal despite sensory symptoms. CMAPs may be reduced if significant motor axon loss. This distinguishes radiculopathy from peripheral neuropathy/plexopathy.
"Normal SNAP = preganglionic = radiculopathy" - Bradley and Daroff's Neurology

PART 5: MASTER MEMORY TABLE

Upper Limb Reflexes - "BiBoTri No" Mnemonic

C5 = Biceps (and Brachioradialis shares)
C6 = Brachioradialis (and Biceps shares)
C7 = Triceps (exclusive)
C8 = Nothing (no reflex)

Lower Limb Reflexes

L3-L4 = Patellar (knee jerk)  → "kneecap = L34"
S1    = Achilles (ankle jerk) → "sole/ankle = S1"

PART 6: DERMATOMAL KEY LANDMARKS (USMLE/MRCP Favourites)

LandmarkRoot
Nipple lineT4
Xiphoid processT7
UmbilicusT10
Groin / inguinal ligamentL1
Anterior thighL2-L3
Medial shin/kneeL4
Dorsum of foot / big toeL5
Lateral foot / heel / soleS1
Perineum / saddle areaS2-S4
Thoracic landmarks mnemonic: "T4 = Tits (nipples), T10 = TEN = Tummy button (umbilicus)"

PART 7: HISTORY TAKING - THE RADICULOPATHY TEMPLATE

A structured history for FCPS/MRCP/USMLE OSCEs:
  1. Character of pain: burning, shooting, lancinating (neuropathic quality)
  2. Radiation: Does it radiate beyond the knee (lumbar) or elbow (cervical)?
  3. Aggravating factors: Cough/sneeze/Valsalva worsens → increased intrathecal pressure → radiculopathy
  4. Relieving factors: Arm raised above head relieves cervical pain (shoulder abduction relief sign)
  5. Duration and onset: Acute (disc) vs. gradual (spondylosis/stenosis)
  6. Neurological symptoms: Numbness, tingling in which finger/toe?
  7. Weakness: Specific activities - can't open jars (C8/T1), can't comb hair (C5), can't walk on tiptoes (S1), dragging foot (L5)
  8. Red flags: Bilateral, bowel/bladder, saddle numbness

Quick Summary Card for Exams

Cervical

  • C5: Shoulder abduction weak, Biceps reflex ↓, lateral arm numb
  • C6: Elbow flex + wrist extend weak, Brachioradialis reflex ↓, thumb/index numb - most common
  • C7: Elbow extend weak, Triceps reflex ↓, middle finger numb
  • C8: Finger flex weak, NO reflex, ring/little finger numb
  • Spurling = high spec, ULTT = high sens

Lumbosacral

  • L4: Quad/knee extend weak, Knee jerk ↓, medial shin numb, heel walk
  • L5: Foot/big toe dorsiflex weak (EHL), ankle jerk sometimes ↓, dorsum foot/big toe numb
  • S1: Plantar flex weak (calf), Ankle jerk ↓, lateral foot numb, tiptoe test
  • SLR tests L5/S1 (high sens), Femoral stretch tests L2/L3/L4 (high spec)
  • Cauda equina = saddle anesthesia + bladder = EMERGENCY

Sources: Bradley and Daroff's Neurology in Clinical Practice (cervical radiculopathy chapters); Textbook of Family Medicine 9e (spine physical examination tables); Lecturio medical illustrations; neurological examination evidence from PMC scoping review on cervical radiculopathy.
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