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Posterior MI - ECG Indications & Clinical Features
Anatomy & Epidemiology
Posterior MI accounts for 15-20% of all AMIs and usually occurs with inferior or inferolateral infarctions. Isolated posterior MI (showing ST elevation only in posterior leads V7-V9) accounts for ~5% of AMI cases.
Culprit vessels:
- Right coronary artery (RCA) or its posterior descending branch
- Left circumflex artery (LCx) - nondominant; isolated posterior MI is typically a nondominant LCx occlusion
Note: Cardiac MRI evidence suggests these so-called "posterior" infarctions actually involve the lateral left ventricular wall. A consensus document now recommends reclassifying them as inferobasal MI.
ECG Indications (12-Lead)
Because no standard leads directly face the posterior wall, diagnosis relies on reciprocal (mirror-image) changes in right precordial leads V1-V3:
| ECG Finding | Leads | Significance |
|---|
| Horizontal ST depression | V1-V3 | Most important sign; mirror of posterior ST elevation |
| Upright (tall) T wave | V1-V3 | Posterior T-wave inversion seen as upright anteriorly |
| Tall, broad R wave (≥0.04 sec in V1-V2) | V1-V2 | Mirror image of posterior Q wave; may be delayed |
| R/S ratio ≥1 with positive T wave | V1-V2 | Suggests prior posterior MI (absent RVH or RBBB) |
The combination of horizontal ST depression + upright T wave in V1-V3 increases diagnostic accuracy significantly.
The ECG above shows a classic inferior MI with posterior extension - note the ST depression in V1-V3.
Posterior Leads (V7-V9) - Confirmatory
Extending the ECG with posterior leads V7-V9 increases sensitivity for detecting LCx-related injury:
- ST elevation ≥0.5 mm in V7-V9 = direct evidence of posterior wall injury
- Leads are placed at the posterior left chest (V7: posterior axillary line, V8: tip of scapula, V9: left paraspinal)
- Tintinalli recommends placing V7-V9 specifically when posterior MI is suspected from circumflex lesion
Key Clinical Indications to Suspect Posterior MI
- ST depression in V1-V3 without anterior ischemic symptoms - think posterior MI
- Inferior STEMI (II, III, aVF) with V1-V3 depression - posterior extension increases infarct size, lowers EF, worsens outcomes
- Tall dominant R in V1 without other explanation (no RVH, no RBBB, no WPW)
- Isolated LCx territory ischemia - the LCx is "ECG silent" on the standard 12-lead; posterior leads essential
Treatment Implications
- Posterior MI qualifies as STEMI equivalent - immediate reperfusion (PCI preferred)
- Fibrinolytic therapy is generally contraindicated in ST-depression UNLESS posterior MI is suspected (Washington Manual: fibrinolytics are contraindicated "in patients with ECG evidence of ST-segment depressions, unless posterior MI suspected")
- Posterior MI with inferior involvement: order right-sided leads (V4R) simultaneously to rule out RV infarction (affects management - avoid nitrates, preload-dependent state)
Association with Right Ventricular Infarction
Proximal RCA occlusion can cause inferior + posterior + RV infarction simultaneously. In patients with inferior STEMI + posterior extension:
- Larger infarct zone, lower ejection fraction
- Higher cardiovascular morbidity and mortality than isolated inferior MI
- ST elevation in V1 with inferior STEMI + V4R elevation = concomitant RV infarction
Sources: Rosen's Emergency Medicine, p. 1006 | Goldman-Cecil Medicine | Washington Manual of Medical Therapeutics