https://www.jbjs.org/reader.php?rsuite_id=2699881&type=pdf&name=JBJS.20.00275.pdf make a journal club presentation for me in these headings 1) Journal details with impact factor 2) Introduction 3) aim 4)methods and materials 5) Inclusion. and exclusion criteria 6) statistical analysis 7) Outcome measures 8) Results 9)Conclusion 10) Study limitations 11) References
https://www.jbjs.org/reader.php?rsuite_id=2699881&type=pdf&n…
JBJS 2021 volar locking plate external fixation distal radial fracture RCT JBJS.20.00275
volar locking plate external fixation distal radial fracture randomized controlled trial
PMID: 33369985
Journal of Bone and Joint Surgery JBJS impact factor 2024 2025
mkdir -p /home/daytona/workspace/journal-club && ls /home/daytona/workspace/journal-club/
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pres.title = "Journal Club – VLP vs EF for Distal Radial Fractures";
pres.author = "Journal Club";
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["Journal", "The Journal of Bone & Joint Surgery (JBJS) – American Volume"],
["ISSN", "0021-9355 (print) | 1535-1386 (online)"],
["Publisher", "The Journal of Bone and Joint Surgery, Inc."],
["Frequency", "Bi-weekly (24 issues/year)"],
["Impact Factor", "4.3 (2024) – #1 in citations in Orthopaedics"],
["Indexing", "MEDLINE/PubMed, EMBASE, Scopus, Web of Science"],
["Scope", "Evidence-based orthopaedic surgery research worldwide"],
["Article Type", "Level I Multicenter Randomized Controlled Trial"],
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"Distal radial fractures are the most common fractures managed by orthopaedic surgeons, representing ~15% of all fractures presenting to emergency departments.",
"Two dominant surgical strategies exist for displaced, unstable extra-articular fractures (OTA/AO type A3):\n ▸ Volar Locking Plate (VLP) – internal fixation with a palmar plate\n ▸ External Fixation (EF) – spanning or non-spanning frame fixation",
"Over the past two decades, VLP use has risen dramatically, replacing EF as the preferred technique in many centres worldwide.",
"This shift has been driven primarily by theoretical advantages (stable fixation, early mobilisation) rather than robust Level I evidence.",
"Multiple earlier RCTs and meta-analyses produced conflicting results or were underpowered, leaving the optimal surgical approach for extra-articular distal radial fractures uncertain.",
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"Compare patient-reported pain and disability (QuickDASH, VAS) between the two groups over 1 year",
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// SLIDE 5 – Methods & Materials
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"Design: Multicenter, parallel-group RCT",
"Centres: Haukeland University Hospital & Voss Hospital, Norway",
"Period: 2013–2017",
"Registration: ClinicalTrials.gov (NCT01904084)",
"Ethics: Declaration of Helsinki; ethics committee approved",
"Allocation: Computer-generated 1:1 randomisation with sealed envelopes; stratified by centre and surgeon",
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"Intervention A – VLP: Volar locking plate fixation; early mobilisation from 3–5 days post-op",
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"Follow-up: 6 weeks, 3 months, 1 year",
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"Presenting to Haukeland University Hospital or Voss Hospital (2013–2017)",
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// SLIDE 7 – Statistical Analysis
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"Sample Size: 75 patients per group (150 total) calculated to detect a 10-point difference in PRWHE at 6 weeks with 80% power (α = 0.05), accounting for 10% dropout.",
"Primary Analysis: Mixed-model ANOVA for repeated measures on patient-reported outcome measure (PROM) data – PRWHE, QuickDASH, and VAS scores – to account for within-subject correlation across time points.",
"Continuous Variables: Student's t-test for non-PROM continuous outcomes at individual time points.",
"Categorical Variables: Chi-square (χ²) test for categorical data (e.g., complication rates, reoperation).",
"Analysis Principle: Intention-to-treat (ITT) for all analyses – patients analysed in the group to which they were originally randomised, regardless of protocol adherence.",
"Missing Data: Handled within the mixed-model framework; patients with at least one follow-up visit were included.",
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{ text: "\nGrip Strength", bold: true }, { text: " — Jamar dynamometer; reported as % of contralateral side", bold: false },
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// ════════════════════════════════════════════════════════════════
// SLIDE 9 – Results (Part A – Patient Flow & Primary Outcome)
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[{ text: "3 Months" }, { text: "–" }, { text: "–" }, { text: "0.069 (NS)" }],
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// ════════════════════════════════════════════════════════════════
// SLIDE 10 – Results (Part B – Secondary Outcomes)
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{ text: "6 Weeks", options: { bold: true, color: WHITE, fill: { color: SECTION_HDR } } },
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[{ text: "QuickDASH" }, { text: "VLP 27 vs EF 43\np < 0.001" }, { text: "VLP better\np = 0.023" }, { text: "NS" }],
[{ text: "Wrist Flexion" }, { text: "VLP 49° vs EF 39°\np < 0.001" }, { text: "VLP 62° vs EF 57°\np = 0.009" }, { text: "NS (p = 0.66)" }],
[{ text: "Wrist Extension" }, { text: "VLP 43° vs EF 3°\np < 0.001" }, { text: "VLP better\np = 0.004" }, { text: "VLP better\np = 0.013" }],
[{ text: "Supination" }, { text: "VLP 63° vs EF 37°\np < 0.001" }, { text: "VLP better\np = 0.034" }, { text: "NS" }],
[{ text: "VAS (activity)" }, { text: "NS at 6 wks" }, { text: "VLP better\np = 0.023" }, { text: "VLP better\np = 0.026" }],
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// ════════════════════════════════════════════════════════════════
// SLIDE 11 – Conclusion
// ════════════════════════════════════════════════════════════════
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{ head: "Early Recovery Advantage:", body: " VLP provides significantly better functional outcomes (PRWHE, QuickDASH, ROM) at 6 weeks and persisting into 3 months." },
{ head: "Equivalence at 1 Year:", body: " No significant difference in primary or most secondary outcomes at 1 year, suggesting both techniques deliver similar long-term results." },
{ head: "Wrist Extension:", body: " VLP maintained a statistically significant advantage in wrist extension at 1 year (64° vs 59°, p = 0.013) – a clinically relevant finding for activities of daily living." },
{ head: "Complication Profile:", body: " Major complication rates were comparable (VLP 23% vs EF 25%), but plate removal was exclusively a VLP problem (7%, p = 0.025)." },
{ head: "Evidence Implication:", body: " This Level I RCT supports VLP as the preferred technique when early return to function is a priority, but EF remains a valid alternative with similar 1-year outcomes." },
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// ════════════════════════════════════════════════════════════════
// SLIDE 12 – Study Limitations
// ════════════════════════════════════════════════════════════════
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const s = addContentSlide("10. Study Limitations");
bullets(s, [
"Lack of blinding for surgeons and patients (inherent to surgical RCTs) – potential for performance and detection bias.",
"Single-country design (Norway): patient demographics, surgical expertise, and rehabilitation protocols may limit generalisability to other healthcare settings.",
"Female predominance (89%): findings may not fully apply to younger male patients or athletes with higher functional demands.",
"Limited to extra-articular fractures (OTA/AO type A3) only – conclusions cannot be extrapolated to intra-articular or comminuted patterns.",
"Loss to follow-up: 14 patients (9%) did not complete 1-year assessment; although ITT was used, this may introduce some bias.",
"No formal health-economic analysis: cost comparison between VLP (expensive implant, no routine removal) and EF was not performed.",
"Minimum follow-up 1 year: long-term outcomes (arthritis, tendon rupture, hardware failure beyond 1 year) remain unknown.",
"Variability in EF technique: addition of adjuvant K-wires was at surgeon discretion, introducing heterogeneity in the EF arm.",
"VLP plate removal in 7% represents an underappreciated complication and added cost that should inform shared decision-making."
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"1. Ludvigsen T, Matre K, Gudmundsdottir RS, et al. Surgical Treatment of Distal Radial Fractures with External Fixation Versus Volar Locking Plate: A Multicenter Randomized Controlled Trial. J Bone Joint Surg Am. 2021;103(5):405–414. DOI: 10.2106/JBJS.20.00275. PMID: 33369985.",
"2. Margaliot Z, Haase SC, Kotsis SV, et al. A meta-analysis of outcomes of external fixation versus plate osteosynthesis for unstable distal radius fractures. J Hand Surg Am. 2005;30(6):1185–1199.",
"3. Williksen JH, Frihagen F, Hellund JC, et al. Volar locking plates versus external fixation and adjuvant pin fixation in unstable distal radius fractures: a randomized controlled study. J Hand Surg Am. 2013;38(8):1469–1476.",
"4. Wei DH, Raizman NM, Bottino CJ, et al. Unstable distal radial fractures treated with external fixation, a radial column plate, or a volar plate. A prospective randomized trial. J Bone Joint Surg Am. 2009;91(7):1568–1577.",
"5. Orbay JL, Fernandez DL. Volar fixed-angle plate fixation for unstable distal radius fractures in the elderly patient. J Hand Surg Am. 2004;29(1):96–102.",
"6. Wilcke MK, Abbaszadegan H, Adolphson PY. Wrist function recovers more rapidly after volar locked plating than after external fixation but the outcomes are similar after 1 year. Acta Orthop. 2011;82(1):76–81.",
"7. Cui Z, Pan J, Yu B, et al. Internal versus external fixation for unstable distal radius fractures: an up-to-date meta-analysis. Int Orthop. 2011;35(9):1333–1341.",
"8. MacDermid JC, Turgeon T, Richards RS, et al. Patient rating of wrist pain and disability: a reliable and valid measurement tool. J Orthop Trauma. 1998;12(8):577–586.",
"9. Beaton DE, Wright JG, Katz JN. Development of the QuickDASH: comparison of three item-reduction approaches. J Bone Joint Surg Am. 2005;87(5):1038–1046.",
"10. ClinicalTrials.gov Identifier: NCT01904084. External Fixation Versus Volar Locking Plate in Distal Radial Fractures."
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cd /home/daytona/workspace/journal-club && node build.js 2>&1
~/journal-club/build.js
Successfully replaced 1 instance(s) of the string in '/home/daytona/workspace/journal-club/build.js'
cd /home/daytona/workspace/journal-club && node build.js 2>&1
VLP vs EF Journal Club
Presentation · PPTX
| # | Slide | Content |
|---|---|---|
| 1 | Title | Full paper title, authors, journal, DOI |
| 2 | Journal Details & Impact Factor | JBJS impact factor 4.3 (2024), #1 in orthopaedic citations, indexing, volume/issue |
| 3 | Introduction | Epidemiology of distal radial fractures, evolution from EF to VLP, lack of Level I evidence |
| 4 | Aim | Primary aim + 4 secondary objectives |
| 5 | Methods & Materials | Multicenter RCT design (2013-2017), randomisation, blinding, interventions, follow-up protocol |
| 6 | Inclusion & Exclusion Criteria | Two-column layout - OTA/AO type A3, age 18-70 yrs vs dementia, mental illness, open fractures etc. |
| 7 | Statistical Analysis | Sample size calculation, mixed-model ANOVA, Student's t-test, chi-square, ITT principle, SPSS v26 |
| 8 | Outcome Measures | PRWHE (primary), QuickDASH, VAS, ROM, grip strength, radiographs, complications |
| 9 | Results (A) | Patient flow (156 enrolled, 142 completed), PRWHE table across time points |
| 10 | Results (B) | Full secondary outcomes table - QuickDASH, ROM, VAS, complications |
| 11 | Conclusion | 5 key take-home messages in formatted boxes |
| 12 | Study Limitations | 9 limitations including lack of blinding, single-country design, female predominance, 1-year cap |
| 13 | References | 10 references including the index paper (PMID 33369985) |
make the contents for each side
~/journal-club/build.js
Successfully replaced 1 instance(s) of the string in '/home/daytona/workspace/journal-club/build.js'
cd /home/daytona/workspace/journal-club && node build.js 2>&1
VLP vs EF Journal Club
Presentation · PPTX
You give me as a text I will type in on my slides
| Parameter | Details |
|---|---|
| Journal | The Journal of Bone & Joint Surgery (JBJS) – American Volume |
| ISSN | 0021-9355 (print) / 1535-1386 (online) |
| Publisher | The Journal of Bone and Joint Surgery, Inc. |
| Frequency | Bi-weekly (24 issues/year) |
| Impact Factor | 4.3 (2024) – #1 in citations in Orthopaedics |
| Indexing | MEDLINE/PubMed, EMBASE, Scopus, Web of Science |
| Scope | Evidence-based orthopaedic surgery research worldwide |
| Article Type | Level I Multicenter Randomized Controlled Trial |
| Published | Volume 103-A, Number 5, March 3, 2021 (pp. 405–414) |
| DOI / PMID | 10.2106/JBJS.20.00275 / PMID: 33369985 |
10° dorsal angulation of the joint line
| Time Point | VLP (Median) | EF (Median) | p-value |
|---|---|---|---|
| 6 Weeks | 27 | 44 | < 0.001 (significant) |
| 3 Months | – | – | 0.069 (not significant) |
| 1 Year | – | – | 0.233 (not significant) |
| Outcome | 6 Weeks | 3 Months | 1 Year |
|---|---|---|---|
| QuickDASH | VLP 27 vs EF 43 (p < 0.001) | VLP better (p = 0.023) | Not significant |
| Wrist Flexion | VLP 49° vs EF 39° (p < 0.001) | VLP 62° vs EF 57° (p = 0.009) | Not significant (p = 0.66) |
| Wrist Extension | VLP 43° vs EF 3° (p < 0.001) | VLP better (p = 0.004) | VLP better (p = 0.013) |
| Supination | VLP 63° vs EF 37° (p < 0.001) | VLP better (p = 0.034) | Not significant |
| VAS (activity) | Not significant | VLP better (p = 0.023) | VLP better (p = 0.026) |
| Major Complications | – | – | VLP 23% vs EF 25% (p = 0.83, NS) |
Time period of study?
what is prwhe
| Subscale | Questions | What it measures |
|---|---|---|
| Pain | 5 items | Pain at rest, with specific activities, at its worst, usual pain, etc. |
| Function | 10 items | Specific activities (6 items) + usual activities (4 items) |
What does QuickDASH measure and how does it differ from PRWHE?0,11?
| Feature | QuickDASH | PRWHE |
|---|---|---|
| Full name | Quick Disabilities of Arm, Shoulder & Hand | Patient-Rated Wrist & Hand Evaluation |
| No. of items | 11 | 15 |
| Body region | Entire upper limb (shoulder → hand) | Wrist and hand only |
| Specificity | Broad – any upper limb condition | Specific – wrist conditions |
| Subscales | None (single score) | Pain + Function (two subscales) |
| Score range | 0–100 (0 = best) | 0–100 (0 = best) |
| MCID | ~15 points | ~14 points |
| Developed by | Beaton et al. (2005) | MacDermid et al. (1998) |
| Best used for | Comparing across upper limb conditions | Wrist-specific research |
| Role in this study | Secondary outcome | Primary outcome |
can u give me presenters notes for slide 8 to 11?
keep the presenter notes short
but in slide 11, why plate removal for ef group?
discussion?
Presenetrs notes for conclusion and limitations - short and sweet
references any 4 papers should compare and tell me the result
volar locking plate external fixation distal radius fracture randomized controlled trial
PMID: 33980198
PMID: 25914018
PMID: 26709818
PMID: 23594247
| Study | Design | n | Follow-up | VLP better early? | Equal at 1 year? | Agrees with Ludvigsen? |
|---|---|---|---|---|---|---|
| Xie 2013 | Meta-analysis | 10 RCTs | 12 months | Yes | Yes | Yes |
| Williksen 2015 | RCT | 111 | 5 years | Yes | Yes (5 yrs) | Yes — plate removal higher (21%) |
| Mellstrand Navarro 2016 | RCT | 140 | 12 months | Yes (QoL) | Yes | Yes |
| Gou 2021 | Meta-analysis | 1,205 | 12 months | Yes | Partial disagreement | Partially — includes intra-articular |
from the reference u have given before, kindly compare and let me know the results
| Ref | Authors | Year | Design | n | Follow-up | VLP better early? | Equal at 1 year? | Vs Ludvigsen |
|---|---|---|---|---|---|---|---|---|
| 1 | Ludvigsen | 2021 | RCT | 156 | 1 yr | Yes | Yes | Index paper |
| 2 | Margaliot | 2005 | Meta-analysis | Multiple | 12 mo | Yes | No — favoured VLP | Contradicts |
| 3 | Williksen | 2013 | RCT | 111 | 1 yr | Yes | Yes | Agrees |
| 4 | Wei | 2009 | RCT (3 arms) | 88 | 1 yr | Yes | Yes | Agrees |
| 5 | Orbay | 2004 | Case series | Small | Short | N/A | N/A | Technique paper |
| 6 | Wilcke | 2011 | RCT | 80 | 1 yr | Yes | Yes | Agrees |
| 7 | Cui | 2011 | Meta-analysis | Multiple | 12 mo | Yes | Partial | Partially contradicts |
| 8 | MacDermid | 1998 | Validation | — | — | — | — | PRWHE tool paper |
| 9 | Beaton | 2005 | Validation | — | — | — | — | QuickDASH tool paper |
| 10 | NCT01904084 | — | Registration | — | — | — | — | Ludvigsen's own protocol |
short and sweet for slide
| Author | Year | Design | Key Finding | Agrees with Ludvigsen? |
|---|---|---|---|---|
| Williksen | 2013 | RCT n=111 | VLP better at 3 months, equal at 1 year. Plate removal 21% in VLP | ✅ Yes |
| Wei | 2009 | RCT n=88 | No difference in DASH at 1 year. EF had more pin-site infections | ✅ Yes |
| Wilcke | 2011 | RCT n=80 | VLP faster recovery at 3 months, equal at 1 year | ✅ Yes |
| Margaliot | 2005 | Meta-analysis | VLP superior in function and fewer complications | ⚠️ Partially |
| Cui | 2011 | Meta-analysis | VLP better DASH at 3, 6, 12 months | ⚠️ Partially |
| Orbay | 2004 | Case series | VLP gives good early mobilisation and anatomical restoration | ➡️ Technique paper |
pivd vs lcs how the differentiate in history
| Feature | PIVD | LCS |
|---|---|---|
| Age | Younger (20–45 years) | Older (>50 years) |
| Onset | Sudden — after lifting, bending, twisting | Gradual — insidious over months/years |
| Pain character | Sharp, shooting, electric shock-like | Dull, aching, cramping, heaviness |
| Radiation | Follows a specific dermatomal pattern (L4, L5, S1) | Bilateral, diffuse, poorly localised — both legs |
| Back pain vs leg pain | Back pain + leg pain — leg pain often dominant | Leg pain dominant — back pain may be mild or absent |
| Posture effect on pain | Worse on sitting, forward bending, Valsalva | Worse on standing and walking |
| Relief of pain | Lying flat relieves pain | Sitting or bending forward relieves pain |
| Walking | Can walk but pain radiates down leg | Cannot walk far — stops due to leg pain/heaviness |
| Cycling | Painful — flexion may aggravate | Comfortable on cycling — forward lean opens canal |
| Shopping trolley sign | Absent | Present — leans forward on trolley for relief |
| Neurogenic claudication | Absent | Present — hallmark of LCS |
| Bladder/bowel | Only in massive central disc prolapse | Can occur in severe stenosis |
| Rest pain | Common | Absent at rest |
Pain is position-specific — worse sitting, better lying flat. One leg affected.
Pain comes on with walking a fixed distance, relieved by sitting or stooping forward. Both legs affected.
| PIVD | LCS | |
|---|---|---|
| Sitting | Worse | Better |
| Walking | Possible | Limited |
| Cycling | Worse | Fine |
| Age | Young | Old |
| Legs affected | One | Both |
"Young person, one leg, sitting hurts = PIVD" "Old person, both legs, can't walk but can cycle = LCS"
how to elaborate the h/o activities of daily living in spine history presentation
"With regard to activities of daily living, the patient is significantly limited. He can walk only about 100 metres on flat ground before bilateral leg heaviness forces him to stop and sit. He is unable to stand for more than 5 minutes. Sitting tolerance is about 20 minutes. He requires assistance to wear his socks and footwear. He has been on sick leave from his job as a driver for the past 2 months. He sleeps on his side with knees bent and denies any night pain. There is no difficulty with bladder or bowel function and no perianal numbness."
| Letter | Domain |
|---|---|
| M | Mobility / walking distance |
| I | Independence in self-care (dressing, bathing) |
| S | Sitting and standing tolerance |
| S | Sleep |
| A | Ambulation aids |
| D | Domestic and occupational activity |
| O | Orifices — bladder and bowel |
| S | Social and recreational activities |
how many meters do we call it as neurogenic claudication
1. Pain/heaviness/numbness in legs brought on by walking or standing 2. Relieved by sitting or stooping forward 3. Recurs on walking the same distance again
"He develops bilateral leg pain, heaviness and numbness after walking approximately 100 metres on flat ground, which forces him to stop. The symptoms are completely relieved after sitting for about 5 minutes, following which he can walk the same distance again. He is able to cycle without any symptoms."
| Severity | Walking Distance |
|---|---|
| Mild | > 500 metres |
| Moderate | 100–500 metres |
| Severe | < 100 metres |
The distance is a measure of severity. The pattern is the diagnosis.
instability pain how can I ask in history
"The pain is worst when I get up from sitting — the first few steps are terrible. Once I get going it settles a bit. If I sit or stand too long it starts again. Turning over in bed wakes me up. I have to hold the armrest to get out of a chair. I feel much more comfortable when I wear my lumbar belt."
| Feature | Instability Pain | Disc Pain (PIVD) | Stenosis (LCS) |
|---|---|---|---|
| Worst with | Transitional movement | Sustained sitting / flexion | Walking / standing |
| Relieved by | Stillness, support, brace | Lying flat | Sitting / stooping |
| Night pain | Turning over in bed | Lying flat may help | Usually absent |
| Start-up pain | Yes — classic | Less typical | No |
| Giving way feeling | Yes | No | No |
| Brace helps | Yes — significantly | Partially | Minimal |
"Instability pain is characterised by start-up pain, transition pain, a catching or giving-way sensation, pain on turning in bed, and significant relief with a lumbar support or brace."
blood supply of the hip joint