Evidence for prehabilitation in cancer patients

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cancer AND prehabilitation

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cancer AND prehabilitation

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cancer prehabilitation guideline preoperative 2025

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PMID: 39438910

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PMID: 41549884

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PMID: 37978411

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colorectal cancer AND prehabilitation

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https://macmillan.org.uk/healthcare-professionals/cancer-pat…

Bottom line

Cancer prehabilitation is reasonable supportive care, particularly for improving pre-treatment fitness, functional capacity, and psychological readiness. Evidence that it consistently reduces major postoperative complications, length of stay, or readmissions is mixed and low-certainty, largely because interventions, cancer types, and outcomes differ substantially across studies.
Prehabilitation should therefore be offered as an individualised, needs-based multimodal program, not as a replacement for standard perioperative oncology care or a reason to delay time-sensitive cancer treatment.

What it includes

Usually started after diagnosis and before surgery, chemotherapy, or radiotherapy, often continuing through treatment:
  • Exercise: aerobic, resistance, mobility, and, where appropriate, inspiratory-muscle training.
  • Nutrition: screening for malnutrition, dietetic support, protein/energy optimisation, management of symptoms impairing intake.
  • Psychological and behavioural support: anxiety management, sleep, smoking/alcohol cessation, coping skills, education, and goal-setting.
  • Medical optimisation: anaemia, frailty, comorbidities, cardiopulmonary status, and medication review.
Macmillan's 2025 clinical and implementation guidance defines it as a needs-based multimodal intervention to optimise physical, nutritional, and psychological health before and during treatment. See its professional prehabilitation guidance.

Evidence by outcome

OutcomeOverall evidence
Exercise capacity / physical functionMost consistent benefit. A 2024 meta-analysis of RCTs found improved 6-minute walk distance by 38.5 m (95% CI 33.0-44.0).
Anxiety and depressionSmall but statistically significant improvements in HADS anxiety and depression scores in the same meta-analysis.
Muscle strength, respiratory function, quality of lifeOften improve, especially short term, but results vary between programmes and cancer populations.
Postoperative complications and length of stayPromising in some colorectal and minimally invasive-surgery studies, but no consistent pooled benefit across all cancers.
Frailty subgroupA 2026 systematic review found no statistically significant reduction in length of stay, complications, functional decline, or readmission.
Adherence and implementationMajor real-world limitations: referral timing, fatigue, transport, socioeconomic barriers, competing appointments, and short intervals before treatment.

Key systematic-review evidence

  • [Systematic review and meta-analysis . Tier 1 . 2024] Gennuso et al. reviewed 42 studies, with 13 in meta-analysis. It reported better 6-minute walk distance and lower anxiety/depression scores, alongside signals for shorter hospital stay and improvements in endurance, strength, respiratory function, and quality of life. However, the authors judged the included trials to have substantial risk of bias. BMC Cancer. PMID: 39438910.
  • [Systematic review . Tier 1 . 2023] Meneses-Echavez et al. included 25 RCTs and 2,682 participants, mainly colorectal and lung cancer. They concluded that exercise-based prehabilitation may help, but certainty for quality of life, strength, complications, and hospital stay was very low, due to bias and imprecision. Systematic Reviews. PMID: 37978411.
  • [Systematic review and meta-analysis . Tier 1 . 2026] Hoff et al. examined 15 studies in frail patients undergoing cancer surgery. There was no statistically significant effect on length of stay, complications, postoperative function, or readmission, with marked heterogeneity in frailty definitions and intervention protocols. Internal Medicine Journal. PMID: 41549884.

Evidence in colorectal cancer

Colorectal surgery supplies much of the trial evidence. Individual RCTs of multimodal programmes have reported improved functional capacity and, in some studies, fewer severe complications, but other RCTs have not shown a morbidity benefit. Examples include:
  • [RCT . Tier 3 . 2019] Multimodal colorectal prehabilitation trial. PMID: 30670009.
  • [RCT . Tier 3 . 2022] Community exercise prehabilitation for high-risk colorectal surgery patients. PMID: 33443905.
  • [RCT . Tier 3 . 2023] Multimodal prehabilitation before elective colorectal cancer surgery. PMID: 38060453.
  • [RCT . Tier 3 . 2022] Single-centre blinded colorectal RCT reporting no overall morbidity reduction. PMID: 35084526.
A surgical textbook similarly reports lower severe complications and better postoperative functional-capacity measures in studies of laparoscopic or robotic colorectal cancer surgery, while this should not be extrapolated as certainty across all cancer operations. Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice, p. 469.

Practical interpretation

Prehabilitation is most defensible when a patient has modifiable risks such as:
  • low exercise tolerance or deconditioning
  • frailty or sarcopenia risk
  • weight loss, low intake, or malnutrition
  • smoking or hazardous alcohol use
  • anxiety, depression, or low confidence coping with treatment
  • planned major surgery, especially thoracoabdominal surgery
A pragmatic approach is to screen at diagnosis, refer promptly, and tailor intensity to the treatment window and the patient's baseline capacity. Avoid delaying curative therapy solely to complete a fixed-duration programme. For patients with metastatic disease, bone metastases, cardiopulmonary limitations, severe cytopenias, or active treatment-related complications, exercise should be individually prescribed by an appropriately qualified clinician.
Take-home: prehabilitation has its strongest current evidence for improving function and mental-health-related outcomes. Its effect on hard postoperative endpoints remains uncertain, but its low-risk, patient-centred components justify integration into cancer pathways when delivered safely and without delaying indicated treatment.

Find the latest guidelines for cancer prehabilitation

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site:macmillan.org.uk "Prehabilitation for people with cancer" "Clinical and Implementation Guidelines" 2025 PDF

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cancer prehabilitation clinical practice guideline 2025 2026 PDF

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cancer AND prehabilitation

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cancer AND prehabilitation

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https://www.macmillan.org.uk/healthcare-professionals/news-a…

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PMID: 41232938

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PMID: 35576506

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PMID: 40613665

Latest cancer prehabilitation guidelines

The newest broad, cancer-specific guidance I found is:
Macmillan Cancer Support, Prehabilitation for People with Cancer: Clinical and Implementation Guidelines (2025). Launched October 2025, it contains 20 statements and 54 recommendations across 11 areas: early identification and referral, equity, exercise, nutrition, psychological care, behaviour change, digital delivery, implementation, governance, and health economics. It is intended for whole cancer pathways, including non-surgical treatment, not only preoperative care.

Key recommendations from the 2025 Macmillan guidance

  • Start screening and referral as soon as possible after diagnosis.
  • Use a needs-based, personalised multimodal approach:
    • physical activity/exercise
    • nutrition screening and intervention
    • psychological wellbeing support
    • behavioural support, including smoking and alcohol interventions where relevant
  • Embed prehabilitation in routine pathways with multidisciplinary links between oncology, surgery, primary care, rehabilitation, dietetics, psychology, and community/voluntary services.
  • Design services to reduce inequalities in access, acceptance, and adherence.
  • Do not use a fixed programme that delays timely cancer treatment. Match the intervention to the available treatment window and the patient's risks and goals.
Macmillan describes the framework and launch details in its guideline announcement.

Important complementary guidelines

  1. Lung cancer, curative-intent treatment: ERS/ESTS Clinical Practice Guideline (2025)
    This is the most recent specialty guideline relevant to prehabilitation. It recommends structured assessment of fitness for curative treatment, including pulmonary function, exercise testing, cardiac evaluation, comorbidities, and consideration of prehabilitation in selection and optimisation for surgery or other curative treatments. Brunelli et al. (2025), European Respiratory Journal, PMID: 41232938.
  2. Lung cancer functional rehabilitation guideline (2025)
    This guideline supports combined exercise programmes, such as aerobic plus resistance and/or breathing exercise, during the prehabilitation phase to improve mobility and function in people with lung cancer. Vargo et al. (2025), Cancer Medicine, PMID: 40613665.
  3. ASCO Exercise, Diet, and Weight Management During Cancer Treatment Guideline (2022)
    Still the main ASCO guideline relevant to cancer prehabilitation. It recommends regular aerobic and resistance exercise during curative-intent active treatment and states that clinicians may recommend preoperative exercise for lung-cancer surgery, based on evidence of reduced postoperative complications and hospital stay. Ligibel et al. (2022), Journal of Clinical Oncology, PMID: 35576506.
  4. ESPEN Guideline on Clinical Nutrition in Surgery, update 2025
    Relevant where cancer surgery and nutritional risk overlap. It updates perioperative nutrition recommendations and includes frailty assessment, sarcopenia, and nutrition-focused prehabilitation, particularly pertinent to major and upper gastrointestinal cancer surgery. See the ESPEN update record.

Practical hierarchy

  • For a cancer-service pathway or multidisciplinary programme: use the 2025 Macmillan Clinical and Implementation Guidelines as the central operational reference.
  • For lung cancer surgery or curative-intent treatment: add the 2025 ERS/ESTS fitness guideline and the 2025 lung-cancer function guideline.
  • For exercise prescription during active oncology treatment: use the ASCO 2022 guideline.
  • For patients with malnutrition, sarcopenia, or major cancer surgery: add the ESPEN 2025 surgical-nutrition guideline.
A recent caution from the evidence base: the 2026 systematic review in frail patients undergoing cancer surgery found no definitive reduction in length of stay or complications, owing to heterogeneous programmes and studies. Thus guidelines support prehabilitation as tailored optimisation and supportive care, rather than promising uniform reductions in postoperative morbidity. Hoff et al. (2026), PMID: 41549884.

Make a clinical pathway for cancer prehabilitation

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2025 Macmillan cancer prehabilitation clinical implementation guidelines early assessment referral exercise nutrition psychology

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Clinical Pathway: Cancer Prehabilitation

Population: Adults with a new cancer diagnosis who are planned for curative-intent surgery, systemic anticancer therapy, radiotherapy, chemoradiotherapy, transplant, or multimodality treatment.
Aim: Identify and improve modifiable physical, nutritional, psychological, medical, and social risks from diagnosis until treatment begins, without delaying time-sensitive cancer care.

1. Pathway overview

Cancer diagnosis / treatment decision
             ↓
Prehabilitation offer and rapid screening
within 48-72 hours
             ↓
Risk stratification
Low risk / Moderate risk / High or complex risk
             ↓
Personalised multimodal plan and referrals
             ↓
Delivery until treatment starts
with weekly review and escalation if needed
             ↓
Treatment-day handover
             ↓
Continue rehabilitation during and after treatment
Principle: Every eligible patient should be offered prehabilitation, but programme intensity is matched to risk, available treatment window, patient preferences, and safety. Treatment must not be delayed solely to complete prehabilitation.
This pathway follows the 2025 Macmillan framework, which supports early identification, personalised exercise, nutritional and psychological interventions, equity, multidisciplinary working, and integration into routine cancer pathways. See the Macmillan prehabilitation guidance.

2. Step-by-step pathway

Step 1: Trigger and referral

Trigger: Cancer confirmed or strongly suspected, with treatment likely to begin within the next 0 to 12 weeks.
Responsible clinician: Cancer nurse specialist, surgeon, oncologist, MDT coordinator, or preoperative assessment team.

Actions within 48 to 72 hours

  1. Explain prehabilitation and obtain patient agreement.
  2. Record:
    • cancer type, stage, proposed treatment and anticipated start date
    • performance status
    • intent of treatment
    • comorbidities and current medications
    • language, transport, digital access, caregiver support, and financial barriers
  3. Complete the rapid screening bundle below.
  4. Refer according to risk category.

Step 2: Rapid screening bundle

DomainMinimum screenPositive result / concern
Physical functionECOG/WHO performance status; activity history; sit-to-stand or Timed Up and Go where feasibleECOG 2 or above, falls, impaired mobility, low activity, dyspnoea, inability to complete basic function
FrailtyClinical Frailty Scale, G8, or locally validated geriatric screenFrailty, recurrent falls, cognitive concern, polypharmacy, dependence in daily activities
NutritionMUST, PG-SGA short form, or local validated malnutrition screen; weight change and intakeMalnutrition risk, >5% unintentional weight loss over 1 month or >10% over 6 months, poor intake, dysphagia, severe symptoms
Psychological wellbeingDistress thermometer plus problem list, or PHQ-2/GAD-2Moderate-severe distress, depression, anxiety, poor coping, substance misuse, safeguarding concern
Medical optimisationAnaemia, diabetes, cardiopulmonary disease, pain, tobacco/alcohol use, medication reviewUncontrolled comorbidity, symptomatic anaemia, unstable cardiac/respiratory disease, high-risk alcohol use
Social and access needsTransport, finances, language, caring duties, housing, health literacy, digital accessBarriers likely to prevent attendance or adherence

Immediate red flags

Urgent same-day clinical review or emergency pathway if:
  • chest pain, syncope, new significant arrhythmia, or unstable heart failure
  • resting hypoxaemia, acute dyspnoea, suspected pulmonary embolism, or acute infection
  • severe malnutrition with dehydration or inability to maintain oral intake
  • suicidal ideation, acute confusion, safeguarding risk, or severe substance withdrawal risk
  • uncontrolled pain, spinal cord compression symptoms, or suspected pathological fracture.

Step 3: Risk stratification

A. Low risk: universal prehabilitation

Typical profile
  • independently mobile
  • no significant nutritional or psychological risk
  • no major uncontrolled comorbidity
  • short or limited treatment pathway
Management
  • Provide written and verbal education.
  • Encourage daily activity and reduction of prolonged sitting.
  • Provide basic nutrition and symptom-management advice.
  • Offer smoking cessation and alcohol-reduction support.
  • Give contact details for rapid self-referral if symptoms or function worsen.
  • Re-screen at treatment start.

B. Moderate risk: targeted prehabilitation

Typical profile
  • mild functional limitation or reduced activity
  • mild weight loss, reduced intake, fatigue, distress, smoking, or controlled comorbidities
  • planned major surgery or intensive therapy
Management
  • Physiotherapy or exercise professional assessment within 7 days.
  • Dietetic assessment within 7 days if nutritional risk is present.
  • Psychological support, social prescribing, or cancer support service referral.
  • Weekly telephone, virtual, or face-to-face review.
  • Reassess 1 to 2 weeks before treatment, or on the treatment-start date if the interval is short.

C. High or complex risk: multidisciplinary prehabilitation

Typical profile
  • frailty, sarcopenia risk, ECOG 2 or greater, severe deconditioning
  • significant malnutrition or dysphagia
  • high symptom burden
  • major cardiopulmonary disease
  • cognitive impairment, frequent falls, complex social need
  • planned high-risk surgery, including thoracoabdominal or major pelvic surgery
Management
  • Multidisciplinary assessment within 72 hours where feasible.
  • Named prehabilitation coordinator.
  • Physiotherapist/exercise physiologist, dietitian, nurse specialist, medical team, pharmacist, psychology or psychiatry, and geriatrician where indicated.
  • Discuss treatment timing and optimisation plan at MDT or preoperative review.
  • Weekly or twice-weekly contact, adjusted for risk.
  • Handover to anaesthesia, surgical, oncology, and inpatient rehabilitation teams before treatment.

3. Core intervention package

A. Exercise and functional optimisation

Assessment
  • Baseline function: 30-second sit-to-stand, 6-minute walk test, Timed Up and Go, grip strength, or a locally standardised alternative.
  • Falls risk, pain, neuropathy, bone health, cardiorespiratory symptoms, and contraindications.
Prescription
  • Individualise frequency, intensity, time, and type.
  • Combine:
    • aerobic activity
    • progressive resistance exercise
    • mobility and balance work
    • breathing or inspiratory muscle training where indicated, especially for thoracic surgery or lung cancer.
Safety modifications
  • Obtain specialist advice for unstable bone metastases, severe thrombocytopenia, febrile illness, uncontrolled pain, cardiopulmonary instability, or high fracture risk.
  • Avoid unsupervised high-impact exercise in patients with unstable skeletal disease.
For lung cancer, 2025 guidance supports combined aerobic, resistance, and/or breathing exercise to improve mobility during prehabilitation. Vargo et al. (2025), Cancer Medicine, PMID: 40613665.

B. Nutrition optimisation

Actions
  • Dietitian referral for all patients at nutritional risk.
  • Address intake-limiting symptoms: nausea, dysphagia, odynophagia, constipation, diarrhoea, mucositis, early satiety, pain, and altered taste.
  • Aim for adequate energy and protein intake, adjusted for renal, hepatic, metabolic, and treatment-specific factors.
  • Consider oral nutritional supplements when food-first measures are insufficient.
  • Escalate promptly for enteral or parenteral nutrition assessment when oral intake is inadequate or unsafe.
Record
  • weight, percentage weight loss, intake adequacy, nutrition risk score, and agreed nutrition goals.

C. Psychological and behavioural support

Actions
  • Provide clear information about diagnosis, treatment, symptoms, exercise, nutrition, and recovery.
  • Offer brief interventions for anxiety, sleep, distress, and coping.
  • Refer to psychology or psychiatry for moderate-severe distress, clinical depression/anxiety, trauma, severe insomnia, substance dependence, or suicide risk.
  • Offer smoking cessation and alcohol reduction support.
  • Incorporate patient-defined goals and caregiver support.

D. Medical optimisation

Review and manage
  • anaemia and iron deficiency
  • diabetes and peri-treatment glycaemic plan
  • hypertension, ischaemic heart disease, heart failure, and arrhythmias
  • COPD, asthma, obstructive sleep apnoea, and pulmonary rehabilitation needs
  • medication reconciliation, including anticoagulants, steroids, opioids, and sedatives
  • pain control
  • vaccination and infection-risk measures where relevant
  • frailty, falls, cognition, continence, and polypharmacy.

E. Social, practical, and equity support

Assess and document barriers. Offer:
  • community exercise options, supervised programmes, or home-based alternatives
  • transport and parking support
  • interpreter or translated resources
  • telephone rather than digital-only delivery when needed
  • welfare, employment, housing, and benefits advice
  • caregiver engagement, peer support, and voluntary-sector referral.

4. Treatment-window model

Time available before treatmentRecommended approach
0 to 7 daysRapid assessment, safety-netting, nutrition and symptom management, brief exercise advice, smoking/alcohol intervention, and treatment-day handover. Do not delay urgent therapy.
1 to 4 weeksTargeted or multimodal plan, supervised or home-based exercise, dietetic and psychological input, weekly review.
More than 4 weeksFull personalised multimodal programme, formal baseline and repeat functional testing, goal progression, and a documented treatment-readiness review.

5. Review and escalation

Weekly review checklist

  • Treatment date confirmed or changed?
  • Attendance and adherence barriers?
  • New symptoms, falls, pain, dyspnoea, infection, or weight loss?
  • Exercise tolerance and functional progress?
  • Nutrition intake and weight trend?
  • Distress, sleep, smoking, alcohol, and support needs?
  • Need to increase, decrease, pause, or redirect intervention?

Escalate to MDT or treating clinician if

  • functional decline despite intervention
  • continued clinically important weight loss or inadequate intake
  • worsening frailty or falls
  • unresolved psychological distress
  • new cardiopulmonary symptoms
  • treatment tolerance concerns
  • social barriers likely to cause treatment interruption.

6. Treatment-day handover

Provide a concise documented summary to the surgical, anaesthetic, radiotherapy, or systemic-treatment team:
  1. Baseline risk category and functional status.
  2. Frailty and fall-risk findings.
  3. Nutrition risk, weight trend, current plan, and feeding requirements.
  4. Exercise plan and restrictions.
  5. Psychological, social, and communication needs.
  6. Smoking, alcohol, and medication considerations.
  7. Outstanding referrals and escalation plan.
  8. Post-treatment rehabilitation plan.

7. Post-treatment transition

Prehabilitation should transition directly into rehabilitation.
At treatment start
  • confirm a contact person
  • avoid loss of exercise/nutrition support unless clinically necessary
  • modify the plan for treatment toxicity, fatigue, cytopenias, pain, and changing function.
After surgery or completion of radical treatment
  • reassess function, nutrition, distress, and social needs
  • continue rehabilitation until recovery plateaus or self-management is established
  • refer to survivorship, community rehabilitation, or specialist services as needed.

8. Minimum dataset and service metrics

Patient-level measures

  • time from diagnosis to screening
  • time from screening to first prehabilitation contact
  • risk category
  • completion and adherence rate
  • weight and nutrition-risk score
  • functional test results at baseline and treatment start
  • distress score
  • smoking status
  • treatment delays attributable to modifiable factors
  • postoperative complications, length of stay, treatment completion, and patient-reported outcomes where applicable.

Suggested service standards

  • Screening offered within 72 hours of diagnosis or treatment decision
  • High-risk referral initiated within 72 hours
  • Moderate-risk assessment within 7 days
  • Documented handover before treatment for all high-risk patients
  • Equity monitoring by deprivation, ethnicity, language, rurality, disability, age, and digital access.

Evidence note

The pathway prioritises function, nutritional status, wellbeing, and readiness for treatment. It should not guarantee lower complication rates for every patient. Recent systematic reviews find meaningful heterogeneity in programme design and clinical outcomes, especially among frail surgical patients. Hoff et al. (2026), Internal Medicine Journal, PMID: 41549884. This supports individualised, risk-based delivery rather than a single mandatory programme for all patients.

Can you please make a PowerPoint of the same

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mkdir -p "/tmp/workspace/cancer-prehabilitation-ppt/src" "/tmp/workspace/cancer-prehabilitation-ppt/output" && printf '%s' 'workspace prepared'

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cat > "/tmp/workspace/cancer-prehabilitation-ppt/src/create_deck.py" <<'PY' from pptx import Presentation from pptx.util import Inches, Pt from pptx.dml.color import RGBColor from pptx.enum.text import PP_ALIGN, MSO_ANCHOR from pptx.enum.shapes import MSO_SHAPE, MSO_CONNECTOR from pptx.enum.dml import MSO_THEME_COLOR from pptx.enum.text import MSO_AUTO_SIZE OUT = '/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway.pptx' prs = Presentation() prs.slide_width = Inches(13.333) prs.slide_height = Inches(7.5) blank = prs.slide_layouts[6] # Palette NAVY = RGBColor(16, 49, 76) TEAL = RGBColor(0, 132, 139) MINT = RGBColor(220, 241, 236) SKY = RGBColor(229, 241, 247) GOLD = RGBColor(237, 177, 75) CORAL = RGBColor(205, 94, 76) INK = RGBColor(30, 45, 58) MUTED = RGBColor(91, 111, 125) LIGHT = RGBColor(246, 249, 250) WHITE = RGBColor(255,255,255) LINE = RGBColor(205,218,223) def rect(slide, x,y,w,h, fill, line=None, radius=False): shp=slide.shapes.add_shape(MSO_SHAPE.ROUNDED_RECTANGLE if radius else MSO_SHAPE.RECTANGLE, Inches(x), Inches(y), Inches(w), Inches(h)) shp.fill.solid(); shp.fill.fore_color.rgb=fill shp.line.color.rgb = line if line else fill if radius: shp.adjustments[0]=0.08 return shp def text(slide, x,y,w,h, value, size=18, color=INK, bold=False, align=PP_ALIGN.LEFT, font='Aptos', valign=MSO_ANCHOR.TOP, margin=0.06): tb=slide.shapes.add_textbox(Inches(x), Inches(y), Inches(w), Inches(h)) tf=tb.text_frame; tf.clear(); tf.word_wrap=True; tf.vertical_anchor=valign tf.margin_left=tf.margin_right=Inches(margin); tf.margin_top=tf.margin_bottom=Inches(margin) p=tf.paragraphs[0]; p.alignment=align r=p.add_run(); r.text=value; r.font.name=font; r.font.size=Pt(size); r.font.bold=bold; r.font.color.rgb=color return tb def add_bullets(slide,x,y,w,h,items,size=18,color=INK,bullet_color=TEAL,leading=1.18): tb=slide.shapes.add_textbox(Inches(x), Inches(y), Inches(w), Inches(h)); tf=tb.text_frame; tf.clear(); tf.word_wrap=True tf.margin_left=Inches(.03);tf.margin_right=Inches(.03);tf.margin_top=Inches(.02);tf.margin_bottom=Inches(.02) for i,item in enumerate(items): p=tf.paragraphs[0] if i==0 else tf.add_paragraph(); p.text=item; p.level=0; p.font.name='Aptos';p.font.size=Pt(size);p.font.color.rgb=color p.space_after=Pt(8); p.bullet=True return tb def title(slide, title_text, kicker=None, num=None): rect(slide,0,0,13.333,.18,TEAL) if kicker: text(slide,.58,.38,11.7,.28,kicker.upper(),10,TEAL,True) text(slide,.56,.68,11.7,.52,title_text,28,NAVY,True) rect(slide,.56,1.30,1.05,.05,GOLD) if num: text(slide,12.25,.45,.48,.30,num,10,MUTED,True,PP_ALIGN.RIGHT) def footer(slide, source='Clinical pathway draft | October 2026'): rect(slide,.56,7.10,12.2,.012,LINE) text(slide,.56,7.16,8.5,.18,source,8.5,MUTED) text(slide,11.75,7.16,1.0,.18,'Cancer prehabilitation',8.5,MUTED,False,PP_ALIGN.RIGHT) def arrow(slide,x1,y1,x2,y2,color=TEAL,width=2): ln=slide.shapes.add_connector(MSO_CONNECTOR.STRAIGHT, Inches(x1), Inches(y1), Inches(x2), Inches(y2)) ln.line.color.rgb=color; ln.line.width=Pt(width) ln.line.end_arrowhead = True return ln def pill(slide,x,y,w,label,fill=SKY,fg=NAVY): rect(slide,x,y,w,.34,fill,fill,True); text(slide,x+.06,y+.05,w-.12,.21,label,10,fg,True,PP_ALIGN.CENTER) # 1 Title s=prs.slides.add_slide(blank) rect(s,0,0,13.333,7.5,NAVY) rect(s,0,0,13.333,.18,TEAL) # design circles for x,y,r,c in [(10.8,.9,1.7,TEAL),(11.55,1.65,.85,GOLD),(9.9,5.55,1.25,RGBColor(25,72,104))]: sh=s.shapes.add_shape(MSO_SHAPE.OVAL,Inches(x),Inches(y),Inches(r),Inches(r)); sh.fill.solid();sh.fill.fore_color.rgb=c;sh.line.color.rgb=c text(s,.72,1.05,8.8,.34,'CLINICAL PATHWAY',14,RGBColor(158,222,217),True) text(s,.68,1.52,8.6,1.55,'Cancer\nprehabilitation',38,WHITE,True) text(s,.72,3.38,7.6,.8,'A needs-based, multimodal pathway from diagnosis to treatment and rehabilitation',18,RGBColor(221,235,239)) rect(s,.72,5.35,3.05,.48,TEAL,TEAL,True);text(s,.83,5.46,2.82,.22,'Adult cancer pathways',12,WHITE,True,PP_ALIGN.CENTER) text(s,.72,6.72,5,.25,'Prepared for clinical pathway development | October 2026',10,RGBColor(187,208,215)) # 2 purpose s=prs.slides.add_slide(blank); title(s,'Purpose, scope and operating principles','Pathway at a glance','02') text(s,.62,1.58,5.75,.55,'Who is this for?',20,NAVY,True) add_bullets(s,.65,2.18,5.7,2.8,[ 'Adults with a new cancer diagnosis and planned curative-intent treatment', 'Surgery, systemic therapy, radiotherapy, chemoradiotherapy, transplant, or multimodality care', 'Begins at diagnosis or treatment decision, then transitions into rehabilitation' ],17) rect(s,6.73,1.55,5.85,4.6,SKY,SKY,True) text(s,7.05,1.88,5.2,.40,'Operating principles',20,NAVY,True) principles=[('Start early','Screen and refer as soon as possible after diagnosis.'),('Tailor care','Match intensity to risk, treatment window and patient goals.'),('Do not delay therapy','Prehabilitation supports, but does not postpone, time-sensitive treatment.'),('Design for access','Address transport, language, cost, digital and caregiver barriers.')] for i,(a,b) in enumerate(principles): y=2.50+i*.79 rect(s,7.07,y,.33,.33,TEAL,TEAL,True); text(s,7.16,y+.065,.15,.16,str(i+1),10,WHITE,True,PP_ALIGN.CENTER) text(s,7.55,y-.02,2.1,.24,a,13,NAVY,True); text(s,7.55,y+.24,4.53,.28,b,11.5,INK) footer(s) # 3 Pathway map s=prs.slides.add_slide(blank); title(s,'End-to-end pathway','One route, three levels of support','03') steps=[('1','Diagnosis / treatment decision','Offer prehabilitation'),('2','Rapid screen','Within 48-72 h'),('3','Risk stratify','Low | moderate | high'),('4','Personalised plan','Core domains + referrals'),('5','Review & handover','Weekly review; treatment-ready summary'),('6','Rehabilitation','Continue during and after treatment')] for i,(n,a,b) in enumerate(steps): x=.62+i*2.08 rect(s,x,2.08,1.72,1.72,WHITE,LINE,True) rect(s,x+.12,2.22,.36,.36,TEAL,TEAL,True);text(s,x+.19,2.295,.2,.13,n,9,WHITE,True,PP_ALIGN.CENTER) text(s,x+.16,2.76,1.40,.48,a,13,NAVY,True,PP_ALIGN.CENTER) text(s,x+.14,3.32,1.44,.28,b,10.5,MUTED,False,PP_ALIGN.CENTER) if i<5: arrow(s,x+1.74,2.94,x+2.00,2.94,TEAL,1.8) text(s,.68,4.55,12,.32,'The pathway is cyclical: changing symptoms, treatment dates or risks trigger reassessment and plan adjustment.',16,INK,False,PP_ALIGN.CENTER) rect(s,1.3,5.35,10.75,.68,MINT,MINT,True);text(s,1.58,5.56,10.15,.25,'Safety rule: urgent medical, nutritional or psychological concerns bypass routine prehabilitation and enter the appropriate clinical escalation pathway.',13,NAVY,True,PP_ALIGN.CENTER) footer(s) #4 rapid screen s=prs.slides.add_slide(blank); title(s,'Rapid screening bundle','Complete within 48-72 hours','04') domains=[('Physical function','Performance status, activity, mobility, falls, dyspnoea'),('Frailty','Clinical Frailty Scale, G8 or local validated screen'),('Nutrition','Weight loss, oral intake, MUST / PG-SGA Short Form'),('Psychological','Distress screen, anxiety, mood, coping, sleep'),('Medical','Anaemia, comorbidity, medicines, pain, tobacco/alcohol'),('Social access','Transport, language, finances, caregiving, digital access')] for i,(a,b) in enumerate(domains): col=i%2; row=i//2; x=.65+col*6.15; y=1.62+row*1.47 rect(s,x,y,5.65,1.15, LIGHT,LINE,True) rect(s,x+.18,y+.19,.36,.36,[TEAL,GOLD,CORAL][row%3],[TEAL,GOLD,CORAL][row%3],True) text(s,x+.67,y+.16,4.58,.26,a,15,NAVY,True);text(s,x+.67,y+.51,4.65,.38,b,12,INK) rect(s,.65,6.12,12.0,.52,SKY,SKY,True); text(s,.88,6.28,11.5,.17,'Document treatment intent and anticipated start date at the same encounter. This determines the achievable prehabilitation dose.',11.5,NAVY,True,PP_ALIGN.CENTER) footer(s) #5 Red flags s=prs.slides.add_slide(blank);title(s,'Red flags and immediate escalation','Do not wait for routine prehabilitation review','05') rect(s,.64,1.55,12.05,.62,RGBColor(250,231,227),RGBColor(250,231,227),True);text(s,.90,1.75,11.55,.20,'Escalate the same day to the treating team, acute service, nutrition team or mental-health pathway according to local policy.',13,CORAL,True,PP_ALIGN.CENTER) flags=[('Acute medical','Chest pain, syncope, significant arrhythmia, acute dyspnoea, resting hypoxaemia, infection'),('Severe nutrition risk','Dehydration, inability to maintain oral intake, rapidly progressive weight loss, unsafe swallow'),('Psychological / safeguarding','Suicidal ideation, acute confusion, safeguarding concern, severe withdrawal risk'),('Cancer-related emergency','Uncontrolled pain, neurological deficit, spinal cord compression symptoms, suspected pathological fracture')] for i,(a,b) in enumerate(flags): x=.80+(i%2)*6.0;y=2.65+(i//2)*1.55 rect(s,x,y,5.52,1.20,WHITE,LINE,True); rect(s,x+.18,y+.21,.34,.34,CORAL,CORAL,True) text(s,x+.66,y+.17,4.45,.25,a,15,NAVY,True);text(s,x+.66,y+.52,4.45,.43,b,11.5,INK) text(s,.70,6.03,11.9,.42,'Always use local emergency, deterioration and safeguarding policies. This slide does not replace assessment by an appropriately qualified clinician.',11.5,MUTED,False,PP_ALIGN.CENTER) footer(s) # 6 stratification s=prs.slides.add_slide(blank);title(s,'Risk stratification and service response','Risk determines contact intensity, not eligibility','06') levels=[('LOW','Universal support','Independent mobility; no major nutritional, psychological or medical risk','Education, self-management plan, lifestyle support, re-screen at treatment start',MINT,TEAL),('MODERATE','Targeted support','Mild functional limitation, nutrition risk, distress, smoking or controlled comorbidity','Physio/exercise and relevant dietetic or wellbeing review within 7 days; weekly follow-up',SKY,NAVY),('HIGH / COMPLEX','Multidisciplinary plan','Frailty, major deconditioning, significant malnutrition, high symptom burden or complex social need','Assessment within 72 h where feasible; named coordinator; documented treatment handover',RGBColor(250,237,224),CORAL)] for i,(head,sub,criteria,act,bg,accent) in enumerate(levels): x=.62+i*4.16 rect(s,x,1.65,3.78,4.93,bg,bg,True);rect(s,x,1.65,3.78,.56,accent,accent,True) text(s,x+.19,1.82,3.38,.18,head,13,WHITE,True,PP_ALIGN.CENTER) text(s,x+.23,2.47,3.30,.36,sub,18,NAVY,True,PP_ALIGN.CENTER) text(s,x+.25,3.12,3.25,.22,'Typical profile',11,MUTED,True,PP_ALIGN.CENTER) text(s,x+.25,3.42,3.25,.95,criteria,12,INK,False,PP_ALIGN.CENTER) rect(s,x+.30,4.67,3.18,.02,accent,accent) text(s,x+.25,4.89,3.25,.22,'Service response',11,MUTED,True,PP_ALIGN.CENTER) text(s,x+.25,5.20,3.25,.87,act,12,INK,False,PP_ALIGN.CENTER) footer(s) #7 core intervention s=prs.slides.add_slide(blank);title(s,'Personalised multimodal intervention','Build the plan around patient goals and treatment readiness','07') core=[('Exercise & function','Aerobic, resistance, mobility, balance; breathing training when indicated',TEAL),('Nutrition','Screening, symptom management, food-first advice, supplements and feeding escalation when needed',GOLD),('Psychological & behavioural','Information, distress support, sleep, coping, smoking and alcohol intervention',CORAL),('Medical optimisation','Anaemia, comorbidity, medication, pain, diabetes, respiratory and cardiac optimisation',NAVY),('Social & practical support','Transport, language, finances, carer support, community and digital options',RGBColor(92,151,176))] for i,(a,b,c) in enumerate(core): x=.65+(i%3)*4.12;y=1.65+(i//3)*2.18 rect(s,x,y,3.74,1.73,WHITE,LINE,True);rect(s,x+.20,y+.20,.42,.42,c,c,True) text(s,x+.73,y+.18,2.75,.28,a,14,NAVY,True);text(s,x+.23,y+.80,3.24,.64,b,11.5,INK) # sixth conceptual card x=.65+2*4.12;y=3.83 rect(s,x,y,3.74,1.73,MINT,MINT,True);text(s,x+.28,y+.23,3.17,.24,'Care coordination',14,NAVY,True,PP_ALIGN.CENTER);text(s,x+.30,y+.74,3.12,.58,'Named contact, shared record, MDT links and treatment-day handover.',11.5,INK,False,PP_ALIGN.CENTER) text(s,.70,6.33,11.9,.24,'Select only interventions that are clinically appropriate, feasible in the available treatment window and acceptable to the patient.',12,NAVY,True,PP_ALIGN.CENTER) footer(s) #8 Time window s=prs.slides.add_slide(blank);title(s,'Match the plan to the treatment window','Treatment timing shapes the achievable dose','08') windows=[('0-7 days','Rapid optimisation','Safety-netting; symptom and nutrition support; brief activity advice; treatment-day handover',CORAL),('1-4 weeks','Targeted programme','Supervised or home-based exercise; dietetic and wellbeing input; weekly review',GOLD),('>4 weeks','Full multimodal programme','Baseline and repeat function testing; progressive goals; formal treatment-readiness review',TEAL)] for i,(a,b,c,d) in enumerate(windows): x=.78+i*4.13 rect(s,x,1.77,3.63,3.96,WHITE,LINE,True);rect(s,x,1.77,3.63,.70,d,d,True) text(s,x+.18,1.98,3.28,.22,a,16,WHITE,True,PP_ALIGN.CENTER) text(s,x+.25,2.80,3.15,.40,b,18,NAVY,True,PP_ALIGN.CENTER) text(s,x+.30,3.50,3.02,1.05,c,13,INK,False,PP_ALIGN.CENTER) rect(s,x+.55,5.06,2.5,.28,RGBColor(238,246,246),RGBColor(238,246,246),True);text(s,x+.64,5.12,2.32,.15,'Do not postpone urgent therapy',9.5,NAVY,True,PP_ALIGN.CENTER) text(s,.78,6.25,11.75,.24,'If treatment dates change, reassess risk and redesign the plan instead of restarting the pathway.',12,MUTED,False,PP_ALIGN.CENTER) footer(s) #9 review handover s=prs.slides.add_slide(blank);title(s,'Review, escalation and treatment-day handover','Close the loop before treatment begins','09') rect(s,.63,1.62,5.75,4.72,SKY,SKY,True);text(s,.95,1.95,5.0,.30,'Weekly review checklist',20,NAVY,True) add_bullets(s,.97,2.58,5.05,3.1,[ 'Treatment date confirmed or changed?', 'Attendance, adherence and access barriers?', 'New symptoms, falls, pain, dyspnoea, infection or weight loss?', 'Function, intake, distress and goals improving?', 'Does the plan need escalation, reduction or pause?' ],14.5) rect(s,6.76,1.62,5.90,4.72,MINT,MINT,True);text(s,7.08,1.95,5.22,.30,'Treatment-day handover',20,NAVY,True) add_bullets(s,7.10,2.58,5.16,3.4,[ 'Baseline risk, function, frailty and falls assessment', 'Nutrition status, weight trend and feeding plan', 'Exercise plan, restrictions and safety considerations', 'Psychological, communication and social support needs', 'Medication, smoking/alcohol and unresolved risks', 'Post-treatment rehabilitation plan and named contact' ],14.2) footer(s) #10 measurement s=prs.slides.add_slide(blank);title(s,'Minimum dataset and quality measures','Use data to improve reach, safety and outcomes','10') cols=[('Timeliness',['Diagnosis to screen','Screen to first contact','High-risk response within 72 h']),('Reach & equity',['Offer, uptake and completion','Language, deprivation, rurality, ethnicity, disability','Digital and travel barriers']),('Patient change',['Function and activity','Weight / nutrition-risk score','Distress and patient goals']),('Treatment outcomes',['Readiness at treatment start','Treatment completion / interruptions','Complications, length of stay, patient-reported outcomes'])] for i,(a,items) in enumerate(cols): x=.55+i*3.17; rect(s,x,1.78,2.86,4.44,WHITE,LINE,True);rect(s,x,1.78,2.86,.58,[TEAL,NAVY,GOLD,CORAL][i],[TEAL,NAVY,GOLD,CORAL][i],True) text(s,x+.15,1.96,2.55,.20,a,14,WHITE,True,PP_ALIGN.CENTER) add_bullets(s,x+.22,2.72,2.42,2.86,items,13.5) text(s,.70,6.48,11.95,.22,'Review measures by tumour group and by equity strata. Use results for service improvement, not as a reason to withhold support.',11.5,NAVY,True,PP_ALIGN.CENTER) footer(s) #11 governance s=prs.slides.add_slide(blank);title(s,'Implementation checklist','Make the pathway usable in routine care','11') items=[('Governance','Executive sponsor, clinical lead, pathway owner and escalation policy'),('Workforce','Named coordinator plus defined access to exercise, nutrition, psychological and medical support'),('Workflow','Referral trigger embedded in MDT, clinic or pre-assessment; shared documentation template'),('Access','In-person, community, telephone and digital options with proactive equity adaptation'),('Training','Brief education for referrers on screening, red flags, safety and expectations'),('Co-production','Develop materials and service design with people living with cancer and carers')] for i,(a,b) in enumerate(items): x=.65+(i%2)*6.05;y=1.55+(i//2)*1.55 rect(s,x,y,5.55,1.18,LIGHT,LINE,True);rect(s,x+.20,y+.23,.38,.38,TEAL,TEAL,True);text(s,x+.32,y+.30,.14,.13,'✓',10,WHITE,True,PP_ALIGN.CENTER) text(s,x+.75,y+.17,4.45,.23,a,14,NAVY,True);text(s,x+.75,y+.51,4.40,.34,b,11.5,INK) footer(s) #12 citations s=prs.slides.add_slide(blank);title(s,'Evidence base and source documents','Use local policy and specialty guidance alongside this pathway','12') refs=[ 'Macmillan Cancer Support. Prehabilitation for People with Cancer: Clinical and Implementation Guidelines. 2025. Available via Macmillan professional prehabilitation resources.', 'Brunelli A, et al. European Respiratory Society and European Society of Thoracic Surgeons clinical practice guideline on fitness for curative intent treatment of lung cancer. Eur Respir J. 2025. PMID: 41232938.', 'Vargo M, et al. Recommendations for interventions to improve function in patients with lung cancer: a clinical practice guideline. Cancer Medicine. 2025. PMID: 40613665.', 'Ligibel JA, et al. Exercise, diet, and weight management during cancer treatment: ASCO guideline. J Clin Oncol. 2022. PMID: 35576506.', 'Hoff JL, et al. Prehabilitation in patients with frailty undergoing cancer-related surgery: a systematic review. Intern Med J. 2026. PMID: 41549884.' ] text(s,.67,1.54,12.0,.30,'Key message',18,NAVY,True) rect(s,.67,1.95,12.0,.78,MINT,MINT,True);text(s,.95,2.17,11.48,.31,'Prehabilitation improves readiness and can support function, nutrition and wellbeing. Expected benefits and clinical endpoints vary across cancer populations, so use an individualised, risk-based approach.',13,NAVY,True,PP_ALIGN.CENTER) text(s,.67,3.12,12,.27,'References',18,NAVY,True) add_bullets(s,.75,3.55,11.8,2.75,refs,11.2,INK) text(s,.72,6.60,11.8,.22,'Clinical disclaimer: This presentation is an implementation aid, not a substitute for local governance, specialist review or individual clinical judgement.',10.5,MUTED,False,PP_ALIGN.CENTER) footer(s,'Sources current to October 2026') prs.save(OUT) print(OUT) PY python "/tmp/workspace/cancer-prehabilitation-ppt/src/create_deck.py"

Running Command

python - <<'PY' from pptx import Presentation p='/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway.pptx' prs=Presentation(p) print('slides', len(prs.slides)) for i,s in enumerate(prs.slides,1): texts=[sh.text_frame.text.replace('\n',' | ') for sh in s.shapes if sh.has_text_frame and sh.text_frame.text.strip()] print(i, texts[0][:85] if texts else 'NO TEXT', 'shapes',len(s.shapes)) PY python - <<'PY' from zipfile import ZipFile p='/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway.pptx' with ZipFile(p) as z: bad=z.testzip() print('zip_integrity', 'OK' if bad is None else bad) PY ls -lh "/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway.pptx"

Created a 12-slide clinical PowerPoint covering:
  • Purpose, scope, and guiding principles
  • End-to-end referral and triage pathway
  • Screening and red-flag escalation
  • Low, moderate, and high-risk care streams
  • Multimodal intervention components
  • Treatment-window planning
  • Review, handover, quality metrics, implementation, and references

Cancer Prehabilitation Clinical Pathway

Presentation · PPTX

Add speaker notes and presenter guidance

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~/

Searching the Web

Macmillan 2025 cancer prehabilitation clinical implementation guidance early assessment referral exercise nutrition psychology

Searching PubMed

cancer AND prehabilitation

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~/cancer-prehabilitation-ppt/

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Running Command

python - <<'PY' from pptx import Presentation p='/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway.pptx' prs=Presentation(p) s=prs.slides[0] print('has notes_slide', hasattr(s,'notes_slide')) if hasattr(s,'notes_slide'): print(s.notes_slide) print([(sh.name,sh.has_text_frame, getattr(sh.text_frame,'text','') if sh.has_text_frame else '') for sh in s.notes_slide.shapes]) PY

Running Command

cat > "/tmp/workspace/cancer-prehabilitation-ppt/src/add_notes.py" <<'PY' from pptx import Presentation SOURCE = '/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway.pptx' OUT = '/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway_with_Speaker_Notes.pptx' notes = [ """PRESENTER GUIDANCE Timing: 45-60 seconds. Audience: clinical leaders and pathway stakeholders. SAY: "This presentation sets out a practical clinical pathway for cancer prehabilitation. It is intended to help teams move from an ad hoc referral model to a consistent, needs-based service from diagnosis through treatment and into rehabilitation." EMPHASISE: Prehabilitation is not a separate elective programme. It is part of treatment readiness and supportive cancer care. TRANSITION: "First, let us define who the pathway is for and the principles that keep it safe and workable.""", """PRESENTER GUIDANCE Timing: 60-75 seconds. SAY: "The pathway applies to adults starting curative-intent cancer treatment, not only those having surgery. Its purpose is to identify modifiable risks early and provide the right intensity of support in the available window before treatment." EMPHASISE: The principles are early action, tailoring to individual need, protection of treatment timelines, and equitable access. Do not present this as a fixed-duration programme that every patient must complete. ASK THE AUDIENCE: "Which treatment pathways in our service currently offer the earliest practical referral point?" TRANSITION: "These principles translate into a simple six-step operational pathway.""", """PRESENTER GUIDANCE Timing: 60 seconds. SAY: "This is the whole pathway in one view. We begin when diagnosis or a treatment decision is made, screen rapidly, stratify risk, provide a tailored plan, review progress and hand over clearly at treatment start. Support then continues as rehabilitation." EMPHASISE: This is a loop rather than a one-off event. A changed treatment date, new symptom, or loss of function should trigger reassessment. PAUSE on the safety rule: urgent clinical problems leave the routine pathway and use established escalation routes. TRANSITION: "The first operational task is a short, reliable screening bundle.""", """PRESENTER GUIDANCE Timing: 75-90 seconds. SAY: "The screening bundle is deliberately broad. A patient may be fit enough to exercise but have nutrition risk, high distress, uncontrolled pain, or barriers that make attendance impossible. Each of these can affect treatment readiness." EMPHASISE: Record the expected treatment start date at the same encounter. It determines whether the team can offer rapid optimisation, a targeted programme, or a fuller multimodal plan. IMPLEMENTATION TIP: Build the screen into an existing MDT, diagnostic clinic, oncology clinic, or pre-assessment workflow rather than creating a parallel referral process. TRANSITION: "Screening must also identify the small group who need action today.""", """PRESENTER GUIDANCE Timing: 60 seconds. SAY: "Prehabilitation must never create delay in recognition or management of acute deterioration. These examples are prompts for immediate escalation using local policy, not a complete emergency checklist." EMPHASISE: Severe intake failure, acute cardiopulmonary symptoms, safeguarding concerns, and cancer emergencies should be managed by the appropriate urgent service. The prehabilitation team should communicate, coordinate and resume support when clinically appropriate. CAUTION: Do not advise audiences to use this slide for independent triage. Local emergency pathways take precedence. TRANSITION: "For patients without red flags, we stratify intensity of support.""", """PRESENTER GUIDANCE Timing: 75 seconds. SAY: "Everyone can receive an offer of basic support. Risk stratification determines the speed, intensity and team composition, not who deserves access." LOW RISK: Education, self-management and re-screening may be enough. MODERATE RISK: Add targeted exercise, dietetic, wellbeing or behaviour support, usually with weekly contact. HIGH OR COMPLEX RISK: Bring in a multidisciplinary plan quickly, nominate a coordinator, and document the treatment handover. EMPHASISE: Use locally approved assessment tools. Do not treat this slide as a diagnostic definition of frailty or malnutrition. TRANSITION: "The care plan is multimodal because risk is rarely confined to one domain.""", """PRESENTER GUIDANCE Timing: 75-90 seconds. SAY: "The intervention is selected with the patient, based on their goals, symptoms, fitness, safety considerations and treatment window. The core domains are exercise and function, nutrition, psychological and behavioural support, medical optimisation, and practical access support." EMPHASISE: Avoid automatic exercise prescriptions. For example, patients with unstable skeletal disease, severe cytopenia, acute infection, high fracture risk, or cardiopulmonary instability need individual clinical assessment and modification. IMPLEMENTATION TIP: A named coordinator and shared record prevent fragmented referrals from becoming a burden for patients. TRANSITION: "The time available before treatment determines the dose we can realistically deliver.""", """PRESENTER GUIDANCE Timing: 60 seconds. SAY: "Short windows still matter. In the first week, the priority is safety, symptom control, nutrition, brief activity advice and a clear handover. A one-to-four-week window can support targeted exercise and dietetic or psychological work. Longer windows permit progressive goals and repeat measures." EMPHASISE: The clinical team should redesign the plan when the date changes, rather than automatically delaying treatment to finish a programme. TRANSITION: "We then review progress and make treatment readiness visible to the treating team.""", """PRESENTER GUIDANCE Timing: 75 seconds. SAY: "Weekly review is a practical minimum for moderate and high-risk patients, adjusted to clinical need. It should check treatment timing, engagement barriers, new symptoms, function, intake and distress." EMPHASISE: The treatment-day handover is the safety net. It gives the surgical, anaesthetic, radiotherapy or systemic-treatment team a concise account of risk, restrictions, nutrition plan, psychosocial needs and the plan after treatment begins. IMPLEMENTATION TIP: Use a single structured handover template in the electronic record where possible. TRANSITION: "To sustain the service, we need measures that assess more than hospital outcomes.""", """PRESENTER GUIDANCE Timing: 60 seconds. SAY: "Measure whether the service reaches people quickly and fairly, whether patients experience meaningful change, and whether care is carried through to treatment." EMPHASISE: Completion rate alone can be misleading. Review uptake and outcomes by deprivation, ethnicity, disability, language, rurality and digital access. This helps identify whether the model unintentionally excludes people. CAUTION: Use outcomes for quality improvement rather than as a gatekeeping mechanism for access to treatment or support. TRANSITION: "The final operational question is how to make this routine rather than dependent on individual champions.""", """PRESENTER GUIDANCE Timing: 60-75 seconds. SAY: "Implementation needs ownership, workforce routes, an embedded workflow, multiple modes of access, staff training and co-production with people living with cancer." EMPHASISE: Start with one or two tumour pathways if necessary, but build the data and governance structure so that expansion is possible. Community, primary-care and voluntary-sector partnerships can increase capacity and reach. ASK THE AUDIENCE: "Who would be the executive sponsor, clinical lead and pathway owner in our setting?" TRANSITION: "These recommendations align with current cancer prehabilitation and specialty guidance.""", """PRESENTER GUIDANCE Timing: 45-60 seconds. SAY: "The pathway is informed by the 2025 Macmillan clinical and implementation guidance and complementary specialty guidance. The evidence supports improving readiness, function, nutrition and wellbeing, but effect sizes and postoperative endpoints differ across cancer groups and programmes." EMPHASISE: Local policy, specialty-specific guidance, and individual clinical judgement remain essential. The pathway should be adapted through local governance rather than copied without review. CLOSE: "The next step is to agree the first pilot pathway, referral trigger, minimum dataset and accountable leads." REFERENCES: Full sources are listed on this slide; retain them when adapting the deck.""" ] prs=Presentation(SOURCE) assert len(prs.slides)==len(notes) for slide, note_text in zip(prs.slides, notes): ns=slide.notes_slide target=None for shape in ns.shapes: if shape.has_text_frame and 'Notes Placeholder' in shape.name: target=shape break if target is None: for shape in ns.shapes: if shape.has_text_frame: target=shape break tf=target.text_frame tf.clear() # Preserve clear headings and paragraphs in PowerPoint notes pane for idx, para in enumerate(note_text.split('\n')): p=tf.paragraphs[0] if idx==0 else tf.add_paragraph() p.text=para prs.save(OUT) print(OUT) PY python "/tmp/workspace/cancer-prehabilitation-ppt/src/add_notes.py"

Running Command

python - <<'PY' from pptx import Presentation p='/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway_with_Speaker_Notes.pptx' prs=Presentation(p) print('slides',len(prs.slides)) for i, slide in enumerate(prs.slides,1): notes=[] for sh in slide.notes_slide.shapes: if sh.has_text_frame and 'Notes Placeholder' in sh.name: notes.append(sh.text_frame.text) txt=' '.join(notes).replace('\n',' | ') print(i, len(txt), txt[:90]) PY python - <<'PY' from zipfile import ZipFile p='/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway_with_Speaker_Notes.pptx' with ZipFile(p) as z: print('zip_integrity', 'OK' if z.testzip() is None else 'FAILED') print('notes_files',len([x for x in z.namelist() if x.startswith('ppt/notesSlides/notesSlide') and x.endswith('.xml')])) PY ls -lh "/tmp/workspace/cancer-prehabilitation-ppt/output/Cancer_Prehabilitation_Clinical_Pathway_with_Speaker_Notes.pptx"

Added slide-specific speaker notes to all 12 slides, including:
  • Suggested timing
  • Key talking points
  • Emphasis and cautions
  • Audience discussion prompts
  • Slide-to-slide transitions
  • Implementation tips and closing guidance

Cancer Prehabilitation Clinical Pathway with Speaker Notes

Presentation · PPTX

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