const pptxgen = require("pptxgenjs");

const pres = new pptxgen();
pres.layout = "LAYOUT_16x9";
pres.title = "How to Read a Basic CBC Test";
pres.author = "Orris Medical Education";

// ── COLOUR PALETTE ──────────────────────────────────────────────────────────
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  yellow:  "FFD600",   // accent highlight
  red:     "D32F2F",
  green:   "2E7D32",
  gray:    "546E7A",
  lightGray: "CFD8DC",
};

// ── HELPER FUNCTIONS ─────────────────────────────────────────────────────────

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// ── SLIDE 1 — TITLE ──────────────────────────────────────────────────────────
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  // Sub-title
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    fontSize: 9.5, color: C.gray, align: "left",
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}

// ── SLIDE 2 — WHAT IS A CBC? ──────────────────────────────────────────────────
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  addSectionLabel(s, "Overview", C.blue);
  addSlideNumber(s, 2);

  s.addText("What Is a CBC?", {
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    { icon: "⚪", title: "White Blood Cells", body: "Defend the body against infection, bacteria, viruses, and foreign invaders", x: 3.58 },
    { icon: "🟡", title: "Platelets", body: "Tiny cell fragments that stop bleeding by forming clots at injury sites", x: 6.78 },
  ];

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// ── SLIDE 3 — WHY IS IT ORDERED? ─────────────────────────────────────────────
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    fontSize: 28, bold: true, color: C.navy,
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    { num: "01", title: "Routine Check-up", desc: "Screening for blood disorders during annual health exams" },
    { num: "02", title: "Symptom Investigation", desc: "Fatigue, weakness, fever, bruising, or unexplained weight loss" },
    { num: "03", title: "Monitoring Chronic Illness", desc: "Track conditions like diabetes, kidney disease, or heart disease" },
    { num: "04", title: "Pre-operative Assessment", desc: "Ensure safe haemoglobin and platelet levels before surgery" },
    { num: "05", title: "Medication Monitoring", desc: "Chemotherapy, anticoagulants, and immunosuppressants can affect blood cells" },
    { num: "06", title: "Diagnosing Infections", desc: "Elevated WBC indicates bacterial or viral infection response" },
  ];

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      fontSize: 10, color: C.gray });
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}

// ── SLIDE 4 — RED BLOOD CELLS SECTION DIVIDER ────────────────────────────────
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    fontSize: 12, bold: true, color: "FFCDD2", charSpacing: 6 });
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    fontSize: 52, bold: true, color: C.white, lineSpacingMultiple: 1.1 });
  s.addText("RBC  •  Hemoglobin  •  Hematocrit  •  MCV  •  MCH  •  MCHC  •  RDW", {
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// ── SLIDE 5 — HEMOGLOBIN & HEMATOCRIT ────────────────────────────────────────
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  addSectionLabel(s, "Red Blood Cells", C.red);
  addSlideNumber(s, 5);

  s.addText("Hemoglobin (Hb) & Hematocrit (Hct)", {
    x: 0.38, y: 0.68, w: 9.2, h: 0.6,
    fontSize: 26, bold: true, color: C.navy,
  });

  // Hemoglobin
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    fill: { color: C.red }, line: { type: "none" }, rectRadius: 0.1 });
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    fontSize: 14, bold: true, color: C.white, valign: "middle", margin: 4 });

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    ["What it measures", "Amount of hemoglobin protein in whole blood (g/dL)"],
    ["Men (normal)", "13 – 18 g/dL"],
    ["Women (normal)", "12 – 16 g/dL"],
    ["Low (Anemia)", "< 12 g/dL — fatigue, pallor, dyspnoea"],
    ["High (Polycythaemia)", "> 18 g/dL — thickened blood, clot risk"],
  ];
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      fontSize: 10, color: C.gray, valign: "middle" });
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    fontSize: 14, bold: true, color: C.white, valign: "middle", margin: 4 });

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    ["What it measures", "% of blood volume occupied by RBCs"],
    ["Men (normal)", "41 – 53 %"],
    ["Women (normal)", "36 – 46 %"],
    ["Low", "< 36 % — anaemia, haemorrhage"],
    ["High", "> 52 % — dehydration, polycythaemia"],
  ];
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      fontSize: 10, bold: true, color: C.navy, valign: "middle" });
    s.addText(val, { x: 6.95, y: 1.92 + i * 0.55, w: 2.6, h: 0.52,
      fontSize: 10, color: C.gray, valign: "middle" });
  });
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// ── SLIDE 6 — RBC INDICES ─────────────────────────────────────────────────────
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  addSectionLabel(s, "Red Blood Cells", C.red);
  addSlideNumber(s, 6);

  s.addText("RBC Indices — Size & Colour of Red Cells", {
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    fontSize: 25, bold: true, color: C.navy,
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  const indices = [
    {
      abbr: "MCV", full: "Mean Corpuscular Volume",
      normal: "80 – 100 fL",
      low: "Microcytic anaemia\n(iron deficiency, thalassaemia)",
      high: "Macrocytic anaemia\n(B12/folate deficiency)",
      x: 0.3,
    },
    {
      abbr: "MCH", full: "Mean Corpuscular Haemoglobin",
      normal: "27 – 32 pg/cell",
      low: "Hypochromic cells\n(iron deficiency)",
      high: "Hyperchromic / B12 deficiency",
      x: 3.45,
    },
    {
      abbr: "MCHC", full: "Mean Corpuscular Hb Concentration",
      normal: "32 – 36 g/dL",
      low: "Iron deficiency, thalassaemia",
      high: "Hereditary spherocytosis",
      x: 6.6,
    },
  ];

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      fill: { color: C.silver }, line: { color: C.lightGray, pt: 1 }, rectRadius: 0.1 });
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      fontSize: 9, color: "FFCDD2", align: "center", italic: true });

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      fill: { color: C.green + "22" }, line: { color: C.green, pt: 1 }, rectRadius: 0.06 });
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    s.addText("HIGH:", { x: idx.x + 0.15, y: 3.98, w: 0.7, h: 0.3,
      fontSize: 10, bold: true, color: "B71C1C" });
    s.addText(idx.high, { x: idx.x + 0.15, y: 4.27, w: 2.7, h: 0.7,
      fontSize: 10, color: C.gray });
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}

// ── SLIDE 7 — WHITE BLOOD CELLS DIVIDER ──────────────────────────────────────
{
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  s.addShape("rect", { x: 0, y: 0, w: 10, h: 5.625, fill: { color: "0D47A1" } });
  s.addShape("ellipse", { x: 6.5, y: -1.5, w: 5.5, h: 5.5, fill: { color: "1565C0" }, line: { type: "none" } });
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  s.addText("SECTION 2", { x: 1.5, y: 1.3, w: 5, h: 0.4,
    fontSize: 12, bold: true, color: "BBDEFB", charSpacing: 6 });
  s.addText("White Blood\nCell Tests", { x: 1.5, y: 1.75, w: 7, h: 2.1,
    fontSize: 52, bold: true, color: C.white, lineSpacingMultiple: 1.1 });
  s.addText("Total WBC Count  •  Differential  •  Neutrophils  •  Lymphocytes  •  More", {
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    fontSize: 12, color: "BBDEFB", italic: true });
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}

// ── SLIDE 8 — TOTAL WBC COUNT ─────────────────────────────────────────────────
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  addSectionLabel(s, "White Blood Cells", C.blue);
  addSlideNumber(s, 8);

  s.addText("Total WBC Count", {
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    fontSize: 28, bold: true, color: C.navy,
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  // Normal range banner
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    fill: { color: C.blue }, line: { type: "none" }, rectRadius: 0.08 });
  s.addText("Normal Range in Adults: 4,500 – 11,000 cells/µL", {
    x: 0.38, y: 1.38, w: 9.3, h: 0.65,
    fontSize: 16, bold: true, color: C.white, align: "center", valign: "middle" });

  // Low / Normal / High visual
  const zones = [
    { label: "LEUKOPENIA", sub: "< 4,500/µL", desc: "Bone marrow suppression\nViral infections (HIV, hepatitis)\nAutoimmune disorders\nChemotherapy side effect", color: "E3F2FD", border: C.blue, icon: "⬇" },
    { label: "NORMAL", sub: "4,500 – 11,000/µL", desc: "No further WBC-related\nconcern in most cases", color: "E8F5E9", border: C.green, icon: "✓" },
    { label: "LEUKOCYTOSIS", sub: "> 11,000/µL", desc: "Bacterial infection\nInflammatory conditions\nLeukaemia\nPhysical or emotional stress", color: "FFEBEE", border: C.red, icon: "⬆" },
  ];

  zones.forEach((z, i) => {
    const x = 0.38 + i * 3.15;
    s.addShape("rect", { x, y: 2.2, w: 2.95, h: 3.05,
      fill: { color: z.color }, line: { color: z.border, pt: 1.5 }, rectRadius: 0.1 });
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    s.addText(z.label, { x, y: 2.82, w: 2.95, h: 0.38,
      fontSize: 13, bold: true, color: z.border, align: "center" });
    s.addText(z.sub, { x, y: 3.2, w: 2.95, h: 0.35,
      fontSize: 10, color: C.gray, align: "center", italic: true });
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    s.addText(z.desc, { x: x + 0.1, y: 3.65, w: 2.75, h: 1.45,
      fontSize: 10, color: C.navy, align: "left" });
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// ── SLIDE 9 — WBC DIFFERENTIAL ───────────────────────────────────────────────
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  addSectionLabel(s, "WBC Differential", C.blue);
  addSlideNumber(s, 9);

  s.addText("WBC Differential — Types of White Cells", {
    x: 0.38, y: 0.68, w: 9.2, h: 0.6,
    fontSize: 26, bold: true, color: C.navy,
  });

  const cells = [
    { name: "Neutrophils", pct: "50 – 70 %", abs: "1,800 – 7,700/µL", role: "First-line defence against bacteria and fungi", high: "Bacterial infection, steroid use", low: "Chemotherapy, aplastic anaemia", color: "1565C0" },
    { name: "Lymphocytes", pct: "20 – 40 %", abs: "1,000 – 4,800/µL", role: "B-cells (antibodies) & T-cells (cell immunity)", high: "Viral infections, CLL", low: "HIV, immunodeficiency", color: "00838F" },
    { name: "Monocytes", pct: "2 – 8 %", abs: "200 – 800/µL", role: "Clean up debris; present antigens to lymphocytes", high: "Chronic infection, monocytic leukaemia", low: "Aplastic anaemia, steroid use", color: "4527A0" },
    { name: "Eosinophils", pct: "1 – 4 %", abs: "100 – 500/µL", role: "Combat parasites and mediate allergic reactions", high: "Allergies, asthma, parasitic infection", low: "Steroid excess (Cushing's)", color: "E65100" },
    { name: "Basophils", pct: "0.5 – 1 %", abs: "20 – 100/µL", role: "Release histamine in allergic/inflammatory response", high: "Allergic reactions, CML", low: "Acute infection, hyperthyroidism", color: "AD1457" },
  ];

  // Table header
  const headers = ["Cell Type", "% Range", "Absolute Range", "Function & Clinical Notes"];
  const colW = [1.9, 1.2, 1.7, 4.8];
  const colX = [0.28, 2.18, 3.38, 5.08];

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      fontSize: 11, bold: true, color: C.white, valign: "middle", margin: 4 });
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  cells.forEach((c, i) => {
    const y = 1.82 + i * 0.72;
    const bg = i % 2 === 0 ? C.silver : C.white;
    s.addShape("rect", { x: 0.28, y, w: 9.42, h: 0.7, fill: { color: bg } });
    s.addShape("rect", { x: 0.28, y, w: 0.12, h: 0.7, fill: { color: c.color } });

    s.addText(c.name, { x: 0.45, y, w: 1.7, h: 0.7,
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    s.addText(c.abs, { x: colX[2], y, w: colW[2], h: 0.7,
      fontSize: 10, color: C.gray, valign: "middle" });
    s.addText([
      { text: c.role + "\n", options: { bold: false } },
      { text: "↑ ", options: { bold: true, color: C.red } },
      { text: c.high + "  ", options: {} },
      { text: "↓ ", options: { bold: true, color: C.blue } },
      { text: c.low, options: {} },
    ], { x: colX[3], y, w: colW[3], h: 0.7, fontSize: 9, color: C.navy, valign: "middle" });
  });
}

// ── SLIDE 10 — PLATELETS DIVIDER ──────────────────────────────────────────────
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  s.addShape("rect", { x: 0, y: 0, w: 10, h: 5.625, fill: { color: "1B5E20" } });
  s.addShape("ellipse", { x: 6.5, y: -1.5, w: 5.5, h: 5.5, fill: { color: "2E7D32" }, line: { type: "none" } });
  s.addShape("ellipse", { x: -1.5, y: 3.5, w: 4, h: 4, fill: { color: "2E7D32" }, line: { type: "none" } });

  s.addText("SECTION 3", { x: 1.5, y: 1.3, w: 5, h: 0.4,
    fontSize: 12, bold: true, color: "C8E6C9", charSpacing: 6 });
  s.addText("Platelet\nTests", { x: 1.5, y: 1.75, w: 7, h: 2.1,
    fontSize: 52, bold: true, color: C.white, lineSpacingMultiple: 1.1 });
  s.addText("Platelet Count  •  MPV  •  Thrombocytopenia  •  Thrombocytosis", {
    x: 1.5, y: 3.95, w: 8, h: 0.4,
    fontSize: 12, color: "C8E6C9", italic: true });
  s.addShape("rect", { x: 1.5, y: 3.85, w: 5.5, h: 0.06, fill: { color: C.yellow } });
}

// ── SLIDE 11 — PLATELETS ──────────────────────────────────────────────────────
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  s.addShape("rect", { x: 0, y: 0, w: 10, h: 5.625, fill: { color: C.silver } });
  addAccentBar(s, C.green);
  addSectionLabel(s, "Platelets", C.green);
  addSlideNumber(s, 11);

  s.addText("Platelet Count", {
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    fontSize: 28, bold: true, color: C.navy,
  });

  // Normal banner
  s.addShape("rect", { x: 0.38, y: 1.38, w: 9.3, h: 0.58,
    fill: { color: C.green }, line: { type: "none" }, rectRadius: 0.08 });
  s.addText("Normal Range: 150,000 – 400,000 /µL   |   Role: Haemostasis & Clot Formation", {
    x: 0.38, y: 1.38, w: 9.3, h: 0.58,
    fontSize: 13, bold: true, color: C.white, align: "center", valign: "middle" });

  // Two columns
  // Thrombocytopenia
  s.addShape("rect", { x: 0.38, y: 2.1, w: 4.55, h: 3.15,
    fill: { color: C.white }, line: { color: C.red, pt: 1.5 }, rectRadius: 0.1 });
  s.addShape("rect", { x: 0.38, y: 2.1, w: 4.55, h: 0.52,
    fill: { color: C.red }, line: { type: "none" }, rectRadius: 0.1 });
  s.addText("THROMBOCYTOPENIA  (Low Platelets < 150,000)", {
    x: 0.5, y: 2.1, w: 4.35, h: 0.52,
    fontSize: 11, bold: true, color: C.white, valign: "middle", margin: 4 });

  const thrombLow = [
    "Mild (100–150k): Usually no symptoms",
    "Moderate (50–100k): Increased bruising risk",
    "Severe (< 50k): Spontaneous bleeding risk",
    "< 20k: Life-threatening haemorrhage",
    "Causes: ITP, DIC, dengue, B12 deficiency,",
    "  hypersplenism, chemotherapy",
  ];
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    s.addText(t, { x: 0.52, y: 2.72 + i * 0.4, w: 4.2, h: 0.38,
      fontSize: 10, color: i < 4 ? C.navy : C.gray, bullet: i >= 0 });
  });

  // Thrombocytosis
  s.addShape("rect", { x: 5.13, y: 2.1, w: 4.55, h: 3.15,
    fill: { color: C.white }, line: { color: C.teal, pt: 1.5 }, rectRadius: 0.1 });
  s.addShape("rect", { x: 5.13, y: 2.1, w: 4.55, h: 0.52,
    fill: { color: C.teal }, line: { type: "none" }, rectRadius: 0.1 });
  s.addText("THROMBOCYTOSIS  (High Platelets > 400,000)", {
    x: 5.25, y: 2.1, w: 4.35, h: 0.52,
    fontSize: 11, bold: true, color: C.white, valign: "middle", margin: 4 });

  const thrombHigh = [
    "Reactive (most common): inflammatory response",
    "Causes: infection, iron deficiency, surgery,",
    "  post-splenectomy, inflammatory disease",
    "Primary / Essential Thrombocythaemia:",
    "  Bone marrow overproduction",
    "Risk: clot formation if very elevated",
  ];
  thrombHigh.forEach((t, i) => {
    s.addText(t, { x: 5.27, y: 2.72 + i * 0.4, w: 4.2, h: 0.38,
      fontSize: 10, color: i < 3 ? C.navy : C.gray });
  });
}

// ── SLIDE 12 — COMPLETE REFERENCE TABLE ──────────────────────────────────────
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  addAccentBar(s, C.navy);
  addSectionLabel(s, "Quick Reference", C.navy);
  addSlideNumber(s, 12);

  s.addText("CBC Normal Ranges — At a Glance", {
    x: 0.38, y: 0.68, w: 9.2, h: 0.55,
    fontSize: 26, bold: true, color: C.navy,
  });

  const rows = [
    ["Parameter", "Normal Range", "Low Concern", "High Concern", "hdr"],
    ["Haemoglobin (Men)", "13 – 18 g/dL", "Anaemia / bleeding", "Polycythaemia", "red"],
    ["Haemoglobin (Women)", "12 – 16 g/dL", "Anaemia", "Polycythaemia", "red"],
    ["Hematocrit (Men)", "41 – 53 %", "Anaemia", "Dehydration / polycythaemia", "red"],
    ["RBC (Men/Women)", "4.6–6.2 / 4.2–5.4 M/µL", "Anaemia", "Polycythaemia", "red"],
    ["MCV", "80 – 100 fL", "Microcytic (iron def)", "Macrocytic (B12/folate def)", "red"],
    ["WBC", "4,500 – 11,000 /µL", "Infection risk / BM failure", "Infection / leukaemia", "blue"],
    ["Neutrophils", "50 – 70 %", "Neutropenia (chemo, viral)", "Bacterial infection", "blue"],
    ["Lymphocytes", "20 – 40 %", "HIV / immunodeficiency", "Viral / CLL", "blue"],
    ["Platelets", "150,000 – 400,000 /µL", "Bleeding risk", "Thrombosis risk", "green"],
  ];

  const colW2 = [2.1, 2.0, 2.5, 2.85];
  const colX2 = [0.28, 2.38, 4.38, 6.88];

  rows.forEach((r, ri) => {
    const y = 1.35 + ri * 0.42;
    const isHdr = r[4] === "hdr";
    const bg = isHdr ? C.navy : (ri % 2 === 0 ? C.silver : C.white);
    s.addShape("rect", { x: 0.28, y, w: 9.42, h: 0.42, fill: { color: bg } });

    // Left accent by type
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      const accentColor = r[4] === "red" ? C.red : r[4] === "blue" ? C.blue : C.green;
      s.addShape("rect", { x: 0.28, y, w: 0.1, h: 0.42, fill: { color: accentColor } });
    }

    r.slice(0, 4).forEach((cell, ci) => {
      s.addText(cell, {
        x: colX2[ci] + (ci === 0 ? 0.14 : 0), y, w: colW2[ci], h: 0.42,
        fontSize: isHdr ? 11 : 10,
        bold: isHdr || ci === 0,
        color: isHdr ? C.white : ci === 0 ? C.navy : C.gray,
        valign: "middle", margin: 3,
      });
    });
  });
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// ── SLIDE 13 — ANEMIA CLASSIFICATION ─────────────────────────────────────────
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  addAccentBar(s, C.red);
  addSectionLabel(s, "Clinical Application", C.red);
  addSlideNumber(s, 13);

  s.addText("Using CBC to Classify Anaemia", {
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    fontSize: 26, bold: true, color: C.navy,
  });

  const types = [
    {
      title: "Microcytic Anaemia", color: C.red, x: 0.28, y: 1.45,
      markers: "MCV < 80 fL • Low MCH",
      causes: ["Iron deficiency anaemia", "Thalassaemia", "Anaemia of chronic disease", "Lead poisoning"],
    },
    {
      title: "Normocytic Anaemia", color: C.blue, x: 3.45, y: 1.45,
      markers: "MCV 80–100 fL • Normal MCH",
      causes: ["Acute blood loss", "Haemolytic anaemia", "Aplastic anaemia", "Renal failure"],
    },
    {
      title: "Macrocytic Anaemia", color: C.teal, x: 6.62, y: 1.45,
      markers: "MCV > 100 fL • High MCH",
      causes: ["Vit B12 deficiency", "Folate deficiency", "Hypothyroidism", "Alcoholism"],
    },
  ];

  types.forEach(t => {
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      fill: { color: C.white }, line: { color: t.color, pt: 2 }, rectRadius: 0.1 });
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  s.addText("Tip: RDW (normal 11.5–14.5%) helps differentiate iron deficiency (high RDW) from thalassaemia (normal RDW) in microcytic anaemia.", {
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    fontSize: 9.5, color: C.teal, italic: true,
  });
}

// ── SLIDE 14 — WHEN TO SEEK MEDICAL ATTENTION ────────────────────────────────
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  addSectionLabel(s, "Warning Signs", "E65100");
  addSlideNumber(s, 14);

  s.addText("When to Seek Medical Attention", {
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    fontSize: 26, bold: true, color: C.navy,
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    { icon: "🔴", label: "CRITICAL — Immediate", items: ["Hb < 7 g/dL (severe anaemia)", "Platelets < 20,000/µL (bleeding risk)", "WBC > 30,000/µL (possible leukaemia)", "Absolute neutrophils < 500/µL (severe risk)"], color: C.red },
    { icon: "🟡", label: "URGENT — Same Day", items: ["Hb 7–9 g/dL with symptoms", "Platelets 20–50k with bruising", "WBC > 20,000 with fever / chills", "Blast cells seen on differential"], color: "E65100" },
    { icon: "🟢", label: "ROUTINE — Follow Up", items: ["Mild isolated anaemia (Hb 10–12)", "Mild thrombocytosis (400–600k)", "Borderline WBC (11–15k, no symptoms)", "RDW or MCV mildly out of range"], color: C.green },
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  warnings.forEach((w, i) => {
    const x = 0.35 + i * 3.18;
    s.addShape("rect", { x, y: 1.45, w: 3.0, h: 3.85,
      fill: { color: C.silver }, line: { color: w.color, pt: 2 }, rectRadius: 0.1 });
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// ── SLIDE 15 — KEY TAKEAWAYS & CLOSING ───────────────────────────────────────
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  s.addText("KEY TAKEAWAYS", { x: 0.5, y: 0.3, w: 2.5, h: 0.4,
    fontSize: 11, bold: true, color: C.white, align: "center", valign: "middle", margin: 0 });

  s.addText("Reading a CBC — Summary", { x: 0.5, y: 0.82, w: 8, h: 0.65,
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  const takes = [
    { n: "1", t: "Always compare to lab reference ranges", d: "Normal values vary slightly by laboratory and patient demographics." },
    { n: "2", t: "Look at the pattern, not one value", d: "MCV + MCH + RDW together reveal anaemia type better than Hb alone." },
    { n: "3", t: "Differential gives WBC meaning", d: "A high WBC from neutrophilia suggests bacterial infection; lymphocytosis suggests viral." },
    { n: "4", t: "Platelets + clinical picture matter", d: "Mild thrombocytopenia with no bleeding may require only monitoring." },
    { n: "5", t: "Repeat tests confirm trends", d: "A single abnormal CBC often needs repeat testing before diagnosis." },
  ];

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    s.addShape("ellipse", { x: 0.5, y: y + 0.05, w: 0.42, h: 0.42,
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// ── WRITE FILE ────────────────────────────────────────────────────────────────
pres.writeFile({ fileName: "/home/daytona/workspace/cbc-ppt/How_to_Read_a_Basic_CBC_Test.pptx" })
  .then(() => console.log("SUCCESS: PPTX written"))
  .catch(e => { console.error("ERROR:", e); process.exit(1); });

Successfully replaced 1 instance(s) of the string in '/home/daytona/workspace/cbc-ppt/build.js'

Successfully replaced 1 instance(s) of the string in '/home/daytona/workspace/cbc-ppt/build.js'