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I’m a 1st year medical student which has his university exam in 10days and has started nothing. My university is Marwar Rajasthan which is affili to RUHS Rajasthan. I am attaching the this years RUHS paper of 3 exams which have happened so far. Analysis of them thoroughly and make me a guide to prepare for the university exam of all three subjects and their paper 1 and 2 . These are anatomy paper 1 and 2 and Physio paper 1. The paper will be same on same pattern and scenario. Analyse and predict the possibility and make a guide for next 10days according to the Marwar schedule im attaching
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MARWAR MEDICAL UNIVERSITY - FIRST MBBS EXAM GUIDE
Complete 10-Day Preparation Plan (July 30 - August 9, 2026)
Based on RUHS July 2026 Paper Analysis
EXAM TIMETABLE (Marwar Medical University)
| Date | Day | Subject |
|---|---|---|
| 10 Aug | Monday | Human Anatomy Paper I |
| 12 Aug | Wednesday | Human Anatomy Paper II |
| 14 Aug | Friday | Physiology Paper I |
| 17 Aug | Monday | Physiology Paper II |
| 19 Aug | Wednesday | Biochemistry Paper I |
| 21 Aug | Friday | Biochemistry Paper II |
Focus here: Anatomy P1 (10 Aug), Anatomy P2 (12 Aug), Physiology P1 (14 Aug)
PAPER PATTERN ANALYSIS (RUHS July 2026 Pattern)
Every paper follows this exact structure - 100 marks, 3 hours:
| Section | Type | Marks | Details |
|---|---|---|---|
| Q1 | MCQs | 20×1 = 20 | 20 clinical MCQs |
| Q2 | Long Essay (Structured) | 3+3+4 = 10 | One topic, 3 sub-parts |
| Q3 | Explain Why | 5×3 = 15 | 5 short reasoning answers |
| Q4 | Short Notes | 4×5 = 20 | 4 topics (5 marks each) |
| Q5 | Short Notes | 3×5 = 15 | 3 topics (5 marks each) |
| Q6 | Short Notes | 4×5 = 20 | 4 topics (5 marks each) |
Key insight: MCQs are ALL clinical scenario-based (patient presents with...). Short notes = 11 topics per paper. This is your main scoring zone.
ANATOMY PAPER I - COMPLETE ANALYSIS
Topics Covered in RUHS July 2026
MCQs (Q1) - Anatomy P1:
- Clavicle fracture - junction of two curvatures
- Missing carpal bone in 10yr old - Pisiform (last to ossify)
- Surgical neck humerus relations - Axillary nerve + circumflex humeral vessels
- Brown Sequard Syndrome (T10 stab)
- Multiple demyelinating lesions - Oligodendrocytes affected (MS)
- Dry mouth + dilated pupils - Parasympathetic pathway
- Wernicke's area - fluent nonsensical speech
- Epidural hemorrhage - Middle meningeal artery
- Lumbar puncture - L2-L3 level
- TMJ dislocation - Lateral pterygoid muscle
- Breast lump axillary tail of Spence - Quadrangular space
- Drooping shoulder after hockey blow - Trapezius (CN XI)
- Painless tongue ulcer lymph drainage - Submandibular nodes
- Small mandible + cleft palate infant - 1st pharyngeal arch
- Lymph capillaries absent - Epidermis/Enamel/Cornea EXCEPT Pancreas
- Pseudoganglion nerve - Axillary nerve
- Blood brain barrier - Area postrema is OUT of BBB
- Intracerebellar nuclei - Globose nucleus is NOT intracerebellar (it IS - trick: Red nucleus is NOT)
- Muscle supplied by two nerves - Flexor digitorum profundus
- Muscle dividing axillary artery - Pectoralis minor
Long Essay Q2: TONGUE
- External features
- Muscles of tongue
- Nerve supply and development
Explain Why (Q3):
- 1st CMC joint has more movements
- Shoulder dislocation is inferior
- Facial muscles = muscles of expression
- Maxillary sinusitis is chronic
- Hypothalamus = Head ganglion of ANS
Short Notes (Q4, Q5, Q6):
- Thyroid gland (microanatomy + development)
- Internal Capsule
- Cubital fossa
- Deltoid muscle
- Lateral medullary syndrome (Wallenberg)
- Otic ganglion
- Ulnar nerve in hand
- Cadaver as first teacher
- Circle of Willis
- Styloid apparatus
- Dorsal digital expansion
HIGH-PROBABILITY TOPICS FOR ANATOMY P1 (YOUR EXAM - 10 Aug)
Based on pattern, topics NOT asked in RUHS July 2026 that are standard syllabus:
Almost Certain Long Essay (Q2) Candidates:
- Brachial plexus (not asked, high weightage)
- Knee joint (formation, ligaments, bursae, applied)
- Femoral triangle (contents, floor, applied)
- Cervical vertebra / vertebral column
Predict for Short Notes:
- Carpal tunnel syndrome (clinical anatomy)
- Rotator cuff muscles
- Brachial artery
- Median nerve in hand (counterpart to ulnar nerve asked)
- Wrist joint
- Elbow joint
- Femoral nerve / saphenous nerve
- Popliteal fossa
- Breast (anatomy + lymphatic drainage)
MCQ topics likely to reappear or be similar:
- Dermatomes
- Spinal cord tracts
- Nerve injuries (radial, median, ulnar)
- Skull foramina
- Vertebral levels of structures
ANATOMY PAPER II - COMPLETE ANALYSIS
Topics in RUHS July 2026 - Anatomy P2 (28/07/2026):
MCQs:
- Stab below inguinal ligament - Femoral nerve (loss of extension, knee reflex)
- Superior mediastinum structures - Right recurrent laryngeal nerve affected
- First dorsal web space numb, dorsum normal - Superficial peroneal nerve
- Coarctation of aorta (rib notching) - Internal thoracic + posterior intercostal anastomosis
- Posterior gastric ulcer bleeding - Splenic artery
- Bladder catheterization - least dilatable = Membranous urethra
- Esophageal varices in alcoholic - Left gastric + accessory hemiazygos veins
- Sensory loss medial leg/foot post varicose surgery - Saphenous nerve
- Bilious vomiting neonate - Superior mesenteric artery (midgut rotation)
- Thoracocentesis 8th intercostal space - Lower border of intercostal space
- NOT at sternal angle level - Apex beat (not at sternal angle)
- Cap-like structure on contrast GIT radiograph - Proximal duodenum (duodenal cap)
- Medial meniscus injury more common - Tibial collateral ligament attachment
- Prostatic venous plexus spread - Vertebrae
- Stereocilia present - Vas deferens
- Placenta develops from - Decidua basalis and chorion
- Cruciate anastomosis does NOT include - Lateral circumflex femoral artery
- NOT paramesonephric duct derivative - Appendix of epididymis
- Somites develop from - Paraxial intraembryonic mesoderm
- Turner's syndrome all EXCEPT - Numerous ovarian follicles (streak gonads)
Long Essay Q2: ANAL CANAL
- Interior structure
- Blood supply and lymphatic drainage
- Applied anatomy
Explain Why (Q3):
- Pain of cholecystitis referred to right shoulder
- Fluid in hepatorenal pouch post gall bladder surgery
- Foot drop after fracture neck of fibula
- Down syndrome develops
- Paradoxical respiration
Short Notes (Q4, Q5, Q6):
- Microscopic anatomy of vermiform appendix
- Left coronary artery
- Lesser sac
- Adductor canal
- Inguinal hernia
- Gluteus maximus and structures under its cover
- Superior mediastinum
- Principles of Communication (AETCOM)
- Development of kidney
- Gall bladder
- Lymphatic drainage of stomach
HIGH-PROBABILITY TOPICS FOR ANATOMY P2 (YOUR EXAM - 12 Aug)
Almost Certain Long Essay Candidates (not asked in July):
- Inguinal canal (very high yield - only short note asked, long essay due)
- Liver (lobes, ligaments, blood supply, applied)
- Heart (chambers, blood supply)
- Portal vein (tributaries, portal hypertension)
- Kidney (structure, relations, blood supply)
Short Notes high probability:
- Pectinate line / anal sphincters
- Processus vaginalis
- Femoral hernia (vs inguinal)
- Peritoneum / greater omentum
- Ureter (course, constrictions)
- Prostate gland
- Uterus / broad ligament
- Right coronary artery
- Hepatic portal circulation
- Meckel's diverticulum
- Pharyngeal arches (MCQ came - short note likely)
- Down syndrome (Explain Why came - short note likely)
PHYSIOLOGY PAPER I - COMPLETE ANALYSIS
Topics in RUHS July 2026 - Physiology P1 (30/07/2026):
MCQs:
- Weight loss + sweating + tachycardia + exophthalmos - Graves disease
- Diabetes Mellitus long-term control - HbA1c
- Parkinson's (festinant gait, difficulty initiating movement) - Substantia nigra
- Post-menopausal hormones - FSH increases, LH decreases
- Rinne test positive right ear, BC > AC left ear - Left ear Sensorineural deafness
- Turner syndrome - Barr bodies = ZERO (45 XO)
- Pain + temperature loss upper limb, touch preserved - Syringomyelia
- Fatigue + diplopia worsening with activity - Myasthenia gravis
- Non-fluent speech, comprehension intact - Broca's area lesion
- Swaying + nystagmus + falls - Flocculonodular lobe (archicerebellum)
- Pituitary adenoma - bitemporal hemianopia - Optic chiasma
- Loud snoring + morning headache + excessive daytime sleepiness - Obstructive sleep apnea
- EEG during math problem - Beta waves
- Left dorsal column lesion - Vibration lost from LEFT side below lesion
- Aldosterone escape - Atrial natriuretic factor
- Total body water measured by - Deuterium oxide
- Bone resorption cells - Osteoclast
- Stretch reflex receptor - Muscle spindle
- Colour vision receptor - Cones
- Sertoli cells secrete - Androgen binding protein
Long Essay Q2: REFERRED PAIN
- Define referred pain (2 marks)
- Theories with diagram (5 marks)
- Central inhibition of pain (3 marks)
Explain Why (Q3):
- RBC lysis when Na-K-ATPase stops
- Weakness improves with activity in Lambert-Eaton syndrome
- Carbidopa given with Levodopa in Parkinson's
- Infertility in undescended testis
- Increased heart rate in hyperthyroidism
Short Notes (Q4, Q5, Q6):
- Theories of ageing
- Metabolic syndrome
- Benefits of yoga
- Physiological response to cold exposure
- Indicators of ovulation
- Acromegaly
- Impedance matching
- Responsibilities of Physician towards patient
- UMN vs LMN lesion differences
- Ionic basis of action potential
- Androgen resistance syndrome
HIGH-PROBABILITY TOPICS FOR PHYSIOLOGY P1 (YOUR EXAM - 14 Aug)
Almost Certain Long Essay Candidates:
- Action potential (ionic basis was a short note - long essay next)
- Cardiac cycle (not touched yet)
- Neuromuscular junction (myasthenia asked in MCQ)
- Pain (referred pain was long essay - gate control theory also likely)
- Renal regulation (Aldosterone asked in MCQ)
Short Notes high probability:
- Neuromuscular junction in detail
- Resting membrane potential
- Cerebellar functions (MCQ came)
- Basal ganglia (Parkinson MCQ came)
- Thyroid hormones mechanism (Graves MCQ)
- Insulin mechanism and effects
- Erythropoiesis
- Starling's law
- Juxtaglomerular apparatus
- Spirometry / lung volumes
- ECG waves and intervals
- Blood groups
- Platelet plug formation / hemostasis
- Fever (pyrogens, mechanism)
- GH and acromegaly (short note asked, long essay possible)
10-DAY STUDY PLAN
Today: July 30 (Thursday) | Anatomy P1: Aug 10 | Anatomy P2: Aug 12 | Physio P1: Aug 14
DAY 1 - July 30 (Today, Thursday)
ANATOMY P1 - Upper Limb
- Morning (4 hrs): Brachial plexus (roots, trunks, divisions, cords, branches + injuries)
- Afternoon (4 hrs): Shoulder joint + rotator cuff + Cubital fossa + Carpal tunnel
- Evening (2 hrs): Revise MCQ hot topics: Surgical neck humerus, Clavicle fracture, Median/Ulnar/Radial nerve injuries
Target: Be able to draw brachial plexus from memory; write short notes on rotator cuff, cubital fossa
DAY 2 - July 31 (Friday)
ANATOMY P1 - Head & Neck + Neuroanatomy
- Morning (4 hrs): Tongue (external features, muscles, nerve supply, development) - this exact topic came in RUHS, prepare as long essay
- Afternoon (3 hrs): Circle of Willis, Internal capsule, Blood-brain barrier, Lateral medullary syndrome
- Evening (3 hrs): Cranial nerves (V, VII, IX, X, XII - high yield), Pharyngeal arches, TMJ
Target: Write full tongue answer; know which artery = epidural hemorrhage (middle meningeal); lumbar puncture level (L3-L4 safe)
DAY 3 - August 1 (Saturday)
ANATOMY P1 - Lower Limb + Revision
- Morning (4 hrs): Femoral triangle (floor, roof, contents), Adductor canal, Popliteal fossa
- Afternoon (3 hrs): Knee joint ligaments, menisci, bursae; Femoral nerve; Sciatic nerve
- Evening (3 hrs): Spinal cord tracts (Brown-Sequard, spinothalamic, dorsal column) - MCQ hotspot
Target: Draw femoral triangle; understand nerve injury patterns at various levels
DAY 4 - August 2 (Sunday)
ANATOMY P1 - Full Revision + MCQ Practice
- Morning (3 hrs): Deltoid muscle, Otic ganglion, Dorsal digital expansion, Styloid apparatus, Ulnar nerve in hand - ALL from Q5/Q6 pattern
- Afternoon (3 hrs): Hypothalamus (head ganglion of ANS - Explain Why), Maxillary sinus (why chronic), Shoulder dislocation (why inferior)
- Evening (4 hrs): Write at least 5 short notes timed (5 mins per note = key facts only)
DAY 5 - August 3 (Monday)
ANATOMY P2 - Abdomen (Priority)
- Morning (4 hrs): Inguinal canal (boundaries, contents, inguinal hernia - direct vs indirect) - HIGH PROBABILITY long essay
- Afternoon (4 hrs): Anal canal (interior, blood supply, lymphatics, applied - exact same as RUHS essay structure), Liver (lobes, ligaments, peritoneum)
- Evening (2 hrs): Portal circulation, lesser sac, hepatorenal pouch
Target: Write full inguinal canal essay; know portal-systemic anastomoses (varices MCQ)
DAY 6 - August 4 (Tuesday)
ANATOMY P2 - Thorax + Pelvis
- Morning (4 hrs): Heart (chambers, blood supply - left coronary artery was short note), Mediastinum (superior mediastinum - short note asked), Rib notching/coarctation
- Afternoon (3 hrs): Kidney (structure, hilum, blood supply, development), Ureter (course, constrictions), Development of kidney
- Evening (3 hrs): Pelvis - Prostate, Uterus, Bladder, Urethra (membranous = narrowest)
DAY 7 - August 5 (Wednesday)
ANATOMY P2 - Development + Lower Limb + Revision
- Morning (3 hrs): Embryology - Turner's syndrome, Down syndrome (Explain Why), Somites (paraxial mesoderm), Placenta, Paramesonephric/Mesonephric duct derivatives
- Afternoon (3 hrs): Gluteus maximus + structures under cover; Adductor canal; Femoral hernia vs inguinal hernia
- Evening (4 hrs): Short notes practice - Gall bladder, Lymph drainage stomach, Vermiform appendix, Gut rotation (midgut volvulus MCQ)
DAY 8 - August 6 (Thursday)
PHYSIOLOGY P1 - General + Neurophysiology
- Morning (4 hrs): Action potential (ionic basis - short note in RUHS, write as long essay), Resting membrane potential, Neuromuscular junction (myasthenia gravis mechanism)
- Afternoon (4 hrs): Cerebellum (flocculonodular lobe, spinocerebellum, neocerebellum), Basal ganglia + Parkinson's pathology, UMN vs LMN lesion
- Evening (2 hrs): Sensory pathways (spinothalamic, dorsal column, syringomyelia, Brown-Sequard)
Target: Write ionic basis of AP; draw synapse; distinguish UMN vs LMN table
DAY 9 - August 7 (Friday)
PHYSIOLOGY P1 - Endocrinology + Special Senses + Autonomic
- Morning (3 hrs): Thyroid (Graves' disease, TSH, T3/T4 mechanism, hyperthyroidism - heart rate), Adrenal cortex (aldosterone, ANF/escape), Reproductive hormones (Sertoli cell = ABP, FSH/LH changes)
- Afternoon (3 hrs): Vision (cones/colour, optic pathway - chiasma = bitemporal hemianopia), Hearing (Rinne/Weber test interpretation), Sleep physiology (OSA, EEG waves)
- Evening (4 hrs): Short notes - Acromegaly/GH, Metabolic syndrome, Androgen resistance syndrome, Indicators of ovulation, Theories of ageing
DAY 10 - August 8-9 (Weekend - 2 days before Anatomy P1)
FULL REVISION + PREDICT
August 8 (Saturday) - Anatomy P1 Final Revision:
- 3 hrs: Re-read all short notes written; Upper limb nerves/arteries
- 2 hrs: Neuroanatomy MCQ revision (which nerve = pseudoganglion = axillary; BBB areas out = area postrema)
- 2 hrs: Predict and prepare 5 likely short note topics not yet covered
- 2 hrs: Write mock Q2 (Long Essay) on Brachial Plexus timed
August 9 (Sunday) - Anatomy P2 Preview:
- 3 hrs: Inguinal canal long essay + abdominal anatomy recap
- 3 hrs: Development topics (pharyngeal arches, kidney, gonads)
- 2 hrs: Thorax (heart, mediastinum)
SUBJECT-WISE MUST-DO TOPICS (High Yield Summary)
ANATOMY PAPER I - TOP PRIORITIES
Long Essay (10 marks) - Most likely:
- Brachial plexus - draw + list branches + nerve injury patterns
- Knee joint OR Hip joint
- Tongue - if not asked in your paper, prepare as backup
Short Notes (5 marks each) - Must prepare ALL of these:
| Topic | Why Important |
|---|---|
| Rotator cuff | Upper limb - classic short note |
| Carpal tunnel syndrome | Clinical + anatomical |
| Cubital fossa | Asked in RUHS P1 directly |
| Median nerve in hand | Counterpart to Ulnar nerve asked |
| Femoral triangle | Classic P1 topic |
| Popliteal fossa | Lower limb high yield |
| Knee joint ligaments | MCQ came on meniscus, short note likely |
| Breast lymphatic drainage | Classic |
| Internal capsule | Asked in RUHS directly |
| Circle of Willis | Asked in RUHS directly |
| Lateral medullary syndrome | Asked in RUHS directly |
| Otic ganglion | Asked in RUHS directly |
| Dorsal digital expansion | Asked in RUHS directly |
Explain Why (3 marks each):
- Shoulder dislocates inferiorly (no rotator cuff below)
- Hypothalamus = head ganglion of ANS
- Facial muscles = muscles of expression (no deep fascia)
- 1st CMC joint has more movements (saddle joint)
- Maxillary sinusitis is more chronic (ostium opens high up)
- Why clavicle fractures at junction of curvatures
ANATOMY PAPER II - TOP PRIORITIES
Long Essay (10 marks) - Most likely:
- Inguinal canal - almost certain
- Liver - structure, surfaces, blood supply, applied
- Kidney - structure, relations, blood supply, development
Short Notes - Must prepare:
| Topic | Why Important |
|---|---|
| Inguinal hernia (direct vs indirect) | RUHS short note - now long essay likely |
| Anal canal | Was long essay in RUHS - may be short note in yours |
| Left coronary artery | Asked directly in RUHS |
| Right coronary artery | Counterpart |
| Gall bladder | Asked in RUHS |
| Development of kidney | Asked in RUHS |
| Stomach lymphatics | Asked in RUHS |
| Superior mediastinum | Asked in RUHS |
| Femoral hernia | Related to inguinal canal topic |
| Portal vein | Portal-systemic anastomoses |
| Meckel's diverticulum | Embryology high yield |
| Down syndrome development | Explain Why in RUHS |
Explain Why:
- Pain of cholecystitis referred to right shoulder (phrenic nerve C3,4,5)
- Fluid collects in hepatorenal pouch (Morrison's pouch = most dependent)
- Foot drop after fibula neck fracture (common peroneal nerve)
- Down syndrome: nondisjunction trisomy 21
- Paradoxical respiration in open chest injury
PHYSIOLOGY PAPER I - TOP PRIORITIES
Long Essay (10 marks) - Most likely:
- Neuromuscular junction (NMJ) - myasthenia MCQ = NMJ will be essay
- Cardiac cycle - pressure-volume, heart sounds
- Renal tubular function / Regulation of ECF
- Pain - if referred pain was July's - gate control theory possible
Short Notes - Must prepare:
| Topic | Why Important |
|---|---|
| Ionic basis of action potential | Was short note in RUHS - know thoroughly |
| NMJ and Myasthenia Gravis | MCQ linkage |
| Lambert-Eaton vs Myasthenia | Explain Why in RUHS |
| Basal ganglia / Parkinson's | MCQ linkage |
| Cerebellar lobes and functions | MCQ on flocculonodular |
| UMN vs LMN lesion | Asked in RUHS |
| Aldosterone mechanism + ANF escape | Asked in RUHS |
| Graves' disease / Thyroid | MCQ linkage |
| Sertoli cell functions | MCQ - secretes ABP |
| HbA1c | MCQ - long term DM control |
| Blood-brain barrier | Linkage with Anatomy |
| Spirometry + lung volumes | Very high yield, not yet asked |
| ECG waves | Classic short note |
| Erythropoiesis | High yield |
| Starling's law | Classic |
Explain Why:
- RBC lysis when Na-K-ATPase stops (cell swells - osmotic)
- Levodopa given with Carbidopa (prevent peripheral conversion)
- Weakness improves with activity in Lambert-Eaton (VGCCs)
- Undescended testis = infertility (high temperature, spermatogenesis fails)
- Tachycardia in hyperthyroidism (beta adrenergic sensitivity)
MCQ STRATEGY (20 marks - Clinical Scenarios)
All MCQs follow this pattern: "Patient presents with X. What is Y?"
Anatomy P1 MCQ Hot Topics to Revise:
- All nerve injury syndromes (wrist drop = radial, claw hand = ulnar, pope's blessing = median)
- Spinal cord syndromes (Brown-Sequard, Syringomyelia, Tabes dorsalis)
- Lumbar puncture = L3-L4 (safe), actually needle at L3-4 space
- Epidural haematoma = Middle meningeal artery
- Subdural haematoma = bridging veins
- TMJ dislocation = lateral pterygoid
- Areas outside BBB: Area postrema, median eminence, pineal gland, subfornical organ
- Lymph drainage of tongue tip = submental; lateral tongue = submandibular; posterior = deep cervical
Anatomy P2 MCQ Hot Topics:
- Coarctation of aorta = rib notching (internal thoracic-intercostal anastomosis)
- Esophageal varices = portal hypertension, left gastric vein
- Posterior gastric ulcer erodes = splenic artery
- Duodenal cap = 1st part duodenum
- Medial meniscus injury more common = attached to tibial collateral ligament (less mobile)
- Turner's syndrome = 45 XO, streak ovaries, NO follicles, sterile, zero Barr bodies
- Prostatic cancer spreads to vertebrae via prostatic venous plexus
- Foot drop = common peroneal nerve (fibula neck)
Physiology P1 MCQ Hot Topics:
- Graves disease = weight loss + sweating + tachycardia + exophthalmos
- HbA1c = long term DM control (6-8 weeks)
- Parkinson = substantia nigra (dopamine loss)
- Rinne: BC > AC = conductive deafness (ipsilateral); AC > BC = normal or sensorineural
- Turner = 45 XO = 0 Barr bodies
- Syringomyelia = cape-like distribution, loss of pain/temperature, touch preserved
- Beta waves = active thinking/problem solving
- Dorsal column lesion = ipsilateral loss of vibration/proprioception
- Aldosterone escape = ANF/atrial natriuretic factor
- Sertoli cells = Androgen Binding Protein (ABP)
QUICK REFERENCE: WHAT TO WRITE IN SHORT NOTES (5 marks = ~1.5 page)
Format for every short note:
- Definition / Introduction (1-2 lines)
- Key anatomical facts / points (numbered list, 4-5 points)
- Clinical/Applied significance (1-2 points)
- Small diagram if applicable (even rough)
Time allocation in exam:
- MCQs: 20 min (1 min each)
- Long Essay Q2: 20 min
- Q3 (Explain Why): 20 min (4 min each)
- Q4 (4 short notes): 25 min
- Q5 (3 short notes): 18 min
- Q6 (4 short notes): 25 min
- Review: 12 min
DAILY STUDY HOURS RECOMMENDED
| Day | Date | Focus | Hours |
|---|---|---|---|
| 1 | 30 Jul (Today) | Anatomy P1 - Upper Limb | 8-10 |
| 2 | 31 Jul | Anatomy P1 - H&N + Neuro | 8-10 |
| 3 | 1 Aug | Anatomy P1 - Lower Limb | 8-10 |
| 4 | 2 Aug | Anatomy P1 - Full revision | 8 |
| 5 | 3 Aug | Anatomy P2 - Abdomen | 8-10 |
| 6 | 4 Aug | Anatomy P2 - Thorax + Pelvis | 8-10 |
| 7 | 5 Aug | Anatomy P2 - Development + Revision | 8 |
| 8 | 6 Aug | Physio P1 - General + Neuro | 8-10 |
| 9 | 7 Aug | Physio P1 - Endo + Special senses | 8-10 |
| 10 | 8-9 Aug | Full revision + mock writing | 6 per day |
BOOKS TO USE (Minimum, most efficient)
- Anatomy: BD Chaurasia (Upper Limb + Lower Limb for P1; Thorax + Abdomen for P2) - read highlighted points only
- Neuroanatomy: Snell's Clinical Neuroanatomy (relevant chapters only)
- Physiology: AK Jain (concise) OR Sembulingam - tabular format chapters
- For MCQs: Recall past clinical scenarios from papers above - they repeat patterns
FINAL TIPS
- Every MCQ in this exam is a clinical case - always think "which nerve/artery/structure is at risk here"
- Short notes = 80 marks total across Q3-Q6. This is where the exam is won or lost
- Diagrams = bonus marks - even a rough labeled diagram in short notes gets you extra credit
- Explain Why questions (Q3) - always give a 3-4 line anatomical/physiological reason, not just a one-liner
- The long essay (Q2) follows a structured sub-part pattern - answer each part separately with a heading
- Topics that appeared in RUHS are UNLIKELY to repeat in the exact same form in your exam - focus on adjacent topics
- For Physiology P1, the MCQs heavily test clinical correlation - especially endocrine (Graves, DM, Parkinson, Myasthenia) and neurophysiology
- Start with Q1 MCQs (easy marks, 20 min), then Q2 long essay, then short notes in order
Good luck - 10 days is enough if you stay focused. Anatomy P1 has the most topics so front-load your preparation!
You only considered anatomy paper 1and2 and Physio paper 1 what about Physio paper 2 and biochem paper 1 and 2 in the guide
You're right - I only had the RUHS papers for Anatomy P1, Anatomy P2, and Physiology P1. I don't have the actual RUHS question papers for Physiology Paper 2, Biochemistry Paper 1, and Biochemistry Paper 2 to analyse.
To build an equally accurate guide for those 3 subjects, I need their question papers too - the same way you shared the others.
Could you please share:
- Physiology Paper 2 - the RUHS July 2026 question paper
- Biochemistry Paper 1 - the RUHS July 2026 question paper
- Biochemistry Paper 2 - the RUHS July 2026 question paper
Once you upload those images, I'll analyse them the same way and add complete topic predictions, high-yield lists, and the remaining study days (Days 11-20 covering Physio P2 on Aug 17, Biochem P1 on Aug 19, and Biochem P2 on Aug 21) to your guide.
IMG_2722.jpg
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This is the syllabus for the Marwar university exam now analyze the ruhs paper and predict the paper and possible questions
I can see the syllabus clearly. Now I have everything I need - the RUHS papers + the official Marwar syllabus. Let me build the complete prediction for all 6 papers.
One important note: You shared the syllabus for Anatomy P1, Anatomy P2, and Physiology P1 only. The Physiology P2 and Biochemistry P1 & P2 syllabi are not in these images. However, I can still predict those papers based on standard CBME First MBBS curriculum (NMC 2024), which is the same framework.
COMPLETE MARWAR MEDICAL UNIVERSITY - FIRST MBBS 2026
PAPER-WISE PREDICTION GUIDE (All 6 Papers)
Based on: RUHS July 2026 Papers + Official Marwar/CBME Syllabus
PAPER 1: HUMAN ANATOMY - 10 AUGUST 2026
Syllabus Coverage (Official Marwar):
- General Anatomy (AN1.1-AN7.8)
- Upper Limb (AN8.1-AN13.8)
- Head & Neck (AN26.1-AN43.9)
- Brain/Neuroanatomy (AN56.1-AN64.3)
- Ethics in Anatomy / AETCOM 1.5
RUHS P1 Already Asked (July 2026) - Will NOT repeat:
- Tongue (Long Essay Q2)
- Internal Capsule, Cubital fossa, Deltoid, Thyroid micro/development (Short Notes)
- Lateral medullary syndrome, Otic ganglion, Ulnar nerve in hand (Short Notes)
- Circle of Willis, Styloid apparatus, Dorsal digital expansion, Cadaver as first teacher (Short Notes)
- Explain Why: 1st CMC joint, shoulder dislocation inferior, facial muscles expression, maxillary sinusitis chronic, hypothalamus head ganglion
ANATOMY P1 - PREDICTED PAPER (Marwar Aug 10)
Q1 - MCQs (20×1 = 20 marks) - Predicted Clinical Scenarios:
| # | Clinical Scenario | Answer |
|---|---|---|
| 1 | Patient with wrist drop after fracture mid-shaft humerus | Radial nerve |
| 2 | Winged scapula after mastectomy / axillary dissection | Long thoracic nerve (serratus anterior) |
| 3 | Loss of abduction of arm after shoulder dislocation | Axillary nerve |
| 4 | "Pope's blessing" / unable to make OK sign | Median nerve |
| 5 | Claw hand (ring + little finger) | Ulnar nerve |
| 6 | Carpal tunnel syndrome - which nerve? | Median nerve |
| 7 | Patient cannot extend thumb - which muscle/nerve? | Posterior interosseous nerve (radial) |
| 8 | Fracture anatomical neck of humerus - structure injured | Axillary nerve |
| 9 | Spinal cord hemisection - ipsilateral motor loss + contralateral pain/temp loss | Brown-Sequard |
| 10 | "Cape-like" loss of pain/temp in upper limbs | Syringomyelia |
| 11 | Epidural hematoma - biconvex on CT | Middle meningeal artery |
| 12 | Subdural hematoma after head injury | Bridging veins |
| 13 | Horner's syndrome (ptosis, miosis, anhidrosis) | Cervical sympathetic chain |
| 14 | Parotid tumor - unable to close eye | Facial nerve (CN VII) |
| 15 | Referred otalgia from tongue carcinoma - which nerve? | Lingual nerve / CN V3 |
| 16 | Lesion at internal capsule - what deficit? | Contralateral hemiplegia |
| 17 | Foramen magnum lesion | Accessory nerve / medulla |
| 18 | Eye moves down and out - which nerve palsy? | CN III (oculomotor) |
| 19 | Submandibular gland stone - which duct? | Wharton's duct |
| 20 | Injury to radial nerve in axilla - cannot extend wrist/fingers | High radial nerve palsy |
Q2 - LONG ESSAY (10 marks) - TOP 3 PREDICTIONS:
PREDICTION 1 (Most likely): BRACHIAL PLEXUS
- (a) Formation - roots, trunks, divisions, cords, terminal branches (4 marks)
- (b) Branches from roots and trunks (3 marks)
- (c) Applied anatomy - common injuries and their effects (3 marks)
PREDICTION 2: SHOULDER JOINT
- (a) Articular surfaces and ligaments (3 marks)
- (b) Muscles acting on shoulder joint (3 marks)
- (c) Applied anatomy - why it dislocates inferiorly (4 marks)
PREDICTION 3: CEREBRAL CORTEX / CEREBRAL HEMISPHERES
- (a) Motor and sensory areas (3 marks)
- (b) Speech areas (Broca's and Wernicke's) (3 marks)
- (c) Internal capsule and applied anatomy (4 marks)
Q3 - EXPLAIN WHY (5×3 = 15 marks) - Predicted:
| # | Question | Key Answer Points |
|---|---|---|
| a | Why does radial nerve palsy cause wrist drop? | Radial nerve supplies all extensors of wrist and fingers; paralysis causes unopposed flexion |
| b | Why is the ulnar nerve called the "musician's nerve"? | Supplies intrinsic muscles of hand (interossei, hypothenar) needed for fine movements |
| c | Why does injury to C5-C6 cause Erb's palsy (waiter's tip)? | Upper trunk injury - deltoid/biceps paralysis, limb hangs internally rotated |
| d | Why is the pterion the weakest point of the skull? | Junction of 4 bones, very thin; overlies middle meningeal artery |
| e | Why is the parotid gland painful when inflamed? | Enclosed in tough parotid fascia (deep cervical fascia), no room to expand |
Q4 - SHORT NOTES (4×5 = 20 marks) - Predicted:
| Topic | Key Points to Cover |
|---|---|
| Brachial plexus (if not asked in Q2) | Formation, cords, terminal branches, one injury |
| Elbow joint | Type, articular surfaces, carrying angle, cubitus valgus |
| Carpal tunnel | Boundaries, contents, carpal tunnel syndrome |
| Blood supply of spinal cord | ASA, PSA, sulcocommissural, applied (ASA syndrome) |
Q5 - SHORT NOTES (3×5 = 15 marks) - Predicted:
| Topic | Key Points |
|---|---|
| Median nerve in hand | Counterpart to Ulnar (asked in RUHS) - distribution, thenar muscles, ape thumb |
| Facial nerve | Course, branches, applied - Bell's palsy |
| Meninges and CSF | Three layers, spaces, CSF formation, lumbar puncture |
Q6 - SHORT NOTES (4×5 = 20 marks) - Predicted:
| Topic | Key Points |
|---|---|
| Pterion | Formation, relations, applied - middle meningeal artery |
| Cavernous sinus | Contents, thrombosis, communications |
| Rotator cuff | 4 muscles (SITS), functions, rotator cuff tear |
| Hypothalamus | Functions, nuclei, connections - "head ganglion of ANS" - (Explain Why was asked but Short Note not yet) |
PAPER 2: HUMAN ANATOMY - 12 AUGUST 2026
Syllabus Coverage (Official Marwar):
- Lower Limb (AN14.1-AN20.10)
- Thorax (AN21.1-AN25.9)
- Abdomen (AN44.1-AN55.2)
- General Histology (AN65.1-AN72.1)
- General Embryology & Genetics (AN73.1-AN81.3)
- AETCOM 1.4 - Foundations of Communication
RUHS P2 Already Asked - Will NOT repeat:
- Anal canal (Long Essay)
- Vermiform appendix micro, Left coronary artery, Lesser sac, Adductor canal, Inguinal hernia, Gluteus maximus, Superior mediastinum, Gall bladder, Development of kidney, Lymphatic drainage of stomach, Principles of Communication (Short Notes)
- Explain Why: Cholecystitis referred to shoulder, hepatorenal pouch fluid, foot drop fibula neck, Down syndrome, paradoxical respiration
ANATOMY P2 - PREDICTED PAPER (Marwar Aug 12)
Q1 - MCQs (20×1 = 20 marks) - Predicted:
| # | Clinical Scenario | Answer |
|---|---|---|
| 1 | Medial thigh pain + weak adduction after pelvic fracture | Obturator nerve |
| 2 | Knee unable to flex, sensation back of thigh lost | Sciatic nerve high injury |
| 3 | Footballer with knee injury - locked knee | Medial meniscus (coronary ligament) |
| 4 | ACL injury - positive anterior drawer test | ACL rupture |
| 5 | Varicose veins surgery - medial leg numbness | Saphenous nerve |
| 6 | Cannot dorsiflex foot after hip replacement surgery | Common peroneal nerve |
| 7 | Cannot plantarflex + lost sensation heel | Tibial nerve |
| 8 | Fracture neck of femur in elderly - blood supply lost | Medial circumflex femoral artery |
| 9 | Appendicitis pain starts periumbilical then shifts right iliac fossa | Referred via T10, then peritoneal |
| 10 | Patient with SVC obstruction - dilated veins on chest wall | Azygos system collateral |
| 11 | Right heart failure - right sided pleural effusion - needle placement | 9th intercostal space, mid-axillary |
| 12 | Ventricular septal defect murmur location | 4th intercostal space, left sternal border |
| 13 | Portal hypertension - caput medusae | Paraumbilical vein (portal-systemic) |
| 14 | GERD - which sphincter weak? | Lower esophageal sphincter |
| 15 | Horseshoe kidney - which artery may compress it? | Inferior mesenteric artery |
| 16 | Spina bifida occulta - which vertebra most common? | L5 or S1 |
| 17 | Turner's syndrome karyotype | 45 XO |
| 18 | Trisomy 21 - which chromosome? | Chromosome 21 |
| 19 | At 4th week, embryo has C-shaped curve - which layer forms the heart? | Splanchnic mesoderm / lateral plate |
| 20 | Placenta previa occurs because of abnormal implantation in | Lower uterine segment |
Q2 - LONG ESSAY (10 marks) - TOP 3 PREDICTIONS:
PREDICTION 1 (Most likely): INGUINAL CANAL
- (a) Formation - anterior, posterior walls, roof, floor (4 marks)
- (b) Contents of inguinal canal (3 marks)
- (c) Inguinal hernia - direct vs indirect differences (3 marks)
PREDICTION 2: LIVER
- (a) External features, lobes, surfaces, relations (4 marks)
- (b) Blood supply and bile drainage (3 marks)
- (c) Applied anatomy - portal hypertension, hepatorenal pouch (3 marks)
PREDICTION 3: HEART
- (a) External features, chambers, valves (4 marks)
- (b) Coronary arteries - right and left (3 marks)
- (c) Applied anatomy - coronary artery disease, referred pain (3 marks)
Q3 - EXPLAIN WHY (5×3 = 15 marks) - Predicted:
| # | Question | Key Answer Points |
|---|---|---|
| a | Why does femoral hernia occur more in females? | Wider pelvis → wider femoral ring; no cremasteric mechanism |
| b | Why is the right bronchus more vertical than left? | More vertical = aspirated foreign bodies go to right lower lobe |
| c | Why does appendicitis pain start around umbilicus? | Appendix is midgut (T10 dermatome = periumbilical) - visceral pain |
| d | Why is the left recurrent laryngeal nerve longer than right? | Loops around arch of aorta in thorax; right only loops around subclavian |
| e | Why does trisomy 21 (Down syndrome) cause intellectual disability? | Extra chromosome 21 → excess gene dosage → neuronal development disruption |
Q4 - SHORT NOTES (4×5 = 20 marks) - Predicted:
| Topic | Why Predicted |
|---|---|
| Hip joint | Not asked in RUHS; Lower limb - classic |
| Femoral triangle | Classic lower limb short note |
| Right coronary artery | Left coronary was asked in RUHS - right is the counterpart |
| Kidney (structure + relations) | Development asked in RUHS; structure not yet |
Q5 - SHORT NOTES (3×5 = 15 marks) - Predicted:
| Topic | Why Predicted |
|---|---|
| Meckel's diverticulum | Classic embryology short note - very high yield |
| Portal vein | Tributaries, portal-systemic anastomoses |
| Femoral hernia | Counterpart to inguinal hernia; inguinal was short note in RUHS |
Q6 - SHORT NOTES (4×5 = 20 marks) - Predicted:
| Topic | Why Predicted |
|---|---|
| Pharyngeal arches | MCQ in RUHS P1 (1st arch = mandible/cleft palate) - Short note due |
| Development of uterus | Paramesonephric duct MCQ in RUHS P2; short note likely |
| Popliteal fossa | Lower limb - classic, not yet asked |
| Ureter | Course, constrictions, blood supply, stones |
PAPER 3: PHYSIOLOGY PAPER I - 14 AUGUST 2026
Syllabus Coverage (Official Marwar):
- General Physiology + Biophysics (PY1.1-1.7)
- Nerve Muscle Physiology (PY3.1-3.12)
- Endocrine Physiology (PY8.1-8.7)
- Reproductive Physiology (PY9.1-9.10)
- Neurophysiology / Nervous System (PY10.1-10.20)
- Special Senses (PY11.1-11.7)
- Integrated Physiology: Growth & development + Ageing (PY12.6)
- Temperature regulation (PY12.1-12.2)
- Brain death (PY12.7)
- AETCOM 1.2 - What does it mean to be a patient?
RUHS P1 Already Asked - Will NOT repeat:
- Referred pain (Long Essay)
- Theories of ageing, Metabolic syndrome, Benefits of yoga, Physiological response to cold, Indicators of ovulation, Acromegaly, Impedance matching, UMN vs LMN, Ionic basis of action potential, Androgen resistance syndrome, Responsibilities of physician (Short Notes)
- Explain Why: RBC lysis/Na-K-ATPase, Lambert-Eaton improves with activity, Carbidopa + Levodopa, infertility in undescended testis, tachycardia in hyperthyroidism
PHYSIOLOGY P1 - PREDICTED PAPER (Marwar Aug 14)
Q1 - MCQs (20×1 = 20 marks) - Predicted:
| # | Clinical Scenario | Answer |
|---|---|---|
| 1 | Patient with muscle weakness + fasciculations + absent reflexes + wasting | LMN lesion |
| 2 | Spasticity + hyperreflexia + Babinski positive | UMN lesion |
| 3 | Tetany after thyroidectomy | Hypocalcemia (parathyroid removed) |
| 4 | Acromegaly - excess of which hormone? | Growth hormone (GH) |
| 5 | Cushing's syndrome - which steroid excess? | Cortisol (glucocorticoid) |
| 6 | Patient with bulging eyes + weight loss + heat intolerance | Hyperthyroidism (Graves) - already asked; variant: TSH level = LOW |
| 7 | Addison's disease - skin hyperpigmentation due to? | Excess ACTH/MSH from pituitary |
| 8 | Patient with inability to concentrate urine - lesion at? | ADH deficiency - posterior pituitary (Diabetes insipidus) |
| 9 | Phaeochromocytoma - which hormone? | Adrenaline + noradrenaline |
| 10 | NMJ blocker used in anaesthesia | Succinylcholine / vecuronium (depolarizing vs non-depolarizing) |
| 11 | Which wave on EEG during deep sleep? | Delta waves |
| 12 | Gate control theory of pain - which fibres? | A-beta fibres (large, myelinated) close the gate |
| 13 | Lesion optic tract - which visual field defect? | Contralateral homonymous hemianopia |
| 14 | Noise-induced hearing loss - which part of cochlea? | Basal turn (high frequency) |
| 15 | Patient with amnesia - hippocampus lesion - which memory? | Anterograde memory |
| 16 | Hyperkalemia effect on resting membrane potential | Depolarization (less negative RMP) |
| 17 | G-protein coupled receptor - second messenger | cAMP (adenyl cyclase) |
| 18 | Normal body temperature maintained by | Hypothalamus (thermoregulatory centre) |
| 19 | Spermatogenesis occurs at which temperature? | 2-3°C below body temperature |
| 20 | Menstrual cycle - LH surge causes | Ovulation |
Q2 - LONG ESSAY (10 marks) - TOP 3 PREDICTIONS:
PREDICTION 1 (Most likely): NEUROMUSCULAR JUNCTION
- (a) Structure of NMJ (3 marks)
- (b) Mechanism of neuromuscular transmission (4 marks)
- (c) Applied - Myasthenia Gravis vs Lambert-Eaton syndrome (3 marks)
PREDICTION 2: ACTION POTENTIAL
- (a) Resting membrane potential - ionic basis (3 marks)
- (b) Events of action potential with diagram (4 marks)
- (c) Conduction of action potential (3 marks)
PREDICTION 3: THYROID GLAND PHYSIOLOGY
- (a) Synthesis and secretion of thyroid hormones (4 marks)
- (b) Actions of thyroid hormones (3 marks)
- (c) Applied - Hypothyroidism vs Hyperthyroidism (3 marks)
Q3 - EXPLAIN WHY (5×3 = 15 marks) - Predicted:
| # | Question | Key Answer |
|---|---|---|
| a | Why does cutting the vagus nerve increase heart rate? | Vagus is parasympathetic to SA node; cutting removes its inhibitory tone → tachycardia |
| b | Why is succinylcholine a depolarizing blocker? | Mimics ACh, binds NMJ receptor, causes persistent depolarization (Phase I block) |
| c | Why is calcium important for muscle contraction? | Troponin C binds Ca²⁺ → conformational change → actin-myosin cross-bridge formation |
| d | Why does hypothyroidism cause bradycardia? | T3/T4 upregulates beta receptors and directly increases SA node automaticity; their absence slows HR |
| e | Why is vision sharpest at fovea centralis? | Maximum cone density, no rods; each cone has private pathway to visual cortex |
Q4 - SHORT NOTES (4×5 = 20 marks) - Predicted:
| Topic | Why Predicted |
|---|---|
| Neuromuscular junction (if not in Q2) | MCQ on myasthenia + explain why Lambert-Eaton = NMJ is THE topic |
| Basal ganglia | Parkinson's MCQ in RUHS - short note due |
| Cerebellar functions | Flocculonodular lobe MCQ in RUHS - short note due |
| Menstrual cycle | Reproductive physiology - classic |
Q5 - SHORT NOTES (3×5 = 15 marks) - Predicted:
| Topic | Why Predicted |
|---|---|
| Resting membrane potential | Ionic basis of AP was asked; RMP is the next logical step |
| Graves' disease | MCQ on it in RUHS; short note not yet asked |
| Hypothalamus as thermoregulator | Temperature regulation in syllabus; cold response asked - now hypothalamus |
Q6 - SHORT NOTES (4×5 = 20 marks) - Predicted:
| Topic | Why Predicted |
|---|---|
| Obstructive sleep apnea | MCQ in RUHS (loud snoring case) - short note likely |
| Brain death | Explicitly in syllabus (PY12.7); never asked in RUHS |
| What does it mean to be a patient | AETCOM 1.2 - explicitly in P1 syllabus; not yet asked |
| Cortisol | Adrenal physiology not touched in RUHS P1 |
PAPER 4: PHYSIOLOGY PAPER II - 17 AUGUST 2026
Syllabus (Standard CBME First MBBS - PY Paper 2):
- Blood physiology (PY2.1-2.11): Blood groups, Hemostasis, WBCs, RBCs, Anemia
- Cardiovascular physiology (PY4.1-4.15): Cardiac cycle, ECG, Heart sounds, Regulation of BP
- Respiratory physiology (PY5.1-5.9): Lung volumes, Spirometry, Gas exchange, Respiratory regulation
- Renal physiology (PY6.1-6.11): GFR, Tubular function, Concentration of urine, Micturition
- Gastrointestinal physiology (PY7.1-7.8): Secretions, Motility, Digestion
- Exercise physiology (PY12.3-12.5)
- AETCOM 1.3: What does it mean to be a doctor?
PHYSIOLOGY P2 - PREDICTED PAPER (Marwar Aug 17)
Q1 - MCQs (20×1 = 20 marks) - Predicted:
| # | Clinical Scenario | Answer |
|---|---|---|
| 1 | Blood transfusion reaction - wrong group given - type of hypersensitivity | Type II (cytotoxic) |
| 2 | Universal donor blood group | O negative |
| 3 | Patient with prolonged bleeding time + normal clotting time | Platelet disorder / von Willebrand |
| 4 | Hemophilia A - which factor deficient? | Factor VIII |
| 5 | Iron deficiency anemia - type of RBC | Microcytic hypochromic |
| 6 | Patient with chest pain radiating to left arm + jaw | MI (left coronary territory) |
| 7 | ECG: prolonged PR interval | First degree heart block |
| 8 | Which heart sound = closure of mitral + tricuspid valve? | S1 |
| 9 | Which valve disease gives opening snap? | Mitral stenosis |
| 10 | Spirometry: FEV1/FVC ratio reduced | Obstructive lung disease (asthma/COPD) |
| 11 | Respiratory alkalosis - cause | Hyperventilation |
| 12 | Carbon monoxide poisoning - which Hb parameter changes? | Shifts O2-Hb curve LEFT |
| 13 | GFR marker that is freely filtered, not reabsorbed | Inulin |
| 14 | Loop of Henle - which part is impermeable to water? | Ascending limb (thick) |
| 15 | ADH acts on which nephron segment? | Collecting duct |
| 16 | Peptic ulcer - excess acid - which cell? | Parietal cells (HCl) |
| 17 | Intrinsic factor for B12 absorption - which cell? | Parietal cells |
| 18 | Jaundice + dark urine + pale stools | Obstructive jaundice |
| 19 | Exercise increases heart rate - which reflex? | Bainbridge reflex + muscle mechanoceptors |
| 20 | Normal cardiac output in 70 kg adult | 5 L/min |
Q2 - LONG ESSAY (10 marks) - TOP 3 PREDICTIONS:
PREDICTION 1 (Most likely): CARDIAC CYCLE
- (a) Events of cardiac cycle - pressure, volume changes with diagram (4 marks)
- (b) Heart sounds - mechanism (3 marks)
- (c) Starling's law of the heart (3 marks)
PREDICTION 2: REGULATION OF BLOOD PRESSURE
- (a) Short-term regulation - baroreceptors, chemoreceptors (4 marks)
- (b) Long-term regulation - RAAS, ADH (3 marks)
- (c) Hypertension - applied (3 marks)
PREDICTION 3: RENAL REGULATION
- (a) GFR - factors affecting (3 marks)
- (b) Tubular reabsorption and secretion (4 marks)
- (c) Regulation of urine concentration (3 marks)
Q3 - EXPLAIN WHY (5×3 = 15 marks) - Predicted:
| # | Question | Key Answer |
|---|---|---|
| a | Why does left heart failure cause pulmonary edema? | LV failure → raised LA pressure → raised pulmonary venous pressure → fluid into lung |
| b | Why is CO poisoning dangerous even at low concentrations? | CO has 200x higher affinity for Hb than O2; forms carboxyhemoglobin |
| c | Why does loop diuretic cause hypokalemia? | Furosemide blocks Na-K-2Cl cotransporter → increased Na delivery to distal tubule → aldosterone-mediated K loss |
| d | Why is inulin used to measure GFR? | Freely filtered, not reabsorbed, not secreted, not metabolized |
| e | Why does high altitude cause polycythemia? | Low PaO2 → hypoxia → erythropoietin release from kidney → increased RBC production |
Q4 - SHORT NOTES (4×5 = 20 marks) - Predicted:
| Topic |
|---|
| ECG - waves, intervals, segments |
| Erythropoiesis (stages + regulation) |
| JGA and renin-angiotensin-aldosterone system |
| Surfactant (type II pneumocyte, function, deficiency in newborn) |
Q5 - SHORT NOTES (3×5 = 15 marks) - Predicted:
| Topic |
|---|
| Hemostasis and platelet plug formation |
| Spirometry - lung volumes and capacities |
| Gastric secretion (HCl mechanism, pepsin, phases) |
Q6 - Short Notes (4×5 = 20 marks) - Predicted:
| Topic |
|---|
| Starling's law of heart |
| Blood-brain barrier (overlap with Anatomy) |
| What does it mean to be a doctor (AETCOM 1.3) |
| Exercise physiology (cardiovascular + respiratory changes) |
PAPER 5: BIOCHEMISTRY PAPER I - 19 AUGUST 2026
Syllabus (Standard CBME First MBBS Biochemistry P1):
- Carbohydrate metabolism (glycolysis, TCA, gluconeogenesis, glycogen metabolism)
- Lipid metabolism (fatty acid oxidation, synthesis, lipoproteins, ketone bodies)
- Protein and amino acid metabolism (transamination, urea cycle, amino acid catabolism)
- Enzyme kinetics (Michaelis-Menten, inhibition, isoenzymes)
- Vitamins (fat-soluble: A, D, E, K; water-soluble: B-complex, C)
- Biological oxidation (ETC, oxidative phosphorylation)
- Integration of metabolism
BIOCHEMISTRY P1 - PREDICTED PAPER (Marwar Aug 19)
Q1 - MCQs (20×1 = 20 marks) - Predicted:
| # | Clinical Scenario | Answer |
|---|---|---|
| 1 | Diabetic patient - ketoacidosis - which bodies elevated? | Acetoacetate, Beta-hydroxybutyrate, Acetone |
| 2 | Night blindness - which vitamin deficiency? | Vitamin A |
| 3 | Rickets in child - which vitamin? | Vitamin D (cholecalciferol) |
| 4 | Scurvy - inability to synthesize which amino acid modification? | Hydroxyproline (collagen) - Vitamin C required |
| 5 | Bleeding disorder + newborn - which vitamin deficiency? | Vitamin K |
| 6 | Enzyme that commits glucose to glycolysis? | Phosphofructokinase-1 (PFK-1) |
| 7 | Phenylketonuria - which enzyme deficient? | Phenylalanine hydroxylase |
| 8 | Alkaptonuria - dark urine on standing - enzyme deficient | Homogentisate oxidase |
| 9 | Maple syrup urine disease - amino acids elevated | Leucine, Isoleucine, Valine (branched chain) |
| 10 | Rate-limiting step of cholesterol synthesis? | HMG-CoA reductase |
| 11 | Statins mechanism | HMG-CoA reductase inhibitors |
| 12 | Urea cycle - where does it occur? | Liver (mitochondria + cytosol) |
| 13 | NAD+ is required for which step of TCA? | Isocitrate dehydrogenase, Alpha-KG dehydrogenase, Malate dehydrogenase |
| 14 | Thiamine deficiency - which TCA enzyme affected? | Alpha-ketoglutarate dehydrogenase |
| 15 | Cori cycle - between which organs? | Muscle and liver |
| 16 | NADPH is produced by which pathway? | HMP shunt (Pentose phosphate pathway) |
| 17 | G6PD deficiency + hemolytic anemia after eating fava beans | G6PD deficiency → low NADPH → cannot protect RBC from oxidative stress |
| 18 | Fatty acid synthesis occurs in? | Cytosol (NADPH, acetyl CoA) |
| 19 | Which lipoprotein carries cholesterol from tissues to liver? | HDL (reverse cholesterol transport) |
| 20 | Km value of an enzyme represents | Substrate concentration at half-maximal velocity |
Q2 - LONG ESSAY (10 marks) - TOP 3 PREDICTIONS:
PREDICTION 1 (Most likely): GLYCOLYSIS
- (a) Steps of glycolysis with enzymes (5 marks)
- (b) Energy yield from glycolysis (2 marks)
- (c) Applied - Glycolysis in RBCs; anaerobic glycolysis (3 marks)
PREDICTION 2: TCA CYCLE
- (a) Steps with enzymes, coenzymes (5 marks)
- (b) Energy yield (2 marks)
- (c) Amphibolic nature, anaplerotic reactions (3 marks)
PREDICTION 3: ELECTRON TRANSPORT CHAIN
- (a) Components - complexes I-IV (4 marks)
- (b) ATP synthesis - chemiosmotic theory (3 marks)
- (c) Inhibitors and uncouplers (3 marks)
Q3 - EXPLAIN WHY (5×3 = 15 marks) - Predicted:
| # | Question |
|---|---|
| a | Why do RBCs only use glycolysis for energy? (no mitochondria) |
| b | Why does diabetic ketoacidosis develop? (excess fatty acid oxidation → ketone bodies) |
| c | Why does Vitamin C deficiency cause scurvy? (hydroxylation of proline/lysine in collagen) |
| d | Why is G6PD deficiency associated with hemolytic anemia? (cannot regenerate NADPH → oxidative damage) |
| e | Why is PKU treated with low phenylalanine diet? (excess Phe → toxic metabolites → brain damage) |
Q4 - Short Notes (4×5 = 20):
| Topic |
|---|
| Urea cycle (steps + enzymes) |
| HMG-CoA reductase and cholesterol synthesis |
| Vitamin D - synthesis, functions, deficiency |
| Isoenzymes - LDH and CK in MI diagnosis |
Q5 - Short Notes (3×5 = 15):
| Topic |
|---|
| Ketone bodies - synthesis + utilization + ketoacidosis |
| Cori cycle |
| Enzyme inhibition - competitive vs non-competitive |
Q6 - Short Notes (4×5 = 20):
| Topic |
|---|
| HMP shunt (Pentose phosphate pathway) - importance |
| Vitamin K - functions, deficiency, antagonists (warfarin) |
| Phenylketonuria - metabolic defect + treatment |
| Lipoproteins - classification, functions (LDL, HDL, VLDL) |
PAPER 6: BIOCHEMISTRY PAPER II - 21 AUGUST 2026
Syllabus (Standard CBME First MBBS Biochemistry P2):
- DNA structure and replication
- RNA and transcription
- Protein synthesis and translation
- Molecular biology techniques (PCR, Southern blot, etc.)
- Acid-base balance
- Plasma proteins
- Hemoglobin - structure, variants, derivatives
- Porphyrin metabolism
- Iron metabolism
- Mineral metabolism (Ca, Mg, P)
- Water and electrolyte balance
- Clinical biochemistry - LFT, KFT, thyroid function tests
BIOCHEMISTRY P2 - PREDICTED PAPER (Marwar Aug 21)
Q1 - MCQs (20×1 = 20 marks) - Predicted:
| # | Clinical Scenario | Answer |
|---|---|---|
| 1 | Sickle cell anemia - which amino acid substitution? | Glutamic acid → Valine at position 6 of beta chain |
| 2 | Jaundice in newborn - unconjugated hyperbilirubinemia - treatment | Phototherapy (converts bilirubin to water-soluble form) |
| 3 | Lead poisoning - which enzyme in heme synthesis inhibited? | ALA dehydratase + Ferrochelatase |
| 4 | Patient with serum protein electrophoresis - M-band - diagnosis | Multiple myeloma (monoclonal Ig) |
| 5 | Which plasma protein is the main transporter of fatty acids? | Albumin |
| 6 | Acute MI - which enzyme elevated first? | Troponin T/I (most specific); first to rise = Troponin within 3-6 hrs |
| 7 | Metabolic acidosis with increased anion gap | DKA / lactic acidosis / methanol poisoning |
| 8 | Respiratory alkalosis compensated - which change? | Kidneys excrete HCO3- |
| 9 | Okazaki fragments in DNA replication - in which strand? | Lagging strand |
| 10 | Which RNA is the adaptor molecule in translation? | tRNA |
| 11 | PCR requires which enzyme? | Taq polymerase |
| 12 | Southern blot - detects? | DNA |
| 13 | Aminoglycosides cause deafness - mechanism? | Inhibit 30S ribosome (prokaryotic) - renal + ototoxic |
| 14 | Rifampicin mechanism | Inhibits bacterial RNA polymerase |
| 15 | Which bond holds base pairs in DNA? | Hydrogen bonds |
| 16 | Hypercalcemia - causes? | Hyperparathyroidism, malignancy, Vit D toxicity |
| 17 | Wilson's disease - which mineral? | Copper (ceruloplasmin low) |
| 18 | Hemochromatosis - which mineral? | Iron (excess) |
| 19 | Normal serum albumin level | 3.5-5 g/dL |
| 20 | Which immunoglobulin crosses placenta? | IgG |
Q2 - LONG ESSAY (10 marks) - TOP 3 PREDICTIONS:
PREDICTION 1 (Most likely): DNA REPLICATION
- (a) Semi-conservative replication - enzymes involved (4 marks)
- (b) Steps - initiation, elongation, termination (3 marks)
- (c) Applied - PCR technique (3 marks)
PREDICTION 2: HEMOGLOBIN
- (a) Structure of hemoglobin - types (4 marks)
- (b) Oxygen dissociation curve - factors shifting it (3 marks)
- (c) Hemoglobin variants - HbS, HbA1c, HbF (3 marks)
PREDICTION 3: ACID-BASE BALANCE
- (a) Buffer systems of blood (3 marks)
- (b) Types of acid-base disorders with examples (4 marks)
- (c) Compensation mechanisms (3 marks)
Q3 - Explain Why (5×3 = 15 marks) - Predicted:
| # | Question |
|---|---|
| a | Why does sickle cell HbS polymerize in deoxygenated state? |
| b | Why is fetal Hb (HbF) shifted left on oxygen dissociation curve? |
| c | Why does jaundice appear in G6PD deficiency after eating fava beans? |
| d | Why is albumin important for maintaining oncotic pressure? |
| e | Why is anion gap elevated in DKA? |
Q4 - Short Notes (4×5 = 20):
| Topic |
|---|
| Transcription - steps and types of RNA |
| Porphyria - acute intermittent porphyria |
| Iron metabolism - absorption, transport, storage |
| Bilirubin metabolism - conjugation, excretion |
Q5 - Short Notes (3×5 = 15):
| Topic |
|---|
| Plasma proteins - types and functions |
| Restriction endonucleases |
| Myoglobin vs Hemoglobin (oxygen binding) |
Q6 - Short Notes (4×5 = 20):
| Topic |
|---|
| Translation - steps + antibiotics that inhibit it |
| Calcium metabolism and regulation |
| Liver function tests - what they measure and significance |
| Oncogenes and tumor suppressor genes (basic molecular biology) |
REVISED 20-DAY STUDY SCHEDULE
| Day | Date | Subject | Focus |
|---|---|---|---|
| 1 | 30 Jul | Anatomy P1 | Upper limb - Brachial plexus, nerve injuries |
| 2 | 31 Jul | Anatomy P1 | Head & Neck + Neuroanatomy |
| 3 | 1 Aug | Anatomy P1 | Lower limb (P1 portion) + spinal cord |
| 4 | 2 Aug | Anatomy P1 | Revision + mock short notes |
| 5 | 3 Aug | Anatomy P2 | Abdomen - Inguinal canal, liver, portal circulation |
| 6 | 4 Aug | Anatomy P2 | Thorax - Heart, mediastinum, lungs |
| 7 | 5 Aug | Anatomy P2 | Lower limb (P2) + Embryology + Histology |
| 8 | 6 Aug | Anatomy P2 | Revision + mock answers |
| 9 | 7 Aug | Physio P1 | NMJ, Action potential, Nerve muscle |
| 10 | 8 Aug | Physio P1 | Neurophysiology + Special senses |
| 11 | 9 Aug | Physio P1 | Endocrine + Reproductive + Revision |
| 12 | 10 Aug | EXAM: Anatomy P1 | Light revision morning only |
| 13 | 11 Aug | Physio P2 | Cardiovascular physiology - Cardiac cycle, ECG, BP |
| 14 | 12 Aug | EXAM: Anatomy P2 | Light revision morning only |
| 15 | 13 Aug | Physio P2 | Blood + Respiratory + Renal |
| 16 | 14 Aug | EXAM: Physio P1 | Light revision morning only |
| 17 | 15 Aug | Physio P2 | GIT + Revision |
| 18 | 16 Aug | Biochemistry | Carbohydrate metabolism (Glycolysis, TCA, ETC) |
| 19 | 17 Aug | EXAM: Physio P2 | Light revision morning only + Biochem afternoon |
| 20 | 18 Aug | Biochemistry | Lipids + Proteins + Vitamins |
| 21 | 19 Aug | EXAM: Biochem P1 | Light revision morning + Biochem P2 afternoon |
| 22 | 20 Aug | Biochemistry P2 | DNA/RNA, Hemoglobin, Acid-Base, Plasma proteins |
| 23 | 21 Aug | EXAM: Biochem P2 | Light revision morning |
THE GOLDEN RULES FOR ALL 6 PAPERS
- Topics from RUHS July 2026 will NOT repeat in the same form - use them to predict the adjacent/complementary topic
- Every MCQ is clinical - practice thinking "which structure/mechanism explains this patient's symptoms"
- Short notes formula: Definition → Key points (5-6) → Diagram → Applied/Clinical significance
- Explain Why formula: One clear mechanism in 4-5 lines - use words like "because," "therefore," "resulting in"
- For Biochem: Focus on metabolic disorders (PKU, G6PD, DKA) - these are the clinical MCQ favourites
- For Physio P2: Cardiac cycle + ECG + BP regulation are the three long essay possibilities - prepare all three
- AETCOM topics (cadaver as teacher, principles of communication, being a patient/doctor) get 5 marks each - easy marks, prepare a standard answer
This is your complete, syllabus-mapped, RUHS-based prediction guide for all 6 papers. Good luck!
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