Mechanism of labor
labor AND physiology
mechanism of labour cardinal movements fetal head WHO obstetric labour physiology
https://www.ncbi.nlm.nih.gov/books/NBK544290
Some texts list descent before flexion, while others describe flexion before descent because these movements overlap in real labor.
Mg So4 dose in pregnancy
magnesium sulfate pregnancy eclampsia neuroprotection
WHO magnesium sulfate pre-eclampsia eclampsia regimen 4 g 5 g maintenance guideline
| Indication | Common IV regimen |
|---|---|
| Severe pre-eclampsia or eclampsia - prevention/treatment of seizures | Loading: 4-6 g IV over 20-30 min. Maintenance: 1-2 g/hour by continuous IV infusion. Continue for 24 hours after delivery or the last seizure, whichever is later. |
| Eclampsia with recurrent seizure | Give an additional 2 g IV slowly over 5-10 min while assessing airway and toxicity. |
| Fetal neuroprotection before anticipated early preterm birth - commonly <32 weeks | A common protocol is 4 g IV over 20-30 min, then 1 g/hour IV until birth or for up to 24 hours. Exact gestational threshold and stop/restart rules follow local obstetric protocol. |
| Pritchard regimen - where infusion pumps are unavailable | 4 g IV slowly plus 10 g IM (5 g in each buttock), then 5 g IM every 4 hours in alternate buttocks. |
Td bvaccine
tetanus diphtheria vaccination pregnancy
WHO tetanus diphtheria Td vaccination pregnancy schedule previously unimmunized
| Dose | Timing |
|---|---|
| Td-1 | At first antenatal visit or as early as possible in pregnancy |
| Td-2 | At least 4 weeks after Td-1, and ideally at least 2 weeks before delivery |
| Td-3 | 6-12 months after Td-2, or in the next pregnancy |
| Td-4 | 1-5 years after Td-3 |
| Td-5 | 1-10 years after Td-4 |
Antra and chaya
India Antara injectable contraceptive Chhaya centchroman family planning official Ministry Health
centchroman contraception
site:nhm.gov.in Antara injectable contraceptive Chhaya centchroman dosage 150 mg 60 mg
| Feature | Antara | Chhaya |
|---|---|---|
| Generic drug | Depot medroxyprogesterone acetate (DMPA) | Centchroman / Ormeloxifene |
| Type | Progestogen-only injectable contraceptive | Non-hormonal, non-steroidal oral contraceptive |
| Dose | 150 mg deep IM injection | 30 mg tablet orally |
| Frequency | Every 3 months (90 days) | Twice weekly for first 3 months, then once weekly |
| Main action | Inhibits ovulation, thickens cervical mucus, makes endometrium unsuitable for implantation | Selective estrogen receptor modulator. Produces anti-estrogenic action in uterus, making implantation unlikely |
| Major benefit | Very effective, private, no daily pill | Weekly pill, non-hormonal, suitable during breastfeeding |
| Common effects | Irregular bleeding, amenorrhea, weight change, delayed return of fertility after stopping | Delayed or irregular menses, sometimes prolonged cycles |
Drugs used in obg with dosage
Which drug group do you want first with exam-style doses?
Some texts list descent before flexion, while others describe flexion before descent because these movements overlap in real labor.
| Indication | Common IV regimen |
|---|---|
| Severe pre-eclampsia or eclampsia - prevention/treatment of seizures | Loading: 4-6 g IV over 20-30 min. Maintenance: 1-2 g/hour by continuous IV infusion. Continue for 24 hours after delivery or the last seizure, whichever is later. |
| Eclampsia with recurrent seizure | Give an additional 2 g IV slowly over 5-10 min while assessing airway and toxicity. |
| Fetal neuroprotection before anticipated early preterm birth - commonly <32 weeks | A common protocol is 4 g IV over 20-30 min, then 1 g/hour IV until birth or for up to 24 hours. Exact gestational threshold and stop/restart rules follow local obstetric protocol. |
| Pritchard regimen - where infusion pumps are unavailable | 4 g IV slowly plus 10 g IM (5 g in each buttock), then 5 g IM every 4 hours in alternate buttocks. |
| Dose | Timing |
|---|---|
| Td-1 | At first antenatal visit or as early as possible in pregnancy |
| Td-2 | At least 4 weeks after Td-1, and ideally at least 2 weeks before delivery |
| Td-3 | 6-12 months after Td-2, or in the next pregnancy |
| Td-4 | 1-5 years after Td-3 |
| Td-5 | 1-10 years after Td-4 |
| Feature | Antara | Chhaya |
|---|---|---|
| Generic drug | Depot medroxyprogesterone acetate (DMPA) | Centchroman / Ormeloxifene |
| Type | Progestogen-only injectable contraceptive | Non-hormonal, non-steroidal oral contraceptive |
| Dose | 150 mg deep IM injection | 30 mg tablet orally |
| Frequency | Every 3 months (90 days) | Twice weekly for first 3 months, then once weekly |
| Main action | Inhibits ovulation, thickens cervical mucus, makes endometrium unsuitable for implantation | Selective estrogen receptor modulator. Produces anti-estrogenic action in uterus, making implantation unlikely |
| Major benefit | Very effective, private, no daily pill | Weekly pill, non-hormonal, suitable during breastfeeding |
| Common effects | Irregular bleeding, amenorrhea, weight change, delayed return of fertility after stopping | Delayed or irregular menses, sometimes prolonged cycles |
Breastcare steps
breastfeeding nipple care
WHO breastfeeding breast care nipple care hygiene guidance
Like stroking shaking squuezing
antenatal breast care steps stroking shaking squeezing nipples