Here is a breakdown of all three cases:
Case 1 - Acute Pancreatitis covers the full clinical scenario of gallstone pancreatitis in a middle-aged woman, with questions on the Atlanta diagnostic criteria, pathophysiology (trypsin auto-activation cascade), severity scoring (Ranson/BISAP/APACHE II/CTSI), management (Lactated Ringer's, no prophylactic antibiotics, ERCP only for cholangitis), and complications including the mechanism of hypocalcemia via fat saponification.
Case 2 - Hartnup Disease covers the pediatric presentation of photosensitive pellagra-like rash + cerebellar ataxia + neuropsychiatric features, the SLC6A19 gene defect and B⁰ transporter mechanism, why plasma amino acids are normal but urine shows neutral aminoaciduria, the tryptophan-to-niacin pathway blockade, and treatment with nicotinamide + high-protein diet.
Case 3 - MCAD Deficiency covers the classic infant with hypoketotic hypoglycemia during fasting/illness, the FAD-dependent beta-oxidation block at medium-chain length, the ACADM c.985A>T mutation, why absent ketones with low glucose is the diagnostic fingerprint, how tandem MS/MS newborn screening (elevated C8-acylcarnitine) detects it, and management by avoiding fasting and IV dextrose during crises.
The summary table at the end is a useful revision tool for the exam. Let me know if you want more cases, MCQs, or deeper detail on any specific topic.