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emergency drugs used in gynecology obstetrics
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gynecological emergency medications management
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The retrieval didn't return gynecology-specific results, so I'll provide a comprehensive answer from medical knowledge.
Emergency Drugs in Gynecology
Here is a categorized list of key drugs used in gynecological emergencies:
1. Obstetric/Gynecologic Hemorrhage (PPH & Bleeding Emergencies)
| Drug | Use | Route |
|---|---|---|
| Oxytocin (Syntocinon) | Uterine atony, PPH prevention/treatment | IV/IM |
| Ergometrine (Ergot alkaloid) | Uterine atony, postpartum hemorrhage | IM/IV |
| Carboprost (15-methyl PGF2α / Hemabate) | Refractory uterine atony | IM |
| Misoprostol (PGE1) | PPH when IV access not available | Sublingual/Rectal |
| Tranexamic Acid | Antifibrinolytic, reduces blood loss | IV |
2. Eclampsia & Severe Pre-eclampsia
| Drug | Use | Route |
|---|---|---|
| Magnesium Sulfate (MgSO₄) | Seizure prophylaxis & treatment in eclampsia | IV/IM |
| Hydralazine | Acute severe hypertension | IV |
| Labetalol | Acute severe hypertension | IV |
| Nifedipine | Acute severe hypertension | Oral/Sublingual |
| Calcium Gluconate | Antidote for MgSO₄ toxicity | IV |
| Diazepam | Eclamptic seizure (if MgSO₄ unavailable) | IV |
3. Ectopic Pregnancy
| Drug | Use | Route |
|---|---|---|
| Methotrexate | Medical management of unruptured ectopic pregnancy | IM |
4. Sepsis / Septic Abortion / Pelvic Infection
| Drug | Use | Route |
|---|---|---|
| Ceftriazone + Metronidazole | Pelvic inflammatory disease / Tubo-ovarian abscess | IV |
| Piperacillin-Tazobactam | Broad-spectrum coverage in sepsis | IV |
| Gentamicin | Part of septic abortion regimen | IV |
| Clindamycin | Anaerobic coverage (PID protocol) | IV |
5. Ovarian Hyperstimulation Syndrome (OHSS)
| Drug | Use | Route |
|---|---|---|
| Albumin | Volume expansion in severe OHSS | IV |
| Cabergoline | OHSS prevention (reduces VEGF) | Oral |
| Heparin (LMWH) | Thromboprophylaxis in OHSS | SC |
6. Tocolysis (Preterm Labor Emergency)
| Drug | Use | Route |
|---|---|---|
| Nifedipine | Tocolysis (first-line) | Oral |
| Atosiban | Oxytocin receptor antagonist tocolytic | IV |
| Terbutaline | Short-term tocolysis | SC/IV |
| Indomethacin | Tocolysis (<32 weeks) | Oral/Rectal |
7. Anaphylaxis (Drug Reactions in Gynecology Settings)
| Drug | Use | Route |
|---|---|---|
| Epinephrine (Adrenaline) | Anaphylaxis | IM (thigh) |
| Hydrocortisone | Adjunct in anaphylaxis/adrenal crisis | IV/IM |
| Chlorpheniramine | Antihistamine | IV |
8. Cervical Ripening / Induction
| Drug | Use | Route |
|---|---|---|
| Dinoprostone (PGE2) | Cervical ripening | Vaginal gel/insert |
| Misoprostol | Induction of labour | Oral/Vaginal |
| Mifepristone | Cervical priming, medical abortion | Oral |
Key mnemonics to remember:
- Uterotonic drugs: Oxytocin, Ergometrine, Carboprost, Misoprostol (O-E-C-M)
- Eclampsia: MgSO₄ is first-line; always have Calcium Gluconate as antidote ready
Let me know if you want more detail on any specific drug or emergency category.
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