Im final year medicine student I'm preparing for my psm exam be a professional teacher and prepare me for exam topic name family planning and contraceptive methods for 20 marks
CONTRACEPTIVE METHODS
├── I. SPACING METHODS
│ ├── 1. Barrier Methods
│ │ ├── (a) Physical methods
│ │ ├── (b) Chemical methods
│ │ └── (c) Combined methods
│ ├── 2. Intra-uterine Devices (IUDs)
│ ├── 3. Hormonal Methods
│ ├── 4. Post-conceptional Methods
│ └── 5. Miscellaneous (Natural methods)
│
└── II. TERMINAL METHODS
├── 1. Male Sterilization (Vasectomy)
└── 2. Female Sterilization (Tubectomy)
| Advantages | Disadvantages |
|---|---|
| Easily available, inexpensive | May slip off or tear with incorrect use |
| No side-effects | Interferes with sexual sensation |
| No medical supervision required | Requires motivation at every coitus |
| Protection against STDs/HIV | - |
| Light, compact, disposable | - |
| Generation | Type | Examples |
|---|---|---|
| 1st generation | Non-medicated / Inert | Lippes Loop |
| 2nd generation | Copper-releasing | Cu-T-200B, Cu-T-380A, Cu-T-220C |
| 3rd generation | Hormone-releasing | Progestasert (progesterone), Mirena (LNG-IUS) |

| Device | Pregnancy rate (%) | Expulsion rate (%) |
|---|---|---|
| Lippes Loop | 3 | 12-20 |
| Cu-7 | 2-3 | 6 |
| TCu-200 | 3 | 8 |
| TCu-380A | 0.5-0.8 | 5 |
| Progesterone IUD | 1.3-1.6 | 2.7 |
| Levonorgestrel IUD | 0.2 | 6 |
Pearl Index = (Total accidental pregnancies / Total months of exposure) × 1200
| Method | Failure Rate (per 100 WY) |
|---|---|
| No contraception | ~85 |
| COC pill (perfect use) | 0.1-0.5 |
| DMPA injection | 0.3 |
| LNG-IUS | 0.2 |
| Implant (Norplant) | 0.05-0.09 |
| Cu-T-380A | 0.5-0.8 |
| Condom | 2-14 |
| Diaphragm (with spermicide) | 2-20 |
| Spermicides alone | 20-25 |
| LAM (all criteria met) | <2 |
| Rhythm method | 14-47 |
| Coitus interruptus | 15-20 |
| Vasectomy | 0.15 |
| Tubectomy (Pomeroy) | 0.5 |
| Question Pattern | Key Answer |
|---|---|
| Contraception under NHP | Cu-T-380A (from 2002); NIRODH; DMPA |
| IUD generations | 1st=inert (Lippes); 2nd=copper (CuT); 3rd=hormonal (LNG-IUS) |
| Most effective reversible method | Implants (Norplant) / LNG-IUS |
| Most effective OC | Combined Oral Pill |
| OC in lactation | Progestogen-only pill (POP) |
| When is vasectomy "sterile"? | After 30 ejaculations + confirmed aspermia |
| Pearl Index formula | (Pregnancies/Months of exposure) x 1200 |
| Emergency contraception window | LNG: 72h; UPA: 120h; Cu-IUD: 5 days |
| LAM criteria | <6 months + exclusive BF + amenorrhoea |
| Fertile period formula | Shortest cycle -18; Longest cycle -11 |
| IUD interval insertion time | Within 10 days of period (ideally day 2) |
| Postpartum tubectomy | Minilaparotomy within 7 days |
| Most common IUD side effect | Increased menstrual bleeding |
| NSV stands for | No Scalpel Vasectomy |
Anc detail explanation with mnemonics for 20 marks
| Letter | Objective |
|---|---|
| P | Promote, protect and maintain health of the mother during pregnancy |
| R | Reduce maternal and infant mortality and morbidity |
| F | Foresee complications and prevent them |
| R | Remove anxiety and dread associated with delivery |
| A | Attend to under-fives accompanying the mother |
| T | Teach the mother - child care, nutrition, hygiene, sanitation |
| I | Identify ("detect") high-risk cases for special attention |
| M | Make her aware of family planning needs |
| Visit | Timing | Purpose |
|---|---|---|
| 1st visit | Within 12 weeks (as soon as pregnancy suspected) | Registration + 1st antenatal check-up + history |
| 2nd visit | 14 - 26 weeks | Blood tests, Hb, anomaly scan |
| 3rd visit | 28 - 34 weeks | BP, presentation, fetal growth |
| 4th visit | 36 weeks to term | Final check, delivery planning |
"Register her early, check her often" - Early registration = within first trimester (before 12 weeks)
| Letter | Component |
|---|---|
| H | History - complete obstetric, medical, family history |
| E | Examination - general + abdominal + pelvic |
| A | Anemia assessment + Iron/Folic acid supplementation |
| L | Lab investigations |
| B | BP monitoring for pre-eclampsia |
| I | Immunization - Tetanus Toxoid |
| T | Teaching/Counselling - nutrition, hygiene, birth preparedness |
| E | Early identification of high-risk cases |
| Parameter | Significance |
|---|---|
| Height | <140 cm in primi → high risk (small pelvis) |
| Weight | Baseline + gain monitoring (normal gain: 10-12 kg total) |
| Blood Pressure | Detect pre-eclampsia (BP ≥ 140/90 mmHg) |
| Pallor | Detect anaemia |
| Oedema | Pre-eclampsia, nutritional deficiency |
| Respiratory rate | Detect respiratory problems |
| Trimester | What to Assess |
|---|---|
| 1st trimester | Uterine size for gestational age |
| 2nd trimester | Fundal height, fetal heart sounds (FHS from 20 wk with fetoscope, 12 wk with Doppler) |
| 3rd trimester | Fundal height, presentation, lie, position, engagement, FHS |
| Test | Purpose |
|---|---|
| H - Haemoglobin estimation | Detect anaemia |
| U - Urine albumin and sugar | Pre-eclampsia, gestational diabetes |
| R - Rapid malaria test | Malaria (endemic zones) |
| B - Blood group (ABO + Rh) | At PHC |
| Test | Purpose |
|---|---|
| S - Syphilis (VDRL/RPR) | Congenital syphilis prevention |
| T - TB skin test | Detect TB |
| V - VDRL + VIH (HIV) testing | PPTCT programme |
| Blood sugar | Gestational diabetes |
| HBsAg | Hepatitis B (for newborn prophylaxis) |
At every visit: Hb estimation + Urine albumin/sugar + BP + Weight + Abdominal examination
| Drug | Dose | Duration |
|---|---|---|
| Folic acid alone | 5 mg/day (or 400 µg periconceptionally) | Peri-conception - 1st trimester (prevents Neural Tube Defects) |
| IFA (Iron 100 mg + Folic acid 500 µg) | 1 tablet/day | From 12 weeks throughout pregnancy |
| Post-delivery | Continue IFA for 180 days postpartum | Under WIFS/RCH programme |
| Situation | Schedule |
|---|---|
| Unimmunized / Unknown | TT-1: as early as possible in pregnancy; TT-2: 4 weeks after TT-1 |
| Previously received 2 TT doses (within 3 years) | Booster dose only |
| Completely immunized (5 doses childhood + 2 previous TT) | One booster |
| Dose | Timing |
|---|---|
| TT-1 | At 1st ANC visit (or early as possible, ideally 16 weeks) |
| TT-2 | 4 weeks after TT-1 (ideally at ~20 weeks) |
| TT Booster | If immunized in previous pregnancy within 3 years |
| Risk Factor | Detail |
|---|---|
| E - Elderly primi | Age ≥ 30 years at first pregnancy |
| S - Short statured primi | Height ≤ 140 cm |
| M - Malpresentation | Breech, transverse lie |
| A - APH / Abortion | Antepartum haemorrhage, threatened abortion, previous abortions |
| P - Pre-eclampsia / eclampsia | BP ≥ 140/90 + proteinuria |
| 3 - 3 or more spontaneous consecutive abortions | |
| Olds - Elderly grandmultipara | Risk of atonic PPH, malpresentations |
| P - Previous CS / instrumental delivery / still-birth / IUD / MRP | |
| A - Anaemia | Hb <11 g/dL (mild), <7 g/dL (severe) |
| S - Systemic diseases | CVD, renal disease, DM, TB, malaria, HIV |
| T - Twins / hydramnios + Treatment for infertility | |
| + | Prolonged pregnancy (>14 days post EDD) |
| Grade | Hb Level | Management |
|---|---|---|
| Normal | ≥ 11 g/dL | Routine IFA |
| Mild anaemia | 10-10.9 g/dL | Double IFA + diet |
| Moderate anaemia | 7-10 g/dL | IFA + investigate + treat underlying cause |
| Severe anaemia | < 7 g/dL | Hospitalize, consider blood transfusion |
| Very severe | < 4 g/dL | Emergency blood transfusion |
| Letter | Advice |
|---|---|
| D | Diet - increase calorie intake by 350 kcal/day, protein-rich diet, green leafy vegetables |
| R | Rest - at least 2 hours rest in afternoon; avoid strenuous work |
| I | Institutional delivery - encourage, explain JSY scheme benefits |
| B | Breastfeeding - antenatal breast preparation, advice on exclusive BF |
| S | Stop smoking/alcohol/tobacco - teratogenic risks |
| A | Awareness of danger signs (see below) |
| F | Family planning - post-delivery contraception counselling |
| E | Exercise/Personal hygiene - light walking, dental care, bowel habits |
| Letter | Danger Sign |
|---|---|
| S | Severe headache / visual disturbances / convulsions (eclampsia) |
| H | High fever |
| E | Excessive vomiting |
| B | Bleeding per vagina (APH) |
| L | Labour pains before 37 weeks (preterm labour) |
| E | Edema of face/hands (pre-eclampsia) |
| E | Escape of fluid (PROM - Premature Rupture of Membranes) |
| D | Decreased / absent fetal movements |
Any danger sign = IMMEDIATE REFERRAL
| Scheme | Full Name | Benefit |
|---|---|---|
| JSY | Janani Suraksha Yojana | Cash incentive for institutional delivery (especially BPL) |
| JSSK | Janani Shishu Suraksha Karyakram | Free drugs, diagnostics, blood, diet, transport for pregnant women & sick neonates |
| PMSMA | Pradhan Mantri Surakshit Matritva Abhiyan | Free, assured, comprehensive ANC on 9th of every month at government health facilities |
| WIFS | Weekly Iron Folic Acid Supplementation | IFA supplementation for adolescent girls + pregnant women |
| PPTCT | Prevention of Parent-to-Child Transmission | HIV testing + ARV prophylaxis in pregnancy |
| Item | Number to Remember |
|---|---|
| Minimum ANC visits | 4 |
| 1st visit | Within 12 weeks |
| 2nd visit | 14-26 weeks |
| 3rd visit | 28-34 weeks |
| 4th visit | 36 weeks to term |
| High-risk: short stature | ≤ 140 cm |
| High-risk: elderly primi | ≥ 30 years |
| Anaemia in pregnancy (WHO) | Hb < 11 g/dL |
| Severe anaemia | Hb < 7 g/dL |
| IFA postpartum | 180 days |
| Normal weight gain | 10-12 kg total |
| TT-2 interval | 4 weeks after TT-1 |
| NTD prevention: folic acid timing | Before conception + first 12 weeks |
| Mnemonic | Covers |
|---|---|
| "12-26-34-TERM" | ANC visit schedule |
| "HEAL the BITE" | Components of ANC |
| "HURB STV" | Lab investigations |
| "IFA = Important For Anemia" | Iron-folic acid role |
| "TT at 16 and 20" | TT immunization schedule |
| "ESMAP + 3 Olds PAST" | High-risk pregnancy features |
| "NHS + S" | Grading of anaemia |
| "DRIB SAFE" | Health education advice |
| "SHE BLEED" | Danger signs in pregnancy |
| "JSY JSSK PMSMA" | Government schemes |
| "FLiPPE" | Abdominal palpation steps |
| "4 visits, 12-26-34-Term, 180, 140, 11" | Key numbers |
Pro exam tip: In PSM exams, drawing the 4-visit ANC schedule as a timeline diagram and the high-risk features as a box consistently earns extra marks. Mentioning PMSMA (9th of every month), JSY, and JSSK shows awareness of current national programmes - examiners love this. Danger signs with the mnemonic "SHE BLEED" is a guaranteed scoring point if asked as a sub-question.
Describe epidemiology, prevention and control of Tuberculosis.
| Property | Detail |
|---|---|
| Staining | Acid-fast bacillus (AFB) - Ziehl-Neelsen stain (carbol fuchsin → red bacilli) |
| Gram stain | Gram-positive but difficult to stain |
| Shape | Slender, slightly curved rod |
| Growth | Slow-growing; takes 6-8 weeks on Lowenstein-Jensen (LJ) medium |
| Resistance | Resistant to drying; survives in dark, dusty environments for weeks |
| Sensitivity | Killed by sunlight, UV light, heat (60°C for 20 min), common disinfectants |
| Letter | Condition |
|---|---|
| D | Diabetes mellitus (3x increased risk; "lethal duet") |
| I | Immunosuppression (steroids, TNF-inhibitors) |
| A | Alcoholism + tobacco use |
| M | Malignancy (especially hematological) |
| O | Other lung diseases (silicosis - 30x risk) |
| N | Nutrition - malnutrition |
| D | Dialysis / renal failure |
| Route | Detail |
|---|---|
| Airborne (main) | Inhalation of droplet nuclei (Wells' droplet nuclei) produced by coughing, sneezing, speaking, singing |
| Droplet infection | Large droplets settle quickly; droplet nuclei (<5 µm) stay suspended for hours |
| Ingestion | M. bovis via infected cow's milk → intestinal TB (now rare with pasteurization) |
| Inoculation | Direct inoculation through skin (rare - "prosector's wart") |
| Congenital | Transplacental spread (very rare - congenital TB) |
KEY FACT: Droplet nuclei (1-5 µm diameter) can remain suspended in air for hours and reach alveoli. Large droplets (>5 µm) are filtered out in upper respiratory tract.
Exposure to M. tuberculosis
↓
PRIMARY INFECTION (Ghon Focus)
↓
90-95% 5-10%
↓ ↓
LATENT TB PRIMARY PROGRESSIVE TB
(Dormant bacilli) (especially in children,
Lifetime risk: immunocompromised)
5-10% reactivation
↓
REACTIVATION (POST-PRIMARY TB)
(Most adult TB = reactivation of latent focus)
| Index | Definition |
|---|---|
| Prevalence | Number of cases (old + new) per 100,000 population at a given time |
| Incidence | Number of new cases per 100,000 population per year |
| ARTI | Annual Risk of Tuberculosis Infection - probability of a person being infected during 1 year |
| Notification rate | Number of cases notified to programme per 100,000/year |
| Treatment success rate | % of cohort achieving cure + treatment completed |
| Case fatality rate | Deaths among registered cases |
| Default rate | Patients lost to follow-up |
ARTI is the most sensitive indicator of TB burden in a community. A 1% ARTI means 1 in 100 uninfected persons gets infected per year.
"Tuberculosis control means reduction in the prevalence and incidence of disease in the community."
| Test | Details |
|---|---|
| Sputum Smear Microscopy (ZN stain) | Method of choice; cheap, fast, specific. 2 samples (spot + early morning). Detects AFB. Positivity threshold: 10,000 bacilli/mL |
| Chest X-ray | Infiltrates, cavitations, upper lobe involvement, hilar adenopathy. Not diagnostic alone |
| CBNAAT (Xpert MTB/RIF) | Cartridge-based nucleic acid amplification test. WHO-endorsed. Detects M. tuberculosis AND rifampicin resistance simultaneously in ~2 hours. First-line test in India under NTEP |
| Culture (LJ medium) | Gold standard. Takes 6-8 weeks. For drug susceptibility testing (DST) |
| MGIT (liquid culture) | Results in ~42 days. Faster than LJ medium |
| Mantoux/Tuberculin test | Indicates infection (not disease). 0.1 mL PPD (2TU) intradermally; read at 48-72 hours. Positive: ≥10 mm induration (immunocompromised: ≥5 mm) |
| IGRA (Interferon Gamma Release Assay) | More specific than Mantoux; not affected by BCG vaccination |
| Line Probe Assay (LPA) | Detects MDR-TB quickly |
| Drug | Mechanism | Major Side Effect |
|---|---|---|
| R - Rifampicin (RMP) | RNA polymerase inhibitor; bactericidal; kills "persisters" | Orange urine/tears, hepatotoxicity, drug interactions (induces CYP450) |
| I - Isoniazid (INH/H) | Mycolic acid synthesis inhibitor; bactericidal | Peripheral neuropathy (prevented by Pyridoxine B6), hepatotoxicity |
| P - Pyrazinamide (PZA/Z) | Kills intracellular slow-multiplying bacilli; bactericidal | Hepatotoxicity, hyperuricaemia (gout) |
| E - Ethambutol (EMB) | Arabinogalactan synthesis inhibitor; bacteriostatic | Retrobulbar neuritis (visual disturbance, colour blindness) |
| Category | Patients | Regimen |
|---|---|---|
| New DS-TB | New/previously treated DS-TB (all forms) | 2HRZE / 4HR (6 months total) |
| MDR-TB | Resistance to at least H + R | Long regimen (18-24 months) with second-line drugs |
| XDR-TB | MDR-TB + resistance to fluoroquinolones + second-line injectables | Individualised regimen |
DOTS (Directly Observed Treatment, Short-course): Healthcare worker directly observes patient swallowing every dose. Prevents drug resistance from irregular treatment.
| Type | Definition |
|---|---|
| MDR-TB | Resistant to at least Isoniazid + Rifampicin |
| Pre-XDR-TB | MDR/RR-TB + resistance to any fluoroquinolone |
| XDR-TB | MDR/RR-TB + resistance to fluoroquinolones + second-line injectables |
| RR-TB | Rifampicin-resistant TB (detected by Xpert) |
| Protection Against | Efficacy |
|---|---|
| Pulmonary TB (adult) | Variable: 0-80% (inconsistent across trials) |
| Miliary TB (in children) | 75-86% |
| Tuberculous meningitis | 75-86% |
| Leprosy | ~50% |
BCG is most effective against severe disseminated forms of TB in children (miliary + meningeal). It does NOT reliably prevent pulmonary TB reactivation in adults.
| Measure | Detail |
|---|---|
| N - Nutrition | Improve diet, combat malnutrition - boosts immunity |
| O - Overcrowding | Reduce overcrowding in homes, prisons, hostels |
| V - Ventilation | Adequate cross-ventilation; ceiling fans to disperse droplet nuclei |
| E - Education | Public awareness - recognize symptoms, seek early treatment, complete treatment |
| S - Sunlight | Encourage sunlight exposure; UV kills bacilli |
| + - Stop tobacco/alcohol | Both impair respiratory immunity |
| Target by 2030 | Goal |
|---|---|
| Reduce TB deaths by 90% (vs 2015) | |
| Reduce TB incidence by 80% (vs 2015) | |
| Zero TB-affected families with catastrophic costs |
| Component | Detail |
|---|---|
| P - Political commitment | Government funding, integration with health system |
| P - Patient-centered care | Free drugs, DOTS, nutritional support (Nikshay Poshan) |
| I - Intensified case finding | Active case finding in vulnerable groups |
| D - DOTS | Directly Observed Treatment for all patients |
| N - Nikshay | Mandatory notification + tracking portal |
| Fact | Number |
|---|---|
| Global infected (latent TB) | 1/3 of world population |
| Risk of active disease from infection | 5-10% |
| Persons infected by 1 smear-positive case/year | 10-15 |
| Global new TB cases (2019) | 10 million |
| India's share of global TB burden | 17% |
| High-burden countries (87% of global TB) | 30 |
| Incubation period to tuberculin positivity | 3-6 weeks |
| BCG efficacy (miliary/meningeal TB) | 75-86% |
| ARTI threshold for high-endemic area | >1% |
| TB mortality in HIV-negative (2019) | 1.2 million |
| India's TB elimination target | 2025 |
| Global SDG target | 2030 |
| Mnemonic | Topic |
|---|---|
| "AHE" | Epidemiological triad |
| "DIAMOND" | Risk factors / co-morbidities |
| "AD-I-C" | Routes of transmission |
| "PAINT" | TB indices |
| "RIPE" | First-line anti-TB drugs |
| "2HRZE / 4HR" | Standard treatment regimen |
| "SXCM" | Diagnostic tools |
| "NOVES" | Social/environmental control measures |
| "PPID + N" | NTEP components |
| "Zero = 90-80-0" | End TB targets |
| "3-10-17-30-10" | Key numbers |
| "CATS + B" | TB control strategy overview |
Pro exam tip: Drawing the "natural history of TB" flow diagram (exposure → latent → active disease) earns bonus marks. The ARTI definition is a frequent short-answer/MCQ question. Always mention that India contributes 17% of global TB burden and the target of TB-free India by 2025 - it demonstrates awareness of current national goals. The drug table with RIPE side effects is extremely high yield.
Epidemiology and its uses
"I keep six honest serving men; they taught me all I know. Their names are what, why, when, how, where and who." - Rudyard Kipling
| Word | Origin | Meaning |
|---|---|---|
| Epi | Greek | Among |
| Demos | Greek | People |
| Logos | Greek | Study |
| Author | Year | Definition |
|---|---|---|
| Parkin | 1873 | "That branch of medical science which treats epidemics" |
| Frost | 1927 | "The science of the mass phenomena of infectious diseases" |
| Greenwood | 1934 | "The study of disease, any disease, as a mass phenomenon" |
| MacMahon | 1960 | "The study of the distribution and determinants of disease frequency in man" |
"Epidemiology is the study of the distribution and determinants of health-related states or events in specified populations, and the application of this study to control of health problems."
"Epidemiology is the study of the distribution and determinants of disease frequency in man."
Key exam point: The IEA definition by Last is the most widely used and accepted definition in PSM exams.
| Component | Meaning | Type of Epidemiology |
|---|---|---|
| 1. Disease Frequency | Measurement of disease - prevalence, incidence, rates and ratios | Quantitative science - biostatistics |
| 2. Distribution | Patterns by TIME, PLACE, PERSON | Descriptive Epidemiology |
| 3. Determinants | Identifying causes/risk factors - testing aetiological hypotheses | Analytical Epidemiology |
| + Application | Using data for prevention, control, planning, evaluation | Applied Epidemiology |
| Letter | Aim |
|---|---|
| D | Describe the distribution and magnitude of health and disease problems in human populations |
| A | Identify aetiological factors (risk factors) in the pathogenesis of disease |
| P | Provide data essential to the planning, implementation and evaluation of services for prevention, control and treatment of disease |
| Feature | Epidemiology | Clinical Medicine |
|---|---|---|
| Unit of study | Defined population / population at risk | Individual case |
| Concern | Disease patterns in the entire population | Disease in the individual patient |
| Approach | Investigator goes into the community | Patient comes to the doctor |
| Method | Conceptual - tables, graphs, rates | Perceptual - clinical/lab examination |
| Objective | Identify source of infection, aetiology, control measures | Diagnosis, prognosis, treatment |
| Output | Rates, ratios, risk measures | Diagnosis + treatment plan |
| Focus | Both sick AND healthy | Only sick |
| Result | Public health policy | Individual care |
Classic quote: "Clinicians are interested in cases with the disease; the statistician with the population from which cases are derived; the epidemiologist is interested in the relationship between cases and the population in the form of a rate."
| Type | Description | Study Designs | Key Question |
|---|---|---|---|
| 1. Descriptive | Describes distribution by time, place, person | Cross-sectional surveys, ecological studies, case reports | "What? Who? Where? When?" - generates hypothesis |
| 2. Analytical | Tests aetiological hypotheses; identifies causation | Case-control, Cohort studies | "Why? How?" - tests hypothesis |
| 3. Experimental | Intervention to test hypotheses under controlled conditions | RCT, Field trials, Community trials | "Does this intervention work?" - proves/disproves hypothesis |
| Pattern | Example |
|---|---|
| Secular trend | Long-term change over decades (e.g., declining TB over 100 years) |
| Cyclical variation | Regular periodic fluctuations (e.g., influenza every winter) |
| Seasonal variation | Changes with season (e.g., cholera in monsoon) |
| Epidemic curve | Sudden rise in a common-source outbreak |
| Point epidemic | All cases from single source at one time (e.g., food poisoning) |
| Variable | Examples |
|---|---|
| Age | TB in 15-54 yrs; leukemia in children |
| Sex | Lung cancer more in males; thyroid disease more in females |
| Occupation | Silicosis in miners; byssinosis in cotton workers |
| Race/Ethnicity | Sickle cell in Africans; Tay-Sachs in Ashkenazi Jews |
| Religion | Cirrhosis less in Muslims (no alcohol) |
| Socioeconomic | TB more in poor; cardiovascular disease more in rich (in India) |
| Marital status | Some cancers differ |
| Family clustering | Genetic/infectious diseases |
| Design | Direction | Measures | Example |
|---|---|---|---|
| Case-Control | Retrospective (backward) | Odds Ratio (OR) | Smoking and lung cancer (Doll & Hill) |
| Cohort | Prospective (forward) | Relative Risk (RR), Incidence | Framingham Heart Study |
| Cross-sectional | At one point in time | Prevalence | National Family Health Survey (NFHS) |
| Type | Population | Example |
|---|---|---|
| Randomized Controlled Trial (RCT) | Patients | Drug trial |
| Field Trial | Healthy high-risk individuals | Salk polio vaccine trial |
| Community Trial | Entire communities | Water fluoridation trial |
| # | Use | Explanation |
|---|---|---|
| 1 | H - Historical study of rise and fall of disease | |
| 2 | C - Community diagnosis | |
| 3 | P - Planning and evaluation | |
| 4 | R - Risk evaluation for individuals | |
| 5 | S - Syndrome identification | |
| 6 | N - Natural history of disease | |
| 7 | I - Identifying new syndromes/causes |
| Letter | Use | Key Example |
|---|---|---|
| Hi | History - rise and fall of disease | CHD epidemic; smallpox eradication; AIDS emergence |
| C | Community diagnosis | NFHS, burden of disease studies |
| P | Planning and evaluation | Planning hospital beds, immunization campaigns |
| R | Risk evaluation | RR of lung cancer in smokers; age risk for Down syndrome |
| I | Identification of syndromes | Differentiating gastric vs. duodenal ulcer |
| N | Natural history of disease | 1/3 of IHD deaths are sudden death |
| S | Search for causes/determinants | Snow + cholera; Doll + cigarettes + lung cancer |
Parallel: As a physician diagnoses an individual patient, the epidemiologist "diagnoses" the health of a community.
The application of epidemiological principles to health care is called the "new epidemiology"
Classic example: Epidemiology revealed that one-third to two-thirds of all deaths due to ischaemic heart disease are sudden (occurring in less than one hour) - this could never have been discovered from hospital studies alone.
| Epidemiologist | Discovery |
|---|---|
| John Snow (1854) | Linked cholera to contaminated water (Broad Street pump) |
| Doll and Hill (1950) | Linked cigarette smoking to lung cancer |
| Bradford Hill | Established criteria for causation (Hill's criteria) |
| Burkitt | Linked EBV to Burkitt's lymphoma through observations in Africa |
| Goldberger | Linked pellagra to dietary niacin deficiency (not infection) |
| Epidemiology Type | Focus |
|---|---|
| C - Chronic disease epidemiology | CVD, diabetes, cancer |
| O - Occupational epidemiology | Silicosis, byssinosis, cancer |
| C - Clinical epidemiology | Evidence-based medicine |
| N - Neuro-epidemiology | Stroke, epilepsy, Alzheimer's |
| O - Oncological / Cancer epidemiology | Risk factors, incidence |
| P - Psychosocial epidemiology | Mental health, stress |
| S - Serological epidemiology | Antibody surveys |
| G - Genetic epidemiology | Gene-environment interactions |
AGENT
/\
/ \
/ \
/ DISEASE\
/----------\
HOST -------- ENVIRONMENT
| Measure | Definition |
|---|---|
| P - Prevalence rate | All existing cases (new + old) at a point in time ÷ population × 1000 |
| R - (Incidence) Rate | New cases in a period ÷ population at risk × 1000 |
| I - Incidence | Number of new cases in a defined period |
| M - Mortality rate | Deaths ÷ population × 1000 |
| O - Odds Ratio | Used in case-control studies; approximates RR |
| Topic | Key Point |
|---|---|
| Best definition | IEA/Last: "Distribution, determinants... application to control" |
| 3 components of definition | Disease frequency, Distribution (TPP), Determinants |
| 3 aims (IEA) | Describe, Aetiology, Planning (DAP) |
| Unit of study | Population (not individual) |
| 7 uses (Morris) | HiC-PRINS (History, Community Dx, Planning, Risk, Identify syndromes, Natural history, Search causes) |
| Types | Descriptive, Analytical, Experimental |
| Time distribution | Secular, cyclical, seasonal, epidemic |
| Place distribution | Spot map, geographic variation |
| Person distribution | Age, sex, race, occupation, SES |
| John Snow's contribution | Cholera + Broad Street pump = first epidemiological study |
| Classic comparison | Population vs. Patient |
| Mnemonic | Topic |
|---|---|
| "EPI-DEMOS-LOGOS" | Etymology |
| "3D's - DDD" | Three components of definition |
| "DAP" | Three aims of epidemiology |
| "Pop vs. Patient" | Epi vs. Clinical medicine |
| "Ask and Compare" | Epidemiological approach |
| "DAE" | Three types of epidemiology |
| "TPP" | Descriptive epidemiology variables |
| "HiC-PRINS" | 7 uses of epidemiology (Morris) |
| "AHE on a Web" | Epidemiological triad |
| "PRIMO" | Measurements in epidemiology |
| "COCNOPS-G" | Scope of modern epidemiology |
| "Snow Smokes, Doll Dreads" | Classic epidemiological discoveries |
Pro exam tip: The 7 uses of Morris is the most important part - aim to write a paragraph on each use with at least one example per use. The John Snow cholera story (linking cholera to the Broad Street pump in 1854) is the single most famous example in epidemiology and earns marks in almost every use you mention it in. Drawing the epidemiological triad triangle diagram always impresses examiners.
Which kind of questions will ask from nutrition chapter
| # | Question | Marks |
|---|---|---|
| 1 | Define Protein Energy Malnutrition (PEM). Describe the clinical features, grading, prevention and control of PEM in children. | 10-20 |
| 2 | Describe the classification, clinical features, prevention and control of Vitamin A deficiency (VAD) / Xerophthalmia. | 10-15 |
| 3 | What is balanced diet? Describe the nutritional requirements of a pregnant woman / adult male / child. | 10-15 |
| 4 | Describe the epidemiology, clinical features, prevention and control of Iron Deficiency Anaemia (IDA). | 10-15 |
| 5 | Nutritional assessment methods - classify and describe in detail. | 10 |
| 6 | Define and classify malnutrition. Describe the national nutritional programmes in India. | 10-15 |
| 7 | Iodine Deficiency Disorders (IDD) - epidemiology, clinical features, prevention and control. | 10 |
| Question |
|---|
| Kwashiorkor vs. Marasmus - differentiate |
| Vitamin D deficiency / Rickets / Osteomalacia |
| Pellagra (Niacin/Vit B3 deficiency) - "3D's" |
| Scurvy (Vit C deficiency) |
| Beriberi (Vit B1/Thiamine deficiency) |
| Fluorosis - dental and skeletal |
| Zinc deficiency |
| Folate deficiency and Neural Tube Defects |
| Question |
|---|
| Gomez classification (weight for age) |
| Wellcome classification (Kwashiorkor/Marasmus) |
| IAP classification of malnutrition |
| Waterlow classification (wasting + stunting) |
| Mid-Upper Arm Circumference (MUAC) - interpretation |
| Weight for height / Height for age indices |
| Z-scores and standard deviations in nutrition |
| Question |
|---|
| ICDS (Integrated Child Development Services) scheme |
| National Nutrition Mission (POSHAN Abhiyan) |
| Mid-Day Meal (MDM) programme |
| Vitamin A prophylaxis programme |
| National Iodine Deficiency Disorders Control Programme (NIDDCP) |
| Iron and Folic Acid supplementation (WIFS, Anaemia Mukt Bharat) |
| National Nutritional Anaemia Control Programme |
| Topic | Key Number |
|---|---|
| Kwashiorkor: weight deficit | 60-80% of expected weight |
| Marasmus: weight deficit | <60% of expected weight |
| Bitot's spots | Vitamin A deficiency (XN/X1B) |
| Night blindness (Nyctalopia) | First sign of VAD |
| WHO Vitamin A dose (6-12 months) | 1,00,000 IU |
| WHO Vitamin A dose (>1 year) | 2,00,000 IU (every 6 months) |
| Anaemia in pregnancy (WHO) | Hb < 11 g/dL |
| Anaemia in children <5 yrs | Hb < 11 g/dL |
| Anaemia in adults (male) | Hb < 13 g/dL |
| Protein requirement (adult) | 0.83 g/kg/day (WHO) |
| Calories (adult male sedentary) | 2320 kcal/day |
| Calories (adult female sedentary) | 1900 kcal/day |
| Extra calories in pregnancy | +350 kcal/day |
| Extra calories in lactation | +550 kcal/day |
| BMI normal range | 18.5-24.9 kg/m² |
| Overweight BMI | 25-29.9 |
| Obese BMI | ≥30 |
| Iodine in salt (India) | 15 ppm at consumer level |
| MUAC for SAM (<5 yrs) | <11.5 cm |
| MUAC for MAM (<5 yrs) | 11.5-12.5 cm |
| MUAC normal | ≥12.5 cm |
HIGH FREQUENCY (guaranteed to appear):
✅ PEM (Kwashiorkor/Marasmus)
✅ Vitamin A deficiency/Xerophthalmia
✅ Iron Deficiency Anaemia
✅ Nutritional assessment methods/classification
✅ National nutrition programmes (ICDS, POSHAN)
✅ Balanced diet / Nutritional requirements
MEDIUM FREQUENCY:
🔶 Iodine deficiency disorders
🔶 Vitamin D deficiency / Rickets
🔶 BMI and obesity
🔶 Fluorosis
🔶 MUAC and growth monitoring
LOWER FREQUENCY (but viva/MCQ important):
🔷 Pellagra, Scurvy, Beriberi
🔷 Zinc, Folate deficiencies
🔷 Breastfeeding and complementary feeding
🔷 Food adulteration / PFA Act
🔷 Essential fatty acids
| Mnemonic | Topic |
|---|---|
| "ABCDE" | Nutritional assessment methods (Anthropometry, Biochemical, Clinical, Dietary, Ecological) |
| "3 D's" | Pellagra - Dermatitis, Diarrhoea, Dementia (4th D = Death) |
| "WICKED" | Kwashiorkor features (W-oedema edema, I-Irritable, C-Changed hair, K-Kwashiorkor look, E-Enlarged liver, D-Depigmentation) |
| "XN, X1A, X1B, X2, X3A, X3B" | WHO Xerophthalmia classification |
| "Gomez 1-2-3" | Grade 1: 75-90%, Grade 2: 60-74%, Grade 3: <60% |
| "ICDS: Jyoti Se Poshan" | ICDS services (Immunization, Supplementary nutrition, Health check-up, Referral, Pre-school education, Nutrition + Health education) |
PEM
PEM is the most common nutritional disorder in developing countries and an underlying cause in 30% of deaths among children under 5 years of age.
| Indicator | Prevalence |
|---|---|
| Low birth weight (<2500 g) | 18.5% |
| Underweight (weight-for-age <-2SD) | 35.7% |
| Stunting (height-for-age <-2SD) | 38.4% |
| Wasting (weight-for-height <-2SD) | 21% |
| Kwashiorkor/Marasmus | <1% |
MALNUTRITION
↓ ↑
Reduced immunity → Infections (diarrhoea, ARI,
measles, worms)
↑ ↓
Reduced absorption, increased requirements,
decreased appetite
| Factor | Detail |
|---|---|
| P - Poverty | Inability to buy adequate food |
| A - Adverse feeding practices | Over-diluted cow's milk, discarding cooking water from cereals |
| L - Large family size | More mouths, less food per child |
| M - Maternal malnutrition | Malnourished mother → LBW baby → cycle continues |
| F - Failure of breastfeeding | Premature termination of breastfeeding |
| I - Infections | Diarrhoea, ARI, measles, intestinal worms |
| B - Bad environment | Poor sanitation, overcrowding |
| C - Cultural practices | Delayed supplementary feeding, food taboos |
"Malnutrition is self-perpetuating": A malnourished mother → LBW infant → malnourished child → malnourished adult woman → cycle continues across generations.
| Grade | Weight for Age (% of expected) | Classification |
|---|---|---|
| Normal | ≥ 90% | Well-nourished |
| Grade I (Mild) | 75 - 90% | Mild PEM |
| Grade II (Moderate) | 60 - 74% | Moderate PEM |
| Grade III (Severe) | < 60% | Severe PEM (Marasmus) |
Gomez limitation: Does NOT differentiate between oedematous (Kwashiorkor) and non-oedematous malnutrition; cannot distinguish wasting from stunting.
| Weight for Age | No Oedema | With Oedema |
|---|---|---|
| 60 - 80% of expected | Undernutrition | Kwashiorkor |
| < 60% of expected | Marasmus | Marasmic Kwashiorkor |
This classification is critical - oedema is the key differentiator between Kwashiorkor and Marasmus.
| Wasting (Wt/Ht) | |||
|---|---|---|---|
| Normal ≥ 90% | Wasted < 90% | ||
| Stunting | Normal ≥ 95% | Normal | Wasted only (Acute) |
| (Ht/Age) | Stunted < 95% | Stunted only (Chronic) | Wasted + Stunted (Chronic+Acute) |
| Grade | Weight for Age (% of median) |
|---|---|
| Normal | >80% |
| Grade I | 71-80% |
| Grade II | 61-70% |
| Grade III | 51-60% |
| Grade IV | ≤50% |
Note: IAP revised classification now uses WHO Growth Standards and Z-scores (see below).
| Z-Score | Classification |
|---|---|
| ≥ -1 SD | Normal |
| -1 to -2 SD | At risk |
| -2 to -3 SD | Moderate Malnutrition (MAM) |
| < -3 SD | Severe Malnutrition (SAM) |
| Index | Condition it measures |
|---|---|
| Weight-for-Age (WFA) | Underweight (composite) |
| Height-for-Age (HFA) | Stunting (chronic malnutrition) |
| Weight-for-Height (WFH) | Wasting (acute malnutrition) |
| MUAC | Classification | Colour Code |
|---|---|---|
| < 11.5 cm | SAM (Severe Acute Malnutrition) | 🔴 Red |
| 11.5 - 12.5 cm | MAM (Moderate Acute Malnutrition) | 🟡 Yellow |
| ≥ 12.5 cm | Normal | 🟢 Green |
MUAC can be used from age 1 to 5 years; NOT valid before 1 year.
| Letter | Feature |
|---|---|
| F | Fatty liver (hepatomegaly) |
| A | Anaemia + apathy/irritability |
| C | Changed hair (flag sign - alternating light/dark bands; reddish-brown discolouration) |
| E | Edema (pitting oedema - hallmark feature) |
| D | Depigmentation of skin and hair |
| S | Skin changes (flaky paint dermatosis, hypo/hyperpigmentation) |
| H | Hypoalbuminaemia (serum albumin < 3 g/dL) |
| O | Oedema (pitting, starts at feet) |
| P | Poor appetite, Psychomotor changes (miserable look) |
| Feature | Marasmus |
|---|---|
| Appearance | "Old man face" (wizened, senile-looking), "skin and bones" |
| Wasting | Severe muscle + subcutaneous fat wasting |
| Weight | < 60% of expected |
| Oedema | ABSENT |
| Hair | Usually normal |
| Skin | Loose, wrinkled (baggy pants appearance) |
| Albumin | Near normal |
| Appetite | Usually preserved/increased |
| Liver | Normal |
| Feature | Kwashiorkor | Marasmus |
|---|---|---|
| Cause | Low protein/energy ratio (mainly protein deficiency) | Deficiency of both protein AND energy (total starvation) |
| Age | 1-3 years (weaning age) | < 1 year (infancy) |
| Onset | Often after weaning | Gradual, early infancy |
| Weight deficit | 60-80% of expected | < 60% of expected |
| Oedema | Present (hallmark) | Absent |
| Muscle wasting | Moderate | Severe |
| Subcutaneous fat | Preserved (masked by oedema) | Markedly reduced |
| Skin | Flaky paint dermatosis, hyper/hypopigmentation | Wrinkled, loose ("baggy pants") |
| Hair | Depigmented, thin, sparse, flag sign | Less affected |
| Face | Moon face (oedema) | Old man face / monkey facies |
| Liver | Enlarged (fatty) | Normal |
| Albumin | Very low (<3 g/dL) | Near normal |
| Appetite | Poor, irritable | Relatively good |
| Mental status | Apathetic, miserable | Alert, irritable |
| Mortality | Higher (if untreated) | Lower (but severe) |
| Method | Detail |
|---|---|
| A - Anthropometry | Weight, height, MUAC, skinfold thickness, head circumference, growth charts |
| B - Biochemical | Serum albumin (<3 g/dL = hypoalbuminaemia), Hb, serum retinol, urine creatinine-height index |
| C - Clinical | Signs and symptoms (oedema, skin, hair, liver, moon face, wasting) |
| D - Dietary | 24-hour dietary recall, food frequency questionnaire |
| E - Ecological | Socioeconomic assessment, cultural factors, food availability, maternal education |
"The first indicator of PEM is underweight for age" - best monitored using growth charts (Road to Health chart)
| Phase | Step | Intervention |
|---|---|---|
| Stabilization Phase (Days 1-2) | 1 | Treat/prevent HYPOGLYCAEMIA - give glucose/feed every 30 min |
| 2 | Treat/prevent HYPOTHERMIA - keep warm, KMC | |
| 3 | Treat/prevent DEHYDRATION - ORS (modified, low-Na ReSoMal) | |
| 4 | Correct ELECTROLYTE imbalance (K+, Mg++, Na+) | |
| 5 | Treat/prevent INFECTION - broad-spectrum antibiotics | |
| 6 | Correct MICRONUTRIENT deficiencies (Vitamin A, Zinc, Folate, Fe - but iron LATER) | |
| Rehabilitation Phase (Weeks 2-6) | 7 | Start CAUTIOUS FEEDING - Starter Formula (F-75 = 75 kcal/100mL) |
| 8 | Achieve CATCH-UP GROWTH - high energy F-100 (100 kcal/100mL) | |
| 9 | Provide SENSORY STIMULATION - play therapy, emotional support | |
| Follow-up | 10 | FOLLOW-UP after discharge - home visits, community monitoring |
| Phase | Duration | Diet |
|---|---|---|
| Stabilization | Days 1-2 | F-75 (starter diet, 75 kcal/100 mL) |
| Transition | Days 3-7 | F-75 → F-100 (gradual) |
| Rehabilitation | Weeks 2-6 | F-100 (100 kcal/100 mL) |
| Follow-up | Weeks 7-26 | RUTF (Ready-to-Use Therapeutic Food) |
RUTF = Ready to Use Therapeutic Food (e.g., Plumpy'Nut - peanut paste + powdered milk + sugar + oil + vitamins). Used for outpatient management of uncomplicated SAM.
NRC = Nutritional Rehabilitation Centre - facility-based management for SAM with medical complications
| Measure | Detail |
|---|---|
| Breastfeeding | Exclusive breastfeeding for 6 months; continue up to 2 years |
| Complementary feeding | Start at 6 months; nutrient-dense, locally available foods |
| Nutrition education | Promote correct child feeding practices |
| Maternal nutrition | Improve diet of pregnant + lactating women; IFA supplementation |
| Low-cost weaning foods | Use locally available protein-rich foods (dal, eggs, groundnut) |
| Family planning | Spacing of births; smaller family size |
| Measure | Detail |
|---|---|
| Protein + energy rich diet | Milk, eggs, pulses, fish |
| Immunization | Protect against measles, whooping cough, diarrhoea - all worsen malnutrition |
| Vitamin A supplementation | Prevents VAD + infections that worsen PEM |
| Deworming | 6-monthly albendazole for children >12 months |
| Programme | Target | Key Feature |
|---|---|---|
| ICDS (Integrated Child Development Services) | Children 0-6 yrs + pregnant/lactating mothers | Supplementary nutrition, immunization, health check-up, pre-school education |
| POSHAN Abhiyan (National Nutrition Mission) | Children, adolescents, pregnant/lactating women | Reduce stunting by 2%, wasting by 2%, underweight by 2% per year |
| Anaemia Mukt Bharat | All age groups | IFA supplementation, WIFS, deworming |
| NRCs (Nutritional Rehab Centres) | SAM children <5 yrs | Facility-based care |
| PMMVY | Pregnant/lactating women | ₹5000 maternity benefit |
| Mid-Day Meal (MDM) | School children | Improve nutrition + school attendance |
| WIFS (Weekly Iron Folic Acid Supplementation) | Adolescent girls + pregnant women | IFA tablets weekly |
| Fact | Number |
|---|---|
| Kwashiorkor - weight deficit | 60-80% of expected |
| Marasmus - weight deficit | <60% of expected |
| Kwashiorkor - typical age | 1-3 years |
| Marasmus - typical age | < 1 year |
| MUAC - SAM | < 11.5 cm |
| MUAC - MAM | 11.5-12.5 cm |
| MUAC - Normal | ≥ 12.5 cm (old standard) |
| MUAC - valid age range | 1-5 years |
| India - stunting prevalence | 38.4% (NFHS-4) |
| India - wasting prevalence | 21% (NFHS-4) |
| India - underweight | 35.7% (NFHS-4) |
| Gomez Grade I | 75-90% |
| Gomez Grade II | 60-74% |
| Gomez Grade III | <60% |
| F-75 (Starter formula) | 75 kcal/100 mL |
| F-100 (Catch-up formula) | 100 kcal/100 mL |
| PEM as cause of under-5 deaths | 30% |
| Mnemonic | Topic |
|---|---|
| "PALM-FIBC" | Causes/contributing factors of PEM |
| "Malnutrition-Infection Vicious Cycle" | Pathogenesis |
| "Gomez 1-2-3 = 90, 75, 60" | Gomez classification |
| "WELLcome = WEight + oeLLedema" | Wellcome classification |
| "WATERlow = WAsting + sTuntERing" | Waterlow classification |
| "Red-Yellow-Green" | MUAC colour coding (SAM-MAM-Normal) |
| "FACED SHOP" | Kwashiorkor clinical features |
| "3 W's" | Marasmus: Wasted, Wizened, Wrinkled |
| "ABCDE" | Nutritional assessment methods |
| "ICAN-PWM" | National nutrition programmes |
| "60-80 Kwashi, <60 Marasmus" | Key weight thresholds |
Pro exam tip: The Kwashiorkor vs. Marasmus comparison table written as a neat two-column table gets maximum marks in a short time. The Wellcome classification (the 2x2 box with oedema vs. weight) is a guaranteed examiner-favourite diagram. Always quote NFHS-4 figures for India's malnutrition burden - it shows you know current statistics.
Balanced diet
A balanced diet has become an accepted means to safeguard a population from nutritional deficiencies.
| Nutrient | % of Daily Energy Intake |
|---|---|
| Protein | 10-15% of daily energy intake (first priority) |
| Fats | 15-30% of daily energy intake |
| Carbohydrates | Remaining energy (rich in natural fibre) |
| Micronutrients | As per RDA (vitamins + minerals) |
"The word 'protein' by derivation means that which is of first importance."
| Letter | Amino Acid |
|---|---|
| P | Phenylalanine |
| V | Valine |
| T | Threonine |
| T | Tryptophan |
| I | Isoleucine |
| M | Methionine |
| H | Histidine |
| L | Leucine |
| L | Lysine |
Body cannot synthesize essential amino acids → must be obtained from diet. Non-essential amino acids (arginine, glutamic acid, glycine, serine, proline) can be synthesized by the body.
| Function | Detail |
|---|---|
| B - Body building | Growth of new tissues |
| O - Osmotic pressure | Maintains plasma oncotic pressure (albumin) |
| R - Repair + maintenance | Replacing worn-out tissues |
| S - Synthesis | Antibodies, enzymes, hormones, haemoglobin, coagulation factors |
| I - Immunity | Cell-mediated immune response, bactericidal activity of macrophages |
| Group | Protein (g/day) |
|---|---|
| Adult man (sedentary) | 54 g/day |
| Adult woman (sedentary) | 46 g/day |
| Pregnant woman | +23 g/day extra |
| Lactating (0-6 months) | +19 g/day extra |
| General (WHO) | 0.83 g/kg/day |
Limiting amino acid: The essential amino acid present in the lowest amount in a protein relative to body needs. In cereals = lysine is the limiting amino acid. In pulses = methionine.
| Type | Examples | Key Feature |
|---|---|---|
| Monosaccharides | Glucose, fructose, galactose | Simplest; directly absorbed |
| Disaccharides | Sucrose, lactose, maltose | Split by digestive enzymes |
| Polysaccharides | Starch, glycogen, cellulose | Complex carbohydrates |
| Dietary Fibre | Cellulose, hemicellulose, pectin | Not digested but very important |
| Function | Detail |
|---|---|
| S - Spare protein | When carbohydrates adequate, proteins used for synthesis (not energy) |
| A - Anti-ketogenic | Prevents ketosis; required for fat oxidation |
| F - Fuel for CNS | Glucose is the only fuel for brain/nerve tissue |
| E - Energy source | Primary energy source; 55-65% of total energy should come from CHO |
| Type | Example | Source | Health Effect |
|---|---|---|---|
| Saturated Fatty Acids (SFA) | Palmitic, stearic | Animal fat, coconut oil, ghee | ↑ LDL, ↑ CVD risk |
| Monounsaturated (MUFA) | Oleic acid (omega-9) | Olive oil, groundnut oil | Neutral/beneficial |
| Polyunsaturated (PUFA) | Linoleic (ω-6), α-linolenic (ω-3) | Sunflower, fish oils | ↓ LDL, ↓ CVD risk |
| Trans fats | Partially hydrogenated vegetable oil (vanaspati) | Margarine, processed foods | ↑ LDL, ↓ HDL - WORST |
| Function | Detail |
|---|---|
| C - Concentrated energy | 9 kcal/g (double of CHO/protein) |
| A - Absorption of fat-soluble vitamins | Vitamins A, D, E, K need fat for absorption |
| V - Vital organs protection | Cushions kidneys, heart |
| E - Essential fatty acids | Linoleic, alpha-linolenic |
| A - Adipose tissue (insulation) | Body temperature regulation |
| T - Taste and palatability | Improves food palatability |
| S - Satiety | Delays gastric emptying |
| Category | Vitamins | Key Feature |
|---|---|---|
| Fat-soluble | A, D, E, K | Stored in body; toxicity possible with excess |
| Water-soluble | B complex (B1, B2, B3, B6, B12), C, Folic acid, Biotin, Pantothenic acid | Not stored; regular intake needed |
| Vitamin | Function | Deficiency Disease | Source |
|---|---|---|---|
| A (Retinol) | Vision, epithelium, immunity | Xerophthalmia, Night blindness | Liver, egg, carrot, green leafy vegetables |
| D (Calciferol) | Ca/P absorption, bone mineralisation | Rickets (children), Osteomalacia (adults) | Sunlight (main), fish oil, egg |
| E (Tocopherol) | Antioxidant, membrane integrity | Haemolytic anaemia (newborn), infertility | Vegetable oils, nuts, wheat germ |
| K (Phylloquinone) | Blood coagulation (factors II,VII,IX,X) | Bleeding tendency | Green leafy vegetables, synthesized by gut bacteria |
| B1 (Thiamine) | CHO metabolism (pyruvate dehydrogenase) | Beriberi (wet/dry) | Whole grains, legumes |
| B2 (Riboflavin) | Oxidative phosphorylation | Angular stomatitis, corneal vascularisation | Milk, liver, eggs |
| B3 (Niacin) | NAD/NADP - energy metabolism | Pellagra (3Ds): Dermatitis, Diarrhoea, Dementia | Meat, fish, peanuts; from tryptophan |
| B6 (Pyridoxine) | Amino acid metabolism, Hb synthesis | Peripheral neuropathy, sideroblastic anaemia | Meat, fish, poultry, banana |
| B12 (Cobalamin) | DNA synthesis, nerve myelin | Megaloblastic anaemia, subacute combined degeneration | Animal foods only (meat, milk, egg) |
| C (Ascorbic acid) | Collagen synthesis, antioxidant, Fe absorption | Scurvy (bleeding gums, perifollicular haemorrhage) | Fresh fruits, citrus, amla (richest source) |
| Folic acid | DNA synthesis, neural tube formation | Megaloblastic anaemia, Neural Tube Defects | Green leafy vegetables, legumes, liver |
| Type | Minerals | Amount needed |
|---|---|---|
| Macrominerals | Ca, P, Mg, Na, K, Cl | >100 mg/day |
| Microminerals (Trace elements) | Fe, Zn, I, Cu, Mn, Se, Cr, F | <100 mg/day |
| Mineral | Function | Deficiency | RDA (Indian adult) |
|---|---|---|---|
| Ca (Calcium) | Bone/teeth formation, muscle contraction, clotting | Rickets, Osteomalacia, tetany | 1000 mg/day |
| Fe (Iron) | Haemoglobin, myoglobin, enzymes | Iron deficiency anaemia | Men: 19 mg/day; Women: 29 mg/day |
| I (Iodine) | Thyroid hormone (T3, T4) synthesis | Goitre, cretinism, IDD | 150 µg/day |
| Zn (Zinc) | Enzyme function, growth, immunity, wound healing | Growth retardation, poor wound healing, diarrhoea | 17 mg/day (men) |
| Na (Sodium) | Fluid balance, nerve transmission | Hyponatraemia | Limit to <5 g salt/day (WHO) |
| F (Fluoride) | Tooth enamel hardening | Dental caries | Excess → Fluorosis |
| Group | Foods | Primary Nutrients |
|---|---|---|
| 1. Cereals and millets | Rice, wheat, maize, jowar, bajra, ragi | Energy (CHO), some protein, B vitamins |
| 2. Pulses and legumes | Dal, peas, beans, groundnut, soybean | Protein, energy, iron, B vitamins |
| 3. Milk and milk products | Milk, curd, cheese, paneer | Protein, calcium, Vit B12, fat |
| 4. Meat, poultry, fish, eggs | Chicken, fish, eggs, mutton | Complete protein, iron, Vit B12, Zn |
| 5. Vegetables | Green leafy, roots, other vegetables | Vitamins (A, C, K, folate), minerals, fibre |
| 6. Fruits | Citrus, mango, banana, guava, amla | Vitamin C, fibre, antioxidants |
| 7. Fats and oils | Ghee, butter, vegetable oils | Energy, fat-soluble vitamins, EFA |
| 8. Sugar and jaggery | Sugar, jaggery, honey | Quick energy (empty calories) |
| 9. Condiments and spices | Garlic, ginger, turmeric, pepper | Palatability, carminative (no major nutrition) |
| 10. Water and beverages | Water, tea, coffee | Hydration |
"Go Foods" (energy) = Cereals; "Grow Foods" (protein/build) = Pulses, milk, meat; "Glow Foods" (protective) = Vegetables and fruits
| Group | Energy (kcal/day) - ICMR 2020 |
|---|---|
| Adult man (sedentary) | 2110 kcal/day |
| Adult man (moderate work) | 2710 kcal/day |
| Adult man (heavy work) | 3470 kcal/day |
| Adult woman (sedentary) | 1660 kcal/day |
| Adult woman (moderate work) | 2130 kcal/day |
| Pregnant woman (extra) | +350 kcal/day |
| Lactating (0-6 months) (extra) | +600 kcal/day |
| Lactating (7-12 months) (extra) | +520 kcal/day |
| Infant (0-6 months) | 550 kcal/day |
| Child (1-3 years) | 1010 kcal/day |
Note: ICMR 2010 gave 2320 kcal for sedentary man; revised DOWN to 2110 in ICMR 2020 - based on actual activity studies in India.
| Food | Quantity/day |
|---|---|
| Cereals (rice/wheat) | 460 g |
| Pulses (dal) | 40 g |
| Milk | 150 mL |
| Vegetables (green leafy) | 40 g |
| Vegetables (other) | 60 g |
| Roots/tubers | 50 g |
| Fruits | 30 g |
| Fats/oils | 40 g |
| Sugar/jaggery | 30 g |
| Nutrient | Extra Amount | Purpose |
|---|---|---|
| Energy | +350 kcal/day | Fetal growth + maternal stores |
| Protein | +23 g/day | Fetal tissue building |
| Calcium | +300 mg/day | Fetal bone development |
| Iron | +12.5 mg/day (as IFA supplement) | Prevent anaemia |
| Folic acid | 5 mg/day (periconceptional) | Neural tube defect prevention |
| Vitamin A | No extra (risk of teratogenicity in excess) | - |
| Nutrient | Extra Amount |
|---|---|
| Energy | +600 kcal/day (0-6 months); +520 (7-12 months) |
| Protein | +19 g/day |
| Calcium | +600 mg/day |
| Nutrient | Adult Man | Adult Woman | Pregnant |
|---|---|---|---|
| Energy | 2110 kcal | 1660 kcal | +350 kcal |
| Protein | 54 g/day | 46 g/day | +23 g/day |
| Calcium | 1000 mg | 1000 mg | 1200 mg |
| Iron | 19 mg | 29 mg | 35 mg |
| Iodine | 150 µg | 150 µg | 220 µg |
| Zinc | 17 mg | 10 mg | 12 mg |
| Vitamin C | 80 mg | 65 mg | 80 mg |
| Vitamin A | 1000 µg RE | 840 µg RE | 800 µg RE |
| Vitamin D | 600 IU | 600 IU | 600 IU |
| Folate | 300 µg | 220 µg | 500 µg |
| Dietary Fibre | 32 g | 25 g | 35 g |
| Recommendation | Detail |
|---|---|
| R - Reduce saturated fat | <10% of total energy; replace with PUFA |
| A - Avoid trans fats | <1% of total energy (eliminate vanaspati/partially hydrogenated oils) |
| L - Limit sugar | <10% of total energy (<5% for additional health benefits) |
| F - Fibre up | ≥25 g dietary fibre/day from whole grains, fruits, vegetables |
| S - Salt reduction | <5 g/day (India averages 15 g/day - very high!) |
| A - Adequate fruits and vegetables | ≥400 g/day (5 portions) |
| F - Fat 15-30% | Of total daily energy intake |
| E - Energy balance | Match energy intake to expenditure to maintain healthy weight |
▲ FATS/OILS/SWEETS
▲▲ (use sparingly)
▲▲▲ MILK / MEAT / FISH / EGGS
▲▲▲▲ (2-3 servings)
▲▲▲▲▲ VEGETABLES / FRUITS
▲▲▲▲▲▲ (3-5 / 2-4 servings)
▲▲▲▲▲▲▲ CEREALS / BREAD / RICE / PULSES
▲▲▲▲▲▲▲▲ (6-11 servings - BASE)
| Nutrient | Energy (kcal/g) |
|---|---|
| Carbohydrate | 4 kcal/g |
| Protein | 4 kcal/g |
| Fat | 9 kcal/g |
| Alcohol | 7 kcal/g |
| Term | Definition |
|---|---|
| RDA | Recommended Dietary Allowance - level of intake of a nutrient that meets the needs of almost all (97.5%) healthy people in a population |
| EAR | Estimated Average Requirement - meets the needs of 50% of individuals |
| BV (Biological Value) | % of absorbed protein retained in the body; egg = BV 100 (reference) |
| NPU (Net Protein Utilization) | BV × digestibility; measures overall protein quality |
| PER (Protein Efficiency Ratio) | Weight gain per g protein consumed (used in animal studies) |
| Limiting amino acid | The EAA in lowest proportion in a protein; determines protein quality |
| Empty calories | Foods providing energy but very little or no other nutrients (sugar, alcohol, junk food) |
| Nutrient density | Nutrient content per unit of energy of a food |
| Mnemonic | Topic |
|---|---|
| "CPFVMW" | 6 classes of nutrients |
| "PCM" | Principles of balanced diet (Protein 10-15%, CHO rest, Micronutrients) |
| "PVT TIM HaLL" | 9 Essential amino acids |
| "BORSI" | Functions of protein |
| "SAFE" | Functions of carbohydrates |
| "CAVEATS" | Functions of fats |
| "Fat ADEK, Water B+C" | Vitamin classification |
| "CAFI-ZINC" | Key minerals |
| "Go-Grow-Glow" | Food groups by function |
| "Men 2110, Women 1660, Preg +350, Lact +600" | Energy requirements (ICMR 2020) |
| "4-4-9" | Caloric values of nutrients |
| "RALF SAFE" | WHO dietary guidelines |
Pro exam tip: Drawing the Food Pyramid diagram and the 4-4-9 caloric table are guaranteed quick marks. The supplementary action of proteins (cereals + pulses = complete protein) is a very commonly asked short-note. Always differentiate fat-soluble (ADEK) vs. water-soluble vitamins (B+C) in a table format - examiners love it. The ICMR 2020 energy values have changed from 2010 - make sure you use the updated figures (2110 for sedentary man, NOT 2320).