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Pulmoclear syrup acebrophylline terbutaline sulphate menthol uses dosage

Here is a full breakdown of Pulmoclear Syrup (by Fourrts Pharmaceuticals, 100 ml):

Pulmoclear Syrup

Brand: Pulmoclear (Fourrts India) Category: Prescription (Rx) - Bronchodilator + Mucolytic combination Form: Oral Syrup, 100 ml

Composition

IngredientRole
AcebrophyllineBronchodilator + mucolytic (xanthine derivative - ambroxol + theophylline-7-acetate)
Terbutaline SulphateShort-acting beta-2 agonist bronchodilator
MentholCooling/soothing agent, mild decongestant

How Each Ingredient Works

1. Acebrophylline
  • A unique compound that combines the bronchodilator effects of theophylline with the mucolytic effects of ambroxol
  • Inhibits phosphodiesterase, raising cAMP levels to relax bronchial smooth muscle
  • Lowers mucus viscosity, increases mucociliary clearance
  • Has anti-inflammatory properties - suppresses TNF-alpha, leukotrienes, and phospholipase A
  • Overall: opens airways AND clears mucus
2. Terbutaline Sulphate
  • A selective beta-2 adrenergic agonist
  • Stimulates beta-2 receptors in the lungs, causing bronchial smooth muscle relaxation and airway widening
  • Acts faster than acebrophylline for acute bronchospasm relief
  • Also used as a tocolytic (uterine relaxant) in obstetric settings
3. Menthol
  • Produces a cooling sensation in the throat and airways
  • Acts as a mild topical decongestant and antitussive
  • Helps soothe irritated mucous membranes

Uses / Indications

  • Asthma - relieves wheezing, breathlessness, and cough
  • COPD (Chronic Obstructive Pulmonary Disease)
  • Chronic bronchitis - especially productive cough with thick mucus
  • Bronchospasm associated with respiratory tract infections
  • Cough with mucus (wet/productive cough)

Dosage (General Guidance)

Always follow your doctor's prescription.
  • Adults: Typically 10 ml (2 tsp) 2-3 times daily
  • Children (5+ years): 5 ml twice daily or as directed
  • Children (2-5 years): 2.5 ml three times daily
  • Below 2 years: 2.5 ml twice daily (only if prescribed)
Take with or without food. Shake well before use (as indicated on the bottle).

Common Side Effects

  • Nausea, vomiting
  • Palpitations / increased heart rate (from terbutaline)
  • Tremors, nervousness (from terbutaline)
  • Headache, dizziness
  • Bloating or upper abdominal discomfort

Precautions & Contraindications

  • Contraindicated in: Hypersensitivity to any component; active peptic ulcer; porphyria
  • Use with caution in: Heart disease, hypertension, hyperthyroidism, diabetes, seizure disorders, liver or kidney impairment
  • Do not drive or operate heavy machinery (can cause dizziness/drowsiness)
  • Pregnant/breastfeeding women: Consult a doctor - terbutaline carries FDA warnings for prolonged use in pregnancy
  • Avoid smoking and alcohol during treatment
  • Do not stop abruptly without consulting your doctor

Key Point

This is a Rx (prescription) medicine. The three-way combination is designed to address bronchospasm (terbutaline), airway inflammation and mucus clearance (acebrophylline), and airway soothing (menthol) simultaneously - making it particularly useful for productive cough in asthma and COPD. Always use under medical supervision.
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