*Chemotherapy* (10 MARKS) 1. Classification of beta lactam , MOA, Therapeutic uses,  A/E , contraindication of benzylpenicillin. 2. Classification of Cephalosporin, MOA, Therapeutic uses,  A/E , contraindication of Ceftriaxone. 3. Classification of Amino glycosides MOA, Therapeutic uses,  A/E , contraindication of  streptomycin 4. Classification of Anti tb drugs  MOA, Therapeutic uses,  A/E , contraindication of isoniazid/Rifamicin 5. Classification of Anti malarial drugs  MOA, Therapeutic uses,  A/E , contraindication of epimican. (5 MARKS) 1. Antibiotics Stawrdship Programme(ASP) 2. Superinfection and name drugs causing it. 3. Adv and disadv of antimicrobial combinations. 4. Beta lactamase inhibitors. 5. Imipicanum 6. Ceprofloxacin 7. Cutrimoxazole (sequential blockade of AMA) 8. Amoxicilin 9. Tetracycline and doxycycline 10. Chloramphtnifond 11. Azitromycin 12. Vancomycin 13. RNTCP 14. Guildlines for Drug resistant TB 15. Newer anti tb drugs 16. Classificatin of Anti leprotic drugs and dapsons 17. Lepra rxn and their management 18. Typhoid 19. Management of anaphylactic shock by penicilin. 20. Rationale behind combining amoxicilin with clavlanic acid 21. Adv of Doxycline over tetracycline. 22. Nitroflurointine 23. Drugs acting against MRSA 24. Amphotericin B 25. Ketoconazole 26. Acyclovir 27. Zidovudine 28. NNRTIs ** 29. Pyrimethamine 30. Metronidazole 31. Ivory mectin prazilqua 32. Diloxeanide** 33. HART 34. Treatment of HIV in Pregnancy 35. Cisplatin 36. Methotrexate 37. Vinca alkaloids 38. Purine antagonists 39. Drugs used to reduce toxicity due to anti cancer drugs. 40. Mescna ** *AETCOM* 1. Role of Doctor in healthcare system. 2. Principle of bioethics. 3. Implications of health care as right. 4. How to Break Bad News. *CNS* 1.classify antiepileptic drugs write moa adr use of sod.valporate/phenytoin 2.SSRI 3.mang.of status epilepticus 4.clssify opioid analgesic write moa adr use of morphine 5 . mangement of morphine poisoning (opioid antagonist) 6.Disulfiram reaction 7.cheese reaction and mangement 8.chlorpromazine 9.thiopentone sod. 10.ketamine(dissociation anaesthesia) 11.newer antiepileptic drugs 12.selegiline 13.drugs induced parkinson mangement 14.methonal poisoning 15.mang.of BZD poisoning 16.combination of levodopa and carbidopa why 17.t/t of schizophrenia 18.morphine is c/i in head injury 19.mania(li) as shot note 20.Atypical anti-psychotic *CVS* 1.clssify anti hypertension drugs moa adr use pharmacological action of enalapril (ace inhibitors)/telmisarton (arbs)/verapamil (ccb) 2. Mang.of hypertension crisis and emergency 3. Mang.of angina attack 4. Clonidine 5. Anti arrhythmic drugs -- amiodarone 6. Role of diuretic in hypertension 7. Drug used in Mi 8. Nifedipine 9. Nicorandil 10. Role of diuretic and vasodilator in CHF 11. Lignocaine in cardiac arrhythmia 12. Adenosine 13. Advantages of arbs over ace inhibitors 14. Combination of arbs and ace inhibitors over motherapy perferd why 15. Drugs in psvt 16. Anti hypertension drugs in pregnancy 17. Digoxin poisoning *Renal* 1.loop diuretic 2.acetazolamide 3.spironolactone 4.vasopresin analogue 5.aldosterone antagonist 6.furosemide and spironolactone combination why? 7.SIADH for 1mark *Blood* 1.low molecular weight heparin 2. Warferin 3. Anti platelets drugs (aspirin) 4. Why aspirin discontinued before one week of surgery patients 5. Fibrinolytic drugs 6. Streptokinase 7. Statins 8. Mang.of heparin and warfarin toxicity 9. Mangement of acute iron poisoning 10. C/i of thrombolytic therapy 11. Local hemostatic (Styptic)-1/2 Mark 12. Advantages of LMWH over the UFH General Pharma 1. Clinical drug trials 2. Factors affecting absorption 3. TDM 4. GPCR (Receptors) 5. Practical importance of drug response curve 6. Factors affecting drug action 7. FDC 8. OP poisoning (complete) 9. Glaucoma (complete) 10. COPD – 1 mark 11. β-blockers (LAQ) 12. α-blockers (SAQ) 13. Histamines (2nd gen) 14. Migraine 15. Aspirin 16. DMARD (anti-rheumatic) 17. UA synthesis inhibitors 18. Asthma 19. SMR – • Repolarizing blockers • Directly acting agents • Long-acting 20. Lignocaine 21. Techniques of anaesthesia (spinal) 22. Peptic ulcer 23. Anti-emetic prokinetic drugs 24. Laxatives (drugs for constipation) 25. Apparent vol of distribution 26. Plasma protein binding 27. Tdm 28. Plateau principle 29. Plasma protein binding 30. Bio transformation phases 31. Therapeutic window and index 32. Teratogenicity 33. Atropine 34. Alpha and beta blocker classification 35. Physostigmine and neostigmine 36. Mast cell stabilizer 37. Allopurinol 38. Xanthine oxidase inhibitor 39. Uricosuric drug 40. Cox 2 inhibitor 41. Antihistamines classification *Endocrine* (10 marks) 1. Classify corticosteroids (moa, kinetics, actions, uses,adverse effects) 2. ⁠prednisolone 3. ⁠classify insulin preparation 4. ⁠regular insulin 5. ⁠DKA management 6. ⁠insulin regimen and insulin resistance 7. ⁠classify oral hypoglycemic 8. ⁠sulfonylurease 9. ⁠metformin 10. ⁠classify oral contraceptives pills 11. ⁠emergency contraceptives (5 marks) 1. Bromocriptine 2. ⁠propylthiouracil 3. ⁠thyroid storms 4. ⁠carbinazol 5. ⁠insulin analogue 6. ⁠GLP-1 agonist 7. ⁠sitagliptine 8. ⁠anabolic steroids 9. ⁠finasteride 10. ⁠SERM 11. ⁠clomiphene citrate 12. ⁠Aromatase inhibitors 13. ⁠mefipristone 14. ⁠bisphosphonates *APPLIED & miscellaneous* 1. Indication of insulin in type-2 DM 2. ⁠⁠SGLT-2 inhibitors 3. ⁠tamoxifen 4. ⁠rationale behind combining estrogen and progesterone in OTC 5. ⁠uterine relaxants( trocholitics) & stimulates 6.Pharcogenomics 7. Pharmacoeconomics 8. Drugs in special situations (confirm) 9. Good Clinical Practice (wre majorly about drug