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📅 Phase II MBBS 2026 - Final Sessional Exam Study Plan

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🗓️ Exam Schedule (Theory)

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📚 Subject Portions

💊 Pharmacology (200 marks total)

• General Pharmacology
• ANS (Autonomic Nervous System)
• CNS (Central Nervous System)
• CVS (Cardiovascular System)
• Blood
• Diuretics
• Autacoids
• Respiratory System

• GIT
• Hormones
• Antibiotics
• Chemotherapy
• Miscellaneous

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🔬 Pathology (200 marks total)

• General Pathology
• Haematology (including Clinical Pathology)

• Systemic Pathology

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🦠 Microbiology (200 marks total)

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🗺️ Day-by-Day Study Plan (23 June - 12 July)

Phase 1: Pharmacology Focus (23 June - 3 July)

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Phase 2: Pathology Focus (4 July eve - 7 July)

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Phase 3: Microbiology Focus (8 July eve - 12 July)

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⭐ High-Yield Priorities

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📋 MBBS Phase II Sessional 2026 — Master Study Checklist

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⚠️ UPCOMING DEADLINES AT A GLANCE

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📅 DAY-BY-DAY TIMETABLE + CHECKLIST

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🟡 23 June (Tuesday) — TODAY

Morning/afternoon: free time / rest 5:00 PM onwards — START internal exam topics

• Anti-TB drugs — START (INH, Rifampicin, Pyrazinamide, Ethambutol, Streptomycin — mechanisms + side effects)
• Antimalarial drugs — START (Chloroquine, Primaquine, Artemisinins, Mefloquine)

Goal: just begin, not finish. Read and make quick notes.

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🟡 24 June (Wednesday) — Internal Exam Prep continues

• Antifungal drugs (Azoles, Amphotericin B, Echinocandins, Griseofulvin)
• Antiviral drugs (Acyclovir, Oseltamivir, NRTIs, NNRTIs, Protease inhibitors — broad overview)

• Antihelminthic drugs (Albendazole, Mebendazole, Ivermectin, Praziquantel, Diethylcarbamazine)
• Antiamoeba drugs (Metronidazole, Diloxanide, Chloroquine for amoeba)
• Antiprotic (Antiprotozoal — Metronidazole for Giardia/Trichomonas, Sodium stibogluconate for Leishmania, Pentamidine)

• Full revision pass of all internal exam topics
• Make a single-page drug list with mechanism + key side effect for each class

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🟡 25 June (Thursday) — Internal Exam Revision + Sessional Starts

• Quick revision of all 27 June internal topics (2nd pass)
• Flashcard-style recall: cover answer, say mechanism aloud

• General Pharmacology — Pharmacokinetics (absorption, distribution, metabolism, excretion)
• General Pharmacology — Pharmacodynamics (receptors, dose-response, drug interactions, adverse effects)
• General Pharmacology — Special topics (bioavailability, first-pass, half-life, steady state)

• ANS — Cholinergic drugs (direct + indirect acting, anticholinesterases)
• ANS — Anticholinergic drugs (atropine, scopolamine, uses)

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🟡 26 June (Friday) — Sessional Pharma Paper I continued

• ANS — Adrenergic agonists (adrenaline, noradrenaline, dopamine, dobutamine, salbutamol)
• ANS — Adrenergic antagonists (alpha blockers, beta blockers — classify + uses)
• CNS — Sedatives, hypnotics, anxiolytics (BZDs, Z-drugs, barbiturates)

• CNS — Antiepileptics (phenytoin, valproate, carbamazepine, levetiracetam — mechanism + uses)
• CNS — Antipsychotics (typical vs atypical, side effects including EPS)

• CNS — Antidepressants (TCAs, SSRIs, SNRIs, MAOIs — classify + key side effects)
• Quick revision of all ANS + CNS covered so far

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🔴 27 June (Saturday) — INTERNAL PHARMA EXAM

• Anti-TB: First line vs second line, DOT, side effects (optic neuritis, peripheral neuropathy, hepatotoxicity, ototoxicity)
• Antimalarials: chloroquine resistance, primaquine for G6PD, artemisinin combination therapy
• Antifungal: azole mechanism (ergosterol synthesis), Ampho B side effects (nephrotoxicity)
• Antiviral: NRTIs vs NNRTIs, Acyclovir for herpes, oseltamivir for influenza
• Antihelminth: choose correct drug for which worm
• Antiamoeba + Antiprotozoal: Metronidazole MOA, Leishmania drugs
• Antiprotic (Antipruritic/Antiprotozoal): review anything unclear

• Continue Sessional Pharma Paper I — CVS drugs: antihypertensives (CCBs, ACEi, ARBs, diuretics, beta blockers)

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🟡 28 June (Sunday) — Sessional Pharma Paper I (CVS, Blood, Diuretics, Autacoids)

• CVS — Antiarrhythmics (classify Vaughan Williams, amiodarone, digoxin)
• CVS — Antianginals (nitrates, ranolazine, ivabradine)
• CVS — Antihyperlipidaemics (statins, fibrates, ezetimibe, PCSK9 inhibitors)

• Blood — Anticoagulants (heparin, warfarin, DOACs — mechanisms + reversal)
• Blood — Antiplatelets (aspirin, clopidogrel, GPIIb/IIIa inhibitors)
• Blood — Thrombolytics + haematinics (iron, B12, folic acid, erythropoietin)

• Diuretics — full classification + mechanisms (thiazides, loop, K-sparing, carbonic anhydrase inhibitors)
• Autacoids — Histamine, antihistamines (H1 vs H2), serotonin, 5-HT drugs, prostaglandins, NSAIDs, COX-2 inhibitors

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🟡 29 June (Monday) — Sessional Pharma Paper I (Respiratory) + Paper I Full Revision

• Respiratory — Bronchodilators (beta-2 agonists, anticholinergics, methylxanthines)
• Respiratory — Anti-asthmatic (corticosteroids inhaled, cromones, leukotriene antagonists)
• Respiratory — Antitussives, expectorants, mucolytics

• Revise General Pharmacology (quick)
• Revise ANS (quick)
• Revise CNS (quick)
• Revise CVS (quick)
• Revise Blood + Diuretics (quick)
• Revise Autacoids + Respiratory (quick)
• Practice writing 5-mark and 10-mark answers for Paper I topics

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🟡 30 June (Tuesday) — Sessional Pharma Paper I Final Revision + Paper II Start

• Mock self-test: write 3 long answers + 5 short answers from Paper I topics
• Check and fill gaps from mock test

• GIT drugs — Antacids, PPIs, H2 blockers, prokinetics, antiemetics, laxatives, antidiarrhoeals
• Hormones — Insulin types + OHAs (sulfonylureas, biguanides, SGLT2i, DPP4i, GLP1 analogues)

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🔴 1 July (Wednesday) — Sessional Pharma Paper I — LAST DAY REVISION

• Hormones continued — Thyroid drugs (PTU, carbimazole, levothyroxine), corticosteroids, sex hormones, oral contraceptives, oxytocin, ADH
• Antibiotics overview (for Paper II) — Penicillins, Cephalosporins, Carbapenems, Macrolides, Tetracyclines, Aminoglycosides, Fluoroquinolones, Glycopeptides

• Final revision of ALL Paper I topics — quick scan notes only
• Rest by 9 PM, good sleep

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🔴 2 July (Thursday) — PHARMACOLOGY PAPER I EXAM

Topics: General Pharma, ANS, CNS, CVS, Blood, Diuretics, Autacoids, Respiratory

• Morning: light revision of weak areas only
• Eat well, sleep early the night before
• ✅ EXAM

• Chemotherapy — Anticancer drugs (alkylating agents, antimetabolites, vinca alkaloids, taxanes, targeted therapy, hormonal therapy)

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🟡 3 July (Friday) — Sessional Pharma Paper II Revision

• Antibiotics — detailed (mechanism, resistance, spectrum for each class — this is high yield)
• Anti-TB, Antimalarial, Antifungal, Antiviral (these overlap with your internal — revise quickly)

• Chemotherapy (continued) — detailed revision
• Miscellaneous — Immunosuppressants, chelating agents, drug dependence, ORS, vitamins

• Full Paper II revision — scan all topics
• Write 2-3 practice answers

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🔴 4 July (Saturday) — PHARMACOLOGY PAPER II EXAM

Topics: GIT, Hormones, Antibiotics, Chemotherapy, Miscellaneous

• Morning: light revision only
• ✅ EXAM

• General Pathology: Cell injury (reversible vs irreversible, apoptosis vs necrosis — types)

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🟡 5 July (Sunday) — Pathology Paper I (General Path + Haematology)

• General Pathology — Inflammation (acute vs chronic, mediators, granuloma formation)
• General Pathology — Wound healing, repair and regeneration
• General Pathology — Neoplasia (benign vs malignant, carcinogenesis, tumour markers)

• Haematology — Anaemias (iron deficiency, megaloblastic, haemolytic, aplastic — differentiate all)
• Haematology — Leukaemias (ALL, AML, CML, CLL — classify + key features)
• Haematology — Lymphomas (Hodgkin vs Non-Hodgkin, Reed-Sternberg cell)

• Haematology — Bleeding disorders (ITP, TTP, haemophilia, DIC, vWD)
• Clinical Pathology — LFT, RFT, CSF analysis, urine analysis

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🔴 6 July (Monday) — PATHOLOGY PAPER I EXAM

Topics: General Pathology + Haematology + Clinical Pathology

• Morning: quick revision of all Paper I topics, focus on definitions and morphology
• ✅ EXAM

• Systemic Pathology — CVS: IHD (MI — zones of necrosis, complications), hypertensive heart disease, rheumatic heart disease

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🟡 7 July (Tuesday) — Pathology Paper II (Systemic Pathology)

• Respiratory — Pneumonia (lobar vs broncho), TB pathology, COPD, lung carcinoma
• GIT — Peptic ulcer, Crohn's vs UC, liver cirrhosis, hepatitis, carcinomas

• Renal — Glomerulonephritis types, nephrotic vs nephritic, renal cell carcinoma, Wilms tumour
• Nervous system — Stroke pathology, demyelinating diseases, CNS tumours
• Endocrine — Diabetes complications, thyroid pathology (Hashimoto, Graves, tumours)

• Reproductive — Cervical carcinoma (CIN staging), endometrial, ovarian, breast carcinoma
• Full Paper II revision — scan morphology + key facts

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🔴 8 July (Wednesday) — PATHOLOGY PAPER II EXAM

Topics: Systemic Pathology

• Morning: revision of weakest systemic topics
• ✅ EXAM

• General Microbiology — Bacterial structure, growth curves, sterilization, disinfection

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🟡 9 July (Thursday) — Microbiology Paper I

• General Microbiology — Gram staining, culture media, bacterial genetics, bacteriophage
• Immunology — Innate vs adaptive immunity, complement, MHC, immunoglobulins, hypersensitivity types (I–IV)
• Immunology — Vaccines, immunodeficiency, autoimmunity

• Hospital Infection Control — Nosocomial infections, hand hygiene, isolation, sterilization methods, biofilm
• Infections of bloodstream + CVS (Bacteriology: Staph, Strep, Enterococcus endocarditis; Virology: CMV, EBV; Parasitology: malaria — 15+15+10+10 marks)

• Infections of skin/soft tissue/MSK (Staph pyoderma, gas gangrene, actinomycosis, fungi causing skin infections)
• STIs / Genitourinary (Gonorrhoea, Chlamydia, Syphilis, Trichomonas, HSV-2, HIV)

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🔴 10 July (Friday) — MICROBIOLOGY PAPER I EXAM

Topics: General Micro, Immunology, Hospital Infection Control, Bloodstream/CVS infections, Skin/MSK infections, STIs, AETCOM

• Morning: revision of General Micro + Immunology (45 marks — highest priority)
• ✅ EXAM

• Respiratory infections — TB (Mycobacterium, Koch's postulates, pathology, diagnosis), pneumococcal pneumonia, Influenza, COVID-19, Legionella, RSV

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🟡 11 July (Saturday) — Microbiology Paper II

• Respiratory infections (continued) — Aspergillus, PCP, viral pneumonias (60 marks block — highest yield)
• GIT + Hepatobiliary infections — Salmonella, Shigella, Cholera, E. coli, Rota/Noravirus, Hepatitis A/B/C/D/E (Bacteriology 35 marks + Virology 35 marks in Paper II)

• CNS infections — Bacterial meningitis (N. meningitidis, H. influenzae, S. pneumoniae), viral encephalitis (HSV, JE, Rabies), fungal (Cryptococcus), Tuberculoma
• Miscellaneous — Opportunistic infections (in HIV), Zoonosis (Brucella, Leptospira, Plague, Q fever, Anthrax), Congenital infections (TORCH)

• Anaerobic infections (Clostridium tetani, botulinum, perfringens), Oncogenic viruses (HPV, EBV, HBV, HTLV), Emerging diseases (Nipah, Zika, Ebola, Monkeypox)
• AETCOM (ethics in microbiology context — brief points)

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🔴 12 July (Sunday) — MICROBIOLOGY PAPER II FINAL REVISION

• Full Paper II revision — Respiratory + GIT/Hepatobiliary (60 marks — spend most time here)
• CNS + Miscellaneous (35 marks)
• Practice writing long answers on: TB, Cholera, Hepatitis B, HIV opportunistic infections
• Rest well

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🔴 13 July (Monday) — MICROBIOLOGY PAPER II EXAM

Topics: Respiratory infections, GIT/Hepatobiliary infections, CNS infections, Miscellaneous, AETCOM

• Morning: quick scan of notes only
• ✅ EXAM

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🟡 14–20 July — PRACTICALS PERIOD

• 15 July (Wed) — Practicals begin (Pharmacology A / Pathology B / Microbiology C)
• 16 July (Thu) — Practicals (Pharmacology C / Pathology A / Microbiology B)
• 17 July (Fri) — Practicals (Pharmacology B / Pathology C / Microbiology A)
• 20 July (Mon) — Practicals (Pharmacology D / Pathology G / Microbiology F)

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🔑 GOLDEN RULES

1. Never study new topics the night before an exam - only revise what you know
2. Microbiology Paper II has the heaviest mark load - Respiratory + GIT/Hepatobiliary = 60 marks
3. Your internal exam topics (Anti-TB, Antimalarials etc.) overlap with Pharma Paper II - revise them again on 3 July
4. Pathology Paper II (Systemic) is vast - stick to common long-question topics only, don't read everything
5. Sleep before exam days - no all-nighters

• Pharma Paper I - 3 days
• Pharma Paper II - 1 day
• Patho Paper I - 3 days
• Patho Paper II - 1 day
• Micro Paper II - 2 days
• Micro Paper I - 1 day

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📋 REVISED MASTER TIMETABLE + CHECKLIST

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⚠️ EXAM DATES (locked in)

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📅 CALENDAR ALLOCATION

Note: Patho Paper I actually gets 3 study slots: evening of 4 Jul + full day 5 Jul + morning of 6 Jul. Micro Paper II gets: evening of 8 Jul + full day 9 Jul + post-Paper I evening 10 Jul + 11 Jul + 12 Jul — which gives you more than 2 days but the bulk falls there.

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✅ DETAILED CHECKLIST

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🟡 23 June (Tue) — TODAY — Internal Exam Begins (5 PM onwards)

• 5:00 PM — Anti-TB drugs: INH, Rifampicin, Pyrazinamide, Ethambutol, Streptomycin (mechanism + key side effects)
• 7:00 PM — Antimalarial: Chloroquine, Primaquine, Artemisinins, Mefloquine (mechanism + resistance)
• Done for today — rest

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🟡 24 June (Wed) — Internal Exam Prep

• Antifungal: Amphotericin B, Azoles (Fluconazole, Itraconazole, Voriconazole), Echinocandins, Griseofulvin, Terbinafine
• Antiviral: Acyclovir/Valacyclovir, Oseltamivir, Antiretrovirals (NRTIs, NNRTIs, PIs, Integrase inhibitors) — broad overview

• Antihelminthic: Albendazole, Mebendazole, Ivermectin, Praziquantel, Diethylcarbamazine — which drug for which worm
• Antiamoeba: Metronidazole, Diloxanide furoate, Chloroquine (for hepatic amoebiasis)
• Antiprotozoal (Antiprotic): Metronidazole (Giardia, Trichomonas), Sodium stibogluconate/Miltefosine (Leishmania), Pentamidine

• Make a 1-page summary sheet — drug : mechanism : key side effect for all internal topics

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🟡 25 June (Thu) — Internal Exam Revision

• 2nd pass revision of Anti-TB (write out the side effects table: INH→peripheral neuropathy+hepatitis, Rifampicin→orange urine+hepatitis+enzyme inducer, PZA→hepatotoxicity+hyperuricaemia, Ethambutol→optic neuritis, Streptomycin→ototoxicity+nephrotoxicity)
• 2nd pass Antimalarials + Antifungals

• 2nd pass Antivirals + Antihelminthics + Antiamoeba + Antiprotozoal
• Practice writing: "Classify antifungals with mechanism and uses" — a common question format

• Rest / light reading only

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🟡 26 June (Fri) — Internal Exam Final Revision

• Final rapid scan of all internal topics using your summary sheet
• Recall test: cover the sheet and say aloud — drug class → drugs → MOA → side effects

• Address any gaps
• Rest well, sleep early

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🔴 27 June (Sat) — INTERNAL PHARMA EXAM

• Morning: light scan only — no new reading
• ✅ INTERNAL PHARMA EXAM

• General Pharmacology — Pharmacokinetics: absorption, distribution, metabolism (Phase I/II), excretion, half-life, Vd, protein binding, first-pass effect, bioavailability
• General Pharmacology — Pharmacodynamics: receptor types, agonist/antagonist, ED50/LD50, therapeutic index, dose-response curves

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🟡 28 June (Sun) — PHARMA PAPER I DAY 2

• General Pharmacology — Drug interactions (pharmacokinetic + pharmacodynamic), adverse drug reactions, drug monitoring
• ANS — Cholinergic: direct acting (Ach, Carbachol, Pilocarpine, Bethanechol), indirect acting (Neostigmine, Physostigmine, Organophosphates), Anticholinergics (Atropine, Scopolamine, Ipratropium, Glycopyrrolate)

• ANS — Adrenergic agonists (Adrenaline, Noradrenaline, Dopamine, Dobutamine, Salbutamol, Terbutaline, Phenylephrine, Clonidine)
• ANS — Adrenergic antagonists (Prazosin, Phentolamine; Propranolol, Atenolol, Metoprolol, Labetalol, Carvedilol)

• CNS — Sedatives/hypnotics/anxiolytics: BZDs (mechanism, uses, flumazenil reversal), Barbiturates, Z-drugs, Buspirone
• CNS — Antiepileptics: Phenytoin, Valproate, Carbamazepine, Phenobarbitone, Levetiracetam, Ethosuximide — drug of choice for each seizure type

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🟡 29 June (Mon) — PHARMA PAPER I DAY 3

• CNS — Antipsychotics: typical (Chlorpromazine, Haloperidol — EPS, tardive dyskinesia), atypical (Clozapine, Olanzapine, Risperidone — metabolic side effects)
• CNS — Antidepressants: TCAs (Imipramine — uses, anticholinergic SE), SSRIs (Fluoxetine — serotonin syndrome), SNRIs, MAOIs (tyramine interaction)
• CNS — Opioids (Morphine, Codeine, Fentanyl, Tramadol — mechanism, tolerance, naloxone reversal), General anaesthesia overview, NSAIDs/Paracetamol

• CVS — Antihypertensives: ACEi (Enalapril — cough, angioedema), ARBs, CCBs (Amlodipine/Nifedipine/Verapamil/Diltiazem), Beta blockers, Alpha blockers, Vasodilators (Hydralazine, Minoxidil), Centrally acting (Methyldopa, Clonidine)
• CVS — Antiarrhythmics: Vaughan Williams Class I–IV, Amiodarone (multi-class + side effects), Digoxin (mechanism, toxicity, uses)
• CVS — Antianginals: Nitrates (GTN mechanism), Beta blockers, CCBs, Ranolazine, Ivabradine

• Blood — Anticoagulants: Heparin (UFH vs LMWH, reversal with Protamine), Warfarin (mechanism, INR monitoring, reversal with Vit K/FFP), DOACs (Dabigatran, Rivaroxaban, Apixaban)
• Blood — Antiplatelets: Aspirin (irreversible COX inhibitor), Clopidogrel (ADP receptor), GPIIb/IIIa inhibitors
• Blood — Thrombolytics (Streptokinase, Alteplase) + Haematinics (Iron, B12, Folic acid, EPO)
• Diuretics: Loop (Frusemide), Thiazides (Hydrochlorothiazide), K-sparing (Spironolactone, Amiloride), CAi (Acetazolamide), Osmotic (Mannitol)

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🟡 30 June (Tue) — PHARMA PAPER I REVISION DAY

• Autacoids: Histamine + H1/H2 blockers (Cetirizine, Loratadine, Ranitidine, Cimetidine), Serotonin + 5-HT drugs (Ondansetron, Sumatriptan), Prostaglandins (Misoprostol, Dinoprostone), Bradykinin
• NSAIDs/COX-2 inhibitors: Aspirin, Ibuprofen, Indomethacin, Celecoxib — GI side effects, renal effects
• Respiratory: Beta-2 agonists (SABA vs LABA), Anticholinergics (Ipratropium, Tiotropium), Methylxanthines (Theophylline), ICS (Beclomethasone, Budesonide), Cromones, Leukotriene antagonists (Montelukast), Antitussives (Codeine, Dextromethorphan), Expectorants (Ammonium chloride), Mucolytics (Acetylcysteine)

• Quick scan: General Pharma
• Quick scan: ANS
• Quick scan: CNS
• Quick scan: CVS
• Quick scan: Blood + Diuretics
• Quick scan: Autacoids + Respiratory

• Write 3 practice long answers (pick: "Classify beta blockers with uses and side effects" / "Pharmacokinetics of Warfarin" / "Classify antiepileptics")
• Rest well

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🟡 1 July (Wed) — PHARMA PAPER II — 1 DAY

• GIT: Antacids (Mg/Al hydroxide), PPIs (Omeprazole — mechanism, SE), H2 blockers (Ranitidine), Prokinetics (Metoclopramide, Domperidone, Mosapride), Antiemetics (Ondansetron, Promethazine, Aprepitant), Laxatives (classify all types), Antidiarrhoeals (Loperamide, ORS)
• Hormones — Insulin: types (rapid/short/intermediate/long), OHAs (Sulfonylureas, Biguanides/Metformin, SGLT2i, DPP4i, GLP1 analogues, Thiazolidinediones) — mechanism + key SE each

• Hormones continued — Thyroid: Carbimazole/PTU (agranulocytosis SE), Levothyroxine; Corticosteroids: mechanism, HPA suppression, side effects; Sex hormones + OCPs + Emergency contraception; Oxytocin + Ergometrine; ADH (Desmopressin); GH/Somatostatin
• Antibiotics (for Paper II): Penicillins (mechanism + resistance by beta-lactamase), Cephalosporins (generations), Carbapenems, Monobactams, Macrolides (Azithromycin), Tetracyclines, Aminoglycosides (nephro+ototoxicity), Fluoroquinolones (tendon rupture), Glycopeptides (Vancomycin), Chloramphenicol (grey baby syndrome), Linezolid, Metronidazole

• Chemotherapy: Alkylating agents (Cyclophosphamide), Antimetabolites (Methotrexate, 5-FU, 6-MP), Vinca alkaloids (Vincristine, Vinblastine), Taxanes (Paclitaxel), Topoisomerase inhibitors, Targeted therapy (Imatinib, Trastuzumab), Hormonal (Tamoxifen, Letrozole)
• Miscellaneous: Immunosuppressants (Cyclosporine, Tacrolimus, Azathioprine), Chelating agents (Desferrioxamine, EDTA, Dimercaprol, Penicillamine), Drug dependence + withdrawal, Vitamins
• Anti-TB + Antimalarial + Antifungal + Antiviral + Antihelminth + Antiamoeba — quick revision only (you already know these from internal prep!)

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🔴 2 July (Thu) — PHARMACOLOGY PAPER I EXAM

• Morning: scan weakest topics only from Paper I
• ✅ PHARMACOLOGY PAPER I EXAM
• Evening: relax, no studying

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🟡 3 July (Fri) — PHARMA PAPER II REVISION (after Paper I exam — this is your actual 1 day for Paper II)

• Full day revision of all Paper II topics
• Focus: Antibiotics (highest yield) + Hormones (Insulin/OHAs always come)
• Write 2 practice answers
• Rest early

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🔴 4 July (Sat) — PHARMACOLOGY PAPER II EXAM

• Morning: light scan only
• ✅ PHARMACOLOGY PAPER II EXAM

• Cell injury: reversible vs irreversible, types of necrosis (coagulative, liquefactive, caseous, fat, fibrinoid, gangrenous), apoptosis vs necrosis
• Inflammation: acute (vascular + cellular events, chemical mediators), chronic inflammation (macrophage role), granuloma formation (TB, sarcoid, Crohn's)

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🟡 5 July (Sun) — PATHO PAPER I DAY 2

• Wound healing: primary vs secondary intention, factors affecting healing
• Neoplasia: benign vs malignant features, carcinogenesis (chemical/radiation/viral), oncogenes, tumour suppressor genes, tumour markers (AFP, CEA, PSA, CA125, CA19-9, HCG, LDH)

• Haematology — Anaemias: Iron deficiency (microcytic hypochromic, Serum iron↓, TIBC↑, ferritin↓), Megaloblastic (B12/Folate deficiency — hypersegmented neutrophils), Haemolytic (spherocytes, Coombs test), Aplastic, Sickle cell + Thalassaemias
• Haematology — Leukaemias: ALL (children, TdT+, Philadelphia chromosome occasionally), AML (Auer rods), CML (Philadelphia chromosome t(9;22), BCR-ABL), CLL (smudge cells, elderly)

• Haematology — Lymphomas: Hodgkin (Reed-Sternberg cells, stages, EBV association) vs Non-Hodgkin (B/T cell types, Burkitt — t(8;14), Follicular — t(14;18))
• Haematology — Bleeding disorders: ITP (platelets↓, normal PT/APTT), TTP (ADAMTS13 deficiency), Haemophilia A (Factor VIII) vs B (Factor IX), vWD, DIC (all clotting factors consumed)
• Clinical Pathology: LFT interpretation (bilirubin, ALT, AST, ALP, albumin), RFT (creatinine, BUN, GFR), Urine analysis (casts — RBC cast = GN, WBC cast = pyelonephritis, granular cast = ATN), CSF analysis (meningitis vs viral vs TB differences)

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🔴 6 July (Mon) — PATHOLOGY PAPER I EXAM

• Morning: revision focus — Haematology (highest yield, well-defined topics)
• ✅ PATHOLOGY PAPER I EXAM

• CVS Pathology: MI — zones (central necrosis, zone of injury, ischaemia), timeline of MI changes (gross + histological), complications; Hypertensive heart disease; Rheumatic heart disease (Aschoff bodies); Infective endocarditis

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🟡 7 July (Tue) — PATHO PAPER II — FULL DAY (your 1 day for Paper II)

• Respiratory: Pneumonia (lobar — stages: congestion/red hepatization/grey hepatization/resolution vs bronchopneumonia), TB pathology (Ghon focus, Ghon complex, miliary TB), COPD (emphysema — centriacinar vs panacinar, chronic bronchitis — Reid index), Carcinoma lung (squamous/adeno/small cell/large cell)
• GIT: Peptic ulcer (H. pylori, complications — perforation/haemorrhage/obstruction), Crohn's vs UC (classic comparison), Carcinoma colon (Duke's staging, APC gene), Appendicitis, Liver — cirrhosis (portal hypertension, varices, hepatorenal syndrome), Hepatitis B (chronic carrier, HCC), Hepatocellular carcinoma

• Renal: Glomerulonephritis — Nephrotic (Minimal change, FSGS, Membranous) vs Nephritic (IgA nephropathy, post-streptococcal GN, RPGN, Goodpasture's), Diabetic nephropathy (Kimmelstiel-Wilson nodules), Renal cell carcinoma (clear cell, paraneoplastic), Wilms tumour, Transitional cell carcinoma
• Endocrine: Diabetic complications (micro + macrovascular), Hashimoto thyroiditis (Hurthle cells), Graves disease (anti-TSH receptor Ab), Thyroid carcinoma (papillary — most common, orphan Annie eye nuclei; follicular; medullary — calcitonin; anaplastic)

• Nervous system: Stroke — haemorrhagic vs ischaemic, Berry aneurysm, Subdural vs epidural haematoma; Demyelinating (MS — periventricular plaques); CNS tumours (Glioblastoma — pseudopalisading necrosis, Meningioma, Acoustic neuroma, Medulloblastoma)
• Reproductive: Cervical carcinoma (CIN I/II/III, HPV 16/18, Koilocytes), Endometrial carcinoma (oestrogen-driven), Ovarian tumours (serous — most common, mucinous, dermoid cyst), Breast carcinoma (invasive ductal, BRCA1/2, Scirrhous, Paget's disease)

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🔴 8 July (Wed) — PATHOLOGY PAPER II EXAM

• Morning: revision of weakest systemic topics — 30 min each on Renal + Neuro
• ✅ PATHOLOGY PAPER II EXAM

• Respiratory infections: TB (Mycobacterium tuberculosis — Ziehl-Neelsen stain, Lowenstein-Jensen medium, Mantoux test, pathogenesis, diagnosis), Pneumococcal pneumonia, Klebsiella, Influenza, COVID-19, Legionella (Pontiac fever, silver stain, BCYE medium)

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🟡 9 July (Thu) — MICRO PAPER II DAY 2

• Respiratory continued: RSV (bronchiolitis in infants), Aspergillus (invasive in immunocompromised, Halo sign on CT), PCP (Pneumocystis jirovecii in HIV), viral pneumonias
• GIT infections — Bacteriology (35 marks in Paper II): Salmonella (Vi antigen, Widal test, rose spots), Shigella (Dysentery, Shiga toxin, no animal reservoir), Vibrio cholerae (rice water stools, El Tor biotype, TCBS medium), E. coli types (ETEC/EPEC/EHEC/EIEC/EAEC), H. pylori (CLO test, urease positive), Campylobacter, C. difficile (pseudomembranous colitis, CDT toxin)

• GIT infections — Virology (35 marks): Hepatitis A (faeco-oral, self-limiting, no carrier), Hepatitis B (HBsAg/HBeAg/anti-HBc serology — learn the window period, carrier state, HCC link), Hepatitis C (most common post-transfusion, chronicity), Hepatitis D (only with HBV), Hepatitis E (faeco-oral, dangerous in pregnancy), Rotavirus (commonest infantile diarrhoea), Norovirus (cruise ship outbreaks)
• Hepatobiliary: Entamoeba histolytica (liver abscess — anchovy sauce pus), Echinococcus (hydatid cyst — daughter cysts), Ascaris in biliary tree

• CNS infections: Bacterial meningitis (N. meningitidis — petechiae/purpura, Waterhouse-Friderichsen syndrome; H. influenzae type b — children; S. pneumoniae — adults/elderly; CSF findings for each), Viral encephalitis (HSV-1 — temporal lobe, Acyclovir; JE — Culex mosquito; Rabies — Negri bodies, Babes nodules), Fungal meningitis (Cryptococcus neoformans — India ink, latex agglutination), TB meningitis (cobweb clot in CSF)

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🔴 10 July (Fri) — MICROBIOLOGY PAPER I EXAM

Note: You only have 1 day for Micro Paper I — use the morning of this day

• Morning (6 AM – 12 PM) — ENTIRE Micro Paper I revision:
  • General Microbiology: Bacterial structure (cell wall — Gram+ vs Gram−, LPS, capsule, fimbriae, spores), growth curve (lag/log/stationary/decline), sterilization (autoclave, dry heat, filtration, radiation), disinfection (glutaraldehyde, formaldehyde), culture media types
  • Immunology: Innate (NK cells, complement, PAMPs/DAMPs), Adaptive (B cells/T cells, MHC I vs II, CD4 vs CD8), Antibody structure + classes (IgG/IgM/IgA/IgE/IgD), Complement (classical vs alternate vs lectin pathway), Hypersensitivity types I–IV (classic examples for each), Vaccines (live attenuated vs killed), Immunodeficiency (DiGeorge, Bruton, SCID, CGD)
  • Hospital Infection Control: Nosocomial infections (MRSA, VRSA, ESBL, carbapenem-resistant organisms), Hand hygiene (5 moments), isolation types (contact/droplet/airborne), HAIs (CAUTI, VAP, CLABSI, SSI)
  • Bloodstream/CVS infections: Staph aureus (MRSA, protein A, coagulase positive, toxins — TSST-1, exfoliatin), Strep viridans (subacute bacterial endocarditis, alpha-haemolytic), Enterococcus, Meningococcaemia (DIC), Malaria (Plasmodium — species differences, thick and thin smear, Giemsa stain), CMV (owl eye inclusions), EBV (heterophile antibodies, atypical lymphocytes)
  • Skin/MSK infections: Staph (impetigo, folliculitis, furuncle, carbuncle, scalded skin syndrome), Strep pyogenes (erysipelas, necrotising fasciitis, M protein), Gas gangrene (C. perfringens, α-toxin lecithinase), Actinomycosis (sulphur granules, Actinomyces israelii), Dermatophytes (Tinea — KOH mount), Sporothrix (rose thorn injury, cigar-shaped yeast)
  • STIs: Gonorrhoea (Gram-negative diplococci, oxidase positive, Thayer-Martin medium), Chlamydia (intracellular, RB→EB, most common STI), Syphilis stages (Treponema pallidum, VDRL/TPHA), Trichomonas vaginalis (wet mount, strawberry cervix), HSV-2 (Tzanck smear, multinucleated giant cells), HIV (CD4 count, ELISA + Western blot, window period)
  • AETCOM: Ethical principles in microbiology lab (confidentiality, informed consent for HIV testing, reporting of notifiable diseases)
• ✅ MICROBIOLOGY PAPER I EXAM (2 PM)

• Miscellaneous infections: Opportunistic infections in HIV (PCP, Cryptococcus, CMV retinitis, MAC, Toxoplasmosis, Candida oesophagitis — CD4 thresholds), Zoonosis (Brucella — Malta fever, undulant fever; Leptospira — Weil's disease, jaundice + renal failure; Plague — Y. pestis, Bubo; Q fever — Coxiella burnetii, rickettsiae; Anthrax — B. anthracis, cutaneous/pulmonary/GI; Rabies)

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🟡 11 July (Sat) — MICRO PAPER II REVISION

• Congenital infections: TORCH (Toxoplasma — hydrocephalus + intracranial calcifications; Rubella — cataracts + heart defects + deafness; CMV — periventricular calcifications; HSV — neonatal encephalitis; Syphilis — saddle nose + saber tibia + Hutchinson teeth)
• Anaerobic infections: C. tetani (tetanospasmin, spastic paralysis, risus sardonicus, opisthotonos), C. botulinum (flaccid paralysis, canned foods, SNAP-25), C. perfringens gas gangrene + food poisoning, C. difficile, Bacteroides fragilis (abdominal abscess, capsule important virulence factor)

• Oncogenic viruses: HPV (16/18 — cervical carcinoma, E6/E7 oncoproteins), EBV (Burkitt lymphoma, Hodgkin lymphoma, NPC), HBV (HCC), HTLV-1 (adult T-cell leukaemia/lymphoma), HHV-8 (Kaposi sarcoma), MCPyV (Merkel cell carcinoma)
• Emerging and Re-emerging diseases: Nipah virus (fruit bats, encephalitis, Kerala outbreaks), Zika virus (microcephaly, Aedes mosquito), Ebola (haemorrhagic fever, PPE, filamentous virus), Monkeypox/Mpox (orthopoxvirus, human-to-human transmission), COVID-19 (SARS-CoV-2, spike protein, ACE2 receptor), Hantavirus, Chikungunya, Dengue

• Full Paper II topic revision — Respiratory infections (highest yield) + Hepatitis serology (must be perfect)
• Write practice answers: "Pathogenesis and lab diagnosis of Cholera" / "Hepatitis B serology markers" / "Opportunistic infections in HIV"

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🟡 12 July (Sun) — MICRO PAPER II FINAL REVISION + REST

• Quick scan all Paper II topics — use notes/summary sheets only
• Focus extra time on: CNS infections + Miscellaneous (35 marks)
• Verify AETCOM points (5 marks — easy marks, don't miss)

• Rest, light reading only
• Sleep early

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🔴 13 July (Mon) — MICROBIOLOGY PAPER II EXAM

• Morning: scan notes only — NO new topics
• ✅ MICROBIOLOGY PAPER II EXAM

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🟡 14–20 July — PRACTICALS

• 15 July (Wed) — Practicals Day 1
• 16 July (Thu) — Practicals Day 2
• 17 July (Fri) — Practicals Day 3
• 20 July (Mon) — Practicals Day 4

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⭐ TOP PRIORITY TOPICS (most marks, most commonly asked)