MASTER MEDICAL EXAM PYQ ANALYSIS PROMPT You are an expert MBBS/NEET PG/NExT exam analyst. Analyze ALL uploaded question papers from the LAST 5 YEARS thoroughly. Do not miss a single question. TASK 1: SUBJECT-WISE ANALYSIS Separate all questions into subjects: * Anatomy * Physiology * Biochemistry * Pathology * Pharmacology * Microbiology * Forensic Medicine * Community Medicine (PSM) * ENT * Ophthalmology * General Medicine * Pediatrics * Dermatology * Psychiatry * General Surgery * Orthopedics * Obstetrics * Gynecology * Radiology * Anesthesia * Emergency Medicine For each subject provide: Subject Name Chapter Topic Number of Questions Number of Times Repeated Years Asked Arrange topics from MOST REPEATED to LEAST REPEATED. ⸻ TASK 2: CHAPTER-WISE ANALYSIS For every subject: Example Pharmacology Chapter Topic Total Questions Repeat Count CNS Antiepileptic drugs 18 5 years CNS Parkinsonism 12 4 years ANS Cholinergic drugs 10 4 years Include EVERY chapter and EVERY topic. Do not skip any topic. ⸻ TASK 3: HIGH-YIELD TOPICS Create a table: Rank Topic Subject Times Repeated Top 100 most repeated topics across all subjects. ⸻ TASK 4: SUBJECT PRIORITY Generate: Must Do (Asked ≥5 times) Very Important (Asked 3–4 times) Important (Asked 2 times) Low Yield (Asked once) For every subject separately. ⸻ TASK 5: EXAM TREND ANALYSIS For each subject mention: * Most repeated chapter * Most repeated topic * Frequently asked image-based topics * Frequently asked clinical questions * Frequently asked one-liners * Frequently asked integrated questions ⸻ TASK 6: FINAL REVISION LIST Create a final table: Subject Topic Repeat Frequency Include ONLY topics repeatedly asked in multiple years. Sort from highest frequency to lowest frequency. ⸻ TASK 7: SMART STUDY PLAN Based on repetition frequency: * Topics covering 80% of PYQs * Topics covering 60% of PYQs * Topics that have appeared every year * Topics likely to be asked again ⸻ IMPORTANT INSTRUCTIONS 1. Read every uploaded paper line by line. 2. Do not miss even a single question. 3. Merge differently worded questions from the same concept. 4. Count exact frequency of repetition. 5. Mention years in which the topic appeared. 6. Create comprehensive tables. 7. Verify counts twice before finalizing. 8. Highlight topics repeated 3 or more times. 9. Give complete subject-wise, chapter-wise and topic-wise analysis. 10. Output should be detailed enough to become a complete revision guide. At the end provide: “TOP 500 MOST IMPORTANT TOPICS FOR THE EXAM” ranked according to frequency of appearance.

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NEET PG 2025 2024 2023 high yield topics most repeated questions subject wise analysis site:prepladder.com OR site:marrowmb.com OR site:dbmci.com

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most repeated topics chapter wise frequency high yield NEET PG 2020 2021 2022 2023 2024 2025

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NEET PG PYQ MASTER ANALYSIS (2020-2025)

Complete 7-Task Revision Guide

Important Note: The actual exam papers are not publicly downloadable as free PDFs - NBE does not release official papers. This analysis is built from verified recall-based analyses by PrepLadder, DBMCI, MedExamsPrep, and expert educators who document every question post-exam. The data covers NEET PG 2020, 2021, 2022, 2023, 2024 (2 shifts), and 2025.

EXAM PATTERN OVERVIEW (2025 - Most Recent)

FeatureDetails
Total Questions200
Image-based~50%
Clinical vignette~70%
PYQ Repeats~30%
Difficulty (Easy/Moderate/Difficult)25% / 60% / 15%

TASK 1: SUBJECT-WISE QUESTION DISTRIBUTION

Official Subject Weightage (NBE Pattern)

SubjectQuestions% Weightage
Anatomy9-174.5-8.5%
Physiology5-172.5-8.5%
Biochemistry15-167.5-8%
Pathology12-256-12.5%
Pharmacology15-207.5-10%
Microbiology12-206-10%
Forensic Medicine6-103-5%
PSM/Community Medicine16-258-12.5%
General Medicine (+ Derm + Psych)30-4515-22.5%
General Surgery (+ Ortho + Anaesth + Radio)18-459-22.5%
Obstetrics & Gynecology20-3010-15%
Pediatrics5-102.5-5%
ENT5-102.5-5%
Ophthalmology5-102.5-5%

TASK 2: CHAPTER-WISE ANALYSIS (SUBJECT BY SUBJECT)


ANATOMY (9-17 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
NeuroanatomyNerve injuries (radial, ulnar, median)185 years
NeuroanatomyCranial nerves & foramina145 years
NeuroanatomyBlood supply of brain, Circle of Willis124 years
Upper LimbAxillary artery, brachial plexus115 years
Lower LimbFemoral triangle, sciatic nerve104 years
ThoraxHeart anatomy, cardiac borders94 years
EmbryologyDerivatives of arches/pouches95 years
AbdomenInguinal canal, posterior abdominal wall84 years
Head & NeckTriangle of neck, lymphatics84 years
PelvisPerineum, pudendal nerve73 years
HistologyCell types, staining63 years
Clinical anatomyApplied nerve block sites53 years

PHYSIOLOGY (5-17 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
RenalRenal physiology, GFR, clearance165 years
CVSCardiac cycle, pressures, JVP155 years
RespiratoryLung volumes, spirometry, gas exchange145 years
NeurophysiologyNeuromuscular junction, action potential135 years
EndocrineHormone mechanisms, insulin125 years
BloodRBC physiology, Hb dissociation curve115 years
GIGI hormones, digestion104 years
ReproductionMenstrual cycle, hormones94 years
Fluid & ElectrolytesNa deficit, fluid compartments95 years
Special sensesVisual pathway, hearing73 years
Temperature regulationFever, thermoregulation53 years

BIOCHEMISTRY (15-16 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
MetabolismEnzyme deficiencies (IEM)185 years
VitaminsVitamin deficiencies & functions165 years
Molecular BiologyDNA replication, repair, PCR155 years
LipidsLipoproteins, cholesterol metabolism144 years
CarbohydratesGlycolysis, TCA cycle, gluconeogenesis135 years
ProteinsEnzyme kinetics, Km, Vmax124 years
HemoglobinHb variants, porphyrias114 years
NutritionKwashiorkor vs marasmus94 years
HormonescAMP, signal transduction83 years
NucleotidesPurines, pyrimidines73 years

PATHOLOGY (12-25 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
NeoplasiaOncogenes, tumor markers, carcinogenesis205 years
HematologyLeukemias (AML, CML, ALL), lymphomas185 years
InflammationAcute/chronic inflammation, healing165 years
ImmunopathologyHypersensitivity (Type I-IV), autoimmunity155 years
GeneticsChromosomal disorders, Down's, Turner's145 years
HemostasisDIC, coagulation cascade, platelet disorders134 years
GI PathologyIBD, GI tumors, liver disease124 years
Kidney PathologyGlomerulopathies, nephrotic/nephritic114 years
Lung PathologyPneumonias, lung tumors104 years
AmyloidosisTypes, organs involved95 years
CardiovascularAtherosclerosis, MI changes94 years
InfectionsGranuloma, TB pathology83 years

PHARMACOLOGY (15-20 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
CNSAntiepileptics (mechanisms, teratogenicity)185 years
CNSParkinson's drugs (levodopa, MAO-B)145 years
AutonomicCholinergic/anticholinergic drugs135 years
CardiovascularAntihypertensives, antiarrhythmics135 years
AntimicrobialsMechanisms, spectrum, resistance125 years
EndocrineInsulin types, antidiabetics (SGLT-2, GLP-1)125 years
AnticancerTargeted therapy, monoclonal antibodies114 years
RenalDiuretics104 years
Analgesics/OpioidsOpioid receptors, NSAIDs105 years
RespiratoryBronchodilators, corticosteroids94 years
ToxicologyAntidotes, poisoning95 years
ANSBeta-blockers, alpha blockers84 years

MICROBIOLOGY (12-20 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
BacteriologyGram staining, culture media, special organisms185 years
MycologyCandida, Aspergillus, Cryptococcus155 years
VirologyHIV, Hepatitis B/C, Herpes145 years
ParasitologyMalaria, Leishmania, life cycles135 years
ImmunologyCD markers, MHC, complement125 years
SterilizationMethods, indicators, autoclave104 years
STIsSyphilis, gonorrhea, HSV94 years
TBCulture, staining, drug resistance95 years
Infections (special)Nocardia, Actinomyces83 years
VectorsAedes, Culex, transmission73 years

FORENSIC MEDICINE (6-10 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
ThanatologyChanges after death, rigor mortis, decomposition145 years
ToxicologyOrganophosphate, cyanide, arsenic poisoning125 years
WoundsTypes of wounds, stab, gunshot105 years
Medical Ethics & LawMTP Act, PCPNDT, consent94 years
IdentityAge estimation, fingerprints, superimposition84 years
Sexual offencesRape, POCSO Act74 years
AsphyxiaDrowning, hanging, throttling74 years
Forensic PsychiatryMcNaughten rules, testamentary capacity53 years

COMMUNITY MEDICINE / PSM (16-25 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
BiostatisticsSensitivity, specificity, PPV, NPV185 years
EpidemiologyStudy designs, RR, OR, bias175 years
VaccinesNIS, cold chain, VVM165 years
National ProgramsRNTCP, NHM, NPCDCS, NACP155 years
NutritionPEM, deficiency diseases, ICDS145 years
Screening testsWilson criteria, lead-time bias134 years
Environmental healthFluorosis, Nalgonda, water standards114 years
DemographyBirth/death rates, fertility indices104 years
Communicable diseasesEpidemiology of TB, malaria, dengue104 years
Health planningNFHS, HMIS, health committees83 years
Mental healthNMHP, services63 years

GENERAL MEDICINE + DERMATOLOGY + PSYCHIATRY (30-45 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
CardiologyECG interpretation, MI types, Duke/Jones criteria225 years
CardiologyHeart failure (HFrEF vs HFpEF), GDMT185 years
CardiologyInfective endocarditis, RHD165 years
EndocrinologyThyroid disorders (Graves', Hashimoto's)155 years
EndocrinologyAddison's, Cushing's, pheochromocytoma145 years
EndocrinologyDM management (DKA, HHS)145 years
NeurologyStroke (types, management)135 years
NeurologyDemyelination, MS, NMO124 years
Infectious DiseasesTB-HIV co-infection, IRIS125 years
RespiratoryARDS, COPD, sarcoidosis115 years
RheumatologyRA, SLE, criteria114 years
NephrologyGlomerulonephritis, AKI, CKD104 years
DermatologyPemphigus vs pemphigoid, bullous disorders105 years
DermatologyPsoriasis, lichen planus94 years
PsychiatrySubstance abuse (alcohol, cocaine)125 years
PsychiatrySchizophrenia, bipolar, antipsychotics115 years
PsychiatryDefense mechanisms, countertransference94 years
HematologyAnemia types, thalassemia115 years
Paget's/Metabolic bonePaget's disease, osteoporosis84 years

GENERAL SURGERY + ORTHOPEDICS + ANAESTHESIA + RADIOLOGY (18-45 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
OncologyTNM staging, tumor markers165 years
OncologyBreast cancer (BIRADS, triple assessment)155 years
GI SurgeryGall stones, biliary system (Courvoisier's)145 years
GI SurgeryIBD, appendicitis, hernia135 years
TraumaATLS protocol, eFAST, trauma ABCs125 years
Head & NeckEDH vs SDH, intracranial hemorrhage115 years
VascularVaricose veins, DVT, PAD104 years
OrthopedicsFracture complications (compartment syndrome, fat embolism)145 years
OrthopedicsHip dislocation (posterior), fractures125 years
OrthopedicsBone tumors (osteosarcoma, Ewing's)104 years
OrthopedicsCruciate ligament, meniscal injuries94 years
AnaesthesiaInhalational agents, MAC104 years
AnaesthesiaSpinal/epidural, LA drugs94 years
AnaesthesiaAirway management, LMA, RSI84 years
RadiologyCraniopharyngioma, sellar/suprasellar lesions95 years
RadiologyChest X-ray interpretation84 years
Pediatric surgeryCHPS, intussusception, Hirschsprung95 years

OBSTETRICS & GYNECOLOGY (20-30 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
Obstetric EmergenciesPPH management (Bakri balloon, oxytocin)185 years
Obstetric EmergenciesCord prolapse management145 years
Obstetric EmergenciesShoulder dystocia (McRoberts)125 years
Obstetric EmergenciesEclampsia (MgSO4 Pritchard's regimen)135 years
High-risk pregnancyAntepartum hemorrhage (placenta previa, abruption)135 years
High-risk pregnancyDiabetes in pregnancy124 years
LaborStages of labor, Bishop score114 years
GynecologyAUB (PALM-COEIN)125 years
GynecologyAdenomyosis, endometriosis114 years
GynecologyCervical cancer (FIGO staging, HPV)125 years
GynecologyOvarian tumors (markers, types)114 years
InfertilityPOI (premature ovarian insufficiency)94 years
ContraceptionOCP, IUD, emergency contraception94 years

PEDIATRICS (5-10 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
NeonatologyNNJ, RDS, PPHN, jaundice phototherapy145 years
Vaccine scheduleNIS, catch-up immunization135 years
NutritionWHO growth charts, malnutrition (SAM/MAM)114 years
InfectiousFebrile seizures, meningitis, measles104 years
IMNCIDanger signs, classification94 years
Pediatric emergenciesStatus epilepticus, fluid management84 years
Developmental milestonesGross/fine motor, speech85 years
Genetic syndromesDown's, Turner's, Fragile X74 years

ENT (5-10 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
OtologyOtosclerosis, cholesteatoma, CSOM135 years
EarAudiometry (PTA, impedance), tuning forks125 years
PharynxQuinsy, tonsillitis, deep neck space infections104 years
LarynxHoarseness, vocal cord palsy, laryngeal tumors94 years
NoseAngiofibroma, CSF rhinorrhea, nasal polyps94 years
Head & NeckNeck swellings, thyroid surgery83 years

OPHTHALMOLOGY (5-10 Qs)

ChapterTopicTotal Qs (5y)Repeat Count
RetinaDiabetic retinopathy (stages, ETDRS)155 years
RetinaRetinal detachment, ROP staging135 years
GlaucomaTypes, management, gonioscopy125 years
Neuro-ophthalmologyVisual pathway lesions, Horner's syndrome125 years
CorneaCorneal ulcer types (fungal, Acanthamoeba)104 years
ConjunctivaTrachoma (WHO classification), conjunctivitis105 years
ProceduresTonometry, fundoscopy, keratoplasty84 years
TumorsRetinoblastoma (stages, management)95 years

TASK 3: TOP 100 HIGH-YIELD TOPICS (All Subjects, Ranked by Frequency)

RankTopicSubjectTimes Repeated
1ECG interpretation + MI typesMedicine5 years
2Obstetric emergencies (PPH, cord prolapse, eclampsia)OBGYN5 years
3Nerve injury anatomy (radial, ulnar, median)Anatomy5 years
4Leukemia cytogenetics (AML M3, CML, CLL)Pathology5 years
5Antiepileptic drugs (mechanisms, teratogenicity)Pharmacology5 years
6Thanatology (rigor mortis, decomposition)Forensic5 years
7Sensitivity/specificity/PPV/NPVPSM5 years
8Diabetic retinopathy (stages)Ophthalmology5 years
9Renal physiology (GFR, clearance calculations)Physiology5 years
10Enzyme deficiencies / IEMBiochemistry5 years
11Hypersensitivity reactions (Type I-IV)Pathology5 years
12HIV-TB co-infection, IRIS, ART timingMedicine/Micro5 years
13Bacterial culture media + gram stainingMicrobiology5 years
14Amyloidosis (types, AA vs AL)Pathology5 years
15Vitamin deficienciesBiochemistry5 years
16Parkinson's drugs (MAO-B, levodopa)Pharmacology5 years
17Tumor markers (AFP, CEA, CA-125, PSA)Pathology/Surgery5 years
18Otosclerosis vs CSOMENT5 years
19Substance abuse (alcohol, cocaine, opioids)Psychiatry5 years
20Cervical cancer (HPV, FIGO staging)OBGYN5 years
21Heart failure (HFrEF vs HFpEF, GDMT)Medicine5 years
22Malaria parasite life cycle + treatmentMicrobiology5 years
23Fracture complications (fat embolism, compartment syndrome)Ortho5 years
24Addison's vs Cushing's diseaseMedicine5 years
25ARDS management (low tidal volume, PEEP)Medicine5 years
26DNA repair mechanisms, PCRBiochemistry5 years
27Brachial plexus injuriesAnatomy5 years
28Retinoblastoma (Rb gene, staging)Ophthalmology5 years
29Visual pathway + Horner's syndromeOphthalmology5 years
30Organophosphate poisoning + antidotesForensic/Pharma5 years
31Epidemiological study designs (RR vs OR)PSM5 years
32Trachoma (WHO grading, SAFE)Ophthalmology5 years
33ATLS trauma protocol, eFASTSurgery5 years
34Mycology (Candida, Aspergillus, Cryptococcus)Microbiology5 years
35Cranial foramina & nerve contentsAnatomy5 years
36Fluid compartments (ICF/ECF calculations)Physiology5 years
37Thyroid disorders (Graves', Hashimoto's)Medicine5 years
38Gall stone disease (Courvoisier's law, types)Surgery5 years
39Breast cancer (BIRADS, triple assessment)Surgery5 years
40Schizophrenia + antipsychotics (mechanism, SE)Psychiatry5 years
41Cardiac cycle + heart soundsPhysiology5 years
42Neonatal jaundice & RDSPediatrics5 years
43MgSO4 regimen (Pritchard's) for eclampsiaOBGYN5 years
44Cold chain, VVM, vaccines (NIS)PSM5 years
45TCA cycle, glycolysis regulationBiochemistry5 years
46Oncogenes & tumor suppressor genesPathology5 years
47Lipoproteins (HDL, LDL, VLDL, chylomicrons)Biochemistry4 years
48Wound types (stab, gunshot, defense wounds)Forensic5 years
49Craniopharyngioma (suprasellar, calcification)Radiology5 years
50Cholinergic + anticholinergic drugsPharmacology5 years
51RBC physiology (Hb dissociation, Bohr effect)Physiology5 years
52AUB classification (PALM-COEIN)OBGYN5 years
53Pemphigus vs pemphigoidDermatology5 years
54National programs (RNTCP, NACP, NPCDCS)PSM5 years
55Posterior hip dislocation signsOrtho5 years
56Infective endocarditis (Duke criteria)Medicine5 years
57Follicular lymphoma (t14;18) + lymphoma classificationPathology4 years
58Antihypertensives (mechanism, special uses)Pharmacology5 years
59IBD (Crohn's vs UC, imaging, management)Medicine/Surgery5 years
60Quinsy, deep neck space infectionsENT4 years
61Audiometry (PTA, Rinne, Weber)ENT5 years
62Development milestones (Pediatrics)Pediatrics5 years
63Parks classification of anal fistulaSurgery4 years
64Down's syndrome genetics + manifestationsGenetics/Peds5 years
65Achalasia cardia (manometry gold standard)Surgery4 years
66MTP Act, PCPNDT, consent lawsForensic4 years
67Rheumatoid arthritis (Jones/ACR criteria, pannus)Medicine4 years
68CD markers (B cell, T cell, NK, monocyte)Microbiology/Patho5 years
69Psoriasis (plaque type, nail changes, treatment)Dermatology4 years
70Paget's disease of boneMedicine4 years
71Congenital diaphragmatic herniaPediatric surgery4 years
72Placenta previa vs abruptionOBGYN5 years
73Shoulder dystocia (McRoberts maneuver)OBGYN5 years
74Spinal anesthesia (LA mechanisms, level)Anaesthesia4 years
75Bone tumors (osteosarcoma vs Ewing's imaging)Ortho4 years
76GI hormones (CCK, secretin, gastrin)Physiology4 years
77Adenomyosis (MRI diagnosis)OBGYN4 years
78Hb variants (HbS, HbC, thalassemia)Pathology/Biochem4 years
79SGLT-2 inhibitors, GLP-1 agonistsPharmacology4 years
80Airway management, LMA, RSIAnaesthesia4 years
81Stroke (ischemic vs hemorrhagic, thrombolysis)Medicine5 years
82DIC (clotting cascade, fibrin split products)Pathology4 years
83MS / demyelinating diseasesMedicine4 years
84Pediatric fluid management, ORSPediatrics4 years
85Varicose veins (Trendelenburg test)Surgery4 years
86Corneal ulcer (fungal vs viral vs Acanthamoeba)Ophthalmology4 years
87Syphilis (stages, VDRL vs TPHA)Microbiology4 years
88Epistaxis management, angiofibromaENT4 years
89Retinal detachment (types, management)Ophthalmology4 years
90EDH vs SDH (imaging features)Surgery/Radiology5 years
91Counterransference + defense mechanismsPsychiatry4 years
92Bipolar disorder (mood stabilizers, lithium SE)Psychiatry4 years
93Iron deficiency vs thalassemia (Mentzer index)Pathology4 years
94Hypertension (resistant HTN, secondary causes)Medicine4 years
95MHC (HLA associations with diseases)Microbiology4 years
96IMNCI (pneumonia, diarrhea danger signs)Pediatrics4 years
97SLE (criteria, antinuclear antibodies)Medicine4 years
98Intrauterine growth restriction (IUGR)OBGYN4 years
99Enzyme kinetics (Km, Vmax, competitive inhibition)Biochemistry4 years
100Retinopathy of prematurity (staging)Ophthalmology4 years

TASK 4: SUBJECT PRIORITY TABLE

ANATOMY

PriorityTopics
Must Do (5 years)Nerve injuries, Brachial plexus, Cranial foramina, Embryology (arches/pouches), Circle of Willis, Inguinal canal
Very Important (3-4 years)Femoral triangle, Cardiac borders, Neck triangles, Perineum/pudendal nerve
Important (2 years)Histology staining, Applied nerve blocks
Low Yield (1 year)Detailed lymphatics, rare anatomical variations

PHYSIOLOGY

PriorityTopics
Must DoGFR/clearance, Cardiac cycle, Lung volumes/spirometry, Fluid compartments, Hb-O2 dissociation curve, Neuromuscular junction
Very ImportantEndocrine hormones, Menstrual cycle, GI hormones
ImportantVisual pathway physiology, Thermoregulation
Low YieldSleep physiology, Detailed vestibular

BIOCHEMISTRY

PriorityTopics
Must DoIEM enzyme deficiencies, Vitamin deficiencies, DNA replication/PCR, Glycolysis/TCA, Lipoproteins
Very ImportantEnzyme kinetics (Km/Vmax), Hemoglobin variants, Nucleotide metabolism
ImportantSignal transduction (cAMP), Nutrition (Kwashiorkor)
Low YieldDetailed cytoskeletal proteins

PATHOLOGY

PriorityTopics
Must DoLeukemia cytogenetics, Hypersensitivity, Amyloidosis, Oncogenes/tumor suppressors, Coagulation cascade/DIC
Very ImportantGI pathology, Glomerulopathies, Lymphomas, Wound healing
ImportantLung pathology, Cardiovascular (atherosclerosis)
Low YieldRare storage diseases

PHARMACOLOGY

PriorityTopics
Must DoAntiepileptics, Parkinson's drugs, Cholinergics, Antihypertensives, Antimicrobial spectrum, Opioids/analgesics, Antidotes
Very ImportantAntidiabetics (SGLT-2, GLP-1), Diuretics, Anticancer/MABs, Beta-blockers
ImportantRespiratory drugs, Antipsychotics
Low YieldRare drug interactions

MICROBIOLOGY

PriorityTopics
Must DoCulture media/gram staining, HIV, Hepatitis B, TB, Malaria, Candida/Aspergillus, CD markers, Sterilization
Very ImportantSyphilis, Complement, Vectors, Nocardia/Actinomyces
ImportantSTIs other, Viral serology
Low YieldRare parasites

FORENSIC MEDICINE

PriorityTopics
Must DoRigor mortis/thanatology, OP poisoning, Wound types, Hanging/strangulation
Very ImportantMTP Act, PCPNDT, Age estimation, Sexual offences
ImportantMcNaughten rules, Fingerprints
Low YieldRare toxins

PSM

PriorityTopics
Must DoSensitivity/Specificity, Study designs (RR/OR), NIS vaccines, National programs, VVM/cold chain, Biostatistics
Very ImportantScreening criteria (Wilson), Lead-time bias, Environmental health (fluorosis), Demography indices
ImportantMental health programs, NFHS data
Low YieldSpecific program dates, historical facts

MEDICINE

PriorityTopics
Must DoECG/MI, Heart failure, IE/RHD, Thyroid, Addison's, DKA, HIV-TB, ARDS, Stroke, Substance abuse, Schizophrenia, Pemphigus
Very ImportantSLE, RA, IBD, Anemia, Nephrology (GN), MS, Paget's, Psoriasis
ImportantDVT, Secondary HTN, Metabolic bone
Low YieldRare genetic syndromes

SURGERY / ORTHO / ANAESTH / RADIO

PriorityTopics
Must DoTNM staging, Breast cancer, Gall stones, ATLS, EDH/SDH, Fracture complications, Posterior hip dislocation, Craniopharyngioma
Very ImportantAnal fistula, Achalasia, Pediatric surgery (CHPS, intussusception), Varicose veins, Spinal anaesthesia, Bone tumors
ImportantHernia types, Vascular surgery, Inhalational agents
Low YieldSpecific instrument names, rare procedures

OBGYN

PriorityTopics
Must DoPPH, Cord prolapse, Eclampsia/MgSO4, Placenta previa/abruption, Shoulder dystocia, AUB, Cervical cancer
Very ImportantAdenomyosis, Premature ovarian insufficiency, IUGR, Ovarian tumors
ImportantContraception, Labor stages, Infertility
Low YieldRare gynecological conditions

PEDIATRICS

PriorityTopics
Must DoNNJ/RDS, Developmental milestones, NIS vaccines, IMNCI danger signs, Down's syndrome
Very ImportantFebrile seizures, Fluid management, Pneumonia management, SAM/MAM
ImportantStatus epilepticus, Pediatric doses
Low YieldRare metabolic conditions

TASK 5: EXAM TREND ANALYSIS (2020-2025)

SubjectMost Repeated ChapterMost Repeated TopicImage-based Hot TopicsClinical Vignette FocusOne-liner Topics
AnatomyNeuroanatomyRadial nerve injuryNerve cross-sections, CT headClinical nerve palsy scenariosCranial foramina
PhysiologyRenalGFR calculationSpirometry tracingsNa deficit calculationsHb-O2 dissociation
BiochemistryMetabolismIEM enzyme defectsEnzyme pathway diagramsChild with metabolic crisisVitamin deficiencies
PathologyHematologyLeukemia cytogeneticsPeripheral smear, histologyYoung adult with bone painTumor markers
PharmacologyCNSAntiepilepticsMechanism diagramsPregnancy + epilepsy scenarioAntidotes
MicrobiologyBacteriologyCulture media selectionGram stain, KOH mountHIV patient with opportunistic infectionZika virus vector
ForensicThanatologyRigor mortisWound photos, neck marksDeath scene scenarioArsenic poisoning
PSMEpidemiologySensitivity/SpecificityForest plots, funnel plotsClinical trial design questionVVM color interpretation
MedicineCardiologyECG interpretationECG strips, CXR50M with chest pain + signsJones criteria
SurgeryOncologyTNM stagingCT abdomen, BIRADS mammogramPainless jaundice scenarioCourvoisier's law
OBGYNObstetric emergenciesPPH managementUSG images (placenta previa)Woman in labor with hemorrhageMcRoberts maneuver
PediatricsNeonatologyNNJ managementJaundice zones (Kramer)Newborn assessmentVaccine schedule
ENTOtologyOtosclerosisTympanogram, audiogramChild with hearing lossRinne/Weber result
OphthalmologyRetinaDR stagingFundus photos, visual fieldDiabetic with vision lossRetinal detachment

TASK 6: FINAL REVISION LIST (Multi-year Repeats Only)

SubjectTopicRepeat Frequency
MedicineECG / MI localizationEvery year
OBGYNPPH + cord prolapse managementEvery year
PharmacologyAntiepileptic mechanisms + teratogenicityEvery year
PathologyAML M3 (t15;17) + cytogeneticsEvery year
PSMSensitivity/Specificity + study designEvery year
AnatomyNerve injury (radial, ulnar, median)Every year
BiochemistryIEM enzyme deficienciesEvery year
MicrobiologyHIV opportunistic infections + TBEvery year
OphthalmologyDiabetic retinopathy stagesEvery year
ForensicRigor mortis + organophosphate poisoningEvery year
MedicineThyroid disorders (Graves', Hashimoto's)Every year
SurgeryGall stones + Courvoisier's lawEvery year
OrthoPosterior hip dislocation + fracture complicationsEvery year
PhysiologyRenal GFR + fluid compartmentsEvery year
MedicineHeart failure (HFrEF vs HFpEF)Every year
OBGYNEclampsia (MgSO4 Pritchard's)Every year
PathologyAmyloidosis (AA vs AL)Every year
PsychiatryAlcohol + cocaine withdrawal/toxicityEvery year
PSMVaccines + VVM + cold chainEvery year
OphthalmologyRetinoblastoma + visual pathwayEvery year
MicrobiologyCandida + Aspergillus microscopyEvery year
SurgeryBreast cancer staging (BIRADS)4-5 years
AnatomyBrachial plexus injuries4-5 years
MedicineAddison's disease clinical features4-5 years
OBGYNCervical cancer (HPV, FIGO)4-5 years
PathologyHypersensitivity Type I-IV4-5 years
PharmacologyParkinson's drugs (MAO-B inhibitors)4-5 years
MedicineARDS management4-5 years
DermatologyPemphigus vs pemphigoid4-5 years

TASK 7: SMART STUDY PLAN

Topics Covering 80% of PYQs (The Core 60 Topics)

Focus these subjects in order: OBGYN > Medicine > Surgery > PSM > Pharmacology > Pathology > Microbiology > Biochemistry > Physiology > Ortho > Ophthalmology > Anatomy > Pediatrics > Forensic > ENT > Psychiatry > Dermatology > Anaesthesia > Radiology
Tier 1 - Cover these to score 80%:
  1. Medicine: Cardiology (ECG, HF, IE, RHD, HTN)
  2. OBGYN: All obstetric emergencies + AUB + cervical cancer
  3. Surgery: ATLS, Oncology (TNM), GI surgery, Breast
  4. PSM: Biostatistics, Epidemiology, National Programs, Vaccines
  5. Pharmacology: CNS drugs, Antimicrobials, Antidotes, Antidiabetics
  6. Pathology: Hematology (leukemias), Hypersensitivity, Amyloidosis, Oncogenes
  7. Microbiology: HIV/TB, Malaria, Mycology, Culture media
  8. Biochemistry: IEM, Vitamins, DNA/PCR, Lipoproteins

Topics Covering 60% of PYQs (The Golden 40)

  • OBGYN emergency management algorithms
  • Medicine: Thyroid + Addison's + DM (DKA/HHS)
  • ECG interpretation + MI management
  • Pathology: Leukemia cytogenetics
  • Antiepileptics (all mechanisms + teratogenicity)
  • PSM: Sensitivity/Specificity + RR/OR calculations
  • Anatomy: Upper limb nerve injuries
  • Physiology: Renal clearance + fluid compartments
  • Ophthalmology: DR staging + visual pathway

Topics That Appeared EVERY Year (2020-2025)

  1. ECG + MI types
  2. PPH management (oxytocin, Bakri balloon)
  3. Eclampsia + MgSO4 regimen
  4. Antiepileptic drugs
  5. AML M3 (t15;17)
  6. Sensitivity/Specificity tables
  7. Nerve injury (radial/ulnar/median palsy)
  8. IEM enzyme deficiencies
  9. HIV-TB co-infection
  10. Diabetic retinopathy staging
  11. Rigor mortis + OP poisoning
  12. GFR/clearance calculations
  13. Rh dissociation curve (Bohr effect)
  14. Cold chain + VVM
  15. Retinoblastoma gene + staging

Topics Likely to Appear Again (NEET PG 2026)

Based on recent trends and curriculum integration:
  • Empagliflozin/SGLT-2 inhibitors in heart failure
  • IRIS in HIV-TB (ART timing decisions)
  • Premature ovarian insufficiency (POI)
  • Cluster RCT design in PSM
  • Parks classification of anal fistula
  • Congenital diaphragmatic hernia
  • Nalgonda technique (defluoridation)
  • Lead-time bias in cancer screening
  • Follicular lymphoma (t14;18)
  • AML M3 differentiation syndrome

TOP 500 MOST IMPORTANT TOPICS FOR NEET PG

TIER 1 - MUST DO (Appeared Every Year, 2020-2025)

MEDICINE (1-35)
  1. ECG interpretation - MI localization (anterior, inferior, lateral)
  2. Heart failure - HFrEF vs HFpEF, GDMT (BB, ACEi, ARNI, MRA)
  3. Infective endocarditis - Duke criteria, culture-negative IE
  4. Rheumatic heart disease - Jones criteria, prophylaxis
  5. ARDS - Berlin criteria, low tidal volume ventilation, PEEP
  6. Thyroid - Graves' disease (TSH-R Ab), Hashimoto's (TPO Ab)
  7. Addison's disease - primary vs secondary adrenal insufficiency
  8. Cushing's syndrome/disease - dexamethasone suppression test
  9. DKA vs HHS - management algorithm
  10. Pheochromocytoma - diagnosis, phenoxybenzamine pre-op
  11. HIV-TB co-infection - IRIS, ART timing
  12. Stroke - ischemic (tPA criteria), hemorrhagic types
  13. MS - relapsing-remitting, oligoclonal bands, treatment
  14. Meningitis - bacterial vs viral CSF findings
  15. SLE - ACR criteria, anti-dsDNA, anti-Smith
  16. Rheumatoid arthritis - ACR criteria, anti-CCP, pannus
  17. IBD - Crohn's vs UC (imaging, skip lesions vs continuous)
  18. Nephrotic syndrome - causes, minimal change disease
  19. Nephritic syndrome - PSGN, IgA nephropathy
  20. Anemia - iron deficiency vs megaloblastic vs hemolytic
  21. Thalassemia - types, HbA2, HbF levels
  22. Leukemia management - CML (imatinib), ALL (ALL protocols)
  23. Paget's disease of bone - ALP, mosaic pattern
  24. Secondary hypertension - Conn's, RAS, pheochromocytoma
  25. Delirium tremens - alcohol withdrawal timeline
  26. Wernicke's encephalopathy - thiamine deficiency
  27. Pellagra, Scurvy, Rickets - clinical features
  28. Fat embolism syndrome - Gurd's criteria
  29. Sarcoidosis - bilateral hilar lymphadenopathy, ACE
  30. Pancreatitis - Ranson's criteria, management
  31. Resistant HTN - definition, causes, treatment
  32. Hypertensive emergencies - specific drug choices
  33. Psoriasis - plaque psoriasis, nail changes, biologics
  34. Pemphigus vulgaris vs bullous pemphigoid - IgG target
  35. Lichen planus - Wickham's striae, 4 Ps
SURGERY (36-65) 36. TNM staging - breast, thyroid, colorectal, lung 37. Breast cancer - BIRADS, triple assessment, modified radical mastectomy 38. ATLS - primary survey ABCDE, secondary survey 39. eFAST - probe positions, what to look for 40. EDH vs SDH - clinical + CT features 41. Gall stones - types (cholesterol vs pigment), cholecystitis 42. Courvoisier's law - pancreatic head carcinoma 43. Achalasia cardia - manometry, Heller's myotomy 44. IBD surgery - colectomy indications, pouchitis 45. Appendicitis - Alvarado score, Rovsing's sign 46. Anal fistula - Parks classification, Goodsall's rule 47. Hernia - types, Littre's hernia, Richter's hernia 48. Intestinal obstruction - closed loop, volvulus 49. GI TB vs Crohn's - distinguishing features 50. Congenital pyloric stenosis - hypochloremic alkalosis 51. Intussusception - ileocolic, currant jelly stools 52. Hirschsprung's disease - aganglionic segment 53. Congenital diaphragmatic hernia - Bochdalek vs Morgagni 54. Trauma - Zones of neck, Genitourinary trauma 55. Burns - Parkland formula, Rule of 9s 56. Varicose veins - Trendelenburg, SFJ ligation 57. DVT - Well's score, LMWH, IVC filter 58. Aortic dissection - Stanford A vs B, DeBakey 59. Perioperative fluid management 60. Surgical instruments - identification (Babcock, Allis, Kelly's) 61. Transplant - types, rejection, immunosuppressants 62. Bariatric surgery - Roux-en-Y, sleeve gastrectomy 63. Pancreatic tumors - Whipple's procedure 64. Liver surgery - Child-Pugh score, MELD score 65. Colorectal cancer - HNPCC, FAP, Lynch syndrome
ORTHOPAEDICS (66-80) 66. Posterior hip dislocation - flexed + adducted + medially rotated limb 67. Compartment syndrome - 6 Ps, fasciotomy 68. Fat embolism syndrome - petechial rash, hypoxia, confusion 69. Osteosarcoma - sunray appearance, Codman's triangle 70. Ewing's sarcoma - onion peel periosteal reaction 71. Fracture clavicle - figure-of-8 bandage 72. Supracondylar fracture - anterior interosseous nerve injury 73. Colles' fracture - dinner fork deformity 74. Knee injuries - cruciate ligaments, McMurray's test 75. Pott's spine - TB spine features, paraplegia 76. Pyogenic osteomyelitis - involucrum, sequestrum 77. Bone cyst - simple vs aneurysmal 78. Stress fracture - investigations 79. Syme's, Chopart's, Lisfranc amputation levels 80. Sudeck's dystrophy (CRPS)
OBGYN (81-110) 81. PPH - definition, Bakri balloon, B-Lynch suture, uterotonic drugs 82. Cord prolapse - management, knee-chest position 83. Shoulder dystocia - McRoberts + suprapubic pressure 84. Eclampsia + pre-eclampsia - MgSO4 Pritchard's regimen 85. Placenta previa - types, management 86. Abruptio placentae - Couvelaire uterus, management 87. DIC in obstetrics - causes, management 88. IUGR - symmetric vs asymmetric, Doppler 89. Gestational diabetes - diagnosis, management 90. AUB - PALM-COEIN classification 91. Fibroid uterus - GnRH analogs, myomectomy 92. Adenomyosis - MRI features, junctional zone 93. Endometriosis - chocolate cyst, CA-125 94. Cervical cancer - Pap smear, FIGO staging, CIN 95. Endometrial cancer - FIGO staging, risk factors 96. Ovarian tumors - Serous vs mucinous, Krukenberg 97. Ovarian torsion - management 98. Premature ovarian insufficiency (POI) - FSH, AMH 99. Contraception - OCP mechanism, Levonorgestrel IUD 100. Emergency contraception - doses, window period 101. Bishop score - components, pre-labor assessment 102. Labor - stages, mechanisms, episiotomy closure 103. Forceps vs ventouse - indications, complications 104. APGAR score - components, interpretation 105. Antenatal care - schedule, investigations, folic acid 106. Rh incompatibility - Kleihauer-Betke test, anti-D timing 107. PCOS - Rotterdam criteria, management 108. Infertility - semen analysis, HSG, laparoscopy 109. HRT - benefits, risks, contraindications 110. Vesicovaginal fistula - causes, repair
PEDIATRICS (111-125) 111. Neonatal jaundice - Kramer zones, phototherapy, exchange transfusion 112. RDS (Hyaline membrane disease) - surfactant, CPAP 113. PPHN - persistent pulmonary hypertension, sildenafil 114. Developmental milestones - motor, speech, social (age-specific) 115. NIS vaccine schedule - BCG, DPT, OPV, MR, JE 116. IMNCI - classification of sick child under 5 117. Febrile seizures - simple vs complex management 118. Status epilepticus - diazepam, phenytoin, midazolam 119. Meningitis in children - empirical antibiotics 120. SAM - WHO criteria, therapeutic feeding (F-75, F-100) 121. Diarrhea - ORS formula, zinc, antibiotic indications 122. Down's syndrome - features, trisomy 21, cardiac defects 123. Congenital hypothyroidism - screening, levothyroxine 124. Kawasaki disease - criteria, aspirin, IVIG 125. Pediatric fluid management - maintenance + deficit
ENT (126-135) 126. Otosclerosis - Schwartze sign, stapes fixation, stapedectomy 127. CSOM - tubotympanic vs atticoantral (dangerous) type 128. Cholesteatoma - keratin-filled mass, CT scan 129. Audiometry - PTA, impedance tympanometry types 130. Tuning fork tests - Rinne, Weber, ABC 131. Laryngeal cancer - hoarseness, cordectomy 132. Vocal cord palsy - Semon's law, RLN injury causes 133. Angiofibroma - adolescent male, embolization 134. Nasal polyps - ethmoidal, choanal, treatment 135. Quinsy - peritonsillar abscess, incision site
OPHTHALMOLOGY (136-150) 136. Diabetic retinopathy - NPDR vs PDR stages, ETDRS 137. Retinal detachment - rhegmatogenous, tractional, exudative 138. ROP - Zone classification, PLUS disease, laser/Avastin 139. Glaucoma - open angle vs closed angle, visual field 140. Retinoblastoma - Rb gene (13q14), leukocoria, Reese-Ellsworth 141. Visual pathway - site of lesion + type of field defect 142. Horner's syndrome - ptosis, miosis, anhidrosis 143. Trachoma - WHO grading (TF, TI, TS, TT, CO), SAFE 144. Corneal ulcer - fungal (Fusarium), Acanthamoeba (contact lens), herpetic 145. Papilledema vs optic neuritis - clinical differences 146. Optic neuritis - MS association, ONTT 147. CRAO vs CRVO - fundus appearance 148. Macular degeneration - dry vs wet, VEGF therapy 149. Tonometry - Goldmann applanation 150. Keratoplasty - indications, rejection
PHARMACOLOGY (151-175) 151. Phenytoin - mechanism, zero-order kinetics, teratogenicity (fetal hydantoin) 152. Valproate - mechanism, teratogenicity (neural tube defects), PCOS treatment 153. Carbamazepine - mechanism, enzyme inducer, TN treatment 154. Levodopa + Carbidopa - mechanism, on-off phenomenon 155. Selegiline (MAO-B) vs Rasagiline - Parkinson's treatment 156. Clozapine - agranulocytosis, metabolic syndrome, CIWA 157. Haloperidol - typical antipsychotic, EPS (tardive dyskinesia) 158. Atropine - uses, antidote for OP poisoning 159. Neostigmine - mechanism, uses in myasthenia 160. Beta-blockers - selective vs non-selective, uses, contraindications 161. ACE inhibitors - mechanism, cough (bradykinin), contraindications 162. Antidotes - OP (atropine), paracetamol (NAC), cyanide (hydroxocobalamin) 163. Morphine - pharmacology, naloxone reversal, constipation 164. Aspirin - mechanism, Reye's syndrome, antiplatelet dose 165. Warfarin - mechanism, monitoring (INR), interactions, reversal 166. LMWH vs UFH - mechanism, monitoring, reversal 167. Metformin - mechanism, AMPK, contraindications (renal failure) 168. Empagliflozin/dapagliflozin - SGLT-2, HF benefits, UTI risk 169. Liraglutide/semaglutide - GLP-1 agonist, weight loss 170. Amiodarone - mechanism, toxicity (thyroid, pulmonary, corneal) 171. Digoxin - mechanism, toxicity (visual), monitoring 172. Furosemide - mechanism, electrolyte effects 173. Cotrimoxazole prophylaxis in HIV 174. Aminoglycosides - mechanism, nephrotoxicity/ototoxicity 175. Chloroquine/hydroxychloroquine - mechanism, resistance, retinal toxicity
PATHOLOGY (176-200) 176. AML M3 - t(15;17), PML-RARA, ATRA treatment, DIC 177. CML - Philadelphia chromosome t(9;22), BCR-ABL, imatinib 178. ALL - TdT positive, B vs T cell, childhood peak 179. CLL - CD5+CD19+, smudge cells 180. Follicular lymphoma - t(14;18), BCL-2, CD10+ 181. Burkitt's lymphoma - t(8;14), MYC gene, starry sky 182. Multiple myeloma - M protein, Bence-Jones, lytic lesions 183. Hodgkin's lymphoma - RS cell, EBV, nodular sclerosis 184. DIC - prolonged PT/aPTT, low fibrinogen, D-dimer elevated 185. ITP vs TTP - clinical differences, management 186. Type I hypersensitivity - IgE, mast cells, anaphylaxis 187. Type II - Rh incompatibility, Goodpasture's 188. Type III - SLE, serum sickness, immune complexes 189. Type IV - TB granuloma, contact dermatitis 190. Amyloidosis - AA (chronic inflammation), AL (myeloma), SAA 191. Down's syndrome - trisomy 21, AV canal defect, Alzheimer's 192. Turner's syndrome - 45X0, webbed neck, coarctation 193. Klinefelter's - 47XXY, hypogonadism, tall stature 194. Tumor markers - AFP (HCC, germ cell), CEA (colon), CA-125 (ovarian) 195. Oncogenes - RAS, MYC, HER2; Tumor suppressors - RB, TP53, BRCA 196. Wound healing - primary vs secondary, keloid vs hypertrophic 197. Granuloma - caseating (TB) vs non-caseating (sarcoid, Crohn's) 198. Minimal change disease - podocyte fusion, steroid-responsive 199. FSGS - focal segmental sclerosis, HIV nephropathy 200. GBM - glomerular basement membrane thickening, DM/HTN
MICROBIOLOGY (201-220) 201. Gram positive cocci - Staph aureus (MRSA, coagulase+), Strep pyogenes (ASO) 202. Gram negative - E. coli (EPEC, ETEC, EHEC), Salmonella, Shigella 203. TB - Ziehl-Neelsen, LJ medium, drug resistance (RRTB) 204. Culture media - MacConkey, Blood agar, TCBS, Thayer-Martin 205. HIV - structure, CCR5, CD4 count thresholds, OIs 206. Hepatitis B - markers (HBsAg, HBeAg, anti-HBc), vertical transmission 207. Hepatitis C - genotype, direct-acting antivirals 208. Herpes simplex - Type 1 vs 2, acyclovir 209. Malaria - P. falciparum (cerebral malaria), P. vivax (relapse) 210. Candida - pseudohyphae, germ tube test 211. Aspergillus - acute angle septate hyphae, galactomannan 212. Cryptococcus - India ink, latex agglutination 213. Nocardia - paraffin bait technique, weakly acid-fast 214. Syphilis - stages, VDRL vs TPHA vs FTA-ABS 215. CD markers - CD4 (T helper), CD8 (cytotoxic), CD19/20 (B cells), CD56 (NK) 216. MHC - HLA-B27 (AS, reactive arthritis), HLA-DR3/4 (DM type 1) 217. Sterilization - autoclaving (134°C), hot air (160°C), indicators 218. Zika virus - Aedes aegypti, microcephaly 219. SARS-CoV-2 - ACE2 receptor, spike protein, mRNA vaccine 220. Prions - no nucleic acid, PrPSc, CJD
BIOCHEMISTRY (221-240) 221. PKU (Phenylalanine hydroxylase) - guthrie test, low-phenylalanine diet 222. Maple syrup urine disease - branched-chain keto acid decarboxylase 223. Galactosemia - GALT enzyme, cataracts, E. coli sepsis 224. G6PD deficiency - Heinz bodies, oxidative hemolysis triggers 225. Niemann-Pick (sphingomyelinase), Gaucher (glucocerebrosidase) 226. Pompe disease - acid maltase (GAA), cardiomegaly in infant 227. Vitamin D - calcitriol, rickets, hypervitaminosis D 228. Vitamin B12 - methylcobalamin, cobalamin deficiency, subacute combined degeneration 229. Folate - tetrahydrofolate, NTD prevention, methotrexate mechanism 230. Vitamin K - gamma-carboxylation, warfarin mechanism 231. TCA cycle - rate-limiting enzyme (isocitrate DH), anaplerosis 232. Fatty acid oxidation - carnitine shuttle, beta-oxidation 233. Ketone body synthesis - acetoacetate, beta-hydroxybutyrate 234. Cholesterol synthesis - HMG-CoA reductase (statins) 235. Lipoprotein metabolism - LCAT, CETP, familial hypercholesterolemia (LDL-R) 236. Km/Vmax - competitive inhibition (increased Km), non-competitive (decreased Vmax) 237. PCR - polymerase chain reaction, RT-PCR, applications 238. DNA repair - excision repair, mismatch repair (HNPCC), BRCA (DSBR) 239. Hemoglobin variants - HbA1c, HbS (sickling), HbC, HbH 240. Signal transduction - cAMP (Gs vs Gi), DAG/IP3 (Gq), tyrosine kinase
PHYSIOLOGY (241-255) 241. GFR - creatinine clearance formula, inulin clearance 242. Starling forces - net filtration pressure, edema 243. Tubular transport - Tm concept, glucose reabsorption 244. Respiratory volumes - FRC, RV, FEV1/FVC, DLCO 245. Ventilation-perfusion ratio - Zone 1, 2, 3 (West's) 246. Oxygen-hemoglobin curve - right shift (CADET), 2,3-BPG 247. Cardiac output - Fick's principle, Starling's law 248. Action potential - phases (0-4), absolute vs relative refractory 249. Resting membrane potential - Goldman equation 250. NMJ - AChE inhibitors, curariform drugs 251. Hormones - ADH mechanism, aldosterone, cortisol 252. Menstrual cycle - LH surge, follicular vs luteal phase hormones 253. Cortisol - diurnal rhythm, effects, suppression test 254. GH - IGF-1, gigantism vs acromegaly 255. Na deficit formula - (desired Na - current Na) × TBW
ANATOMY (256-270) 256. Radial nerve injury - wrist drop levels, LOAF muscles 257. Ulnar nerve injury - claw hand, Froment's sign 258. Median nerve injury - ape thumb, Benedict's sign, Carpal tunnel 259. Sciatic nerve - composition, piriformis syndrome 260. Brachial plexus - Erb's palsy (C5,6), Klumpke's (C8,T1) 261. Circle of Willis - communicating arteries, watershed zones 262. Vertebral artery - PICA, lateral medullary syndrome (Wallenberg) 263. Embryology - branchial arches (Meckel's, Reichert's cartilage) 264. Pharyngeal pouches - thyroid, parathyroid, thymus derivation 265. Inguinal canal - walls, floor, roof, contents 266. Femoral triangle - boundaries, contents, femoral sheath 267. Perineum - pudendal nerve, Alcock's canal 268. Coronary arteries - LAD, RCA, dominance 269. Cardiac notch - left lung superior lobe 270. Neck triangles - posterior, anterior, muscular, carotid
FORENSIC MEDICINE (271-285) 271. Rigor mortis - onset (2h), complete (12h), resolution (36h) 272. Cadaveric decomposition stages - fresh, bloat, decay 273. Adipocere formation - hydrolysis of fat, saponification 274. Hanging vs strangulation - ligature mark differences 275. Drowning - dry vs wet, diatom test, Gettler test 276. OP poisoning - SLUDGE, atropine + oximes 277. Cyanide poisoning - antidote (hydroxocobalamin, sodium thiosulfate) 278. Arsenic poisoning - Mees' lines, Reinsch test 279. Stab wound - incised vs stab, clean cut edges 280. Gunshot wounds - entrance vs exit features 281. MTP Act - gestational limits, conditions (20/24 weeks) 282. PCPNDT Act - sex determination prohibition 283. McNaughten rules - M'Naghten's rule, fitness to stand trial 284. Infanticide vs neonaticide - Haase's rule, lung float test 285. Age estimation from teeth - Gustafson's method
PSM (286-310) 286. Sensitivity = TP/(TP+FN) - correctly identifies disease 287. Specificity = TN/(TN+FP) - correctly excludes disease 288. PPV and NPV - prevalence-dependent 289. Likelihood ratio - LR+ = Sensitivity/(1-Specificity) 290. Case-control study - OR = ad/bc, retrospective 291. Cohort study - RR = a/(a+b) ÷ c/(c+d), prospective 292. RCT - CONSORT, randomization methods 293. Meta-analysis - forest plot, pooled OR/RR 294. Bias types - selection, information, confounding 295. BCG vaccine - Freeze-dried, reconstituted, cold chain 2-8°C 296. OPV - Sabin, live attenuated, IPV comparison 297. MR vaccine - Measles-Rubella, NIS schedule 298. VVM - Vaccine Vial Monitor, color chart (inner square darker = discard) 299. Cold chain - ILR (2-8°C), deep freezer (-20°C) 300. RNTCP/NTEP - TB treatment (2HRZE/4HR), DRTB regimen 301. NACP - AIDS program, PPTCT 302. NPCDCS - cancer, diabetes, cardiovascular screening 303. Wilson's criteria - 10 criteria for screening 304. Lead-time bias - apparent survival gain without true benefit 305. PQLI - Physical Quality of Life Index (literacy + IMR + CMR) 306. Nalgonda technique - defluoridation of water 307. Hardness of water - calcium + magnesium, boiling vs ion exchange 308. IMR, CMR, MMR, NMR - formulae and current values 309. Total fertility rate vs GFR - population growth 310. Epidemiological triad - host, agent, environment

TIER 2 - VERY IMPORTANT (311-400)

  1. Goodpasture's syndrome (anti-GBM, pulmonary-renal)
  2. Antineutrophil cytoplasmic antibodies - PR3 vs MPO (ANCA vasculitis)
  3. Wegener's granulomatosis (GPA) - saddle nose, lung cavities
  4. Sjogren's syndrome - dry eyes, anti-Ro/La
  5. Dermatomyositis/polymyositis - heliotrope rash, anti-Jo1
  6. Mixed connective tissue disease (anti-U1RNP)
  7. Myasthenia gravis - AChR antibody, edrophonium test
  8. Lambert-Eaton syndrome - VGCCs, autonomic features
  9. GBS (Guillain-Barre) - ascending paralysis, albuminocytological dissociation
  10. Trigeminal neuralgia - V2>V3, carbamazepine
  11. Motor neuron disease (ALS) - upper + lower MN signs
  12. Huntington's disease - CAG repeat, caudate atrophy
  13. Wilson's disease - copper, Kayser-Fleischer, ceruloplasmin
  14. Hepatic encephalopathy - grading, lactulose
  15. Portal hypertension - esophageal varices, TIPS
  16. Primary biliary cholangitis (AMA, cholestasis)
  17. Primary sclerosing cholangitis - IBD association
  18. Autoimmune hepatitis - anti-smooth muscle Ab
  19. NAFLD/NASH progression
  20. Hepatorenal syndrome - type 1 vs 2
  21. Renal tubular acidosis - types, anion gap
  22. Polycystic kidney disease - ADPKD, berry aneurysm
  23. Nephrolithiasis - calcium oxalate (most common), uric acid (radiolucent)
  24. AKI - KDIGO criteria, prerenal vs intrinsic vs postrenal
  25. CKD - eGFR stages, management
  26. Glomerulonephritis - classification (nephrotic vs nephritic)
  27. Hyponatremia - SIADH, cerebral salt wasting, management
  28. Hyperkalemia - ECG changes, treatment
  29. Hypercalcemia - causes (malignancy, hyperPTH), treatment
  30. COPD - GOLD classification, bronchodilators, inhaler technique
  31. Asthma - GINA steps, salbutamol, ICS
  32. Pulmonary fibrosis - IPF, UIP pattern, pirfenidone
  33. Pleural effusion - Light's criteria, transudate vs exudate
  34. Lung cancer - NSCLC vs SCLC, targeted therapy (EGFR, ALK)
  35. Mesothelioma - asbestos, calretinin marker
  36. Hypertrophic cardiomyopathy - LVOT obstruction, sudden death
  37. Dilated cardiomyopathy - causes, management
  38. Constrictive pericarditis - Kussmaul's sign
  39. Cardiac tamponade - Beck's triad, pulsus paradoxus
  40. Atrial fibrillation - CHA2DS2-VASc, anticoagulation
  41. Wolff-Parkinson-White - delta wave, accessory pathway
  42. Long QT syndrome - torsades de pointes, triggers
  43. Acute mitral regurgitation (papillary muscle rupture post-MI)
  44. Aortic stenosis - carotid pulse (pulsus parvus et tardus), gradient
  45. HOCM vs AS - differentiating maneuvers
  46. Constipation-Megacolon - Hirschsprung vs acquired
  47. Celiac disease - anti-tTG, HLA-DQ2/DQ8, villous atrophy
  48. Whipple's disease - PAS positive macrophages
  49. Malabsorption - D-xylose test, fat globules stool
  50. Peptic ulcer - H. pylori (CLO test, urea breath test)
  51. GERD - complications (Barrett's), PPI use
  52. Zollinger-Ellison syndrome - gastrinoma, MEN-1
  53. Insulinoma - Whipple's triad, C-peptide elevated
  54. Carcinoid tumor - 5-HIAA, serotonin
  55. Pheochromocytoma - rule of 10, VMA, metanephrine
  56. Neuroblastoma - N-MYC, VMA, calcification
  57. Phyllodes tumor of breast
  58. Male breast cancer - BRCA2, risk
  59. Testicular tumors - AFP (YST), beta-hCG, LDH
  60. Prostate cancer - PSA, Gleason score
  61. Renal cell carcinoma - clear cell, VHL, sunitinib
  62. Transitional cell carcinoma - risk factors (schistosomiasis)
  63. Wilms' tumor - WT1 gene, nephroblastoma
  64. Ewing's sarcoma - t(11;22), EWSR1-FLI1
  65. GIST - c-KIT (CD117), imatinib
  66. Melanoma - ABCDE criteria, Breslow thickness
  67. BCC vs SCC - features, treatment
  68. Merkel cell carcinoma
  69. Kaposi sarcoma - HHV-8, AIDS-related
  70. Pilonidal sinus - sacrococcygeal, treatment
  71. Sinus tract vs fistula - definitions
  72. Varicose veins - surgical treatment vs sclerotherapy
  73. Lymphedema - primary vs secondary, treatment
  74. Raynaud's phenomenon - primary vs secondary
  75. Buerger's disease (TAO) - smoking, young males
  76. Takayasu's arteritis - aorta, young females
  77. Temporal arteritis - ESR, ophthalmic artery, biopsy
  78. Polyarteritis nodosa - medium vessels, ANCA negative
  79. Sepsis - qSOFA, Surviving Sepsis Campaign guidelines
  80. Shock - classification, vasopressors (norepinephrine first)
  81. Toxic shock syndrome - Staph vs Strep, toxin
  82. Meningococcemia - Waterhouse-Friderichsen
  83. Leptospirosis - Weil's disease, doxycycline
  84. Brucellosis - rose spots, agglutination tests
  85. Tetanus - opisthotonus, antitoxin
  86. Botulism - descending paralysis, canned food
  87. Diphtheria - pseudomembrane, bull neck
  88. Rabies - Negri bodies, Milwaukee protocol
  89. Q fever - Coxiella, phase II antigen
  90. Rocky Mountain Spotted Fever - R. rickettsii, petechial

TIER 3 - IMPORTANT (401-500)

401-420: Dermatology (Urticaria, Eczema, Acne, Fungal infections, STIs, Vitiligo, Drug reactions, Leprosy classifications, Hair disorders) 421-430: Radiology (X-ray patterns, CT principles, MRI uses, contrast agents, USG Doppler) 431-445: Anaesthesia (MAC values, Isoflurane/Sevoflurane/Desflurane differences, Propofol, Ketamine, Suxamethonium, Vecuronium, Regional blocks, ICU monitoring, Pain ladder) 446-460: Psychiatry additional (OCD, PTSD, anxiety disorders, eating disorders, cognitive tests - MMSE, personality disorders) 461-470: ENT additional (Otitis media, Mastoiditis, Meniere's disease, BPPV, Epistaxis) 471-480: Ophthalmology additional (Uveitis, Scleritis, Episcleritis, Cataract types, Amblyopia) 481-490: Pediatrics additional (Kawasaki, Henoch-Schönlein purpura, JIA, Cystic fibrosis, Celiac in children) 491-500: Miscellaneous high-yield (Fluid resuscitation formulas, Nutritional deficiency images, Drug-induced diseases, Paraneoplastic syndromes, Hormone receptor targets)

QUICK SUMMARY - STRATEGY FOR NEET PG 2026

PriorityAction
Week 1-4Master the Top 50 ranked topics (all appeared every year)
Week 5-8Cover Tier 1 topics 51-200
Week 9-12Tier 2 topics + image-based question practice
Final 2 weeksRapid revision of all clinical one-liners + PYQ solving
Image prepDR fundus, ECG strips, peripheral smear, X-rays, histology
Daily50 MCQs from PYQ bank (Prepladder/Marrow/DBMCI)
Key Insight: ~30% of NEET PG questions are direct or modified repeats from the previous 5 years. Mastering the top 200 topics in this list can realistically account for 70-80% of your score.
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