The DeMeester Score is a composite scoring system developed by DeMeester and Johnson from 24-hour ambulatory pH monitoring. It combines six components:
Number of reflux episodes per day
Number of long reflux episodes (> 5 minutes) per day
Longest reflux episode duration
Total time with pH < 4.0
Upright time with pH < 4.0
Supine time with pH < 4.0
Clinical Significance
A DeMeester score > 14.72 OR total distal esophageal acid exposure time > 5–6% are the commonly used thresholds for pathologic reflux.
The score correlates clinically with GERD severity — it reflects the pattern of reflux and esophageal clearance.
However, according to current guidelines (Lyon Consensus), acid exposure time (AET) is now considered more reliable than the DeMeester Score and is preferred for diagnosis of GERD.
Patients with a normal DeMeester score and normal acid exposure time should not be considered for antireflux surgery.
Sources: Current Surgical Therapy 14e; Mulholland and Greenfield's Surgery, 7e; Sabiston Textbook of Surgery
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