import os, sys, time
from gtts import gTTS

OUT = "/tmp/workspace/htn-audio"
PARTS = os.path.join(OUT, "parts")
os.makedirs(PARTS, exist_ok=True)

SEGMENTS = [
("Intro", """Hi doctor, and welcome to your first day survival audio on hypertension. Today you are not just an intern. You are the plumber of the human body.
Picture the arteries as garden hoses, the heart as the pump, and blood pressure as the water pressure inside the hose. Too much pressure for too many years, and the hoses crack. In the brain, that is a stroke. The pump becomes thick and tired. That is heart failure. The tiny filters in the kidney get clogged. That is kidney disease.
So everything we do today has one goal: protect the brain, the heart and the kidneys. Not just make a number look nice.
This audio is built from the Belarus Ministry of Health protocol you shared, plus a few extra safety tips from me. It is a study aid. Your senior doctor, your hospital rules and the drug leaflet always come first."""),

("Step zero: is the number real?", """Before any pill, make sure the number is real. A wrong number leads to a wrong diagnosis.
Let the patient rest for 5 minutes, seated, back supported, legs uncrossed, no coffee, no smoking for 30 minutes. Use the right cuff size, at heart level. On the first visit, measure both arms and use the arm with the higher reading from then on. Take at least two readings and average them.
Hypertension means office pressure of 140 over 90 or more, confirmed on two visits, one to two weeks apart. There is one shortcut. If the pressure is above 180 over 110 and there are signs of organ damage, one visit is enough.
If the clinic number is high but you suspect white coat hypertension, or the clinic number is normal but you suspect masked hypertension, ask your senior about home readings or 24 hour monitoring."""),

("Meet the team", """Now meet your drug team. Think of a football team.
Three main players start almost every match. We call them A, C and D.
A is the ACE inhibitor or the ARB.
C is the calcium channel blocker.
D is the diuretic, the thiazide type.
Then there is the specialist, the beta blocker, who only plays in special matches.
And on the bench there are substitutes for hard cases: spironolactone, alpha blockers and central drugs.
Let us meet them one by one, with what they do, when to pick them, and when to keep them far away from the patient."""),

("Player A", """Player A. ACE inhibitors, like lisinopril, ramipril, perindopril and enalapril. And their cousins the ARBs, like losartan, valsartan, telmisartan and candesartan.
Imagine angiotensin as a bossy hormone. It squeezes the pipes and tells the kidney to hold on to salt and water. These drugs shut it up. The pipes relax. And as a bonus, they protect the kidney and the heart.
So pick A when your patient has diabetes, especially with protein in the urine. Chronic kidney disease with protein in the urine. Heart failure. A past heart attack. Or a thick left ventricle.
A small tip. ACE inhibitors cause a dry cough in some people. If that happens, switch to an ARB. It works almost the same, without the cough.
Now the contraindications. Use the memory word P, R, A, H.
P is pregnancy, or a woman planning pregnancy. These drugs can harm the baby.
R is renal artery stenosis on both sides. The kidney depends on that angiotensin squeeze to keep filtering, so the kidney can fail.
A is angioedema, swelling of the lips, tongue or throat, mainly with ACE inhibitors.
H is high potassium.
Two golden rules. Never combine an ACE inhibitor with an ARB. It adds harm without adding benefit. And check creatinine and potassium one to two weeks after starting. A small rise in creatinine, up to about 30 percent, is acceptable. More than that, call your senior. Also, if the patient has vomiting or diarrhoea, tell them to pause this pill until they eat and drink normally again. That is called the sick day rule."""),

("Player C", """Player C. Long acting calcium channel blockers, like amlodipine, lercanidipine and long acting nifedipine.
Calcium makes the muscle in the artery wall squeeze. Block the calcium, and the pipe opens wide.
They are friendly drugs. No problem in gout, asthma or diabetes. They work very well in older people and in people with angina.
The classic side effects are ankle swelling, flushing and headache. Here is a tip. The ankle swelling is not heart failure or kidney failure. It is the drug opening small vessels. Adding an ACE inhibitor or ARB reduces it.
Be careful in very low blood pressure and in severe aortic stenosis.
Now a different cousin: verapamil and diltiazem. They also slow the heart. So do not use them in heart failure with a weak pump, in a slow pulse, or in heart block. And do not casually mix them with a beta blocker."""),

("Player D", """Player D. The diuretic. Think of squeezing a sponge. The kidney lets go of salt and water, the volume in the pipes falls, and pressure falls.
The protocol prefers thiazide type drugs: indapamide, chlorthalidone and hydrochlorothiazide. They are great for older people, for people with swelling, and for stroke prevention.
Cautions. Remember G, H, H, H.
G is gout. These drugs raise uric acid.
H is hypokalaemia, low potassium.
H is hyponatraemia, low sodium, especially in older women.
H is hypercalcaemia, high calcium.
They can also nudge blood sugar up a little. So check sodium, potassium and creatinine within a couple of weeks of starting.
In kidney disease, plain hydrochlorothiazide loses power. The protocol suggests switching to chlorthalidone or indapamide, and adding torasemide, a loop diuretic, when there is kidney disease or fluid retention. Also avoid starting diuretics in pregnancy."""),

("The beta blocker", """Now the specialist: the beta blocker, like bisoprolol, carvedilol, metoprolol or nebivolol. Think of it as the brake pedal for the heart. It slows the heart rate and softens each beat.
It is not the usual first choice for plain hypertension. Call it in when the patient has angina, a previous heart attack, heart failure, a fast resting pulse above 80, or atrial fibrillation that needs rate control. Always together with the main drugs.
Contraindications. Remember A, B, C.
A is asthma, or severe bronchospasm.
B is block. Second or third degree heart block.
C is a slow heart, bradycardia.
Also be careful in severe peripheral artery disease. And in diabetic patients on insulin, since a beta blocker can hide the warning shakiness and racing heart of low sugar.
Never stop a beta blocker suddenly. The heart can rebound with angina or a surge in pressure."""),

("The bench", """Now the bench players.
Spironolactone, 25 to 50 milligrams, is the power substitute for resistant hypertension. The danger is high potassium, so check potassium and kidney function. Men may get breast enlargement. Eplerenone is the alternative, but in the protocol it is off label and needs a medical council decision.
Alpha blockers, doxazosin and terazosin, are handy for men with an enlarged prostate. But they can drop the pressure when standing. So give the first dose at bedtime.
Central drugs, moxonidine and clonidine. Clonidine can cause a rebound rise in pressure if stopped suddenly.
And methyldopa. The protocol says: only in pregnancy and breastfeeding."""),

("The ladder", """Now your real tactic: the drug ladder.
Step one. Start with TWO drugs, ideally in one pill. A plus C, or A plus D. Fewer pills means more patients actually take them.
Step two. Still above 140 over 90? Go to THREE: A plus C plus D, ideally in one pill.
Step three. Still high? Think resistant hypertension, meaning high pressure despite three drugs at good doses including a diuretic. Before you add anything, ask five questions. Is the patient really taking the pills? Is the measurement technique right? Are other drugs raising the pressure, like painkillers called NSAIDs, steroids, contraceptive pills or decongestants? Is there too much salt or alcohol? Could it be sleep apnoea or a hormonal cause? Then maximise the triple, switch to chlorthalidone or indapamide, add spironolactone, and only then think about beta blockers, alpha blockers or central drugs.
When is one drug enough? In low risk grade one hypertension with pressure under 150 over 95, in people aged 80 or more, and in frail older people.
Good pairs: ACE inhibitor with a calcium channel blocker, or ACE inhibitor with a diuretic.
Bad pair: ACE inhibitor with an ARB.
Think twice about: a beta blocker with verapamil or diltiazem, because the heart may slow too much. A beta blocker with a thiazide in a prediabetic patient, because both nudge sugar up. And the triple whammy: ACE inhibitor or ARB, plus a diuretic, plus an NSAID painkiller. This can wreck the kidneys. Always ask about painkillers."""),

("Situations, rapid fire", """Rapid fire. Which drugs in which situation?
Diabetes with protein in the urine: A first, then add C or D.
Chronic kidney disease: A plus a diuretic, and watch potassium and creatinine.
Heart failure with a weak pump: A, a beta blocker and spironolactone. Avoid verapamil and diltiazem.
Angina or after a heart attack: A plus a beta blocker, and add amlodipine if needed.
Older patient: C or D with A. Start low, go slow, and check standing pressure. If the pressure falls 20 points systolic or 10 diastolic within 3 minutes of standing, that is postural hypotension, and it means falls and fractures.
Gout: avoid thiazides. Use A plus C.
Asthma: avoid beta blockers.
Man with a big prostate: an alpha blocker can be added.
Pregnancy: no ACE inhibitor, no ARB. The protocol allows methyldopa, and from my side, long acting nifedipine and labetalol are commonly used. The Goldman Cecil textbook says that in pregnancy, pressure at or above 160 over 110 needs immediate treatment.
Black African patients, from my side: calcium channel blockers and thiazides usually work better as a first drug, and ACE inhibitor angioedema is more common.
Woman who could become pregnant: think twice before ACE inhibitors and ARBs, and talk about contraception."""),

("Targets and follow up", """Targets. Step one: under 140 over 90. If the patient tolerates it, go to 130 over 80 or lower. But never below 120 over 70. Lower is not always better.
Lifestyle is for every patient at every grade. Salt under 5 grams a day. Stop smoking. Alcohol as little as possible. Exercise 150 minutes a week. Aim for a healthy weight. Lots of vegetables and fruit.
Beyond pressure: statins for cholesterol. Low dose aspirin only if the patient already has atherosclerotic disease, like a heart attack, an ischaemic stroke or peripheral artery disease. The protocol says do not give aspirin for primary prevention.
The protocol's first review is 3 months after starting treatment. From my side, in real practice your senior may want a check of potassium and creatinine, and a pressure check, within 2 to 4 weeks, especially after starting ACE inhibitors, ARBs or diuretics."""),

("Hypertensive crisis", """Now the scary part. Hypertensive crisis. Stay calm. One single question rules everything: is any organ being damaged right now?
Imagine the pipes are leaking. Where? Brain: confusion, severe headache with vomiting, seizure, weakness, speech or vision change. Heart: chest pain. Lungs: breathlessness, fluid in the lungs. Aorta: tearing pain in the chest or back, with different pressures in the two arms. Kidney: sudden fall in urine and new kidney failure. Pregnancy: high pressure with protein in urine, headache or seizures. That is eclampsia.
If YES, it is a COMPLICATED crisis. This is an emergency. Call for help, hospitalise urgently, IV drugs, monitoring.
If NO, it is an UNCOMPLICATED crisis. The pressure is high, the patient has symptoms like headache or palpitations, but no acute organ damage. You can treat it in the outpatient clinic. The rule: lower gradually. No more than 25 percent in the first 2 hours, then to the normal range within 24 hours. Why not faster? Because the brain and heart have adapted to high pressure. Drop it too fast, and they get starved of blood.
The protocol says: choose ONE drug. Captopril 25 to 50 milligrams by mouth or under the tongue. Or nifedipine 10 milligrams by mouth. Or propranolol 40 milligrams. Or glyceryl trinitrate 0.5 milligrams under the tongue. Or furosemide 20 to 60 milligrams IV, or urapidil IV given slowly under pressure control. If these fail, moxonidine or clonidine by mouth.
A safety note from my side. Many international guidelines discourage short acting nifedipine, especially under the tongue, because the fall can be sudden and unpredictable. Ask your senior which drug your hospital prefers before you give anything.
Another tip from me. A high number in a calm patient with no symptoms is not an emergency. Check the cuff, let the patient rest, repeat the measurement, ask if they missed their pills, restart or intensify treatment, and arrange a follow up in a few days. Do not rush to bring it down.
Send the patient to hospital if the crisis is complicated, or if it is uncomplicated but symptoms worsen and cannot be reversed in the clinic."""),

("Emergency targets", """In the hospital, the targets depend on which organ is in trouble. Learn them like a story.
Heart attack or fluid in the lungs: bring systolic pressure quickly under 140. Nitrates and furosemide are friends here.
Aortic dissection, the most aggressive: systolic under 120 and heart rate under 60. Control the heart rate first.
Hypertensive encephalopathy, and malignant hypertension with kidney failure: lower the mean pressure by only 20 to 25 percent over several hours. The mean pressure is systolic minus diastolic, divided by 3, plus the diastolic. Example: 200 over 120. 200 minus 120 is 80. Divide by 3 is about 27. Add 120, and the mean is about 147. A 20 to 25 percent fall means a target of about 110 to 117.
Now the twist. Ischaemic stroke: do the opposite. Do NOT lower pressure unless it is above 220 over 120 in the first 24 hours. If thrombolysis is given, keep it under 180 over 105.
Brain bleed: within 6 hours, lower to about 140 over 90, but not more than 60 points of systolic in total. After 6 hours, if systolic is above 220, lower slowly to under 180 over several hours.
Two extra warnings from me. If you suspect phaeochromocytoma, the hormone tumour, a beta blocker alone can make things worse, so ask a senior. And in eclampsia, the key drug is IV magnesium sulfate, with a safe antihypertensive."""),

("Your checklist", """Let us close with your tactic cheat sheet.
One. Measure correctly, both arms on the first visit.
Two. Confirm with two visits, or home or 24 hour monitoring when in doubt.
Three. Grade the hypertension, check risk factors and organ damage, and write the diagnosis.
Four. Start with two drugs, A plus C or A plus D, in one pill. Move to three if needed.
Five. Beta blockers are for special situations: angina, heart attack, heart failure, fast pulse.
Six. Memory words. P, R, A, H for ACE inhibitors and ARBs. G, H, H, H for diuretics. A, B, C for beta blockers.
Seven. In a crisis, ask: is an organ being damaged right now? Yes means hospital. No means lower slowly, no more than 25 percent in 2 hours.
Eight. Before the patient leaves, give lifestyle advice with numbers, explain the pills and side effects, teach home measurement, set the next visit, and explain danger signs: severe headache, chest pain, breathlessness, weakness, speech or vision change. Those mean come to emergency.
Remember, this is a study aid. Always check with your senior doctor, your hospital protocol and the drug leaflet before prescribing. You are going to be great. Good luck on your shift, doctor!"""),
]

# transcript
with open(os.path.join(OUT, "transcript.md"), "w") as f:
    f.write("# Hypertension survival audio: transcript\n\n")
    for t, s in SEGMENTS:
        f.write(f"## {t}\n\n{s}\n\n")

def synth(i, text):
    path = os.path.join(PARTS, f"p{i:02d}.mp3")
    if os.path.exists(path) and os.path.getsize(path) > 1000:
        return path
    for attempt in range(4):
        try:
            gTTS(text.replace("\n", " "), lang="en", tld="com").save(path)
            return path
        except Exception as e:
            print("retry", i, e, flush=True)
            time.sleep(3)
    raise RuntimeError("failed " + str(i))

paths = []
for i, (t, s) in enumerate(SEGMENTS):
    print("synth", i, t, flush=True)
    paths.append(synth(i, s))

final = os.path.join(OUT, "Hypertension_Survival_Audio_for_Interns.mp3")
with open(final, "wb") as out:
    for p in paths:
        out.write(open(p, "rb").read())
print("DONE", os.path.getsize(final), flush=True)