Syp albendazolde stat dose 2 year male 9.8 kg
Reading File
Searching the Web
albendazole syrup dose 2 year child 400mg WHO deworming
Finding Sources
Here is the confirmed dosing information:
Albendazole Syrup - Stat Dose
Patient: 2-year-old male, 9.8 kg
| Parameter | Detail |
|---|---|
| Drug | Albendazole suspension (syrup) |
| Concentration | 200 mg / 5 mL |
| Dose | 400 mg (single stat dose) |
| Volume | 10 mL |
| Route | Oral, with or after food |
| Frequency | Single dose (stat) |
Age-based Dosing Logic
- < 12 months: Not recommended routinely
- 12-23 months (under 2 years): 200 mg (half dose per WHO)
- ≥ 2 years: 400 mg - full single dose
This child is exactly 2 years old, so the full 400 mg dose applies.
Weight Check
At 9.8 kg, some references (e.g., BNF/BNFC) use weight-based dosing:
- If using <10 kg cutoff: some sources give 200 mg (half dose) for children under 10 kg regardless of age.
- Per WHO MDA (Mass Drug Administration) guidelines: age ≥ 2 years = 400 mg, regardless of weight.
Clinical note: Given the child is borderline (9.8 kg, just under 10 kg), it is prudent to check local protocol. If following WHO deworming guidelines, give 400 mg (10 mL). If following a weight-based protocol (<10 kg = 200 mg), give 200 mg (5 mL). Most standard Indian pediatric practice follows the age-based WHO approach and gives 400 mg for a 2-year-old.
- Goodman & Gilman's Pharmacological Basis of Therapeutics confirms: "400 mg single oral dose for children greater than 2 years"
- Katzung's Basic and Clinical Pharmacology, 16th Ed. confirms: "adults and children older than 2 years... single dose of 400 mg orally"
Bottom line: Give 400 mg = 10 mL of Albendazole 200 mg/5 mL syrup as a single oral stat dose, ideally with food.
Cefriaxone dose iv
Finding Sources
Reading File
Reading File
Here is a complete, indication-based ceftriaxone IV dosing reference:
Ceftriaxone IV Dosing
Children (by indication)
| Indication | Dose | Frequency | Max |
|---|---|---|---|
| General infections (pneumonia, UTI, skin) | 50 mg/kg/day | Once daily | 2 g/day |
| Severe/serious infections | 80-100 mg/kg/day | Once daily or ÷ q12h | 4 g/day |
| Bacterial meningitis | 100 mg/kg/day | q12h (÷ in 2 doses) | 4 g/day |
| Meningococcal meningitis | 50 mg/kg | q12h | - |
| Typhoid fever | 60-80 mg/kg/day | Once daily | 2-3 g/day |
| Neonates (<28 days) | ⚠️ Avoid | - | - |
⚠️ Neonates (<3 months / <28 days): Ceftriaxone is contraindicated in hyperbilirubinemic neonates and those requiring calcium-containing IV fluids (risk of fatal ceftriaxone-calcium precipitates). Use cefotaxime instead (50 mg/kg q6-8h).
Adults
| Indication | Dose | Frequency |
|---|---|---|
| Mild-moderate infections | 1 g IV | Once daily |
| Severe infections / sepsis | 2 g IV | Once daily or q12h |
| Bacterial meningitis | 2 g IV | q12h |
| Meningococcal meningitis | 1-2 g IV | q12h |
| Surgical prophylaxis | 1-2 g IV | Single pre-op dose |
| Gonorrhoea (uncomplicated) | 250-500 mg IM/IV | Single dose |
| Endocarditis | 2 g IV | Once daily (4 weeks) |
Administration
| Detail | |
|---|---|
| IV infusion | Dilute in NS or D5W, infuse over 30 minutes |
| IV bolus | Can give over 5 min (≥250 mg/mL concentration) |
| IM | Dilute with 1% lidocaine to reduce pain |
| Do NOT | Mix with calcium-containing fluids (Ringer's, Hartmann's) |
For your patient (2-yr, 9.8 kg)
| Indication | Calculated Dose | Volume (250 mg/mL vial) |
|---|---|---|
| General infection | 50 mg/kg = ~490 mg → give 500 mg OD | 2 mL |
| Serious infection | 80 mg/kg = ~784 mg → give 750 mg-800 mg OD | 3 mL |
| Meningitis | 100 mg/kg = ~980 mg → give 1 g q12h | 4 mL per dose |
Zinc syrup dose
Finding Sources
Searching the Web
zinc syrup dose children WHO recommendation diarrhea supplementation mg/day
Here is the complete zinc syrup dosing reference:
Zinc Syrup Dosing (Elemental Zinc)
1. Acute Diarrhea Treatment (WHO/UNICEF Standard)
| Age | Dose | Duration |
|---|---|---|
| < 6 months | 10 mg/day | 10-14 days |
| 6 months - 5 years | 20 mg/day | 10-14 days |
| > 5 years / adults | 40 mg/day | 10-14 days |
Given alongside ORS (oral rehydration solution) - the two-pronged WHO approach to acute diarrhea management.
Effect: Reduces duration of diarrhea, decreases stool output, prevents recurrence for up to 2-3 months after the course.
2. Common Zinc Syrup Formulations
| Formulation | Concentration |
|---|---|
| Zinc sulfate syrup | 10 mg elemental zinc / 5 mL |
| Zinc gluconate syrup | 10 mg elemental zinc / 5 mL |
| Zinc acetate dispersible tablet | 20 mg (can dissolve in 5 mL water) |
3. Dose in mL by Age
| Age | Dose | Volume (10 mg/5 mL syrup) |
|---|---|---|
| < 6 months | 10 mg/day | 5 mL once daily |
| 6 months - 5 years | 20 mg/day | 10 mL once daily |
4. For your patient (2-yr, 9.8 kg)
20 mg elemental zinc once daily x 10-14 days = 10 mL of zinc syrup (10 mg/5 mL) once daily with food
5. Nutritional Supplementation (non-diarrhea)
| Age | RDA (Elemental Zinc) |
|---|---|
| 0-6 months | 2 mg/day |
| 7-12 months | 3 mg/day |
| 1-3 years | 3 mg/day |
| 4-8 years | 5 mg/day |
| 9-13 years | 8 mg/day |
Key Points
- Give zinc with food or after food to reduce nausea/vomiting
- Do not exceed 20 mg/day in young children (higher doses increase vomiting risk)
- A recent NEJM trial showed 5-10 mg/day had similar efficacy to 20 mg with less vomiting - lower doses may be considered if vomiting is a concern
- Prolonged use (>2 weeks) can cause copper deficiency - per Goldman-Cecil Medicine
- Always combine with ORS in diarrhea management
Iv metrogyl
Finding Sources
Searching the Web
IV metronidazole metrogyl dose children adults mg/kg infusion
Here is the complete IV Metronidazole (Metrogyl) dosing reference:
IV Metronidazole (Metrogyl) Dosing
Formulation
500 mg / 100 mL (5 mg/mL) ready-to-use IV infusion bag
Children
| Age | Dose | Frequency | Max/day |
|---|---|---|---|
| < 8 weeks (neonates) | 7.5 mg/kg | q12h (once daily if premature) | 15 mg/kg/day |
| 8 weeks - 12 years | 7.5 mg/kg/dose | q8h | 40 mg/kg/day |
| > 12 years | Adult dose | - | 4 g/day |
Surgical prophylaxis (children <12 yrs): 20-30 mg/kg as single dose, 1-2 hours before surgery.
Adults
| Regimen | Dose | Notes |
|---|---|---|
| Loading dose | 15 mg/kg IV (~1 g) | Infuse over 1 hour |
| Maintenance dose | 7.5 mg/kg IV (~500 mg) | Every 6-8 hours |
| Standard simplified | 500 mg IV | q8h (most common in practice) |
| Max dose | 4 g/24 hours | Do not exceed |
| Duration | 7-10 days | Bone/joint/endocarditis may need longer |
Surgical prophylaxis (adults): 1000-1500 mg IV single dose 30-60 min pre-op, then 500 mg q8h.
For your patient (2-yr, 9.8 kg)
7.5 mg/kg/dose = ~73 mg per dose → Give 75 mg IV every 8 hours → From 500 mg/100 mL vial = 15 mL per dose, infuse over 30 minutes
Indication-based Dosing
| Indication | Dose | Duration |
|---|---|---|
| Anaerobic infections / sepsis | 7.5 mg/kg q8h | 7-10 days |
| Intra-abdominal infections | 7.5 mg/kg q8h | 5-7 days |
| C. difficile (adults) | 500 mg q8h PO (IV if severe) | 10-14 days |
| Amoebic liver abscess | 7.5 mg/kg q8h | 5-10 days |
| Surgical prophylaxis | 15 mg/kg single dose | Pre-op only |
Administration
| Parameter | Detail |
|---|---|
| Rate | Infuse over 30-60 minutes (never bolus) |
| Diluent | Pre-diluted (5 mg/mL); can use NS or D5W |
| Protect from light | Yes |
| Compatibility | Do NOT mix with other drugs in same line |
Dose Adjustments
| Condition | Adjustment |
|---|---|
| Severe hepatic impairment | Reduce by 50% |
| Renal impairment | No adjustment needed for standard courses |
| Hemodialysis | Supplement dose after session (metronidazole is dialyzable) |
- Source: FDA prescribing information, UK SmPC (emc)
This is a shared conversation. Sign in to Orris to start your own chat.