Reversible causes for cardiac arrest mnemonic

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reversible causes cardiac arrest mnemonic 4H 4T

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The classic mnemonic for reversible causes of cardiac arrest is the 4 Hs and 4 Ts (sometimes called 5 Hs and 5 Ts in expanded versions). These are particularly important when managing PEA (pulseless electrical activity) and asystole.

The 4 Hs and 4 Ts (AHA / Resuscitation Council)

🅷 The 4 Hs

HCauseKey Action
HypoxiaMost common non-cardiac cause of arrestEnsure airway, high-flow O₂, ventilation
HypovolemiaHemorrhage, dehydration, distributive shockIV fluids, blood products, stop bleeding
Hypo/Hyperkalemia (+ other electrolytes/metabolic)K⁺ imbalance, acidosis (H⁺ ions), Ca²⁺ disorders12-lead ECG, electrolytes, correct metabolic derangement
HypothermiaCore temp <30°C can cause refractory VFActive rewarming ("not dead until warm and dead")

🅣 The 4 Ts

TCauseKey Action
Tension pneumothoraxTracheal deviation, absent breath sounds, raised JVPNeedle decompression → chest drain
Tamponade (cardiac)Beck's triad, muffled heart sounds, raised JVPPericardiocentesis
ToxinsDrug overdose (digoxin, β-blockers, CCBs, TCAs), poisoningAntidotes, activated charcoal, supportive care
ThrombosisPulmonary embolism or coronary thrombosis (MI)Thrombolytics / PPCI / surgical embolectomy

Expanded Version: 5 Hs and 5 Ts

Some sources (including Miller's Anesthesia and the AHA algorithm) split thrombosis and/or electrolytes further:
ExtraCause
Hydrogen ions (acidosis)Counted separately from electrolytes
Thrombosis – PulmonaryPE
Thrombosis – CoronaryACS/MI

Quick Memory Aid

"Hot Docs Give Help" (less common) or simply remember:
4 Hs: Hypoxia · Hypovolemia · Hypo/Hyperkalemia (+ H⁺ acidosis) · Hypothermia
4 Ts: Tension pneumo · Tamponade · Toxins · Thrombosis
These causes matter most in PEA and asystole — the non-shockable rhythms where identifying and correcting the underlying etiology is the primary treatment strategy, since no electrical shock is effective. VF/pulseless VT should also have these causes considered if refractory to defibrillation.
(Miller's Anesthesia, 10e — Pulseless Electrical Activity section; Goldman-Cecil Medicine — Asystole, Bradyarrhythmias, and PEA section)
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