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The Brachial Plexus - A Complete, Unforgettable Guide

The Big Picture First

The brachial plexus is the nerve network supplying the entire upper limb. Five spinal nerve roots enter, get reorganized through a series of junctions, and exit as five major terminal nerves. Think of it like a train-line interchange where passengers (nerve fibers) change platforms before reaching their final destination.
The 5-level hierarchy (mnemonic: "Read That Damn Cold Beer"):
LevelNameNotes
R - RootsC5, C6, C7, C8, T1Anterior rami between scalene muscles
T - TrunksSuperior, Middle, Inferior3 trunks over rib I
D - DivisionsAnterior + Posterior6 divisions - NO nerves branch here
C - CordsLateral, Posterior, MedialNamed by position relative to axillary artery
B - Branches5 terminal + collateral nervesThe final nerves to the arm

LEVEL 1: Roots (C5-T1)

The anterior rami of five spinal nerves emerge between the anterior and middle scalene muscles.
  • Receives gray rami communicantes from the sympathetic trunk (postganglionic sympathetic fibers)
  • Roots already give off two important nerves directly:
    • Dorsal scapular nerve (C5) - rhomboids
    • Long thoracic nerve (C5, C6, C7) - serratus anterior
Brachial plexus in the neck showing roots, trunks, divisions and cords with relation to scalene muscles and sympathetic ganglia

LEVEL 2: Trunks (3 trunks)

The roots merge to form three trunks that cross the base of the posterior triangle over rib I.
TrunkFormed byMemory hook
Superior (upper)C5 + C6"5 and 6 go up together"
MiddleC7 alone"C7 stands alone in the middle"
Inferior (lower)C8 + T1"8 and T1 go down together"
Branches from trunks:
  • Suprascapular nerve (superior trunk, C5-C6) - supraspinatus + infraspinatus
  • Nerve to subclavius (superior trunk, C5-C6) - subclavius muscle

LEVEL 3: Divisions (6 divisions - the "silent" level)

Each trunk splits into an anterior and a posterior division = 6 divisions total.
  • Anterior divisions = future supply for flexor/anterior compartments
  • Posterior divisions = future supply for extensor/posterior compartments
  • No peripheral nerves originate directly from the divisions (this is the one "silent" level)
Schematic diagram showing how C5-T1 roots form Superior/Middle/Inferior trunks, which divide into Anterior/Posterior divisions, then form Lateral/Posterior/Medial cords and terminal nerves

LEVEL 4: Cords (3 cords)

Three cords form from the divisions and are positioned around the 2nd part of the axillary artery (named by their position relative to it).
CordFormed fromRootsPosition
LateralAnterior divisions of Superior + Middle trunksC5, C6, C7Lateral to axillary artery
PosteriorALL THREE posterior divisionsC5-T1Posterior to axillary artery
MedialAnterior division of Inferior trunkC8, T1Medial to axillary artery
Memory trick: "Lateral and Medial cords carry ANTERIOR (flexor) fibers. Posterior cord carries ALL POSTERIOR (extensor) fibers."

LEVEL 5: Branches (Terminal Nerves)

The cords give rise to the major terminal nerves:
Full brachial plexus schematic (A) showing all branches, and (B) anatomical view showing relationships to the axillary artery and all collateral nerves

From the Lateral Cord (C5-C7):

  • Lateral pectoral nerve - pectoralis major (and minor via communication)
  • Musculocutaneous nerve - anterior arm muscles (biceps, brachialis, coracobrachialis) + sensory to lateral forearm
  • Lateral root of median nerve (joins medial root to form the median nerve)

From the Medial Cord (C8-T1):

  • Medial pectoral nerve - pectoralis major + minor
  • Medial cutaneous nerve of arm - sensory medial arm
  • Medial cutaneous nerve of forearm - sensory medial forearm
  • Ulnar nerve - intrinsic hand muscles, medial 1.5 fingers
  • Medial root of median nerve (joins lateral root)

From the Posterior Cord (C5-T1):

  • Upper subscapular nerve - subscapularis
  • Thoracodorsal nerve (C6-C8) - latissimus dorsi
  • Lower subscapular nerve - subscapularis + teres major
  • Axillary nerve (C5-C6) - deltoid + teres minor, sensory lateral arm
  • Radial nerve (C5-T1) - all posterior compartment muscles of arm + forearm

The Median Nerve (special case):

Formed by contributions from BOTH the lateral cord (C5-C7) and medial cord (C8-T1). The two roots unite in a distinctive "M" or "V" shape on the front of the axillary artery. Mnemonic: the Median nerve takes an M-shaped path.

Full Branch Table (Grouped by Origin)

OriginNerveSpinal LevelTarget
C5 rootDorsal scapularC5Rhomboids
C5-C7 rootsLong thoracicC5-C7Serratus anterior
Superior trunkSuprascapularC5-C6Supraspinatus, infraspinatus
Superior trunkNerve to subclaviusC5-C6Subclavius
Lateral cordLateral pectoralC5-C7Pec major/minor
Lateral cordMusculocutaneousC5-C7Anterior arm + lateral forearm skin
Lateral + MedialMedian nerveC5-T1Anterior forearm, lateral palm, radial 3.5 fingers
Medial cordMedial pectoralC8-T1Pec major/minor
Medial cordMed. cutaneous (arm)C8-T1Medial arm skin
Medial cordMed. cutaneous (forearm)C8-T1Medial forearm skin
Medial cordUlnar nerveC8-T1Intrinsic hand, medial 1.5 fingers
Posterior cordUpper subscapularC5-C6Subscapularis
Posterior cordThoracodorsalC6-C8Latissimus dorsi
Posterior cordLower subscapularC5-C6Subscapularis + teres major
Posterior cordAxillary nerveC5-C6Deltoid, teres minor
Posterior cordRadial nerveC5-T1All posterior compartments

Clinical Lesions - The "Exam Favorites"

Erb-Duchenne Palsy (Upper Plexus, C5-C6)

Mechanism: Forceful widening of the angle between head and shoulder - motorcycle accident, shoulder dystocia during birth delivery.
Muscles lost: Deltoid, biceps, brachialis, brachioradialis, supraspinatus, infraspinatus
Classic posture: "Waiter's tip" or "Policeman taking a tip" - arm hangs at side, internally rotated, elbow extended, forearm pronated, wrist flexed.
Sensory loss: Lateral arm + upper lateral forearm

Klumpke's Palsy (Lower Plexus, C8-T1)

Mechanism: Forceful hyperabduction of the arm - catching a branch when falling, difficult breech delivery with arms above head.
Muscles lost: Intrinsic hand muscles (all those small thenar, hypothenar, interossei muscles).
Classic posture: "Claw hand" - hyperextended MCP joints, flexed IP joints (combined median + ulnar intrinsic hand paralysis).
Sensory loss: Medial forearm, hand, medial 1.5 fingers (C8-T1 distribution).
Important: Often associated with Horner's syndrome (ptosis, miosis, anhidrosis, enophthalmos) because T1 fibers also carry sympathetic fibers to the face. Horner's = avulsion injury (worst prognosis).

Other Clinically Important Lesions

NerveCommon injuryKey deficit
Long thoracic (C5-C7)Stab to neck, radical mastectomyWinged scapula (serratus anterior loss)
Axillary (C5-C6)Anterior shoulder dislocation, surgical neck of humerus fractureDeltoid paralysis (can't abduct >15°), patch of sensory loss over "regimental badge" area
Radial (C5-T1)Midshaft humerus fracture ("spiral groove")Wrist drop
MusculocutaneousRare; coracobrachialis entrapmentWeak flexion at elbow, lateral forearm sensory loss

The One Memory Framework That Ties It All Together

ROOTS:   C5 + C6 → SUPERIOR trunk
         C7      → MIDDLE trunk
         C8 + T1 → INFERIOR trunk
                      ↓  (each splits anterior + posterior)
CORDS:   Ant(Superior) + Ant(Middle)     = LATERAL cord  (C5-C7)
         Post(all three)                 = POSTERIOR cord (C5-T1)
         Ant(Inferior)                   = MEDIAL cord   (C8-T1)
                      ↓
TERMINAL: Lateral → Musculocutaneous + (half of) Median
          Posterior → Axillary + Radial
          Medial → Ulnar + (half of) Median
The Median nerve is the "bridge" child - it has parents from both the Lateral AND Medial cords.
The Posterior cord is the largest - it drains ALL three posterior divisions from all 5 roots, which is why the radial nerve (its main branch) has the widest distribution of any upper limb nerve.

Sources: Gray's Anatomy for Students (Elsevier), S. Das Manual on Clinical Surgery 13th Ed., Bradley and Daroff's Neurology in Clinical Practice
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