H Hi, I'm an medical officer, uh, from government, RIMS, Adilabad. I have some doubts like, uh, I have done internship in a very unpractical, I didn't have any practice on the patients. So, in my, uh, casualty, they are coming patients like, uh, they are having high diabetes and high hypertension. Uh, what fluid of choice I should give? And another patients are coming who's, uh, who's having, uh, dizziness or only giddiness. So, what test I should see first and what is the treatment I should do initial? And there are many RTA cases. When they come, uh, what the initial fluid of choice I should try it or what I should do? Please help me.
From Mulholland & Greenfield's Surgery (7e): "Balanced crystalloid solutions (e.g., lactated Ringer's and Plasmalyte) have been associated with a reduced risk of acute kidney injury in critically ill patients."
| Situation | Fluid |
|---|---|
| Hyperglycemia + dehydration (dry tongue, sunken eyes, low urine output) | RL 500 mL over 1-2 hours, reassess |
| Hypertensive urgency (BP very high, patient symptomatic) | Restrict IV fluids - focus on oral antihypertensives first (amlodipine, telmisartan). IV fluids only if truly dehydrated |
| DKA (fruity breath, deep breathing, very high sugar, vomiting) | 0.9% Normal Saline first (1L in 1st hour), then switch to RL. No dextrose initially |
| HHS (Hyperosmolar hyperglycemic state - elderly, very high sugar, no ketones) | 0.9% NS aggressively, then 0.45% NS |

From Washington Manual of Medical Therapeutics: "IV blood product and crystalloid are used for resuscitation of hemorrhagic and fluid depletion shock, respectively, with goal MAP of 60-65 mmHg. Overresuscitation may be detrimental in hemorrhagic shock."
From Mulholland's Surgery (7e): "Current evidence indicates that rather than crystalloids, blood loss in trauma needs to be resuscitated with pRBC and component products. A ratio of 1:1:1 pRBC:FFP:Platelets is the preferred mode."
| Situation | Fluid Choice |
|---|---|
| Mild blood loss, stable BP, talking | RL 1L over 30 min, monitor |
| Moderate blood loss (BP 90-100 systolic, tachycardia) | RL or NS - 1-2L bolus rapidly. Arrange blood |
| Severe shock (BP <90, pale, cold, altered consciousness) | Blood transfusion urgently (Group O negative if crossmatch unavailable). RL as bridging fluid only |
| Isolated head injury (no hypotension) | Normal Saline preferred (avoid RL - hypo-osmolar, can worsen brain edema) |
| Scenario | Fluid of Choice | Key Action |
|---|---|---|
| DM + HTN (dehydrated) | Ringer's Lactate | Avoid dextrose, monitor RBS |
| DKA | 0.9% Normal Saline initially | Insulin protocol, K+ monitoring |
| Dizziness - BPPV | No IV fluid needed | Epley maneuver |
| Dizziness - orthostatic | RL or NS 500mL bolus | Check medications |
| Dizziness - stroke (red flags) | NS (if needed) | CT, aspirin, refer neurology |
| RTA - mild/moderate shock | Ringer's Lactate (1-2L) | Control bleeding, arrange blood |
| RTA - severe shock | Blood (RL as bridge) | 1:1:1 ratio transfusion |
| RTA - head injury | Normal Saline | Avoid RL (osmolarity concern) |
Giddiness??
| Question | Answer | What it suggests |
|---|---|---|
| Does the room spin around you? | Yes | True vertigo - inner ear or brain |
| Do you feel like you'll faint/black out? | Yes | Pre-syncope - cardiac, hypotension, anemia |
| Do you feel unsteady while walking? | Yes | Disequilibrium - cerebellar, Parkinson's, elderly |
| Feature | What you see |
|---|---|
| Onset | With head movement (rolling in bed, looking up) |
| Duration | Seconds to minutes (BPPV) or days (neuritis) |
| Nystagmus | Horizontal, one direction, stops after 30-40 sec, fatigable |
| Hearing | May have hearing loss or tinnitus |
| Walking | Can walk (unsteadily but manages) |
| Neurological signs | NONE |
| Dix-Hallpike test | POSITIVE (vertigo + nystagmus triggered) |
| Feature | What you see |
|---|---|
| Onset | Sudden, spontaneous, not always with movement |
| Duration | Persistent, hours to days |
| Nystagmus | Vertical or multidirectional, does NOT fatigue |
| Hearing | Usually normal |
| Walking | Cannot walk - falls to one side, ataxic |
| Neurological signs | Facial droop, slurred speech, diplopia, limb weakness |
| Dix-Hallpike test | Negative or abnormal pattern |
| Head Impulse Test (HIT) | NEGATIVE (this means DANGEROUS - refer immediately) |
"5% of ED dizziness cases are strokes - and they can present with only dizziness, no other obvious symptoms." - Rosen's Emergency Medicine
| Drug | Dose | Use For | Note |
|---|---|---|---|
| Betahistine (Vertin) | 8-16mg TDS | Vestibular neuritis, Meniere's | Safe, minimal side effects |
| Meclizine (Antivert) | 25mg TDS | Acute vestibular suppression | Onset 1 hour |
| Ondansetron (Zofran) | 4mg IV/oral | Vomiting with vertigo | Good for nausea control |
| Prednisolone | 1mg/kg/day x 5 days | Vestibular neuritis | Speeds recovery |
| Diazepam | 2-5mg oral | Only for severe acute vertigo | Do NOT send home on this - interferes with vestibular compensation |
| Dextrose 50% | 25mL IV bolus | Hypoglycemia | Always rule out first |
Important: Do NOT give benzodiazepines (diazepam) routinely for vertigo and send the patient home - Rosen's specifically warns this interferes with long-term vestibular recovery. Use it only in-hospital for acute severe episodes.
Patient comes with GIDDINESS
|
Check RBS first
BP lying/standing
|
┌──────┴──────┐
Low RBS Normal RBS
(<70)
| |
Give D50 Is it triggered by
IV bolus head movement?
|
┌──────┴──────┐
YES NO
| |
Dix-Hallpike Any red flags?
(HINTS exam) (can't walk, focal
| neuro, severe HA)
Positive? |
| ┌────┴────┐
YES YES NO
| | |
BPPV - do CT head Orthostatic?
Epley maneuver + Refer Vestibular
neurology neuritis?
Treat accordingly
Create a laminated quick reference card for HINTS exam for your casualty
A professional medical laminated quick reference card for the HINTS exam (Head Impulse test, Nystagmus, Test of Skew) for emergency casualty use. The card has a clean clinical design with a bold header "HINTS EXAM" and subtitle "Bedside Test: Peripheral vs Central Vertigo". Three main sections clearly separated with colored blocks: Section 1 - "H: Head Impulse Test" with a simple diagram showing head turn and eye movement, two outcomes: POSITIVE (corrective saccade = PERIPHERAL = SAFE, shown in green) and NEGATIVE (eyes drift = CENTRAL = DANGER, shown in red) Section 2 - "I: Nystagmus Direction" with eye diagrams: Unidirectional (one way only = PERIPHERAL = green) vs Direction-changing (changes with gaze = CENTRAL = red) Section 3 - "T: Test of Skew (Cover-Uncover)" with eye diagrams: No vertical movement = PERIPHERAL (green) vs Vertical deviation on uncover = CENTRAL (red) Bottom section in bold red box: "ANY ONE CENTRAL SIGN = CENTRAL STROKE UNTIL PROVEN OTHERWISE → CT Brain + Neurology Referral" Bottom footer: "HINTS has higher sensitivity than CT for posterior circulation stroke in first 24-48 hours" Color scheme: Navy blue header, white background, green for safe/peripheral, red for danger/central. Clean sans-serif medical font. Designed to be printed on A5 card and laminated for wall display in emergency department.
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Qt
Create a laminated quick reference card for HINTS exam for your casualty
mkdir -p /home/daytona/workspace/hints-card && echo "Directory ready"
~/hints-card/HINTS_Exam_Card.html
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/* ── EYE DIAGRAMS ── */
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/* ── RED ALERT BOX ── */
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</head>
<body>
<div class="card">
<!-- HEADER -->
<div class="header">
<div class="header-left">
<div class="header-title">HINTS</div>
<div class="header-sub">Head Impulse · Nystagmus · Test of Skew</div>
</div>
<div class="header-badge">
USE WHEN PATIENT HAS<br>
<span>CONSTANT VERTIGO</span><br>
(Acute Vestibular Syndrome)
</div>
</div>
<!-- PURPOSE BAR -->
<div class="purpose-bar">
<strong>Goal:</strong> Differentiate <strong>Peripheral Vertigo</strong> (safe) from <strong>Central / Stroke</strong> (emergency) |
<strong>HINTS is more sensitive than CT scan in first 24–48 hrs</strong>
</div>
<!-- THREE SECTION CARDS -->
<div class="body">
<!-- H: HEAD IMPULSE TEST -->
<div class="section h-color">
<div class="section-header">
<div class="section-letter">H</div>
<div class="section-title-block">
<div class="section-name">Head Impulse<br>Test (HIT)</div>
<div class="section-action">Rapid 15° head turn while patient fixates on your nose</div>
</div>
</div>
<div class="section-body">
<div class="how-to">
<strong>How to perform</strong>
Hold patient's head. Ask them to stare at your nose. Rapidly turn head 10–15° to one side. Watch eyes carefully.
</div>
<div style="height:8px"></div>
<div class="result-row safe">
<div class="result-icon">✅</div>
<div class="result-content">
<div class="result-label">Positive HIT = PERIPHERAL</div>
<div class="result-finding">Corrective saccade visible</div>
<div class="result-meaning">Eyes drift with head, then snap back to your nose → Labyrinthine problem</div>
</div>
</div>
<div class="result-row danger">
<div class="result-icon">🚨</div>
<div class="result-content">
<div class="result-label">Negative HIT = CENTRAL ⚠</div>
<div class="result-finding">No corrective saccade</div>
<div class="result-meaning">Eyes stay locked on target despite head movement → STROKE until proven otherwise</div>
</div>
</div>
<div style="background:#fff3cd; border-left:3px solid #e67e22; border-radius:0 4px 4px 0; padding:5px 8px; margin-top:6px; font-size:10px; color:#7d4e00; line-height:1.4;">
⚠ <strong>Memory trick:</strong> "If the eye keeps up with the head = the ear is down (broken), it's peripheral = SAFE"
</div>
</div>
</div>
<!-- I: NYSTAGMUS -->
<div class="section i-color">
<div class="section-header">
<div class="section-letter">I</div>
<div class="section-title-block">
<div class="section-name">Nystagmus<br>Direction</div>
<div class="section-action">Observe eye movements in primary and lateral gaze</div>
</div>
</div>
<div class="section-body">
<div class="how-to">
<strong>How to perform</strong>
Watch patient's eyes at rest and when looking left, right, up, down. Note the fast-beat direction.
</div>
<div style="height:8px"></div>
<div class="result-row safe">
<div class="result-icon">✅</div>
<div class="result-content">
<div class="result-label">Unidirectional = PERIPHERAL</div>
<div class="result-finding">Beats in ONE direction only</div>
<div class="result-meaning">Nystagmus beats the same way regardless of gaze direction. Fatigues. Suppressed by fixation.</div>
</div>
</div>
<div class="result-row danger">
<div class="result-icon">🚨</div>
<div class="result-content">
<div class="result-label">Direction-Changing = CENTRAL ⚠</div>
<div class="result-finding">Beats CHANGE with gaze direction</div>
<div class="result-meaning">Beats right when looking right, beats left when looking left → Gaze-evoked nystagmus = cerebellar/brainstem</div>
</div>
</div>
<div style="background:#f3e5f5; border-left:3px solid #6a1b9a; border-radius:0 4px 4px 0; padding:5px 8px; margin-top:6px; font-size:10px; color:#4a148c; line-height:1.4;">
⚠ <strong>Also dangerous:</strong> Pure <em>vertical</em> nystagmus (up/down beating) is always central — refer immediately.
</div>
</div>
</div>
<!-- T: TEST OF SKEW -->
<div class="section t-color">
<div class="section-header">
<div class="section-letter">T</div>
<div class="section-title-block">
<div class="section-name">Test of Skew<br>(Cover-Uncover)</div>
<div class="section-action">Detect vertical ocular misalignment</div>
</div>
</div>
<div class="section-body">
<div class="how-to">
<strong>How to perform</strong>
Ask patient to fixate on your nose. Cover one eye with your hand for 3 seconds. Quickly uncover and watch for ANY vertical eye movement.
</div>
<div style="height:8px"></div>
<div class="result-row safe">
<div class="result-icon">✅</div>
<div class="result-content">
<div class="result-label">No Movement = PERIPHERAL</div>
<div class="result-finding">Eye stays in place on uncover</div>
<div class="result-meaning">No vertical deviation. Eyes are aligned. Brainstem pathways intact.</div>
</div>
</div>
<div class="result-row danger">
<div class="result-icon">🚨</div>
<div class="result-content">
<div class="result-label">Vertical Deviation = CENTRAL ⚠</div>
<div class="result-finding">Eye moves up OR down on uncover</div>
<div class="result-meaning">Skew deviation = brainstem lesion disrupting otolith-ocular pathways. Highly specific for stroke.</div>
</div>
</div>
<div style="background:#e8f5e9; border-left:3px solid #2e7d32; border-radius:0 4px 4px 0; padding:5px 8px; margin-top:6px; font-size:10px; color:#1b4332; line-height:1.4;">
✔ <strong>Tip:</strong> Repeat on other eye too. Any vertical refixation movement = abnormal = central.
</div>
</div>
</div>
</div>
<!-- RED ALERT BOX -->
<div class="alert-box">
<div class="alert-icon">🔴</div>
<div class="alert-content">
<div class="alert-title">⚠ ANY ONE CENTRAL SIGN = CENTRAL CAUSE UNTIL PROVEN OTHERWISE</div>
<div class="alert-text">
Central HINTS = Negative HIT +/or Direction-changing nystagmus +/or Vertical skew deviation
→ <strong>Urgent CT Brain</strong> (to exclude hemorrhage) → <strong>MRI Brain + MRA</strong> → <strong>Neurology referral immediately</strong>
</div>
</div>
</div>
<!-- BOTTOM COMPARISON + WHEN TO USE -->
<div class="bottom-row">
<div class="compare-box peripheral">
<div class="compare-title">
🟢 Peripheral Vertigo
<span class="compare-badge">SAFE</span>
</div>
<div class="compare-item">HINTS: Positive HIT + Unidirectional nystagmus + No skew</div>
<div class="compare-item">Triggered by head movement (BPPV) or after viral illness (neuritis)</div>
<div class="compare-item">Nystagmus fatigues, suppressed by visual fixation</div>
<div class="compare-item">Patient can walk (unsteady but manages)</div>
<div class="compare-item">No focal neuro signs, no headache, no diplopia</div>
<div class="compare-item" style="color:#1b5e20; font-weight:700;">→ Epley maneuver / Betahistine / Steroids</div>
</div>
<div class="compare-box central">
<div class="compare-title">
🔴 Central Vertigo
<span class="compare-badge">EMERGENCY</span>
</div>
<div class="compare-item">HINTS: Negative HIT and/or direction-changing nystagmus and/or skew</div>
<div class="compare-item">Sudden onset, not always position-triggered</div>
<div class="compare-item">Cannot walk / severe ataxia / falls to one side</div>
<div class="compare-item">Diplopia, facial numbness, dysarthria, dysphagia</div>
<div class="compare-item">Severe headache ("worst of life") = hemorrhage</div>
<div class="compare-item" style="color:#b71c1c; font-weight:700;">→ CT Brain → Aspirin 300mg → Refer neurology</div>
</div>
</div>
<!-- FOOTER -->
<div class="footer">
<strong>HINTS exam applies ONLY to Acute Vestibular Syndrome (constant vertigo > 1 day + nausea + gait instability)</strong> |
For episodic/positional vertigo → use Dix-Hallpike test instead |
Ref: Kattah JC et al. <em>Stroke</em> 2009; Newman-Toker DE et al. |
<strong>RIMS Adilabad Casualty — HINTS Quick Reference</strong>
</div>
</div>
</body>
</html>
cd /home/daytona/workspace/hints-card && chromium --headless --disable-gpu --no-…
HINTS Exam Card
PDF Document · PDF
HINTS Exam Card
HTML File · HTML
For loose stool standard treatment
| Sign | Mild | Moderate | Severe |
|---|---|---|---|
| General | Alert, active | Irritable, restless | Lethargic, unconscious |
| Eyes | Normal | Sunken | Very sunken, dry |
| Tears | Present | Reduced | Absent |
| Mouth/tongue | Moist | Dry | Very dry |
| Thirst | Normal | Thirsty | Drinks poorly / unable |
| Skin pinch | Returns immediately | Returns slowly (<2 sec) | Returns very slowly (>2 sec) |
| Urine | Normal | Dark, reduced | None for hours |
| Pulse | Normal | Fast, weak | Very fast, feeble |
| Action | ORS at home | ORS in OPD | IV fluids, admit |
WHO-modified ORS (245 mOsm) is the first-line treatment for most patients - Rosen's EM
"Antibiotic treatment can prolong shedding of Salmonella and is NOT indicated in most GI infections." - Rosen's EM
| Situation | Antibiotic |
|---|---|
| Dysentery (bloody + mucoid stool + fever) likely Shigella | Tab. Ciprofloxacin 500mg BD x 3 days OR Azithromycin 500mg OD x 3 days |
| Cholera (rice-water stools, severe dehydration, epidemic setting) | Tab. Doxycycline 300mg single dose (adult) OR Azithromycin 1g single dose |
| Giardia (chronic, frothy stools, travel history, no fever) | Tab. Metronidazole (Flagyl) 400mg TDS x 5-7 days |
| Amoebiasis (bloody stool, liver tenderness) | Tab. Metronidazole 800mg TDS x 5-10 days |
| C. difficile (post-antibiotic diarrhea, hospital-acquired) | Tab. Vancomycin 125mg oral QDS x 10 days (preferred) OR Metronidazole |
| Typhoid fever (sustained fever + constipation/diarrhea + relative bradycardia) | Tab. Azithromycin 1g OD x 5 days OR Cefixime 400mg BD x 7 days |
| Traveler's diarrhea | Tab. Azithromycin 1g single dose OR Ciprofloxacin 750mg single dose |
| Immunocompromised patient | Treat more aggressively, lower threshold |
| Step | Action |
|---|---|
| 1 | Assess dehydration - check skin pinch, eyes, pulse, urine output |
| 2 | Start ORS immediately (mild-mod) or IV RL (severe) |
| 3 | Ondansetron 4-8mg if vomiting |
| 4 | Zinc 20mg/day for all children < 5 yrs |
| 5 | Check for fever + blood in stool → if yes, consider antibiotics (Ciprofloxacin/Azithromycin) |
| 6 | No blood, no fever → NO antibiotics. Symptomatic treatment only |
| 7 | Loperamide only in adults with non-bloody, non-febrile diarrhea |
| 8 | Resume feeding early - do NOT starve |
| 9 | Admit if severe, not improving, or red flags present |
| 10 | Counsel on hand hygiene + ORS preparation at home |
Make a flowchart: when NOT to give antibiotics in diarrhea
A clean professional medical flowchart titled "DIARRHEA: When NOT to Give Antibiotics" designed as a laminated casualty reference card for an emergency department in India. The flowchart starts at the top with a box: "Patient presents with LOOSE STOOLS / DIARRHEA" Then a decision diamond: "Any of these present? Fever + Bloody/mucoid stool + Severe abdominal pain + Tenesmus" YES path (right side, orange/red): leads to "INVASIVE / BACTERIAL DIARRHEA suspected" → "Consider antibiotics - Ciprofloxacin / Azithromycin / Metronidazole based on pattern" NO path (down, green): leads to "Watery, non-bloody diarrhea, no fever" → another decision diamond: "Any RED FLAGS? Unable to drink, Altered consciousness, Infant < 3 months, Immunocompromised, >10 stools/day" From RED FLAGS: YES → "Admit, IV fluids, investigate, consider antibiotics if needed" NO path continues GREEN down to a large RED STOP sign box: "DO NOT GIVE ANTIBIOTICS" with subtext listing reasons: 1. Viral cause (Norovirus, Rotavirus) - most common cause, antibiotics useless 2. Food poisoning (Staph, B.cereus) - self-limiting 24hrs, antibiotics useless 3. Suspected E.coli O157/STEC - antibiotics INCREASE risk of HUS (kidney failure) 4. Salmonella (non-typhi) - antibiotics PROLONG carrier state 5. Simple traveler's diarrhea - self-limiting Below the STOP box, a green treatment box: "STANDARD TREATMENT ONLY: ORS/IV fluids + Zinc 20mg/day (children) + Ondansetron for vomiting + Early feeding + Hand hygiene counseling" At the bottom, a yellow warning banner: "REMEMBER: Most acute diarrhea is VIRAL. Antibiotics = resistance + side effects + no benefit" Color scheme: white background, green for safe/no-antibiotic pathway, red/orange for antibiotic-needed pathway, bold typography, clean medical infographic style. Suitable for A4 printing and laminating.
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Which medication can b prescriptied for pregnant women as per loose stool and vomiting ,fever and shivering
| Serious Cause | Clue |
|---|---|
| Sepsis in pregnancy | High fever, rigors, tachycardia, hypotension |
| Malaria | Rigors + fever + area endemic (like Adilabad) |
| Typhoid / Enteric fever | Sustained fever, relative bradycardia, step-ladder pattern |
| Pyelonephritis / UTI | Loin pain, burning urine, CVA tenderness |
| Listeria | Flu-like + diarrhea, risk to fetus (can cause fetal death) |
| Cholecystitis / Appendicitis | Right-sided pain - appendix is displaced upward in pregnancy |
| Drug | Dose | Safety | Notes |
|---|---|---|---|
| Vitamin B6 (Pyridoxine) | 10-25 mg every 8 hrs | ✅ Safest - first line | Very safe, no fetal risk |
| Doxylamine + Pyridoxine | 10mg + 10mg up to 4x/day | ✅ FDA approved in pregnancy | First-line pharmacologic anti-emetic in pregnancy (Diclegis / Unisom) |
| Metoclopramide (Perinorm) | 10 mg oral/IV/IM every 8 hrs (max 5 days) | ✅ Generally safe | Widely used, avoid prolonged use - extrapyramidal risk |
| Promethazine (Phenergan) | 12.5-25 mg every 4-6 hrs | ✅ Generally safe | Widely used in India; avoid in children < 2 yrs but acceptable in adults pregnant |
| Ondansetron (Zofran) | 4 mg oral/IV every 8 hrs | ⚠ Use cautiously | Widely used but recent data suggest possible fetal anomaly risk in first trimester. Prefer after 10 weeks. Use only if others fail. |
| Ginger | 250 mg every 6 hrs capsule/syrup | ✅ Safest non-drug | Good evidence for mild vomiting |
Practical first-line at your casualty: Metoclopramide 10mg IV/IM + Vitamin B6 25mg oral - safe in all trimesters
| Drug | Safety | Notes |
|---|---|---|
| ORS (Oral Rehydration Salts) | ✅ Completely safe | Priority - prevent dehydration |
| IV Ringer's Lactate | ✅ Safe | For severe dehydration |
| Zinc 20mg/day | ✅ Safe | If prescribed, generally acceptable |
| Loperamide | ⚠ Avoid in 1st trimester | Use only if clearly needed in 2nd/3rd trimester, avoid in bloody diarrhea |
| Bismuth subsalicylate | ❌ Avoid | Contains salicylate - fetal risk |
| Smectite (Smecta) | ✅ Safe | Not absorbed, safe in pregnancy |
Key principle: Hydration is the treatment. Most diarrhea in pregnancy resolves with ORS alone.
| Drug | Safety | Notes |
|---|---|---|
| Paracetamol (Acetaminophen) | ✅ Drug of choice - all trimesters | 500-1000 mg every 6-8 hrs, max 4g/day |
| Ibuprofen / Diclofenac (NSAIDs) | ❌ AVOID after 20 weeks | Risk of premature closure of ductus arteriosus, oligohydramnios, renal damage to fetus |
| Aspirin | ❌ Avoid (except low-dose 75mg for specific indications) | Risk of fetal bleeding, premature closure of ductus |
Always use Paracetamol for fever in pregnancy. Never NSAIDs.
| Antibiotic | Use For | Dose |
|---|---|---|
| Amoxicillin | UTI, mild infections | 500mg TDS x 5-7 days |
| Amoxicillin-Clavulanate (Augmentin) | Moderate infections | 625mg BD x 5-7 days |
| Azithromycin | Enteric infections, Chlamydia | 500mg OD x 3-5 days |
| Cephalexin (Cefalexin) | UTI, skin, mild-moderate infections | 500mg QDS x 7 days |
| Ceftriaxone | Severe infections, IV therapy | 1-2g IV OD - safe in pregnancy |
| Erythromycin | Respiratory, soft tissue (if penicillin allergic) | 500mg QDS x 7 days |
| Nitrofurantoin | UTI only | 100mg BD x 5-7 days - avoid at term (>36 weeks) |
| Drug | Reason | Alternative |
|---|---|---|
| Ciprofloxacin / any Fluoroquinolone | Damages fetal cartilage and joints | Azithromycin or Ceftriaxone |
| Tetracycline / Doxycycline | Stains fetal teeth, inhibits bone growth | Azithromycin |
| Metronidazole (Flagyl) | Avoid in 1st trimester (mutagenic in animal studies) | After 1st trimester, generally considered acceptable for amoebiasis/Giardia - use with caution, short course only |
| Trimethoprim (Septran/Co-trimoxazole) | Folate antagonist - neural tube defects | Nitrofurantoin for UTI |
| Chloramphenicol | Grey baby syndrome | Azithromycin / Ceftriaxone |
| Aminoglycosides (Gentamicin) | Fetal ototoxicity (deafness) | Ceftriaxone |
| Symptom | Safe Drug | Avoid |
|---|---|---|
| Fever | Paracetamol | NSAIDs, Aspirin |
| Vomiting | Metoclopramide, Vit B6 | Ondansetron in 1st trimester |
| Diarrhea | ORS, RL | Loperamide in 1st trimester |
| Bacterial infection | Azithromycin, Ceftriaxone, Amoxicillin | Ciprofloxacin, Tetracycline, Metronidazole (1st trimester) |
When in doubt in a pregnant patient - Paracetamol + ORS + Ceftriaxone IV covers most bases safely while you investigate further or arrange referral.