Electromyography

Electromyography (EMG) is a broad topic - could mean the basic overview, the testing procedure/technique, clinical indications, or how to interpret findings (e.g., for a specific condition). Let me narrow this down so I can give you the most useful answer.
I have enough to give a solid overview. I'll skip a PubMed check since this is a well-established, non-controversial physiologic/diagnostic concept with no fast-moving evidence base.

Electromyography (EMG) - Overview

What it is
Electromyography is an electrodiagnostic technique that records the electrical activity of skeletal muscle, most commonly using a needle (concentric) electrode inserted directly into the muscle, though surface electrodes over the skin can also be used for some applications. It assesses the properties of the motor unit (a motor neuron and all the muscle fibers it innervates), and is typically paired with nerve conduction studies (NCS) as part of a combined electrodiagnostic exam - the NCS component measures how nerves conduct impulses, while EMG measures the muscle's electrical response - Goldman-Cecil Medicine, p. 275; Firestein & Kelley's Textbook of Rheumatology.
The four phases examined during needle EMG
  1. Insertional activity - the brief burst of electrical activity that occurs in the first second after the needle is inserted into muscle
  2. Spontaneous activity - electrical activity recorded at rest (should normally be silent)
  3. Voluntary activity - motor unit potentials generated during active muscle contraction
  4. Recruitment pattern - how electrical activity changes as contraction intensity increases (i.e., how many/which motor units are recruited)
  • Goldman-Cecil Medicine, p. 275
Key abnormal findings and what they suggest
FindingTypical cause
Prolonged insertional activityAcute denervation or active inflammatory myopathy
Fibrillations / positive sharp wavesAcute denervation, active inflammatory myopathy
FasciculationsChronic neuropathy, motor neuron disease
Myotonic dischargesMyotonic disorders, acid maltase deficiency
Large-amplitude, long-duration, polyphasic ("neuropathic") potentialsChronic neuropathy, anterior horn cell disease
Small-amplitude, short-duration, polyphasic ("myopathic") potentialsChronic myopathy, neuromuscular junction disorders
Reduced recruitmentChronic neuropathic disorders
Rapid/early recruitmentChronic myopathies
  • Goldman-Cecil Medicine, p. 275-276
Why it's clinically useful
  • EMG helps localize the source of weakness - anterior horn cell (e.g., motor neuron disease), nerve root (radiculopathy), plexus (plexopathy), a single peripheral nerve (mononeuropathy), or multiple nerves (polyneuropathy) - versus a primary muscle disorder.
  • It distinguishes active inflammatory myopathies (dermatomyositis, polymyositis, inclusion body myositis) from chronic/structural myopathies, and is sensitive (though nonspecific) for detecting muscle pathology in general - Firestein & Kelley's Textbook of Rheumatology, p. 4435.
  • It's used to guide muscle biopsy site selection in suspected myositis, since inflammation is often patchy - the biopsy is typically taken from the contralateral, non-EMG-tested muscle because needle EMG itself can cause histologic artifact that confounds biopsy interpretation - Firestein & Kelley's Textbook of Rheumatology, p. 4435-4436.
  • Combined with repetitive nerve stimulation, it can diagnose neuromuscular junction disorders: myasthenia gravis shows a decrementing response with repetitive stimulation, while presynaptic myasthenic syndromes (e.g., Lambert-Eaton) show an incrementing response with fast repetitive stimulation - Goldman-Cecil Medicine, p. 274.
Important caveat: no single EMG finding is pathognomonic (diagnostic on its own) for any specific disease - results must be interpreted alongside the clinical picture, nerve conduction data, and often muscle biopsy or serology - Goldman-Cecil Medicine, p. 275.
Here's a real clinical photo set illustrating fine-wire/needle electrode placement used for EMG-type recordings:
Fine-wire EMG electrode placement technique
Let me know if you'd like more detail on the actual testing procedure/patient experience, or on interpreting EMG in a specific condition (e.g., carpal tunnel syndrome, ALS, myopathy work-up).
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