Q: How often to change pillow cover for prevention of pimples A: For acne prevention, a good practical rule is: - Change pillowcase every 2 to 3 days if you’re acne-prone - Daily if your skin is very oily, you sweat at night, or you use heavy hair/skin products - At least weekly is the minimum for most people, but often not enough for frequent breakouts Helpful extras: - Wash pillowcases in a gentle, fragrance-free detergent - Avoid fabric softener if it irritates your skin - Keep hair clean and off your face at night - Change face towel often too daily is best If pimples continue despite this, a simple acne routine benzoyl peroxide or salicylic acid, plus non-comedogenic moisturizer usually helps.