-47. All of the following statements regarding liver function tests are true EXCEPT: A. B. Alanine aminotransferase (ALT) is found in liver, cardiac muscle, skeletal muscle, and kidney. Elevation of aspartate aminotransferase (AST) and ALT to >1000 IU/L is typical of ischemic hepatitis. C. D. E. Elevation of AST is more specific for liver dysfunction than elevation of ALT. Increased AST and ALT with an AST:ALT ratio of >3 is typical of acute viral hepatitis. The magnitude of elevated AST and ALT has important prognostic significance in acute hepatitis.