Cervical sympathectomy

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cervical sympathectomy

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cervical sympathectomy indications complications Horner syndrome thoracic sympathectomy guideline

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https://pmc.ncbi.nlm.nih.gov/articles/PMC6491249

Cervical sympathectomy is surgical interruption or removal of part of the cervical or cervicothoracic sympathetic chain. It reduces sympathetic outflow to the head, neck, upper limb, and heart.

Current clinical roles

  • Refractory ventricular arrhythmias / VT storm: left-sided or bilateral cardiac sympathetic denervation may be considered at specialist centers after antiarrhythmic drugs and catheter ablation have failed. A stellate ganglion block is often used first to assess short-term response. The Washington Manual of Medical Therapeutics, p. 259.
  • Historically for upper-limb vasospastic disease such as severe Raynaud phenomenon. Open cervical sympathectomy was generally unsuccessful and is largely obsolete. Bailey and Love's Short Practice of Surgery, p. 1045.
  • In severe Raynaud-related digital ischemia, local digital sympathectomy is generally preferred when surgery is considered. Cervical or thoracic procedures may give initial relief but symptoms can recur within 12-18 months. Andrews' Diseases of the Skin, p. 589.
  • Modern endoscopic thoracic sympathectomy, rather than an open cervical operation, is selectively used for severe refractory palmar or axillary hyperhidrosis. Bailey and Love's Short Practice of Surgery, p. 1045.

Important adverse effects

  • Horner syndrome from injury near the stellate ganglion: ptosis, miosis, and reduced facial sweating on the affected side
  • Compensatory or gustatory sweating
  • Pneumothorax, bleeding, neuralgia, infection
  • Hypotension and altered temperature regulation
  • Recurrence or incomplete benefit
For neuropathic pain or complex regional pain syndrome, evidence for surgical or chemical sympathectomy is weak; it should be reserved for carefully selected patients only after other options have failed, as summarized in a Cochrane review.

Surgical management of lower GI Bleed

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lower gastrointestinal hemorrhage management

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ACG guideline acute lower gastrointestinal bleeding surgery embolization colectomy 2023

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PMID: 38364312

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https://pubmed.ncbi.nlm.nih.gov/36735555

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Surgical management of acute lower GI bleeding

Surgery is uncommon and is a last-resort, life-saving option after resuscitation, localization, endoscopic treatment, and interventional radiology have failed.

1. Initial principles before operation

  • ABC resuscitation, two large-bore IV lines, cross-match blood, correct coagulopathy, and stop/reverse anticoagulants when appropriate.
  • A patient with massive hematochezia and shock may have an upper GI source. Consider urgent upper endoscopy when suspected.
  • Localize the bleeding source whenever possible:
    • Colonoscopy in stable patients
    • CT angiography for brisk ongoing bleeding or instability
    • Catheter angiography with superselective embolization after positive CTA or when colonoscopy is not feasible
  • Early involvement of colorectal/general surgery and interventional radiology is appropriate in severe bleeding.
Most diverticular bleeds stop spontaneously. For severe bleeding that cannot be managed colonoscopically, CTA followed by selective angiography and embolization is preferred before surgery. Mulholland and Greenfield’s Surgery, pp. 3230-3231.

2. Indications for surgery

Operate when there is:
  1. Persistent massive bleeding with hemodynamic instability despite aggressive resuscitation.
  2. Failure of endoscopic hemostasis and angiographic embolization, or when these facilities are unavailable.
  3. Recurrent severe bleeding refractory to endoscopic and angiographic treatment.
  4. A large ongoing transfusion requirement, often cited as more than 6 units of blood products with continued bleeding.
  5. A surgically correctable lesion, such as:
    • Bleeding colorectal cancer
    • Meckel diverticulum
    • Ischemic or perforated bowel
    • Persistent severe hemorrhoidal bleeding in selected cases
Current Surgical Therapy, p. 322.

3. Choice of operation

Bleeding site/statusOperation
Definitively localized colonic sourceSegmental colectomy containing the lesion
Localized small-bowel lesionSegmental small-bowel resection
Bleeding lesion marked at colonoscopySegmental colectomy guided by endoscopic tattoo/clip
Life-threatening colonic bleed, source not localizedSubtotal colectomy, usually with end ileostomy in an unstable patient
Very unstable, coagulopathic patientDamage-control laparotomy, control hemorrhage, temporary abdominal closure, ICU resuscitation, planned relook operation
Rectal or anorectal sourceSource-specific treatment, for example transanal ligation, hemorrhoidectomy, or other rectal procedure

A. Segmental colectomy

Preferred operation if the bleeding site has been reliably localized by colonoscopy, CTA/angiography, or intraoperative colonoscopy.
  • Resect the involved colonic segment with appropriate vascular control.
  • Restore continuity with primary anastomosis only if physiology and bowel perfusion are favorable.
  • In shock, gross contamination, severe coagulopathy, or high vasopressor requirement, perform resection with stoma formation rather than a risky primary anastomosis.
Key rule: Do not perform a blind segmental colectomy based merely on diverticula being present in one segment. Diverticulosis is often widespread and the actual bleeding site may lie elsewhere.

B. Subtotal colectomy

Indicated only for ongoing, life-threatening presumed colonic hemorrhage when localization is impossible and less invasive control has failed or cannot be undertaken.
  • Removes colon from caecum to sigmoid/upper rectum.
  • Reconstruction options:
    • End ileostomy in unstable or coagulopathic patients
    • Ileorectal anastomosis in carefully selected stable patients
  • Before committing to subtotal colectomy, consider on-table colonoscopy or examination of the rectosigmoid to exclude a distal source.
Subtotal colectomy has a low rebleeding rate but appreciable physiological cost and perioperative risk. Sleisenger and Fordtran’s Gastrointestinal and Liver Disease, p. 2459.

4. Intraoperative adjuncts

When the source remains uncertain:
  • Intraoperative colonoscopy after lavage
  • Palpation and inspection of bowel
  • Enterotomy with intraoperative enteroscopy if a small-bowel source is suspected
  • Review preoperative CTA, angiographic images, endoscopic clips, or tattoo marks
  • Examination of rectum and anus before a “blind” colectomy

5. Postoperative care

  • ICU monitoring in massive-bleeding cases
  • Monitor hemoglobin, hemodynamics, urine output, lactate, and evidence of recurrent hemorrhage
  • Correct hypothermia, acidosis, thrombocytopenia, and coagulopathy
  • Watch for anastomotic leak, bowel ischemia, abdominal compartment syndrome, renal failure, and pulmonary complications
  • Restart antithrombotic therapy only after balancing rebleeding against thrombotic risk with the relevant specialists.

Exam summary

Resuscitate, localize, treat by endoscopy or embolization, then operate only for persistent or recurrent uncontrolled bleeding.
Localized lesion: segmental resection.
Unlocalized, exsanguinating presumed colonic bleed: subtotal colectomy, usually with stoma in an unstable patient.
Never perform blind segmental colectomy.
The 2023 ACG guideline also emphasizes the growing role of CTA and prompt transcatheter embolization in severe lower GI bleeding. A 2024 meta-analysis of embolization reported pooled technical success of 97%, rebleeding of 20.7%, and post-embolization ischemia of 7.5%, supporting embolization as an important surgery-sparing step.
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