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Urodynamic Report Analysis — Rao, Jayesh (Male, 57 years, DOB: 23/12/1968)

Study: Pressure-flow study | Date: 30/04/2026 | Centre: Sujay Urological Hospital | Investigator: Dr. Ajay Bhandarkar

1. Patient Demographics & Study Overview

ParameterValue
Age57 years, Male
Study typePressure-flow urodynamics (4-channel)
ChannelsEMG, Pves, Pabd, Pdet, Qura

2. Filling Phase Analysis

Volumes

ParameterValueInterpretation
Infused volume409 ml
Volume lost through leakage16 mlSmall leak noted
Effective bladder filling (MCC)393 mlLow-normal

Bladder Sensations

SensationVolume (ml)Comment
First sensation119 mlNormal (typically 100–200 ml)
First desire203 mlNormal
Normal desire295 mlNormal
Strong desire388 mlNormal
Urgency392 mlNear capacity — urgency only at MCC
MCC393 mlLow-normal capacity
Comment: Sensations are preserved and proportionately scaled. Urgency appearing only at MCC (392/393 ml) is consistent with a compliant bladder that fills adequately but has difficulty emptying.

Detrusor Pressures During Filling

  • Pdet values during filling remain low (5–18 cmH₂O range) with no significant spontaneous rise
  • No detrusor overactivity (DO) is demonstrated during the filling phase — the Pdet trace is flat
  • The 16 ml leakage likely represents stress or positional leak, not DO-related urgency incontinence

Compliance

  • Compliance result (linear regression): Pdet slope = 67.8 ml/cmH₂O (Begin 2 ml → End 100 ml)
  • Normal bladder compliance (normal >20 ml/cmH₂O; values >40 are very good)
  • The bladder fills at low pressure — no impaired compliance

3. Voiding Phase Analysis — THE KEY FINDING

Voiding Phase Results

ParameterValueNormalInterpretation
Total bladder capacity393 mlNormal
Qmax4.2 ml/s>15 ml/sSeverely reduced
Time to Qmax105 s<30 sGrossly prolonged
Pdet.Qmax28 cmH₂OSee below
Voided volume1 ml~393 ml expectedNear-complete retention
Flow time12 s
Voiding time155 s
Hesitancy110 s<10 sMarkedly prolonged
Average flow rate0.1 ml/s>10 ml/sCritically low
Computed residual urine392 ml<50 mlMassive PVR — near total retention
This is the dominant finding: The patient voided only 1 ml out of 393 ml bladder capacity, leaving a post-void residual (PVR) of 392 ml. This represents near-complete urinary retention or severely impaired voiding.

4. Nomogram & Obstruction Classification

Siroky Nomogram

  • Both Qmax (4 ml/s) and average flow rate (0 ml/s) plot well below −3 SD (hatched zone)
  • This confirms severely abnormal voiding function

Liverpool Nomogram

  • The voided volume of 1 ml at Qmax of 4 ml/s plots in the lowest percentile (<5th percentile)
  • Severely below normal for a bladder volume of 393–600 ml

ICS Detrusor-Flow Plot (Abrams-Griffiths / BOOI)

  • BOOI = PdetQmax − 2(Qmax) = 28 − 2(4.2) = 28 − 8.4 = 19.6
  • BOOI interpretation: ≥40 = Obstructed, 20–40 = Equivocal, ≤20 = Unobstructed
  • BOOI of ~20 falls at the equivocal/unobstructed boundary
  • The obstructed slope = 6.50 cmH₂O/(ml/s); A/G number = 20 (equivocal)
  • The tracing on the ICS plot shows the voiding point is in the equivocal zone, not clearly obstructed

Critical Interpretation of the Pressure-Flow Paradox

  • Qmax is severely reduced (4.2 ml/s) but Pdet.Qmax is only moderately raised (28 cmH₂O)
  • This combination — low flow + low/moderate detrusor pressure — is the hallmark of detrusor underactivity (DU) rather than pure bladder outlet obstruction (BOO)
  • If BOO were the dominant cause, one would expect high Pdet with low Qmax
  • Here, the detrusor fails to generate adequate pressure to overcome even normal urethral resistance
Primary diagnosis: Detrusor Underactivity (Impaired Detrusor Contractility) with near-complete urinary retention

5. EMG Assessment

  • The EMG channel (surface/sphincter) shows artefact-heavy traces but no overt dyssynergia pattern is clearly identifiable
  • No definitive Detrusor-External Sphincter Dyssynergia (DESD) is evident, though artefact limits full interpretation

6. Cough Tests (Quality Control)

Cough markers show:
  • Pves and Pabd spikes are concordant (rise together) — confirming correct catheter placement
  • Pdet artefacts are near-zero during coughs — good catheter calibration and placement
  • Study quality is satisfactory

7. Summary Interpretation

DomainFinding
Filling phaseNormal — no detrusor overactivity, good compliance (67.8 ml/cmH₂O)
Bladder capacityLow-normal MCC of 393 ml
SensationsNormal and preserved
Voiding phaseCatastrophic failure — voided only 1 ml, PVR 392 ml
QmaxSeverely reduced at 4.2 ml/s
Pdet.QmaxLow-normal at 28 cmH₂O
BOOI (A/G number)20 — equivocal, not clearly obstructed
ICS nomogramEquivocal zone
Primary diagnosisDetrusor Underactivity / Acontractile or Underactive Detrusor
ObstructionCannot be excluded but not the primary mechanism

8. Clinical Implications & Recommendations

  1. Urinary retention management: Given PVR of 392/393 ml, clean intermittent catheterisation (CIC) is the immediate priority. Indwelling catheter may be needed short-term.
  2. Neurological evaluation: Detrusor underactivity at 57 years in a male warrants evaluation for:
    • Diabetic cystopathy (if diabetic)
    • Spinal cord pathology (lumbar canal stenosis, cauda equina)
    • Peripheral neuropathy
    • Post-obstructive decompensation (chronic BPH causing bladder fatigue)
  3. PSA + prostate evaluation: Despite equivocal BOOI, BPH/prostate pathology should be assessed — even if not the primary cause, a significant outlet component can worsen DU
  4. Alpha-blockers: A trial may help reduce outlet resistance to assist the weakened detrusor; however, if detrusor is acontractile, benefit will be limited
  5. Repeat urodynamics after catheterisation-based bladder rest may be considered — decompression of a chronically over-distended bladder can sometimes partially restore contractility
  6. Avoid surgery (e.g., TURP) unless outlet obstruction is confirmed, as operating on a patient with DU without obstruction carries risk of worsening retention

Reference

BOOI calculation and nomogram interpretation per ICS provisional nomogram (Griffiths et al., 1997; Lim and Abrams, 1995) — Campbell-Walsh-Wein Urology, Chapter 114.
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