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Lab Reports - Full Explanation
Patient: Mrs. Roshani Sen | 26-year-old Female | UHID: PSH-677845
Hospital: Parul Sevashram Hospital, Vadodara (ISO 15189:2022 Accredited Laboratory)
Referring Doctor: Dr. Dipesh D. Duttaroy
The reports span from admission (9 June 2026) through the post-operative ICU period (17-19 June 2026), concluding with the histopathology report (22 June 2026). Here is a test-by-test breakdown:
BATCH 1 - Admission Workup (9 June 2026)
1. Complete Blood Count (CBC)
| Parameter | Result | Reference | Interpretation |
|---|
| Haemoglobin | 11.7 g/dL ⬇ | 12.0-15.0 | Mildly low - mild anaemia |
| RBC Count | 4.20 million/µL ⬇ | 4.5-5.5 | Low |
| Haematocrit (HCT) | 36.1% ⬇ | 40-54% | Low |
| MCV | 86.0 fL | 83-101 | Normal - normocytic anaemia |
| MCH | 27.9 pg | 27-32 | Normal |
| MCHC | 32.4 g/dL | 31.5-34.5 | Normal |
| WBC | 5710/µL | 4000-10000 | Normal |
| Neutrophils | 60% | 50-62% | Normal |
| Lymphocytes | 32.2% | 20-40% | Normal |
| Platelets | 278,000/µL | 150,000-450,000 | Normal |
Summary: She has mild normocytic anaemia on admission. No infection signal (WBC and differential normal). Likely anaemia of chronic disease from the mediastinal mass.
2. C-Reactive Protein (CRP)
| Test | Result | Reference |
|---|
| CRP | 1.64 mg/L | <5.0 mg/L ✅ |
Normal. No significant systemic inflammation at the time of admission. The mediastinal mass was not causing active inflammation/infection at this stage.
3. Thyroid Function Test (TFT)
| Test | Result | Reference |
|---|
| TSH | 1.920 µIU/mL | 0.589-6.880 ✅ |
Normal thyroid function. This was checked to rule out a thyroid origin of the anterior neck/mediastinal mass (e.g., substernal goitre). TSH being normal and the CT scan appearance pointed away from a thyroid lesion.
4. NT-proBNP (Heart Failure Marker)
| Test | Result | Reference |
|---|
| NT-proBNP | 38.8 pg/mL | <300 pg/mL ✅ |
Normal. Rules out heart failure or significant cardiac compression by the mediastinal mass. Important pre-op check given the mass was sitting near the heart.
5. Procalcitonin (PCT)
| Test | Result | Reference |
|---|
| PCT | 0.05 ng/mL | 0-0.5 ✅ |
Normal. No evidence of bacterial sepsis or serious infection.
6. High-Sensitive Troponin I (Cardiac Troponin)
| Test | Result | Reference |
|---|
| Troponin I (hs) | <1.5 ng/L | 0-19 ng/L ✅ |
Normal. No cardiac muscle injury. Rules out myocardial involvement from the mediastinal mass.
7. Infectious Disease Screening
| Test | Result | Interpretation |
|---|
| HBsAg | 0.14 s/CO (Negative) | No Hepatitis B ✅ |
| Anti-HCV | 0.020 s/CO (Non-Reactive) | No Hepatitis C ✅ |
| HIV 1 & 2 | Non-Reactive (all 3 tests) | HIV Negative ✅ |
All three pre-operative mandatory infectious disease screens are negative - standard requirement before any surgery.
8. Kidney Function Test (KFT)
| Parameter | Result | Reference |
|---|
| Serum Creatinine | 0.6 mg/dL | 0.52-1.04 ✅ |
| eGFR | 120.8 mL/min | ≥90 (Stage 1) ✅ |
| Serum Urea | 24.90 mg/dL | 15.0-36.3 ✅ |
| BUN | 11.64 mg/dL | 8-23 ✅ |
| Uric Acid | 3.8 mg/dL | 2.5-6.2 ✅ |
Normal kidney function. Safe for surgery and anaesthesia drug clearance.
9. Coagulation Profile - APTT & PT/INR (9 June 2026)
| Test | Result | Reference |
|---|
| APTT | 32.8 sec | 22.7-35.0 ✅ |
| APTT Control | 31.0 sec | |
| PT (Patient) | 12.8 sec | 9.39-12.91 ✅ |
| INR | 1.13 ⬆ (slightly) | 0.8-1.1 |
APTT is normal. INR is mildly elevated at 1.13 (just above the upper limit of 1.1). This is a borderline finding suggesting a very mild tendency toward slower clotting, possibly related to nutritional status or early anaemia. The surgical team would have noted this but it is not a contraindication to surgery at this level.
BATCH 2 - Pre-Operative Repeat Workup (13 June 2026)
A second set of tests was run 4 days after admission (just before surgery on 16 June).
10. CBC (13 June)
| Parameter | Result | Change from Admission |
|---|
| Haemoglobin | 11.9 g/dL ⬇ | Slightly improved (+0.2) |
| RBC | 4.28 million ⬇ | Similar |
| Platelets | 290,000 | Normal |
| WBC | 5340 | Normal |
Anaemia persisted, essentially unchanged. Blood transfusion was ordered prior to surgery (as seen in the hospital records).
11. HbA1c (Glycated Haemoglobin)
| Test | Result | Interpretation |
|---|
| HbA1c | 4.8% | Non-diabetic ✅ (<5.7%) |
| Mean 3-month glucose (estimated) | ~91 mg/dL | Normal |
No diabetes. Checked because intraoperative blood glucose tends to rise under anaesthetic stress; knowing she is non-diabetic helps manage this.
12. CRP & TSH repeat (13 June)
| Test | Result | Change |
|---|
| CRP | 1.58 mg/L | Stable (still normal) |
| TSH | 1.550 µIU/mL | Normal (slightly lower, still normal) |
Both unchanged and within normal limits.
13. NT-proBNP, PCT, Troponin (13 June)
| Test | Result |
|---|
| NT-proBNP | 44.1 pg/mL ✅ (slightly higher, still normal) |
| PCT | 0.01 ng/mL ✅ |
| Troponin I | <1.5 ng/L ✅ |
All remain normal. No cardiac strain, no infection.
14. Electrolytes (13 June)
| Test | Result | Reference |
|---|
| Sodium (Na+) | 135.2 mmol/L ⬇ | 137-145 (just below normal) |
| Potassium (K+) | 4.30 mmol/L ✅ | 3.5-5.1 |
| Chloride (Cl-) | 108.00 mmol/L ⬆ | 98-107 (mildly high) |
Sodium is mildly low (hyponatraemia), and chloride slightly high. This pattern (low Na, high Cl) can occur with normal saline IV fluids or mild dehydration. Nothing dangerous, but the surgical team would have corrected this before the operation.
15. RPR (Syphilis Screen) - 13 June
| Test | Result |
|---|
| RPR | Non-Reactive ✅ |
No syphilis. Standard pre-op screen.
16. Liver Function Tests (13 June)
| Parameter | Result | Reference |
|---|
| Total Bilirubin | 0.7 mg/dL ✅ | 0.2-1.3 |
| SGPT (ALT) | 14.0 U/L ✅ | 0-35 |
| SGOT (AST) | 19.0 U/L ✅ | 14-36 |
| ALP | 87.0 U/L ✅ | 44-107 |
| Total Protein | 7.10 g/dL ✅ | 6.3-8.2 |
| Albumin | 3.90 g/dL ✅ | 3.5-5.0 |
Normal liver function. Liver enzymes and protein levels are healthy. Good nutritional/liver reserve going into surgery.
17. Urine Examination (13 June)
| Parameter | Result |
|---|
| Colour | Pale Yellow (normal) |
| Appearance | Clear |
| pH | 6.0 (normal) |
| Protein | Absent ✅ |
| Glucose | Absent ✅ |
| Blood | Trace (minimal) |
| Pus Cells | Occasional ✅ |
| RBCs | 2-4 cells/HPF (normal) |
Essentially normal urine. The trace blood and occasional cells are within acceptable limits. No urinary tract infection or kidney disease.
18. KFT Repeat (13 June)
| Parameter | Result | Change |
|---|
| Creatinine | 0.6 mg/dL ✅ | Unchanged |
| eGFR | 120.8 mL/min ✅ | Normal |
| BUN/Cr ratio | 20.02 ⬆ | Slightly above 20 (upper limit) |
Kidneys remain healthy. The marginally elevated BUN/Creatinine ratio can indicate mild dehydration.
BATCH 3 - Post-Operative ICU Period (17-19 June 2026)
Surgery was performed on 16 June 2026. Post-op monitoring took place in the CICU-CVTS (Cardiac ICU).
19. CBC Post-Op - Day 1 (17 June)
| Parameter | Result | Change |
|---|
| Haemoglobin | 10.3 g/dL ⬇ | Dropped from 11.9 pre-op |
| RBC | 3.75 million ⬇ | Dropped |
| Haematocrit | 32.2% ⬇ | Low |
| Neutrophils | 74.3% ⬆ | High (normal: 50-62%) |
| Lymphocytes | 18.1% ⬇ | Low |
| Platelets | 175,000 | Low-normal |
Expected post-surgical changes:
- Drop in Hb from 11.9 → 10.3 = surgical blood loss (~1.6 g/dL drop, consistent with major thoracic surgery)
- Neutrophilia (74.3%) is a normal stress response to surgery - the body releases neutrophils after any major procedure
- Lymphopenia (low lymphocytes) is also a typical post-surgical immune shift
- Blood transfusions were given (as documented in the surgical records) which helped maintain Hb from dropping further
20. Electrolytes Post-Op Day 1 (17 June)
| Test | Result | Reference |
|---|
| Sodium | 138.2 mmol/L ✅ | Back to normal |
| Potassium | 3.70 mmol/L ✅ | Normal |
| Chloride | 108 mmol/L ⬆ | Still mildly high |
Sodium corrected nicely after IV fluids. Potassium maintained safely (critical in cardiac ICU patients).
21. LFT Post-Op Day 1 (17 June)
| Parameter | Result | Change |
|---|
| SGOT (AST) | 39 U/L ⬆ | Above normal (14-36) |
| Albumin | 2.60 g/dL ⬇ | Low (was 3.9 pre-op) |
| Total Protein | 5.00 g/dL ⬇ | Low (was 7.1) |
| SGPT, Bilirubin, ALP | Normal | Unchanged |
Key post-op findings:
- Low albumin (2.6 g/dL) - This is very common after major surgery. Albumin drops due to dilution from IV fluids, redistribution to tissues (third-spacing), and the acute inflammatory response. It contributes to post-op oedema and can affect drug binding.
- Mildly elevated SGOT - AST is released from skeletal muscle, heart muscle, and liver. After thoracic surgery, mild elevation is expected from muscle/tissue handling. The SGPT (liver-specific) remains normal, so this is not a liver injury signal.
22. KFT Post-Op Day 1 (17 June)
| Test | Result |
|---|
| Creatinine | 0.7 mg/dL ✅ |
| eGFR | 101.1 mL/min ✅ |
Kidneys functioning well post-surgery. No acute kidney injury.
23. CBC Post-Op Day 2 (18 June)
| Parameter | Result | Change |
|---|
| Haemoglobin | 10.7 g/dL | Slightly improved (+0.4 from Day 1) |
| WBC | 7070 | Normal |
| Neutrophils | 80.6% ⬆ | Still elevated (post-op response) |
| Lymphocytes | 12.6% ⬇ | Low (lymphopaenia persisting) |
| Platelets | 160,000 | Low-normal |
Hb improving with transfusion/recovery. Neutrophilia continuing - expected in the first few post-operative days.
24. Potassium & KFT (18 June)
| Test | Result |
|---|
| K+ | 3.80 mmol/L ✅ |
| Creatinine | 0.6 mg/dL ✅ |
| Urea | 13.80 mg/dL ⬇ (slightly low) |
Kidneys excellent. Low urea reflects good hydration status in ICU.
25. CBC Post-Op Day 3 (19 June)
| Parameter | Result | Change |
|---|
| Haemoglobin | 9.8 g/dL ⬇ | Dropped again - likely haemodilution from IV fluids |
| Neutrophils | 71.7% ⬆ | Still elevated |
| Lymphocytes | 18.0% ⬇ | Low |
| Platelets | 160,000 | Borderline |
Hb dip on Day 3 may reflect post-transfusion dilution. The post-surgical neutrophilia is gradually resolving. Still no sign of infection (WBC total is 4870, within normal range despite neutrophilia).
MOST IMPORTANT REPORT - Histopathology (22 June 2026)
Report No. 1917/26
Specimen: Mediastinal mass (removed 16 June 2026)
CT findings (pre-op, 26 May 2026):
- Large, well-defined mixed-density mass: 8.3 × 5.1 × 12.2 cm
- Involving the lower neck and retrosternal region
- Contains fat, calcification, and soft tissue - classic CT appearance of a mature cystic teratoma
Gross examination (what the pathologist saw):
- Specimen measured 14 × 7.0 × 4.7 cm (quite large)
- External surface smooth
- On cutting: cheesy necrotic material drained from cystic areas
- Hair shafts visible inside the tumour
Microscopic findings:
The pathologist examined multiple tissue samples (labelled A through M) and found:
- Stratified squamous epithelium with sebaceous (oil) glands and keratin flakes
- Glands with papillary structures and fibrovascular cores
- Adipose (fat) tissue and fibrous stroma
- Inflammatory cells (lymphocytes and plasma cells)
- Mucinous epithelium with goblet cells (intestinal-type lining)
- Pseudostratified ciliated columnar epithelium (respiratory-type lining)
- Nerves, cartilage, and cholesterol clefts
- Hemosiderin-laden macrophages (evidence of old bleeding inside the tumour)
- Congested blood vessels and lymphoid aggregates
- No immature (malignant) elements found
Final Diagnosis:
✅ MATURE CYSTIC TERATOMA - Mediastinal Mass
This is the most important result. A mature cystic teratoma (also called a dermoid cyst in other locations) is a benign tumour arising from germ cells, containing derivatives of all three embryonic germ layers (ectoderm, mesoderm, endoderm) - hence the presence of skin, hair, fat, cartilage, respiratory lining, and intestinal lining all within one tumour. The absence of immature elements confirms it is not malignant. Complete surgical excision (which was performed) is curative.
Summary Table - All Tests at a Glance
| Test | 9 Jun | 13 Jun | 17 Jun (POD-1) | 18 Jun (POD-2) | 19 Jun (POD-3) |
|---|
| Hb (g/dL) | 11.7 ⬇ | 11.9 ⬇ | 10.3 ⬇⬇ | 10.7 ⬇ | 9.8 ⬇ |
| WBC (/µL) | 5710 ✅ | 5340 ✅ | 7270 ✅ | 7070 ✅ | 4870 ✅ |
| Neutrophils | 60% ✅ | 55.9% ✅ | 74.3% ⬆ | 80.6% ⬆ | 71.7% ⬆ |
| Platelets | 278K ✅ | 290K ✅ | 175K ✅ | 160K ✅ | 160K ✅ |
| CRP | 1.64 ✅ | 1.58 ✅ | - | - | - |
| Creatinine | 0.6 ✅ | 0.6 ✅ | 0.7 ✅ | 0.6 ✅ | 0.6 ✅ |
| Albumin | - | 3.9 ✅ | 2.6 ⬇⬇ | - | - |
| INR | 1.13 ⬆ | - | - | - | - |
| Troponin | Normal ✅ | Normal ✅ | - | - | - |
| HIV/HBsAg/HCV | All negative | All negative | - | - | - |
| Histopathology | - | - | - | - | Mature Cystic Teratoma (benign) ✅ |
Overall conclusion: All her pre-operative labs confirmed she was fit for surgery - no diabetes, no infection, no cardiac/liver/kidney dysfunction, no blood-borne viruses. The post-op trend is exactly what is expected after major thoracic surgery - a drop in Hb, post-surgical neutrophilia, and a transient drop in albumin. The histopathology report (the final and most significant result) confirmed a benign mature cystic teratoma, meaning the surgery was curative and no further oncological treatment is required.