Presentation on propofol with full details and all the doses
Propofol Complete Reference
Presentation · PPTX
| # | Slide |
|---|---|
| 1 | Title slide |
| 2 | Overview & Formulation |
| 3 | Mechanism of Action (GABA-A, NMDA, ion channels) |
| 4 | Pharmacokinetics (distribution, clearance, metabolism) |
| 5 | PK Model & Drug Interactions (midazolam, alfentanil, CYP3A4) |
| 6 | Doses — Quick Reference Table (all indications) |
| 7 | Induction — Detailed Dosing (adults, elderly, children) |
| 8 | Maintenance — TIVA & Sedation Dosing |
| 9 | CNS Effects (BIS targets, ICP, anticonvulsant, EEG) |
| 10 | Cardiovascular Effects (two-column) |
| 11 | Respiratory Effects (apnea, bronchodilation) |
| 12 | Other Effects (antiemetic, MH safety, infection risk, pain on injection) |
| 13 | Side Effects & Safety (PRIS, egg allergy, FDA warning) |
| 14 | Contraindications & Precautions |
| 15 | Dosing in Special Populations Table (elderly, children, pregnancy, obesity, organ impairment) |
| 16 | Propofol Infusion Syndrome (PRIS) — full breakdown |
| 17 | Clinical Uses (OR, ICU, ED, ECT, PONV) |
| 18 | Target-Controlled Infusion (TCI) — Marsh & Schnider models, effect-site targets |
| 19 | Fospropofol (Lusedra) |
| 20 | Key Clinical Takeaways (summary) |