Presentation on propofol with full details and all the doses

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Propofol Complete Reference

Presentation · PPTX


What's inside (20 slides)

#Slide
1Title slide
2Overview & Formulation
3Mechanism of Action (GABA-A, NMDA, ion channels)
4Pharmacokinetics (distribution, clearance, metabolism)
5PK Model & Drug Interactions (midazolam, alfentanil, CYP3A4)
6Doses — Quick Reference Table (all indications)
7Induction — Detailed Dosing (adults, elderly, children)
8Maintenance — TIVA & Sedation Dosing
9CNS Effects (BIS targets, ICP, anticonvulsant, EEG)
10Cardiovascular Effects (two-column)
11Respiratory Effects (apnea, bronchodilation)
12Other Effects (antiemetic, MH safety, infection risk, pain on injection)
13Side Effects & Safety (PRIS, egg allergy, FDA warning)
14Contraindications & Precautions
15Dosing in Special Populations Table (elderly, children, pregnancy, obesity, organ impairment)
16Propofol Infusion Syndrome (PRIS) — full breakdown
17Clinical Uses (OR, ICU, ED, ECT, PONV)
18Target-Controlled Infusion (TCI) — Marsh & Schnider models, effect-site targets
19Fospropofol (Lusedra)
20Key Clinical Takeaways (summary)
Design: Navy/teal/sky colour palette, top header bar, left accent stripe, alternating-row tables. All dose data sourced from Miller's Anesthesia 10e and Morgan & Mikhail's Clinical Anesthesiology 7e.
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