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Dynapar (Diclofenac Sodium 75 mg Injection) in a Lactating Mother
Dynaper / Dynapar AQ is Diclofenac Sodium 75 mg IM injection - an NSAID made by Troikaa Pharmaceuticals.
Is it safe for a breastfeeding mother of a 3-month-old?
Generally yes, with caution - it is considered acceptable for short-term use.
Here is what the evidence shows:
Transfer into breast milk is minimal:
- In 6 lactating women given a single 75 mg IM dose, diclofenac was undetectable in breast milk over 6 hours (detection limit 100 mcg/L).
- In another study, 6 mothers given oral diclofenac 100 mg/day for 1 week postpartum had drug levels undetectable (<10 mcg/L) in 59 milk samples.
- The LactMed database (NIH/NCBI) states: "Most reviewers consider diclofenac to be acceptable during breastfeeding."
- Infant relative dose is well under 1% of the weight-adjusted maternal dose - far below the 10% safety threshold.
Why it is relatively safe:
- Diclofenac has a short half-life (~1-2 hours)
- It is highly protein-bound (>99%), limiting transfer to milk
- It undergoes significant first-pass metabolism, further reducing infant exposure
Important Considerations
| Factor | Detail |
|---|
| Age of baby | A 3-month-old is more mature than a newborn - less risk than in the first weeks of life |
| Duration | Keep it to short-term use only (1-3 days). Avoid prolonged courses |
| Dose | Single or few doses of 75 mg IM is acceptable |
| Preferred alternatives | Ibuprofen and paracetamol (acetaminophen) have more safety data and are generally the first-line choices in lactating mothers |
| Watch for in baby | Though extremely unlikely at these milk levels, theoretically watch for GI irritability or unusual drowsiness |
| Contraindication | Avoid if the baby has any known renal issues or if the mother has peptic ulcer disease, renal impairment, or aspirin hypersensitivity |
Bottom Line
A single or short-course IM injection of Dynapar (diclofenac 75 mg) for severe back pain in a lactating mother of a 3-month-old baby is generally considered acceptable based on current evidence. The drug barely enters breast milk and no adverse infant effects have been documented.
However, ibuprofen is the preferred NSAID during breastfeeding because it has the most published safety data. If the back pain is musculoskeletal, a combination of ibuprofen + paracetamol is the standard first-line approach. Dynapar IM may be justified when oral NSAIDs are insufficient or when rapid parenteral relief is needed.
Always advise the mother to breastfeed just before the injection dose to maximize the clearance interval before the next feed.
Note: This is for clinical information purposes. The prescribing physician should make the final decision based on the full clinical picture.