Clinical anatomy of upper limb

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“Clinical anatomy of the upper limb” is a large topic. It can be organized as:
  1. Osteology and surface landmarks
  2. Pectoral region, axilla, and brachial plexus
  3. Shoulder and scapular region
  4. Arm and cubital fossa
  5. Forearm compartments, wrist, and hand
  6. Arteries, veins, lymphatics, and dermatomes
  7. Nerve lesions, common entrapments, and clinical tests
  8. Joints, movements, and applied anatomy
At a high level, the upper limb is designed to position the hand in space. Its clinical anatomy centers on the brachial plexus, the axillary-brachial-radial/ulnar arterial pathway, compartmental muscle actions, and predictable nerve-injury patterns such as wrist drop, clawing, winged scapula, and median-nerve thenar weakness.
Asking for Preferences

Which section should I cover in detail first?

“Clinical anatomy of the upper limb” is a large topic. It can be organized as:
  1. Osteology and surface landmarks
  2. Pectoral region, axilla, and brachial plexus
  3. Shoulder and scapular region
  4. Arm and cubital fossa
  5. Forearm compartments, wrist, and hand
  6. Arteries, veins, lymphatics, and dermatomes
  7. Nerve lesions, common entrapments, and clinical tests
  8. Joints, movements, and applied anatomy
At a high level, the upper limb is designed to position the hand in space. Its clinical anatomy centers on the brachial plexus, the axillary-brachial-radial/ulnar arterial pathway, compartmental muscle actions, and predictable nerve-injury patterns such as wrist drop, clawing, winged scapula, and median-nerve thenar weakness.Which section would you like in detail?
  1. Brachial plexus
  2. Axilla and shoulder
  3. Arm and cubital fossa
  4. Forearm, wrist, and hand
  5. Nerve lesions and clinical tests
  6. Full exam-oriented revision map

Clincal anatomy of upper limb

This is a broad, exam-sized topic. A clinical approach links regional anatomy with common injuries, compression syndromes, examination findings, and procedures.
Asking for Preferences

Which part should I develop first?

“Clinical anatomy of the upper limb” is a large topic. It can be organized as:
  1. Osteology and surface landmarks
  2. Pectoral region, axilla, and brachial plexus
  3. Shoulder and scapular region
  4. Arm and cubital fossa
  5. Forearm compartments, wrist, and hand
  6. Arteries, veins, lymphatics, and dermatomes
  7. Nerve lesions, common entrapments, and clinical tests
  8. Joints, movements, and applied anatomy
At a high level, the upper limb is designed to position the hand in space. Its clinical anatomy centers on the brachial plexus, the axillary-brachial-radial/ulnar arterial pathway, compartmental muscle actions, and predictable nerve-injury patterns such as wrist drop, clawing, winged scapula, and median-nerve thenar weakness.Which section would you like in detail?
  1. Brachial plexus
  2. Axilla and shoulder
  3. Arm and cubital fossa
  4. Forearm, wrist, and hand
  5. Nerve lesions and clinical tests
  6. Full exam-oriented revision mapThis is a broad, exam-sized topic. A clinical approach links regional anatomy with common injuries, compression syndromes, examination findings, and procedures.## Clinical anatomy of the upper limb: topic map
  7. Bones, joints, and surface anatomy
    • Clavicle, scapula, humerus, radius, ulna, carpal bones
    • Shoulder, elbow, wrist, and hand joints
    • Palpable landmarks and common fractures/dislocations
  8. Pectoral region and axilla
    • Pectoral muscles and axillary walls
    • Axillary artery and its branches
    • Axillary vein and lymph nodes
    • Relation to breast surgery and axillary nerve injury
  9. Brachial plexus
    • Roots, trunks, divisions, cords, terminal branches
    • Erb palsy, Klumpke palsy, thoracic outlet compression
    • Important branches: long thoracic, dorsal scapular, suprascapular nerves
  10. Shoulder and scapular region
    • Rotator cuff and movements of the shoulder
    • Glenohumeral dislocation
    • Axillary nerve injury, winged scapula, rotator-cuff tear
  11. Arm and cubital fossa
    • Anterior and posterior compartments
    • Brachial artery, median nerve, radial nerve
    • Biceps tendon, venepuncture, brachial pulse
    • Supracondylar fracture and Volkmann ischemic contracture
  12. Forearm, wrist, and hand
    • Flexor and extensor compartments
    • Radial and ulnar arteries
    • Carpal tunnel, anatomical snuffbox, flexor retinaculum
    • Palmar spaces and tendon sheaths
  13. Peripheral nerve lesions
    • Median nerve: carpal tunnel syndrome, thenar wasting, hand of benediction
    • Ulnar nerve: claw hand, Froment sign
    • Radial nerve: wrist drop
    • Musculocutaneous and axillary nerve lesions
  14. Vessels, veins, lymphatics, and dermatomes
    • Axillary to brachial to radial/ulnar arterial pathway
    • Superficial veins: cephalic, basilic, median cubital
    • Lymphatic drainage to axillary nodes
    • Dermatomes and cutaneous nerve territories
  15. Applied anatomy and examination
    • Motor and sensory testing of major nerves
    • Peripheral pulses and Allen test
    • Common fractures, dislocations, entrapment neuropathies, and compartment syndrome

Core clinical idea

The major examination framework is to identify the site of lesion from the pattern of weakness, sensory loss, vascular impairment, and deformity. For example:
  • Surgical-neck humeral fracture or anterior shoulder dislocation can injure the axillary nerve.
  • Midshaft humeral fracture can injure the radial nerve, causing wrist drop.
  • Supracondylar humeral fracture can endanger the brachial artery and median nerve.
  • Medial epicondyle injury or cubital tunnel compression can affect the ulnar nerve.
  • Carpal tunnel syndrome compresses the median nerve at the wrist.
Reply with a number, such as 3 for brachial plexus or 7 for nerve lesions, and I will give a detailed exam-oriented note on that section.

Create a table of upper-limb nerve injuries

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upper extremity nerve injury

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upper limb peripheral nerve injury examination median ulnar radial axillary clinical findings

Upper-limb nerve injuries: clinical table

NerveCommon site / cause of injuryMain motor deficitCharacteristic clinical signKey sensory lossUseful examination test
Long thoracic nerve (C5-C7)Axillary surgery, trauma to lateral thoracic wall, tractionParalysis of serratus anteriorWinged scapula; difficulty elevating arm above horizontal because scapula cannot rotate upward properlyNoneAsk patient to push against a wall. Medial border of scapula protrudes posteriorly.
Suprascapular nerve (C5-C6)Suprascapular notch compression, traction, shoulder traumaWeak initiation of abduction from 0-15 degrees due to supraspinatus; weak lateral rotation due to infraspinatusWeak shoulder abduction and external rotation; possible supraspinatus/infraspinatus wastingUsually noneTest initiation of abduction and resisted external rotation.
Axillary nerve (C5-C6)Anterior shoulder dislocation; fracture at surgical neck of humerus; deltoid-splitting proceduresDeltoid and teres minor paralysisFlattened shoulder contour; weak abduction from 15-90 degrees and weak external rotation“Regimental badge” area: lateral upper arm over lower deltoidTest deltoid contraction during resisted abduction; assess sensation over lateral shoulder.
Musculocutaneous nerve (C5-C7)Rare isolated injury; upper brachial plexus trauma; penetrating arm injuryWeak elbow flexion and forearm supination due to biceps and brachialis weaknessReduced biceps bulk and weak flexion, especially with forearm supinatedLateral aspect of forearm via lateral cutaneous nerve of forearmTest elbow flexion and supination against resistance; biceps reflex may be reduced.
Radial nerve, proximal lesion (C5-T1)Axillary compression from crutches or prolonged pressure, “Saturday-night palsy”Loss of elbow, wrist, finger, and thumb extension, depending on levelWrist drop; impaired grip because wrist cannot be stabilized in extensionPosterior arm/forearm and dorsolateral hand, especially dorsal first web spaceAsk patient to extend wrist and MCP joints. Test sensation in first dorsal web space.
Radial nerve in spiral grooveMidshaft humeral fractureWrist and finger extension weak or absent, but triceps often sparedWrist drop with preserved or relatively spared elbow extensionDorsal first web space, variable posterior forearm lossTest wrist and finger extension; examine for associated humeral fracture.
Posterior interosseous nerve (deep radial branch)Compression at supinator, radial-head injury, repetitive pronation-supinationFinger and thumb extension weak; wrist extension usually preserved but may deviate radiallyFinger drop without objective sensory lossNone, because it is primarily motorAsk patient to extend MCP joints and thumb.
Superficial radial nerveTight wristwear, distal forearm trauma, compressionNo motor weaknessPainful paresthesia over dorsoradial handDorsolateral hand, particularly dorsal first web spaceSensory examination only; motor extension is intact.
Median nerve, high lesion (at elbow/proximal forearm)Supracondylar fracture, elbow dislocation, proximal forearm laceration, pronator teres compressionWeak pronation; loss of flexion of thumb, index and middle fingers; weak thumb oppositionOn making a fist, index and middle fingers fail to flex: hand of benediction. Thenar wasting may occur.Lateral palm and palmar lateral 3½ digits; dorsal tips of these digitsAsk patient to make a fist, oppose thumb to little finger, and pronate forearm. Test sensation at index-finger pulp.
Anterior interosseous nerve (median branch)Entrapment or forearm traumaFlexor pollicis longus, pronator quadratus, and lateral FDP weaknessAbnormal pinch/OK sign: pad-to-pad pinch instead of a round “O”NoneAsk patient to make an “OK” sign using thumb and index finger.
Median nerve at wristCarpal tunnel syndrome; wrist lacerationThenar weakness, especially abductor pollicis brevis and opponens pollicisThenar wasting; weak opposition, impaired precision grip; “ape thumb” posture in severe chronic lesionPalmar lateral 3½ digits. Thenar eminence sensation is usually spared in carpal tunnel syndrome.Tinel sign at carpal tunnel; Phalen test; test thumb abduction/opposition.
Ulnar nerve, high lesion (at elbow)Medial epicondyle fracture, cubital tunnel compression, elbow dislocationInterossei, medial lumbricals, hypothenar muscles, adductor pollicis, FCU, and medial FDP weaknessWeak finger abduction/adduction, weak grip, impaired flexion of DIP joints of ring/little fingers; clawing is often less marked than in a wrist lesionMedial 1½ digits and adjacent medial hand, palmar and dorsal surfacesAsk patient to abduct/adduct fingers; test Froment sign by having them hold paper between thumb and index finger.
Ulnar nerve at wristLaceration near Guyon canal; cyclist’s palsy; hook of hamate injuryIntrinsic hand-muscle paralysis but FDP preservedUlnar claw is prominent: hyperextension at MCP and flexion at IP joints of ring and little fingers. Hypothenar/interosseous wasting.Palmar medial 1½ digits; dorsal ulnar hand may be spared if dorsal cutaneous branch is intactTest finger abduction/adduction and Froment sign. Compare clawing with high lesion: “ulnar paradox.”
Lower trunk brachial plexus (C8-T1)Traction on an abducted arm, cervical rib or thoracic outlet pathologyWeak intrinsic hand muscles, often with median and ulnar distribution involvementKlumpke palsy: intrinsic-hand weakness and clawed hand; may coexist with Horner syndrome if T1 sympathetic fibers involvedMedial forearm and handExamine intrinsic hand muscles, sensory loss in C8-T1 distribution, and look for ptosis/miosis if severe.
Upper trunk brachial plexus (C5-C6)Birth injury, fall/traction separating head and shoulderWeak shoulder abduction and lateral rotation; weak elbow flexion and supinationErb palsy: “waiter’s tip” posture, with adducted and medially rotated arm, extended elbow, and pronated forearmLateral arm and forearm may be affectedTest deltoid, supraspinatus, biceps, and brachioradialis; biceps reflex may be reduced.

High-yield sensory points

  • Axillary nerve: skin over lower deltoid, “regimental badge” region.
  • Median nerve: palmar tip of index finger.
  • Ulnar nerve: tip of little finger.
  • Radial nerve: dorsal first web space between thumb and index finger.
  • Musculocutaneous nerve: lateral forearm.

High-yield fracture and nerve associations

InjuryNerve most at riskTypical finding
Surgical-neck humeral fracture / anterior shoulder dislocationAxillary nerveDeltoid weakness and sensory loss over lateral shoulder
Midshaft humeral fractureRadial nerveWrist drop
Supracondylar humeral fractureMedian nerve and brachial arteryWeak median-innervated muscles; possible forearm ischemia
Medial epicondyle fractureUlnar nerveInterosseous weakness and ulnar sensory loss
Scaphoid fractureSuperficial radial nerve is not typically injured, but the radial artery is clinically relevantAnatomical snuffbox tenderness
Hook of hamate fractureUlnar nerve in Guyon canalUlnar intrinsic-hand weakness/sensory symptoms
The five terminal branches of the brachial plexus are musculocutaneous, axillary, radial, median, and ulnar nerves, as summarized in the THIEME Atlas of General Anatomy and Musculoskeletal System. For clinical sensory and motor patterns, see the NCBI overview of median nerve injury and the ulnar nerve clinical anatomy review.
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