I have taken 75 gms of glucose at 7:50am lab people gave me 75mg of glucose after first blood test and told me don't eat anything for 2 hrs then we will take another sample. But I am having epigastric pain can I take ppi
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Quick Answer: You are currently doing an Oral Glucose Tolerance Test (OGTT). Taking a PPI (like omeprazole or pantoprazole) during the fasting/waiting window is generally considered acceptable since PPIs are not known to significantly affect blood glucose levels. However, the safest thing is to inform your lab technician or the doctor who ordered the test before taking anything - they can confirm whether it will interfere with your specific test.
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can you take PPI proton pump inhibitor during OGTT oral glucose tolerance test fasting period
Here is a clear answer to your situation:
Your Situation: OGTT in Progress
You have had your fasting blood draw and consumed the 75g glucose load at 7:50 AM. You are now waiting for the 2-hour post-load blood sample (due around 9:50 AM). You are experiencing epigastric pain and want to know if you can take a PPI (like omeprazole or pantoprazole).
Can You Take a PPI During the OGTT Wait?
The short answer: PPIs are unlikely to affect your OGTT result, but you should still inform or ask your lab technician or doctor before taking anything.
Here is the reasoning:
What research says about PPIs and blood glucose:
A published cross-sectional study specifically looked at PPI use and OGTT results in patients undergoing a 75g OGTT. It found no significant association between PPI use and fasting or 2-hour post-load glucose levels - meaning PPIs did not meaningfully alter OGTT results. (International Journal of Medical Sciences study on PPIs and OGTT)
Why it matters to still ask:
- Standard OGTT instructions say do not eat, drink (except water), or take medications during the test window, unless specifically cleared by your doctor.
- Most guidelines (HealthLink BC, Cleveland Clinic, MedlinePlus) recommend telling your doctor about all medications and following their specific instructions.
- Some drugs can affect glucose metabolism - but PPIs (omeprazole, pantoprazole, rabeprazole) are not among the known interfering drugs for OGTT.
Practical Advice
- Call or walk up to the lab technician / phlebotomist right now and tell them you have epigastric pain. Ask if you can take a PPI - they may clear it immediately.
- If you cannot reach anyone, taking a single dose of a standard PPI (e.g., pantoprazole 40mg or omeprazole 20mg) is very unlikely to falsify your glucose result based on current evidence.
- Do not eat or drink anything other than water - this is more important for the test accuracy than the PPI question.
- Avoid antacids with large amounts of sugar or glucose in them (like some liquid antacid suspensions) - plain PPIs are fine.
Important Note
The epigastric pain itself may be related to the glucose load - some people feel nausea, bloating, or stomach discomfort after drinking the glucose solution. This typically eases on its own within 30-60 minutes. If the pain is severe, worsening, or associated with vomiting, inform the lab staff immediately, as vomiting can invalidate the test.
This is general medical information, not a substitute for advice from your treating doctor or the lab staff present with you. Please inform them before taking any medication during the test.
I took 1 hrs sample at home and it is 177 what does that mean
A 1-hour glucose reading of 177 mg/dL after the 75g glucose load is elevated but not definitively diagnostic on its own - the 2-hour value is what matters most for standard OGTT interpretation.
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OGTT 75g 1 hour glucose 177 mg/dL interpretation normal range diagnostic criteria
Here is what your 1-hour reading of 177 mg/dL means:
1-Hour OGTT Result: 177 mg/dL
For a Standard (Non-Pregnancy) Diabetes Screening OGTT:
The 1-hour value is not used for diagnosis in a standard non-pregnant OGTT. Per MedlinePlus / ADA guidelines, the reference cutoffs for the 75g OGTT are:
| Timepoint | Normal | Prediabetes | Diabetes |
|---|---|---|---|
| Fasting | < 100 mg/dL | 100-125 mg/dL | ≥ 126 mg/dL |
| 1 hour | < 200 mg/dL | (not used for diagnosis) | ≥ 200 mg/dL |
| 2 hours | < 140 mg/dL | 140-199 mg/dL | ≥ 200 mg/dL |
Your 1-hour value of 177 mg/dL is below the 200 mg/dL cutoff - so it is within the acceptable range at the 1-hour mark for a non-pregnant diabetes test. The diagnosis depends almost entirely on your 2-hour value.
If This is a Pregnancy (GDM) Test:
If you are pregnant and this is a gestational diabetes screen, the thresholds are stricter. Per IADPSG/ADA criteria:
| Timepoint | GDM Cutoff |
|---|---|
| Fasting | ≥ 92 mg/dL |
| 1 hour | ≥ 180 mg/dL |
| 2 hours | ≥ 153 mg/dL |
Your 1-hour value of 177 mg/dL is below the 180 mg/dL GDM cutoff as well - so it would still be considered normal at this timepoint for GDM screening too.
Bottom Line
- At 1 hour, 177 mg/dL is acceptable under both standard and pregnancy OGTT criteria.
- Your glucose is rising as expected after the load - a reading of 177 at 1 hour is normal physiology.
- The 2-hour value is the one that matters most. Wait for your 2-hour sample (around 9:50 AM) - if it comes back below 140 mg/dL, everything is normal. If it is 140-199, that indicates prediabetes/impaired glucose tolerance, and ≥200 would indicate diabetes.
- Do not eat, exercise, or smoke until that 2-hour sample is taken.
Your 1-hour result of 177 is not alarming. Focus on completing the 2-hour draw properly.
So what are recomme ded 2 hrs values for non pregnant women
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