Orris

can lipoprotein a rise more than 90 in a person without genetics

Short answer: usually no.
A large increase in Lipoprotein(a), such as >90 mg/dL (or roughly >200 nmol/L depending on assay), is most often genetic. Lp(a) is largely determined by the LPA gene and tends to stay fairly stable through life.
What can happen without genetics:
  • Small to moderate fluctuations from lab variability or physiologic states
  • Temporary increases with inflammation, kidney disease, hypothyroidism, menopause, etc.
  • Measurement differences between labs (mg/dL vs nmol/L, isoform effects)
But a true persistent level above 90 is generally considered genetically driven, even if there is no known family history.
If this was a new unexpected result, useful next steps are:
  1. Repeat the test once (same units, ideally same lab)
  2. Check for secondary factors (thyroid, kidney disease, acute illness/inflammation)
  3. Review cardiovascular risk with a clinician
If you want, I can help interpret your exact Lp(a) value and units (mg/dL vs nmol/L).
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