Create an Anki card for [Mediators of inflammation, just a short introduction. Next heading should be cell-derived mediators, and that heading should be blank. Next should be newly synthesized mediators. First is platelet activating factor, its sources and functions. Second is nitric oxide, its physical characteristics, sources, and functions. Third is cytokines, its source and types, along with functions. Next is chemokines. Keep chemokines blank. Next is arachidonic acid metabolites. Next is class-derived mediators, the complement system, the complement cascade, pathways, and the kinin system. ] for NEET PG 2027 exam (pathology focus). Output a downloadable .txt file with exactly one line in this format: Front[TAB]Back. The Front should contain only the topic name. The Back should contain a comprehensive summary covering 100% of exam-relevant content, formatted using HTML bold tags for section headings and <br><br> between sections for spacing and readability. Do not use any newlines, pipes, or semicolons in the file — only commas, colons, dashes, and HTML tags. Confirm the file is exactly 1 line using wc -l before delivering it.
wc -l confirms exactly 1 line. The file is ready.mediators of inflammation
Text File · TXT
wc -l = 1).Mediators of Inflammation| Section | Content |
|---|---|
| Introduction | Definition, cell-derived vs plasma-derived mediators, short life, redundancy |
| Cell-Derived Mediators | (blank as requested) |
| Newly Synthesized Mediators | Header |
| 1. PAF | Phospholipid mediator - sources (platelets, basophils, mast cells, neutrophils, macrophages, endothelium) - functions (platelet aggregation, vasoconstriction, bronchoconstriction, vasodilation, increased permeability, leukocyte adhesion, chemotaxis, oxidative burst) |
| 2. Nitric Oxide | Soluble gas - 3 NOS isoforms (eNOS/nNOS/iNOS) - sources - functions (microbicidal via peroxynitrite, vasodilation, neurotransmitter) |
| 3. Cytokines | Sources - TNF, IL-1, IL-6, IL-17, IL-12, IFN-gamma - mechanisms - systemic effects - therapeutic relevance |
| Chemokines | (blank as requested) |
| Arachidonic Acid Metabolites | Full COX/LOX pathways - PGs (PGE2, PGD2, PGI2, TxA2) - Leukotrienes (LTB4, LTC4/D4/E4) - Lipoxins - NSAIDs, COX-2 inhibitors, corticosteroids |
| Complement System | 20+ proteins - 3 pathways (classical/alternative/lectin) - cascade (C3 convertase, C5 convertase, MAC) - functions (inflammation, opsonization, lysis) - regulatory proteins (C1INH, DAF, CD59, Factor H) - associated diseases |
| Kinin System | Kallikrein - HMW kininogen - Bradykinin - functions (vascular permeability, pain, smooth muscle contraction, vasodilation) - kininase inactivation - link to Factor XII |