🎯 ULTIMATE INTEGRATED NEET PG MASTER CURRICULUM

from reportlab.lib.pagesizes import A4
from reportlab.lib.styles import getSampleStyleSheet, ParagraphStyle
from reportlab.lib.units import cm, mm
from reportlab.lib.colors import HexColor, white, black
from reportlab.platypus import (
    SimpleDocTemplate, Paragraph, Spacer, Table, TableStyle,
    PageBreak, HRFlowable, KeepTogether
)
from reportlab.lib.enums import TA_CENTER, TA_LEFT, TA_JUSTIFY
from reportlab.platypus import BaseDocTemplate, Frame, PageTemplate
from reportlab.lib import colors
import os

OUTPUT_PATH = "/home/daytona/workspace/neet-pg-curriculum/NEET_PG_Master_Curriculum.pdf"

# ── Colour Palette ──────────────────────────────────────────────────────────
DARK_BLUE   = HexColor("#0D1B2A")
MID_BLUE    = HexColor("#1B4F72")
ACCENT_BLUE = HexColor("#2E86C1")
LIGHT_BLUE  = HexColor("#D6EAF8")
ORANGE      = HexColor("#E67E22")
GREEN       = HexColor("#1E8449")
LIGHT_GREEN = HexColor("#D5F5E3")
PURPLE      = HexColor("#6C3483")
LIGHT_PURPLE= HexColor("#E8DAEF")
RED         = HexColor("#C0392B")
LIGHT_RED   = HexColor("#FDEDEC")
YELLOW_BG   = HexColor("#FEF9E7")
GREY_BG     = HexColor("#F2F3F4")
GREY_BORDER = HexColor("#BDC3C7")

W, H = A4

# ── Styles ───────────────────────────────────────────────────────────────────
styles = getSampleStyleSheet()

def S(name, **kw):
    return ParagraphStyle(name, **kw)

cover_title = S("CoverTitle",
    fontSize=28, leading=34, textColor=white,
    fontName="Helvetica-Bold", alignment=TA_CENTER, spaceAfter=10)

cover_sub = S("CoverSub",
    fontSize=14, leading=18, textColor=HexColor("#D6EAF8"),
    fontName="Helvetica", alignment=TA_CENTER, spaceAfter=6)

cover_tag = S("CoverTag",
    fontSize=11, leading=15, textColor=HexColor("#F9E79F"),
    fontName="Helvetica-Oblique", alignment=TA_CENTER)

phase_heading = S("PhaseHeading",
    fontSize=16, leading=20, textColor=white,
    fontName="Helvetica-Bold", alignment=TA_LEFT,
    spaceBefore=18, spaceAfter=6,
    backColor=DARK_BLUE,
    leftIndent=0, borderPad=8)

module_heading = S("ModuleHeading",
    fontSize=13, leading=17, textColor=white,
    fontName="Helvetica-Bold", alignment=TA_LEFT,
    spaceBefore=10, spaceAfter=4,
    backColor=MID_BLUE,
    leftIndent=0)

topic_style = S("TopicStyle",
    fontSize=9.5, leading=13, textColor=HexColor("#1A1A2E"),
    fontName="Helvetica", leftIndent=12, spaceAfter=2)

topic_bold = S("TopicBold",
    fontSize=9.5, leading=13, textColor=HexColor("#154360"),
    fontName="Helvetica-Bold", leftIndent=12, spaceAfter=2)

section_note = S("SectionNote",
    fontSize=8.5, leading=12, textColor=HexColor("#555555"),
    fontName="Helvetica-Oblique", leftIndent=12, spaceAfter=4)

box_title = S("BoxTitle",
    fontSize=10, leading=13, textColor=DARK_BLUE,
    fontName="Helvetica-Bold", alignment=TA_CENTER)

box_body = S("BoxBody",
    fontSize=9, leading=13, textColor=HexColor("#1A1A2E"),
    fontName="Helvetica", alignment=TA_LEFT)

footer_style = S("FooterStyle",
    fontSize=8, textColor=HexColor("#999999"),
    fontName="Helvetica", alignment=TA_CENTER)

toc_phase = S("TOCPhase",
    fontSize=11, leading=15, textColor=MID_BLUE,
    fontName="Helvetica-Bold", leftIndent=0, spaceAfter=2)

toc_item = S("TOCItem",
    fontSize=9, leading=13, textColor=HexColor("#333333"),
    fontName="Helvetica", leftIndent=16, spaceAfter=1)

rule_style = S("RuleStyle",
    fontSize=9, leading=13, textColor=HexColor("#333333"),
    fontName="Helvetica", leftIndent=8, spaceAfter=2)

page_title = S("PageTitle",
    fontSize=14, leading=18, textColor=DARK_BLUE,
    fontName="Helvetica-Bold", alignment=TA_CENTER,
    spaceBefore=0, spaceAfter=12)

# ── Header / Footer callbacks ────────────────────────────────────────────────
def header_footer(canvas, doc):
    canvas.saveState()
    # Header bar
    canvas.setFillColor(DARK_BLUE)
    canvas.rect(0, H - 28, W, 28, fill=1, stroke=0)
    canvas.setFillColor(white)
    canvas.setFont("Helvetica-Bold", 9)
    canvas.drawString(1.5*cm, H - 20, "ULTIMATE INTEGRATED NEET PG MASTER CURRICULUM")
    canvas.setFont("Helvetica", 8)
    canvas.drawRightString(W - 1.5*cm, H - 20, "Your Personal NEET PG Mentor")
    # Footer bar
    canvas.setFillColor(DARK_BLUE)
    canvas.rect(0, 0, W, 22, fill=1, stroke=0)
    canvas.setFillColor(HexColor("#AAAAAA"))
    canvas.setFont("Helvetica", 8)
    canvas.drawString(1.5*cm, 7, "Prepared for NEET PG 2026-27  |  All rights reserved")
    canvas.setFillColor(white)
    canvas.setFont("Helvetica-Bold", 9)
    canvas.drawRightString(W - 1.5*cm, 7, f"Page {doc.page}")
    canvas.restoreState()

def cover_page_cb(canvas, doc):
    canvas.saveState()
    # Full page gradient-like background
    canvas.setFillColor(DARK_BLUE)
    canvas.rect(0, 0, W, H, fill=1, stroke=0)
    # Decorative top stripe
    canvas.setFillColor(ACCENT_BLUE)
    canvas.rect(0, H - 6*mm, W, 6*mm, fill=1, stroke=0)
    # Decorative bottom stripe
    canvas.setFillColor(ORANGE)
    canvas.rect(0, 0, W, 6*mm, fill=1, stroke=0)
    # Faint large background text watermark
    canvas.setFillColor(HexColor("#1A3A5C"))
    canvas.setFont("Helvetica-Bold", 120)
    canvas.saveState()
    canvas.translate(W/2, H/2)
    canvas.rotate(30)
    canvas.drawCentredString(0, 0, "NEET PG")
    canvas.restoreState()
    canvas.restoreState()

# ── Helper: coloured section block ──────────────────────────────────────────
def phase_block(title):
    data = [[Paragraph(f"  {title}", phase_heading)]]
    t = Table(data, colWidths=[W - 3*cm])
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,-1), DARK_BLUE),
        ("TOPPADDING",  (0,0), (-1,-1), 8),
        ("BOTTOMPADDING",(0,0),(-1,-1), 8),
        ("LEFTPADDING", (0,0), (-1,-1), 10),
        ("RIGHTPADDING",(0,0), (-1,-1), 10),
        ("ROUNDEDCORNERS", [4]),
    ]))
    return t

def module_block(title, color=MID_BLUE):
    data = [[Paragraph(f"  {title}", module_heading)]]
    t = Table(data, colWidths=[W - 3*cm])
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,-1), color),
        ("TOPPADDING",  (0,0), (-1,-1), 5),
        ("BOTTOMPADDING",(0,0),(-1,-1), 5),
        ("LEFTPADDING", (0,0), (-1,-1), 10),
        ("RIGHTPADDING",(0,0), (-1,-1), 10),
    ]))
    return t

def topic(num, text, bold=False):
    st = topic_bold if bold else topic_style
    return Paragraph(f"<b>{num}.</b>  {text}", st)

def note(text):
    return Paragraph(f"<i>{text}</i>", section_note)

def sp(n=6):
    return Spacer(1, n)

def hr(color=GREY_BORDER):
    return HRFlowable(width="100%", thickness=0.5, color=color, spaceAfter=4, spaceBefore=4)

# ── INFO BOX helper ──────────────────────────────────────────────────────────
def info_box(title, items, bg=LIGHT_BLUE, title_color=MID_BLUE):
    rows = [[Paragraph(title, S("IB_T", fontSize=10, fontName="Helvetica-Bold",
                                 textColor=title_color, leading=13))]]
    for it in items:
        rows.append([Paragraph(f"• {it}", S("IB_B", fontSize=8.5, fontName="Helvetica",
                                             textColor=DARK_BLUE, leading=12, leftIndent=6))])
    t = Table(rows, colWidths=[W - 3*cm])
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (0,0), bg),
        ("BACKGROUND", (0,1), (-1,-1), HexColor("#FAFCFF")),
        ("BOX", (0,0), (-1,-1), 0.8, title_color),
        ("LINEBELOW", (0,0), (0,0), 0.5, title_color),
        ("TOPPADDING",  (0,0), (-1,-1), 5),
        ("BOTTOMPADDING",(0,0),(-1,-1), 4),
        ("LEFTPADDING", (0,0), (-1,-1), 8),
        ("RIGHTPADDING",(0,0), (-1,-1), 8),
    ]))
    return t

# ── Two-column table helper ──────────────────────────────────────────────────
def two_col_table(left_items, right_items, bg1=LIGHT_BLUE, bg2=LIGHT_GREEN):
    col_w = (W - 3*cm) / 2 - 2*mm

    def cell_para(text, bg):
        return Paragraph(f"• {text}", S("TC", fontSize=8.5, fontName="Helvetica",
                                        textColor=DARK_BLUE, leading=12, leftIndent=4))

    max_rows = max(len(left_items), len(right_items))
    data = []
    for i in range(max_rows):
        l = cell_para(left_items[i], bg1) if i < len(left_items) else Paragraph("", styles["Normal"])
        r = cell_para(right_items[i], bg2) if i < len(right_items) else Paragraph("", styles["Normal"])
        data.append([l, r])

    t = Table(data, colWidths=[col_w, col_w], hAlign="LEFT")
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (0,-1), bg1),
        ("BACKGROUND", (1,0), (1,-1), bg2),
        ("BOX", (0,0), (-1,-1), 0.5, GREY_BORDER),
        ("INNERGRID", (0,0), (-1,-1), 0.3, GREY_BORDER),
        ("TOPPADDING", (0,0), (-1,-1), 4),
        ("BOTTOMPADDING",(0,0),(-1,-1), 3),
        ("LEFTPADDING", (0,0), (-1,-1), 6),
        ("RIGHTPADDING",(0,0),(-1,-1), 6),
    ]))
    return t

# ── SUMMARY TABLE ────────────────────────────────────────────────────────────
def summary_table():
    headers = ["Phase", "Content Area", "Topic Range", "MCQ Weight"]
    rows = [
        ["Phase 1", "Foundations of Life & Disease", "1 – 27",   "~8%"],
        ["Phase 2", "Normal Structure & Function",   "28 – 91",  "~12%"],
        ["Phase 3", "Mechanisms of Disease",         "92 – 115", "~10%"],
        ["Phase 4", "Integrated Clinical Medicine",  "116 – 250","~35%"],
        ["Phase 5", "Surgery",                       "251 – 287","~15%"],
        ["Phase 6", "Specialty Medicine",            "288 – 351","~12%"],
        ["Phase 7", "Community Medicine & Pharma",  "352 – 378","~5%"],
        ["Phase 8", "Forensic Medicine",             "379 – 385","~1%"],
        ["Phase 9", "Integrated Revision",           "386 – 402","~2%"],
    ]
    col_w = [(W-3*cm)*f for f in [0.12, 0.44, 0.22, 0.22]]
    hdr_para = [Paragraph(h, S("TH", fontSize=9, fontName="Helvetica-Bold",
                                 textColor=white, leading=12, alignment=TA_CENTER))
                for h in headers]
    all_rows = [hdr_para]
    for i, row in enumerate(rows):
        bg = LIGHT_BLUE if i % 2 == 0 else white
        all_rows.append([
            Paragraph(row[0], S(f"TR{i}a", fontSize=8.5, fontName="Helvetica-Bold",
                                 textColor=MID_BLUE, leading=12, alignment=TA_CENTER)),
            Paragraph(row[1], S(f"TR{i}b", fontSize=8.5, fontName="Helvetica",
                                 textColor=DARK_BLUE, leading=12)),
            Paragraph(row[2], S(f"TR{i}c", fontSize=8.5, fontName="Helvetica",
                                 textColor=HexColor("#333333"), leading=12, alignment=TA_CENTER)),
            Paragraph(row[3], S(f"TR{i}d", fontSize=8.5, fontName="Helvetica-Bold",
                                 textColor=GREEN, leading=12, alignment=TA_CENTER)),
        ])
    t = Table(all_rows, colWidths=col_w)
    t.setStyle(TableStyle([
        ("BACKGROUND", (0,0), (-1,0), MID_BLUE),
        ("BACKGROUND", (0,1), (-1,1), LIGHT_BLUE),
        ("BACKGROUND", (0,2), (-1,2), white),
        ("BACKGROUND", (0,3), (-1,3), LIGHT_BLUE),
        ("BACKGROUND", (0,4), (-1,4), white),
        ("BACKGROUND", (0,5), (-1,5), LIGHT_BLUE),
        ("BACKGROUND", (0,6), (-1,6), white),
        ("BACKGROUND", (0,7), (-1,7), LIGHT_BLUE),
        ("BACKGROUND", (0,8), (-1,8), white),
        ("BACKGROUND", (0,9), (-1,9), LIGHT_BLUE),
        ("BOX", (0,0), (-1,-1), 1, MID_BLUE),
        ("INNERGRID", (0,0), (-1,-1), 0.3, GREY_BORDER),
        ("TOPPADDING", (0,0), (-1,-1), 5),
        ("BOTTOMPADDING",(0,0),(-1,-1), 5),
        ("LEFTPADDING", (0,0), (-1,-1), 6),
        ("RIGHTPADDING",(0,0),(-1,-1), 6),
        ("ALIGN", (0,0), (-1,-1), "CENTER"),
        ("VALIGN", (0,0), (-1,-1), "MIDDLE"),
        ("ALIGN", (1,1), (1,-1), "LEFT"),
    ]))
    return t

# ── 55-POINT FRAMEWORK TABLE ─────────────────────────────────────────────────
def framework_table():
    points = [
        ("1","Definition"),("2","Importance – NEET PG Perspective"),
        ("3","Epidemiology"),("4","Basic Anatomy"),("5","Embryology"),
        ("6","Histology"),("7","Physiology"),("8","Biochemistry"),
        ("9","Genetics"),("10","Pathogenesis"),("11","Pathology"),
        ("12","Microbiology"),("13","Immunology"),("14","Clinical Features"),
        ("15","Clinical Examination"),("16","Differential Diagnosis"),
        ("17","Investigations"),("18","Radiology"),("19","Histopathology"),
        ("20","Medicine"),("21","Surgery"),("22","Pediatrics"),
        ("23","Obstetrics & Gynecology"),("24","Dermatology Correlation"),
        ("25","Psychiatry Correlation"),("26","Ophthalmology Correlation"),
        ("27","ENT Correlation"),("28","Orthopedics Correlation"),
        ("29","Community Medicine"),("30","Forensic Medicine"),
        ("31","Pharmacology"),("32","Emergency Management"),
        ("33","ICU / Critical Care"),("34","Complications"),("35","Prognosis"),
        ("36","Recent Guidelines"),("37","Procedures / Operations"),
        ("38","Flowcharts"),("39","Algorithms"),("40","Diagnostic Criteria"),
        ("41","Classifications"),("42","Staging / Scoring Systems"),
        ("43","Must-Know Lab Values"),("44","Image-Based NEET Points"),
        ("45","Instruments Used"),("46","High-Yield Tables"),
        ("47","Frequently Confused Concepts"),("48","Common Student Mistakes"),
        ("49","Memory Tricks"),("50","Mnemonics"),
        ("51","Previous NEET PG Pattern"),("52","Clinical Case Discussion"),
        ("53","Integrated MCQs (Easy → Difficult)"),
        ("54","One-Liner Rapid Revision"),("55","Last-Minute Volatile Facts"),
    ]
    col_w = [(W-3*cm)*f for f in [0.07, 0.43, 0.07, 0.43]]
    rows = []
    for i in range(0, len(points), 2):
        p1 = points[i]
        p2 = points[i+1] if i+1 < len(points) else ("", "")
        rows.append([
            Paragraph(p1[0], S(f"FN{i}", fontSize=8.5, fontName="Helvetica-Bold",
                                textColor=ACCENT_BLUE, leading=12, alignment=TA_CENTER)),
            Paragraph(p1[1], S(f"FT{i}", fontSize=8.5, fontName="Helvetica",
                                textColor=DARK_BLUE, leading=12)),
            Paragraph(p2[0], S(f"FN{i}b", fontSize=8.5, fontName="Helvetica-Bold",
                                textColor=ACCENT_BLUE, leading=12, alignment=TA_CENTER)),
            Paragraph(p2[1], S(f"FT{i}b", fontSize=8.5, fontName="Helvetica",
                                textColor=DARK_BLUE, leading=12)),
        ])
    t = Table(rows, colWidths=col_w)
    t.setStyle(TableStyle([
        *[("BACKGROUND", (0,i), (-1,i), LIGHT_BLUE if i%2==0 else white) for i in range(len(rows))],
        ("BOX", (0,0), (-1,-1), 0.8, ACCENT_BLUE),
        ("INNERGRID", (0,0), (-1,-1), 0.3, GREY_BORDER),
        ("LINEAFTER", (1,0), (1,-1), 0.8, ACCENT_BLUE),
        ("TOPPADDING", (0,0), (-1,-1), 4),
        ("BOTTOMPADDING",(0,0),(-1,-1), 4),
        ("LEFTPADDING", (0,0), (-1,-1), 5),
        ("RIGHTPADDING",(0,0),(-1,-1), 5),
        ("VALIGN", (0,0), (-1,-1), "MIDDLE"),
    ]))
    return t

# ════════════════════════════════════════════════════════════════════════════
# BUILD DOCUMENT
# ════════════════════════════════════════════════════════════════════════════
doc = BaseDocTemplate(
    OUTPUT_PATH, pagesize=A4,
    leftMargin=1.5*cm, rightMargin=1.5*cm,
    topMargin=1.8*cm, bottomMargin=1.5*cm,
    title="Ultimate Integrated NEET PG Master Curriculum",
    author="Your Personal NEET PG Mentor",
)

# Frames
content_frame = Frame(
    doc.leftMargin, doc.bottomMargin,
    W - doc.leftMargin - doc.rightMargin,
    H - doc.topMargin - doc.bottomMargin - 28 - 22,  # subtract header+footer
    id="content"
)
cover_frame = Frame(
    1.5*cm, 2*cm, W - 3*cm, H - 4*cm, id="cover"
)

doc.addPageTemplates([
    PageTemplate(id="Cover", frames=[cover_frame], onPage=cover_page_cb),
    PageTemplate(id="Normal", frames=[content_frame], onPage=header_footer),
])

story = []

# ── COVER PAGE ───────────────────────────────────────────────────────────────
story.append(Spacer(1, 3*cm))
story.append(Paragraph("ULTIMATE INTEGRATED", cover_title))
story.append(Paragraph("NEET PG MASTER CURRICULUM", cover_title))
story.append(Spacer(1, 0.5*cm))
story.append(HRFlowable(width="80%", thickness=2, color=ORANGE,
                         spaceAfter=12, spaceBefore=4, hAlign="CENTER"))
story.append(Paragraph("Complete Topic-by-Topic Syllabus", cover_sub))
story.append(Paragraph("Basics → Advanced Clinical Medicine", cover_sub))
story.append(Spacer(1, 0.4*cm))
story.append(Paragraph("Organized Logically — Not Subject-Wise", cover_tag))
story.append(Spacer(1, 1.2*cm))

# Quick stats boxes on cover
stats = [
    ["402+", "Integrated\nTopics"],
    ["9",    "Learning\nPhases"],
    ["45",  "Curriculum\nModules"],
    ["55",   "Points Per\nTopic"],
]
stat_data = [[
    Paragraph(f"<b><font size=22 color='#{\"F39C12\"}'>{s[0]}</font></b><br/>"
              f"<font size=9 color='#AED6F1'>{s[1]}</font>", 
              S(f"ST{i}", fontSize=9, fontName="Helvetica", alignment=TA_CENTER,
                textColor=white, leading=14))
    for i, s in enumerate(stats)
]]
stat_t = Table(stat_data, colWidths=[(W-3*cm)/4]*4)
stat_t.setStyle(TableStyle([
    ("BACKGROUND", (0,0), (-1,-1), HexColor("#1A3A5C")),
    ("BOX", (0,0), (-1,-1), 1, ACCENT_BLUE),
    ("INNERGRID", (0,0), (-1,-1), 0.5, ACCENT_BLUE),
    ("TOPPADDING", (0,0), (-1,-1), 12),
    ("BOTTOMPADDING",(0,0),(-1,-1), 12),
    ("ALIGN", (0,0), (-1,-1), "CENTER"),
    ("VALIGN", (0,0), (-1,-1), "MIDDLE"),
]))
story.append(stat_t)
story.append(Spacer(1, 1*cm))
story.append(HRFlowable(width="60%", thickness=1, color=HexColor("#2E86C1"),
                         spaceAfter=8, spaceBefore=4, hAlign="CENTER"))
story.append(Paragraph("Based on: Robbins • Harrison's • Guyton • Katzung • Bailey & Love • Park's • Ananthanarayan", cover_tag))
story.append(Spacer(1, 0.3*cm))
story.append(Paragraph("NEET PG 2026 – 27  |  Updated June 2026", cover_tag))
story.append(Spacer(1, 1.5*cm))
story.append(Paragraph("Your Personal NEET PG Mentor, Senior Clinician & Integrated MBBS Teacher", 
                        S("CoverFooter", fontSize=10, fontName="Helvetica-Oblique",
                          textColor=HexColor("#85C1E9"), alignment=TA_CENTER)))

story.append(PageBreak())

# Switch to normal template from page 2 onwards
story.append(Paragraph("", S("SwitchTemplate", fontSize=1)))  # placeholder

# ── PAGE 2: HOW TO USE THIS DOCUMENT ─────────────────────────────────────────
from reportlab.platypus import NextPageTemplate
story[-1] = NextPageTemplate("Normal")
story.append(PageBreak())

story.append(Paragraph("HOW TO USE THIS CURRICULUM", page_title))
story.append(hr(ACCENT_BLUE))
story.append(sp(8))

story.append(info_box(
    "The 55-Point Integrated Teaching Framework",
    ["Every single topic in this curriculum is taught using all 55 points below.",
     "This ensures complete MBBS integration — from cell biology to bedside medicine.",
     "Use it for FIRST LEARNING and FINAL REVISION of any topic."],
    bg=LIGHT_BLUE, title_color=MID_BLUE
))
story.append(sp(10))
story.append(framework_table())
story.append(sp(12))

story.append(info_box(
    "Step-by-Step Learning Strategy",
    [
        "Step 1: Start Phase 1 (Foundations) — understand how cells work before diseases occur",
        "Step 2: Phase 2 (Normal Structure & Function) — master normal before learning abnormal",
        "Step 3: Phase 3 (Mechanisms) — inflammation, immunity, infection are the bridges",
        "Step 4: Phases 4–6 are the CORE — ~62% of NEET PG MCQs come from here",
        "Step 5: Phase 7 (Community Medicine & Pharmacology) — high-scoring boosters",
        "Step 6: Phases 8–9 (Forensic + Integrated Revision) — last-mile differentiators",
        "Tip: Each topic connects to previously learned topics — always look backward and forward",
    ],
    bg=LIGHT_GREEN, title_color=GREEN
))
story.append(sp(10))

story.append(Paragraph("Phase-wise MCQ Weightage at a Glance", 
                        S("SubHdr", fontSize=11, fontName="Helvetica-Bold",
                          textColor=DARK_BLUE, leading=15, spaceAfter=6)))
story.append(summary_table())

story.append(PageBreak())

# ── PAGE 3+: CURRICULUM CONTENT ──────────────────────────────────────────────
story.append(Paragraph("COMPLETE CURRICULUM — TOPIC LIST", page_title))
story.append(hr(ACCENT_BLUE))
story.append(sp(4))

# ═══════════════════════════════════════════════════════════
# PHASE 1
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 1 — FOUNDATIONS OF LIFE & DISEASE"))
story.append(note("Cell → Tissue → Organ → System  |  Topics 1–27"))
story.append(sp(6))

story.append(module_block("MODULE 1: The Cell — Structure & Function"))
cell_topics = [
    (1,  "Cell membrane structure & transport mechanisms"),
    (2,  "Nucleus, DNA, RNA — structure and function"),
    (3,  "Cell organelles (Mitochondria, ER, Golgi, Lysosomes, Peroxisomes)"),
    (4,  "Cell cycle — phases, checkpoints, cyclins"),
    (5,  "Apoptosis vs Necrosis"),
    (6,  "Cell signaling — receptors, second messengers, signal transduction"),
    (7,  "Free radicals & oxidative stress — cellular injury"),
]
for n_, t_ in cell_topics:
    story.append(topic(n_, t_))
story.append(sp(6))

story.append(module_block("MODULE 2: Genetics & Molecular Biology"))
gen_topics = [
    (8,  "Mendelian genetics — dominant, recessive, X-linked"),
    (9,  "Chromosomal disorders — Down, Turner, Klinefelter, Edwards, Patau"),
    (10, "Single gene disorders — cystic fibrosis, sickle cell, PKU, Marfan"),
    (11, "Mitochondrial inheritance disorders"),
    (12, "Genomic imprinting — Prader-Willi, Angelman syndromes"),
    (13, "Trinucleotide repeat disorders — Huntington, Fragile X, Myotonic dystrophy"),
    (14, "DNA repair mechanisms & disorders — Xeroderma pigmentosum, BRCA"),
    (15, "Oncogenes, tumor suppressor genes, cancer genetics"),
    (16, "PCR, FISH, karyotyping, gene sequencing — diagnostic techniques"),
]
for n_, t_ in gen_topics:
    story.append(topic(n_, t_))
story.append(sp(6))

story.append(module_block("MODULE 3: Biochemistry Foundations"))
bio_topics = [
    (17, "Carbohydrate metabolism — glycolysis, TCA cycle, gluconeogenesis"),
    (18, "Glycogen metabolism & glycogen storage diseases"),
    (19, "Lipid metabolism — fatty acid synthesis, beta-oxidation, ketone bodies"),
    (20, "Lipoprotein metabolism — HDL, LDL, VLDL, chylomicrons"),
    (21, "Protein & amino acid metabolism — urea cycle, transamination"),
    (22, "Enzyme kinetics — Km, Vmax, inhibitors"),
    (23, "Vitamins — water soluble (B1–B12, C) and fat soluble (A, D, E, K)"),
    (24, "Minerals — iron, calcium, zinc, iodine, fluoride, selenium"),
    (25, "Nucleotide metabolism — purines, pyrimidines, gout"),
    (26, "Heme synthesis & porphyrias"),
    (27, "Bilirubin metabolism — jaundice classification"),
]
for n_, t_ in bio_topics:
    story.append(topic(n_, t_))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 2
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 2 — NORMAL STRUCTURE & FUNCTION"))
story.append(note("Histology → Physiology — Organ by Organ  |  Topics 28–91"))
story.append(sp(6))

modules_phase2 = [
    ("MODULE 4: Blood & Hematopoiesis", MID_BLUE, [
        (28, "Hematopoiesis — sites, growth factors, stem cells"),
        (29, "RBC structure, function, lifespan, destruction"),
        (30, "Hemoglobin — structure, variants, oxygen-dissociation curve"),
        (31, "WBC — types, functions, life cycle"),
        (32, "Platelets — formation, function, aggregation"),
        (33, "Coagulation cascade — intrinsic, extrinsic, common pathway"),
        (34, "Blood groups — ABO, Rh system, transfusion reactions"),
    ]),
    ("MODULE 5: Cardiovascular System", HexColor("#1A5276"), [
        (35, "Heart — anatomy, chambers, valves, conducting system"),
        (36, "Cardiac embryology — development, common congenital defects"),
        (37, "Cardiac histology — myocardium, pericardium"),
        (38, "Cardiac physiology — action potential, cardiac cycle, Frank-Starling"),
        (39, "Blood pressure regulation — RAAS, ANP, baroreceptors"),
        (40, "Electrocardiography (ECG) — normal and abnormal"),
    ]),
    ("MODULE 6: Respiratory System", HexColor("#1E8449"), [
        (41, "Lung anatomy — lobes, segments, pleura"),
        (42, "Respiratory embryology"),
        (43, "Lung histology — type I & II pneumocytes, Clara cells"),
        (44, "Respiratory physiology — ventilation, perfusion, V/Q ratio"),
        (45, "Lung volumes & capacities — spirometry"),
        (46, "Oxygen & CO2 transport"),
        (47, "Acid-base physiology — ABG interpretation"),
    ]),
    ("MODULE 7: Renal System", HexColor("#6C3483"), [
        (48, "Kidney anatomy — gross, microanatomy, juxtaglomerular apparatus"),
        (49, "Renal embryology — pronephros, mesonephros, metanephros"),
        (50, "Renal histology — nephron segments"),
        (51, "Renal physiology — GFR, tubular functions, concentration/dilution"),
        (52, "Renin-angiotensin-aldosterone system (detailed)"),
        (53, "Acid-base regulation by kidneys"),
        (54, "Urinary system — ureters, bladder, urethra"),
    ]),
    ("MODULE 8: Gastrointestinal System", HexColor("#784212"), [
        (55, "GI tract anatomy — from esophagus to rectum"),
        (56, "GI embryology — gut rotation, fixation, common anomalies"),
        (57, "GI histology — layers, specialized cells"),
        (58, "GI physiology — motility, secretion, digestion, absorption"),
        (59, "Liver anatomy & histology — lobule, acinus, sinusoids"),
        (60, "Liver physiology — functions, bile synthesis"),
        (61, "Pancreas — anatomy, histology, exocrine & endocrine function"),
    ]),
    ("MODULE 9: Endocrine System", HexColor("#1A5276"), [
        (62, "Hypothalamus-pituitary axis — anatomy & hormones"),
        (63, "Thyroid gland — anatomy, histology, hormone synthesis"),
        (64, "Adrenal gland — cortex (zones), medulla — hormones"),
        (65, "Parathyroid & calcium regulation"),
        (66, "Pancreatic endocrine — insulin, glucagon physiology"),
        (67, "Gonads — male & female hormones, feedback loops"),
    ]),
    ("MODULE 10: Nervous System", HexColor("#1E8449"), [
        (68, "Neuroembryology — neural tube, neural crest cells"),
        (69, "Brain anatomy — lobes, limbic system, basal ganglia, cerebellum"),
        (70, "Spinal cord anatomy — tracts, segments"),
        (71, "Neurophysiology — resting membrane potential, action potential"),
        (72, "Synapse physiology — neurotransmitters"),
        (73, "Autonomic nervous system — sympathetic, parasympathetic"),
        (74, "Neuromuscular junction — physiology & pharmacology"),
        (75, "CSF — production, circulation, composition"),
        (76, "Blood-brain barrier"),
    ]),
    ("MODULE 11: Musculoskeletal System", HexColor("#6C3483"), [
        (77, "Bone — structure, histology, remodeling, growth plate"),
        (78, "Bone embryology — intramembranous vs endochondral ossification"),
        (79, "Joint types — anatomy & histology"),
        (80, "Muscle histology — skeletal, smooth, cardiac"),
        (81, "Muscle physiology — contraction mechanism, cross-bridge cycle"),
    ]),
    ("MODULE 12: Reproductive System", HexColor("#78281F"), [
        (82, "Male reproductive anatomy — testis, epididymis, vas deferens, prostate"),
        (83, "Female reproductive anatomy — ovary, uterus, fallopian tubes"),
        (84, "Reproductive embryology — gonadal development, Mullerian/Wolffian"),
        (85, "Menstrual cycle — physiology"),
        (86, "Spermatogenesis & oogenesis"),
        (87, "Fertilization, implantation, placenta development"),
    ]),
    ("MODULE 13: Skin & Special Senses", HexColor("#1A5276"), [
        (88, "Skin — layers, cells (keratinocytes, melanocytes, Langerhans, Merkel)"),
        (89, "Eye anatomy — layers, chambers, lens, retina"),
        (90, "Ear anatomy — outer, middle, inner ear"),
        (91, "Nose & paranasal sinuses — anatomy"),
    ]),
]

for mod_title, mod_color, topics_list in modules_phase2:
    story.append(module_block(mod_title, color=mod_color))
    for n_, t_ in topics_list:
        story.append(topic(n_, t_))
    story.append(sp(5))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 3
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 3 — MECHANISMS OF DISEASE"))
story.append(note("Inflammation → Immunity → Infection  |  Topics 92–115"))
story.append(sp(6))

modules_phase3 = [
    ("MODULE 14: Inflammation & Repair", MID_BLUE, [
        (92, "Acute inflammation — vascular & cellular events, chemical mediators"),
        (93, "Chronic inflammation — types, granuloma formation"),
        (94, "Wound healing — primary vs secondary intention"),
        (95, "Edema — types, mechanisms (Starling's forces)"),
        (96, "Shock — types (hypovolemic, septic, cardiogenic, neurogenic), pathophysiology & management"),
    ]),
    ("MODULE 15: Immunology", HexColor("#1E8449"), [
        (97,  "Innate immunity — cells, pattern recognition receptors, complement system"),
        (98,  "Adaptive immunity — T cells (CD4/CD8), B cells, MHC class I & II"),
        (99,  "Antibodies — classes (IgG, IgM, IgA, IgE, IgD), structure, functions"),
        (100, "Hypersensitivity reactions — Type I, II, III, IV (Gell & Coombs classification)"),
        (101, "Autoimmunity — mechanisms, molecular mimicry, examples"),
        (102, "Immunodeficiency disorders — primary (X-linked agammaglobulinemia, SCID, DiGeorge) & secondary"),
        (103, "Transplant immunology — rejection types (hyperacute, acute, chronic), HLA matching"),
        (104, "Tumor immunology — immune evasion mechanisms, immunotherapy (checkpoint inhibitors)"),
    ]),
    ("MODULE 16: Microbiology — Systematic", HexColor("#6C3483"), [
        (105, "Bacteriology basics — cell wall structure, Gram stain, classification, culture media"),
        (106, "Gram-positive cocci — Staphylococcus aureus, Streptococcus pyogenes, pneumoniae"),
        (107, "Gram-negative bacilli — E. coli, Klebsiella, Pseudomonas, Salmonella, Shigella"),
        (108, "Anaerobes — Clostridium (tetani, perfringens, difficile, botulinum), Bacteroides"),
        (109, "Mycobacterium — tuberculosis (Koch's bacillus), leprosy (M. leprae)"),
        (110, "Spirochetes — Treponema pallidum (syphilis), Leptospira, Borrelia (Lyme disease)"),
        (111, "Rickettsiae & Chlamydia — obligate intracellular organisms"),
        (112, "Virology — DNA viruses: Herpes simplex, EBV, CMV, Hepatitis B, HPV, Parvovirus B19"),
        (113, "RNA viruses — HIV, Influenza, Hepatitis C, Dengue, Rabies, Polio, Measles"),
        (114, "Fungi — Candida, Aspergillus, Cryptococcus, Mucor, dermatophytes"),
        (115, "Parasitology — Plasmodium, Leishmania, Entamoeba histolytica, Giardia, Helminths (roundworms, tapeworms)"),
    ]),
]

for mod_title, mod_color, topics_list in modules_phase3:
    story.append(module_block(mod_title, color=mod_color))
    for n_, t_ in topics_list:
        story.append(topic(n_, t_))
    story.append(sp(5))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 4
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 4 — INTEGRATED CLINICAL MEDICINE"))
story.append(note("Disease by Disease — Fully Integrated Across All MBBS Subjects  |  Topics 116–250"))
story.append(sp(6))

clinical_modules = [
    ("MODULE 17: Cardiovascular Diseases", HexColor("#B03A2E"), [
        (116, "Hypertension — essential & secondary causes, JNC/ACC-AHA guidelines"),
        (117, "Ischemic Heart Disease — stable angina, ACS, STEMI, NSTEMI, UA"),
        (118, "Myocardial Infarction — complications (VSD, MR, free wall rupture, Dressler)"),
        (119, "Heart Failure — systolic vs diastolic, HFrEF vs HFpEF, acute & chronic"),
        (120, "Arrhythmias — AF, AFL, VT, VF, heart blocks (1°/2°/3°), WPW syndrome"),
        (121, "Rheumatic Fever & Rheumatic Heart Disease — Jones criteria, mitral stenosis"),
        (122, "Infective Endocarditis — Duke criteria, organisms, HACEK group"),
        (123, "Pericarditis & Pericardial Effusion — Beck's triad, cardiac tamponade"),
        (124, "Cardiomyopathies — dilated (DCM), hypertrophic (HCM), restrictive (RCM), ARVC"),
        (125, "Congenital Heart Diseases — ASD, VSD, PDA, TOF, TGA, Eisenmenger's syndrome"),
        (126, "Aortic Dissection — DeBakey & Stanford classification, management"),
        (127, "Deep Vein Thrombosis & Pulmonary Embolism — Wells score, CTPA, anticoagulation"),
        (128, "Peripheral Vascular Disease — ABI, Fontaine classification"),
    ]),
    ("MODULE 18: Respiratory Diseases", HexColor("#1A5276"), [
        (129, "Pneumonia — CAP, HAP, VAP — CURB-65, organisms, treatment"),
        (130, "Tuberculosis — primary, secondary, miliary, EPTB, RNTCP/NTEP guidelines"),
        (131, "Bronchial Asthma — GINA classification, stepwise therapy"),
        (132, "COPD — GOLD staging, chronic bronchitis vs emphysema, management"),
        (133, "Interstitial Lung Diseases — IPF (UIP pattern), sarcoidosis, HP, COP"),
        (134, "Pleural Effusion (Light's criteria) & Pneumothorax — tension vs simple"),
        (135, "Lung Abscess & Bronchiectasis — causes, Reid's classification"),
        (136, "Pulmonary Hypertension — WHO classification, right heart catheterization"),
        (137, "Respiratory Failure — Type I (hypoxemic) & Type II (hypercapnic)"),
        (138, "Obstructive Sleep Apnea — Epworth scale, polysomnography, CPAP"),
        (139, "Lung Carcinoma — types (SCLC, NSCLC), paraneoplastic syndromes, staging"),
        (140, "ARDS — Berlin definition, P/F ratio, prone positioning, lung-protective ventilation"),
    ]),
    ("MODULE 19: Gastrointestinal Diseases", HexColor("#1E8449"), [
        (141, "GERD & Barrett's Esophagus — Prague classification, surveillance, PPI therapy"),
        (142, "Esophageal Carcinoma — SCC vs adenocarcinoma, geography, staging, management"),
        (143, "Peptic Ulcer Disease — H. pylori, NSAIDs, triple therapy, complications"),
        (144, "Gastric Carcinoma — Lauren classification, signet ring cells, Virchow's node"),
        (145, "Malabsorption Syndromes — celiac (anti-tTG), tropical sprue, Whipple's disease"),
        (146, "Inflammatory Bowel Disease — Crohn's disease vs Ulcerative Colitis (comparison)"),
        (147, "Irritable Bowel Syndrome — Rome IV criteria, management"),
        (148, "Colorectal Carcinoma — FAP, HNPCC/Lynch, Duke's/TNM staging, CEA"),
        (149, "Acute Appendicitis — Alvarado score, McBurney's point, surgical management"),
        (150, "Intestinal Obstruction — small vs large bowel, causes, Rigler's triad"),
        (151, "Acute Mesenteric Ischemia — causes, paper-white mucosa, management"),
    ]),
    ("MODULE 20: Hepatobiliary & Pancreatic Diseases", HexColor("#784212"), [
        (152, "Viral Hepatitis — A, B, C, D, E — serology, chronicity, prevention"),
        (153, "Alcoholic Liver Disease — steatosis → hepatitis → cirrhosis, AST:ALT >2"),
        (154, "NAFLD/NASH — metabolic syndrome link, NAS score, management"),
        (155, "Cirrhosis of Liver — Child-Pugh, MELD score, complications"),
        (156, "Portal Hypertension — causes, HVPG, varices, TIPSS"),
        (157, "Hepatic Encephalopathy — grades, ammonia, rifaximin, lactulose"),
        (158, "Hepatocellular Carcinoma — AFP, Barcelona staging (BCLC), sorafenib"),
        (159, "Acute Liver Failure — King's College criteria, N-acetylcysteine, transplant"),
        (160, "Cholelithiasis & Cholecystitis — Murphy's sign, Charcot's triad, ERCP"),
        (161, "Cholangiocarcinoma — Klatskin tumor, CA 19-9, Bismuth-Corlette classification"),
        (162, "Acute Pancreatitis — Ranson's criteria, CTSI, Atlanta classification, management"),
        (163, "Chronic Pancreatitis — Puestow procedure, steatorrhea, endocrine insufficiency"),
        (164, "Pancreatic Carcinoma — double duct sign, Courvoisier's law, Whipple's surgery"),
    ]),
    ("MODULE 21: Renal Diseases", HexColor("#6C3483"), [
        (165, "Acute Kidney Injury — KDIGO classification, pre-renal/renal/post-renal, FENa"),
        (166, "Chronic Kidney Disease — KDIGO staging, complications, renal osteodystrophy"),
        (167, "Nephrotic Syndrome — causes, Pathology, management, complications"),
        (168, "Nephritic Syndrome — hematuria, RBC casts, hypertension"),
        (169, "Glomerulonephritis — IgA nephropathy, MPGN, FSGS, membranous, RPGN"),
        (170, "Urinary Tract Infection & Pyelonephritis — organisms, imaging, treatment"),
        (171, "Nephrolithiasis — types (calcium oxalate, uric acid, struvite), metabolic workup"),
        (172, "Polycystic Kidney Disease — ADPKD vs ARPKD, PKD1/PKD2 genes"),
        (173, "Renal Cell Carcinoma — clear cell type, von Hippel-Lindau, paraneoplastic"),
        (174, "Renal Tubular Acidosis — Type 1, 2, 4"),
        (175, "Dialysis & Renal Replacement Therapy — HD vs PD, vascular access"),
    ]),
    ("MODULE 22: Endocrine & Metabolic Diseases", HexColor("#B03A2E"), [
        (176, "Diabetes Mellitus — T1DM, T2DM, LADA, MODY, microvascular & macrovascular complications"),
        (177, "DKA & HHS — diagnostic criteria, protocol management (ADA guidelines)"),
        (178, "Hypothyroidism — primary vs secondary, Hashimoto's, Myxedema coma"),
        (179, "Hyperthyroidism — Graves' disease, toxic nodule, thyroid storm"),
        (180, "Thyroid Carcinoma — papillary (PTC), follicular, medullary (RET gene), anaplastic"),
        (181, "Cushing's Syndrome — ACTH-dependent vs independent, dexamethasone suppression test"),
        (182, "Addison's Disease & Adrenal Crisis — autoimmune, TB, hyperpigmentation"),
        (183, "Primary Hyperaldosteronism (Conn's Syndrome) — hypokalemia, ARR"),
        (184, "Pheochromocytoma — 10% tumor, 24h urine catecholamines, surgical management"),
        (185, "Acromegaly & Gigantism — GH/IGF-1, oral GTT, transsphenoidal surgery"),
        (186, "Hyperprolactinemia — causes, galactorrhea, cabergoline vs bromocriptine"),
        (187, "Diabetes Insipidus & SIADH — water deprivation test, urine osmolality"),
        (188, "Hyperparathyroidism & Hypoparathyroidism — calcium-PTH relationship"),
        (189, "Metabolic Syndrome — IDF criteria, pathophysiology, management"),
        (190, "Obesity — WHO BMI classification, bariatric surgery indications"),
        (191, "Gout & Hyperuricemia — urate crystals, negative birefringence, allopurinol vs febuxostat"),
        (192, "Inborn Errors of Metabolism — PKU, MSUD, homocystinuria, galactosemia"),
    ]),
    ("MODULE 23: Hematological Diseases", HexColor("#1A5276"), [
        (193, "Iron Deficiency Anemia — causes, CBC, ferritin, transferrin saturation, management"),
        (194, "Megaloblastic Anemia — B12 vs folate deficiency, hypersegmented neutrophils"),
        (195, "Hemolytic Anemias — hereditary spherocytosis, G6PD deficiency, AIHA"),
        (196, "Sickle Cell Disease — HbS, vaso-occlusion, acute chest syndrome, hydroxyurea"),
        (197, "Thalassemia — alpha & beta types, Bart's hydrops fetalis, HbH disease"),
        (198, "Aplastic Anemia — pancytopenia, bone marrow biopsy, ATG + CSA, BMT"),
        (199, "Polycythemia Vera — JAK2 V617F, Chuvash, Rubinstein criteria, phlebotomy"),
        (200, "Leukemias — ALL (L1/L2/L3, childhood), AML (FAB M0–M7), CLL (Rai), CML (BCR-ABL, imatinib)"),
        (201, "Lymphomas — Hodgkin's (Reed-Sternberg cells, Ann Arbor) & Non-Hodgkin's (B vs T cell)"),
        (202, "Multiple Myeloma — CRAB criteria, M-protein, Bence Jones, bortezomib-based therapy"),
        (203, "Myelodysplastic Syndrome — cytopenia, dysplasia, IPSS score, risk of AML transformation"),
        (204, "Hemophilia A & B, von Willebrand Disease — factor levels, APTT, bleeding time"),
        (205, "ITP & TTP — platelet destruction mechanisms, ADAMTS13, plasma exchange"),
        (206, "DIC — consumptive coagulopathy, D-dimers, fibrinogen, treatment of cause"),
        (207, "Blood Transfusion — indications, reactions (hemolytic, febrile, TRALI), consent"),
    ]),
    ("MODULE 24: Neurological Diseases", HexColor("#1E8449"), [
        (208, "Stroke — ischemic (NIHSS, rtPA window) & hemorrhagic (ICH score)"),
        (209, "TIA — ABCD2 score, carotid Doppler, antiplatelet therapy"),
        (210, "Subarachnoid Hemorrhage — thunderclap headache, xanthochromia, aneurysm coiling"),
        (211, "Meningitis — bacterial (CSF: turbid, low glucose), viral, TB, fungal (India ink)"),
        (212, "Encephalitis — HSV (temporal lobe), autoimmune (anti-NMDA), management"),
        (213, "Epilepsy & Status Epilepticus — ILAE classification, IV lorazepam, valproate"),
        (214, "Parkinson's Disease — Lewy bodies, TRAP, dopaminergic pathway, levodopa"),
        (215, "Alzheimer's Disease & Dementia — neurofibrillary tangles, beta-amyloid, MMSE"),
        (216, "Multiple Sclerosis — demyelination, Dawson's fingers on MRI, disease-modifying therapy"),
        (217, "Guillain-Barre Syndrome — ascending paralysis, albuminocytologic dissociation, IVIG"),
        (218, "Myasthenia Gravis — anti-AChR antibodies, Tensilon test, thymectomy"),
        (219, "Motor Neuron Disease/ALS — UMN + LMN, El Escorial criteria, riluzole"),
        (220, "Peripheral Neuropathy — causes (DM, B12, leprosy), nerve conduction studies"),
        (221, "Brain Tumors — GBM (butterfly), meningioma, acoustic neuroma, medulloblastoma"),
        (222, "Headache — migraine (POUND mnemonic), cluster, tension-type, secondary causes"),
        (223, "Vertigo — BPPV (Dix-Hallpike, Epley), Meniere's, central vs peripheral"),
        (224, "Spinal Cord Disorders — compression, Brown-Sequard, syringomyelia, subacute combined degeneration"),
    ]),
    ("MODULE 25: Rheumatological & Connective Tissue Diseases", HexColor("#6C3483"), [
        (225, "Rheumatoid Arthritis — RF, anti-CCP, 2010 ACR/EULAR criteria, DMARDs, biologics"),
        (226, "SLE — ANA, anti-dsDNA, anti-Sm, 2019 EULAR/ACR criteria, lupus nephritis"),
        (227, "Sjogren's Syndrome — anti-Ro/La (SSA/SSB), sicca symptoms, minor salivary gland biopsy"),
        (228, "Systemic Sclerosis — anti-Scl70, anti-centromere, pulmonary fibrosis, renal crisis"),
        (229, "Polymyositis & Dermatomyositis — anti-Jo1, heliotrope rash, Gottron's papules, CK"),
        (230, "Vasculitis — GPA (c-ANCA), MPA (p-ANCA), EGPA, Takayasu, PAN, Kawasaki disease"),
        (231, "Ankylosing Spondylitis — HLA-B27, bamboo spine, NSAIDs, anti-TNF therapy"),
        (232, "Reactive Arthritis — Reiter's triad (can't see, can't pee, can't climb a tree)"),
        (233, "Psoriatic Arthritis — pencil-in-cup deformity, enthesitis, nail changes"),
        (234, "Osteoarthritis — Heberden's vs Bouchard's nodes, joint space narrowing"),
        (235, "Osteoporosis — DEXA scan, T-score, bisphosphonates, FRAX tool"),
        (236, "Antiphospholipid Syndrome — anti-cardiolipin, lupus anticoagulant, thrombosis, recurrent abortion"),
    ]),
    ("MODULE 26: Systemic Infectious Diseases", HexColor("#B03A2E"), [
        (237, "Sepsis & Septic Shock — Sepsis-3 definition, SOFA score, Surviving Sepsis Campaign"),
        (238, "HIV/AIDS — CDC staging, CD4 counts, OIs, ART regimens, prophylaxis"),
        (239, "Malaria — Plasmodium species, thick & thin smear, RDT, artesunate, ACT"),
        (240, "Typhoid Fever — Widal test, Rose spots, Typhidot, chloramphenicol, ciprofloxacin"),
        (241, "Dengue Fever — NS1, dengue IgM/IgG, dengue shock syndrome, fluid management"),
        (242, "Leptospirosis — Weil's disease, jaundice + AKI + uveitis, doxycycline"),
        (243, "Infective Endocarditis — clinical (Duke criteria), echo findings, antibiotic prophylaxis"),
        (244, "Cholera — El Tor biotype, rice-water stools, ORS, oral rehydration therapy"),
        (245, "Tetanus — C. tetani, risus sardonicus, opisthotonos, TIG, metronidazole"),
        (246, "Rabies — Negri bodies, Babes nodule, furious vs dumb rabies, PEP"),
        (247, "Meningococcal Disease — N. meningitidis, purpura fulminans, Waterhouse-Friderichsen"),
        (248, "Brucellosis — B. melitensis, undulant fever, SAT, doxycycline + rifampicin"),
        (249, "Anthrax — B. anthracis, Medusa head colonies, bioterrorism agent, ciprofloxacin"),
        (250, "Plague — Y. pestis, bubonic/pneumonic/septicemic, bubo, streptomycin"),
    ]),
]

for mod_title, mod_color, topics_list in clinical_modules:
    story.append(module_block(mod_title, color=mod_color))
    for n_, t_ in topics_list:
        story.append(topic(n_, t_))
    story.append(sp(4))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 5 — Surgery
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 5 — SURGERY — INTEGRATED"))
story.append(note("Surgical Principles → Specialty Surgery  |  Topics 251–287"))
story.append(sp(6))

surg_modules = [
    ("MODULE 27: General Surgical Principles", MID_BLUE, [
        (251, "Wound healing & surgical wounds — primary, secondary, tertiary intention"),
        (252, "Surgical infections — cellulitis, abscess, necrotizing fasciitis, gas gangrene"),
        (253, "Fluid & electrolyte management in surgery — Holliday-Segar, crystalloids vs colloids"),
        (254, "Pre & post-operative management — risk assessment, fasting, prophylaxis"),
        (255, "Blood transfusion in surgery — massive transfusion protocol"),
        (256, "Surgical nutrition — enteral vs parenteral, immune nutrition"),
        (257, "Surgical oncology principles — R0/R1/R2, sentinel node biopsy, margins"),
    ]),
    ("MODULE 28: Breast", HexColor("#B03A2E"), [
        (258, "Breast anatomy & benign diseases — fibroadenoma, ANDI, fibrocystic change"),
        (259, "Breast Carcinoma — TNM, ER/PR/HER2, neoadjuvant therapy, breast conservation"),
    ]),
    ("MODULE 29: Thyroid & Parathyroid Surgery", HexColor("#1E8449"), [
        (260, "Goiter — simple, multinodular, retrosternal, grading, surgery indications"),
        (261, "Thyroid Carcinoma — surgical approach (hemithyroidectomy vs total), RAI ablation"),
        (262, "Hyperparathyroidism — surgical aspects, Sestamibi scan, parathyroidectomy"),
    ]),
    ("MODULE 30: Abdominal Surgery", HexColor("#784212"), [
        (263, "Acute Abdomen — causes, clinical assessment, laparotomy vs laparoscopy"),
        (264, "Appendicitis — laparoscopic appendectomy, perforated appendix, Meckel's diverticulum"),
        (265, "Intestinal Obstruction — closed loop, volvulus, adhesions, surgical management"),
        (266, "Hernia — inguinal (direct/indirect/Bassini/TEP), femoral, umbilical, hiatal, incisional"),
        (267, "Peptic Ulcer — Billroth I & II, truncal vagotomy, bleeding ulcer management"),
        (268, "Colorectal Carcinoma — right vs left hemicolectomy, TME, stoma formation"),
        (269, "Anal & Perianal Disorders — hemorrhoids (Milligan-Morgan), fissures, fistulas (Parks)"),
    ]),
    ("MODULE 31: Hepato-Pancreato-Biliary Surgery", HexColor("#6C3483"), [
        (270, "Gallstones & Cholecystectomy — laparoscopic, open, Mirizzi syndrome"),
        (271, "Obstructive Jaundice — ERCP, PTC, Whipple vs PPPD, Klatskin classification"),
        (272, "Acute Pancreatitis — surgical aspects, necrosectomy, pseudocyst drainage"),
        (273, "Pancreatic Carcinoma — Whipple's (pancreaticoduodenectomy), staging, palliation"),
    ]),
    ("MODULE 32: Vascular Surgery", HexColor("#1A5276"), [
        (274, "Arterial diseases — critical limb ischemia, bypass grafting, embolectomy"),
        (275, "Varicose veins — CEAP classification, EVLA, Trendelenburg test"),
        (276, "Aortic Aneurysm — endovascular (EVAR) vs open repair, rupture management"),
    ]),
    ("MODULE 33: Urology", HexColor("#B03A2E"), [
        (277, "Urinary Calculi — ESWL, ureteroscopy, PCNL, medical expulsive therapy"),
        (278, "BPH & Prostate Carcinoma — PSA, TURP, Gleason score, TRUS biopsy"),
        (279, "Bladder Carcinoma — transitional cell, TURBT, intravesical BCG, radical cystectomy"),
        (280, "Testicular Tumors — seminoma vs non-seminoma, AFP/beta-hCG, retroperitoneal LND"),
    ]),
    ("MODULE 34: Orthopedic Surgery", HexColor("#1E8449"), [
        (281, "Fracture principles — AO/OTA classification, healing stages, implants"),
        (282, "Common fractures — Colles', scaphoid, femur neck (Garden), spine (ASIA)"),
        (283, "Dislocations — shoulder (Bankart, Hill-Sachs), hip (avascular necrosis)"),
        (284, "Bone infections — osteomyelitis (Cierny-Mader), septic arthritis, Brodie's abscess"),
        (285, "Bone tumors — osteosarcoma (sunburst), Ewing's sarcoma (onion peel), metastases"),
        (286, "Spine disorders — PIVD (Schmorl's nodes), spondylosis, cervical myelopathy"),
        (287, "Congenital disorders — DDH (Ortolani, Barlow), CTEV (Pirani score, Ponseti method)"),
    ]),
]

for mod_title, mod_color, topics_list in surg_modules:
    story.append(module_block(mod_title, color=mod_color))
    for n_, t_ in topics_list:
        story.append(topic(n_, t_))
    story.append(sp(4))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 6 — Specialty Medicine
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 6 — SPECIALTY MEDICINE"))
story.append(note("Pediatrics → OBG → Dermatology → Ophthalmology → ENT → Psychiatry  |  Topics 288–351"))
story.append(sp(6))

spec_modules = [
    ("MODULE 35: Pediatrics", MID_BLUE, [
        (288, "Growth & Development milestones — Denver, Gesell, developmental red flags"),
        (289, "Vaccination schedule — UIP/NIS, cold chain, AEFI, catch-up vaccination"),
        (290, "Neonatology — birth asphyxia (Apgar, HIE staging), RDS (surfactant), NEC, neonatal jaundice"),
        (291, "Protein Energy Malnutrition — Kwashiorkor, Marasmus, Gomez/Waterlow classification"),
        (292, "Childhood infections — measles, mumps, varicella, pertussis, diphtheria (Koplik spots)"),
        (293, "Acute Rheumatic Fever — Jones criteria, carditis, Sydenham's chorea, penicillin prophylaxis"),
        (294, "Congenital Heart Diseases — cyanotic vs acyanotic, surgical indications"),
        (295, "Pediatric Leukemias — ALL (most common childhood cancer), Hyper-CVAD"),
        (296, "Pediatric Nephrology — nephrotic syndrome (MCNS), UTI, glomerulonephritis"),
        (297, "Genetic disorders in children — Down syndrome features, Turner, Fragile X"),
        (298, "Pediatric emergencies — croup (steeple sign), epiglottitis (thumb sign), intussusception"),
    ]),
    ("MODULE 36: Obstetrics & Gynecology", HexColor("#B03A2E"), [
        (299, "Normal pregnancy — physiological changes, antenatal care schedule, partograph"),
        (300, "Hypertensive Disorders — pre-eclampsia (HELLP syndrome), eclampsia, MgSO4 therapy"),
        (301, "Antepartum Hemorrhage — placenta previa (Grades), abruptio placentae, Couvelaire uterus"),
        (302, "Postpartum Hemorrhage — 4 T's, bimanual compression, B-Lynch suture, uterotonics"),
        (303, "Ectopic Pregnancy — risk factors, serum beta-hCG, salpingostomy vs salpingectomy"),
        (304, "Gestational Diabetes — Carpenter-Coustan criteria, GDM management, fetal macrosomia"),
        (305, "Labor — stages, CTG interpretation, shoulder dystocia (HELPERR), operative delivery"),
        (306, "PCOS — Rotterdam criteria, insulin resistance, clomiphene, metformin, LOD"),
        (307, "Endometriosis — chocolate cyst, CA-125, ASRM staging, laparoscopic management"),
        (308, "Uterine Fibroids (Leiomyoma) — classification, myomectomy, uterine artery embolization"),
        (309, "Carcinoma Cervix — HPV 16/18, Pap smear, FIGO staging 2018, LEEP, LLETZ"),
        (310, "Carcinoma Endometrium — Figo staging, type I (endometrioid) vs type II, progesterone therapy"),
        (311, "Ovarian Tumors — Brenner, dysgerminoma, teratoma, granulosa cell, Meigs' syndrome"),
        (312, "Infertility — causes, semen analysis (WHO criteria), IUI, IVF, ICSI"),
        (313, "Contraception — OCP (Pearl index), IUCD (Lippes loop, Cu-T), sterilization methods"),
    ]),
    ("MODULE 37: Dermatology", HexColor("#1E8449"), [
        (314, "Psoriasis — Auspitz sign, Koebner phenomenon, PASI score, biologics (TNF inhibitors)"),
        (315, "Eczema/Atopic Dermatitis — IgE elevated, lichenification, tacrolimus, dupilumab"),
        (316, "Acne Vulgaris — comedones, propionibacterium, tretinoin, isotretinoin (teratogenic)"),
        (317, "Urticaria & Angioedema — dermographism, C1 inhibitor deficiency, cetirizine"),
        (318, "Pemphigus & Pemphigoid — Nikolsky sign, bulla, DIF (IgG in epidermis vs BMZ)"),
        (319, "Skin Infections — impetigo (S. aureus), cellulitis, dermatophytosis (KOH mount)"),
        (320, "Leprosy — M. leprae, Ridley-Jopling classification, WHO paucibacillary vs multibacillary"),
        (321, "Scabies (Sarcoptes scabiei) — burrow, Norwegian scabies, permethrin 5%"),
        (322, "STIs — syphilis (VDRL/FTA-ABS), gonorrhea (GC culture), chancroid, LGV, herpes"),
        (323, "Skin Tumors — melanoma (ABCDE, Breslow thickness), BCC (rodent ulcer), SCC"),
    ]),
    ("MODULE 38: Ophthalmology", HexColor("#1A5276"), [
        (324, "Refractive errors — myopia, hypermetropia, astigmatism, presbyopia, LASIK"),
        (325, "Glaucoma — angle closure vs open angle, tonometry, trabeculectomy"),
        (326, "Cataract — nuclear, cortical, PSC, phacoemulsification, IOL"),
        (327, "Diabetic Retinopathy — NPDR vs PDR, ETDRS, laser photocoagulation, anti-VEGF"),
        (328, "Hypertensive Retinopathy — Keith-Wagener-Barker classification"),
        (329, "Retinal Detachment — horseshoe tear, silicone oil, pneumatic retinopexy"),
        (330, "Uveitis — HLA-B27, sarcoidosis, toxoplasmosis, Behcet's disease"),
        (331, "Corneal Disorders — keratoconus (Munson's sign), corneal graft (PKP)"),
        (332, "Vitamin A deficiency — Bitot's spots, xerophthalmia, keratomalacia, national program"),
    ]),
    ("MODULE 39: ENT", HexColor("#6C3483"), [
        (333, "Otitis media — AOM, CSOM (safe vs unsafe), cholesteatoma, cortical mastoidectomy"),
        (334, "Otosclerosis — Schwartz sign, stapedectomy, Carhart's notch"),
        (335, "Sensorineural Hearing Loss — presbycusis, noise-induced, cochlear implant"),
        (336, "Sinusitis — CRS, nasal polyp, FESS, osteomeatal complex"),
        (337, "Allergic Rhinitis — ARIA classification, allergen avoidance, intranasal steroids"),
        (338, "Carcinoma Larynx — Glottic vs supraglottic, hoarseness, laryngectomy"),
        (339, "Tonsillitis & Adenoids — Paradise criteria for tonsillectomy, peritonsillar abscess"),
        (340, "Epistaxis — Little's area (Kiesselbach's plexus), posterior pack, sphenopalatine artery ligation"),
        (341, "Vertigo — BPPV (Dix-Hallpike positive), Meniere's disease (hydrops), Epley maneuver"),
    ]),
    ("MODULE 40: Psychiatry", HexColor("#B03A2E"), [
        (342, "Schizophrenia — positive vs negative symptoms, Schneider's FRS, antipsychotics"),
        (343, "Bipolar Disorder — mania criteria, mood stabilizers (lithium, valproate, lamotrigine)"),
        (344, "Major Depressive Disorder — PHQ-9, cognitive triad (Beck), SSRIs, ECT indications"),
        (345, "Anxiety Disorders — GAD (6 months), panic disorder (unexpected), OCD (ego-dystonic)"),
        (346, "Substance Use Disorders — CAGE, CAGE-AID, alcohol withdrawal (CIWA), AUDIT"),
        (347, "Delirium vs Dementia — 3D model, CAM tool, reversible causes of delirium"),
        (348, "Personality Disorders — cluster A/B/C, borderline (DBT), antisocial (no treatment)"),
        (349, "Eating Disorders — anorexia nervosa (BMI <17.5), bulimia, ARFID"),
        (350, "Suicide — Risk factors (SAD PERSONS), protective factors, zero suicide framework"),
        (351, "Psychopharmacology — receptor profiles, SSRI vs TCA vs MAOI, tardive dyskinesia"),
    ]),
]

for mod_title, mod_color, topics_list in spec_modules:
    story.append(module_block(mod_title, color=mod_color))
    for n_, t_ in topics_list:
        story.append(topic(n_, t_))
    story.append(sp(4))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 7 — Community Medicine & Pharmacology
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 7 — COMMUNITY MEDICINE & PHARMACOLOGY"))
story.append(note("Epidemiology → National Programs → Drug Classes  |  Topics 352–378"))
story.append(sp(6))

ph7_modules = [
    ("MODULE 41: Community Medicine / Preventive & Social Medicine (PSM)", MID_BLUE, [
        (352, "Epidemiology basics — study designs (cohort, case-control, RCT), bias types, confounding"),
        (353, "Communicable disease control — surveillance, outbreak investigation, quarantine"),
        (354, "Immunization — EPI/UIP/NIS, cold chain, VVM, AEFI, BCG scar rate"),
        (355, "National Health Programs — RNTCP/NTEP, NVBDCP, NPCDCS (NCDs), NPCB (blindness)"),
        (356, "Maternal & Child Health — ICDS, JSSK, PMSMA, Pradhan Mantri Matru Vandana"),
        (357, "Nutrition programs — POSHAN 2.0, mid-day meal, ICDS supplementary nutrition"),
        (358, "Environmental health — water quality (coliform count), air pollution (PNC2.5), food hygiene"),
        (359, "Occupational health — silicosis, asbestosis (mesothelioma risk), byssinosis, coal worker's pneumoconiosis"),
        (360, "Biostatistics — mean/median/mode, SD, sensitivity/specificity, LR+/LR-, NNT, NNH"),
        (361, "Health systems — Bhore Committee, Mudaliar Committee, NHM, Ayushman Bharat, HWC"),
    ]),
    ("MODULE 42: Pharmacology — Comprehensive", HexColor("#1E8449"), [
        (362, "General pharmacology — pharmacokinetics (ADME), pharmacodynamics, therapeutic index"),
        (363, "ANS pharmacology — adrenergic agonists/blockers, cholinergic agonists/blockers (atropine)"),
        (364, "Cardiovascular drugs — ACEi, ARBs, beta-blockers, CCBs, nitrates, digoxin, statins"),
        (365, "Diuretics — loop (furosemide), thiazide, K+-sparing, CAI, osmotic"),
        (366, "Anticoagulants — heparin (LMWH vs UFH), warfarin, DOACs (rivaroxaban, apixaban), thrombolytics"),
        (367, "GI drugs — PPIs (omeprazole), H2 blockers (ranitidine), metoclopramide, ondansetron, ursodeoxycholic acid"),
        (368, "Respiratory drugs — SABA/LABA, SAMA/LAMA, ICS, methylxanthines, antitussives, N-acetylcysteine"),
        (369, "CNS drugs — antiepileptics (sodium valproate, carbamazepine, levetiracetam), antipsychotics, antidepressants"),
        (370, "Analgesics — paracetamol, NSAIDs (COX1 vs COX2), opioids (morphine), adjuvant analgesics"),
        (371, "Antibiotics — penicillins, cephalosporins, carbapenems, macrolides, fluoroquinolones, aminoglycosides, tetracyclines"),
        (372, "Antitubercular drugs — HRZE regimen, side effects (rifampicin orange urine, ethambutol optic neuritis)"),
        (373, "Antifungal & antiviral drugs — azoles, polyenes (amphotericin B), acyclovir, oseltamivir, remdesivir"),
        (374, "Antiparasitic drugs — chloroquine, ACT (artemisinin), primaquine (G6PD), albendazole, ivermectin"),
        (375, "Endocrine pharmacology — insulin types, OHAs (metformin, sulfonylureas, GLP-1RA, SGLT2i), levothyroxine"),
        (376, "Cancer chemotherapy — alkylating agents, antimetabolites, vinca alkaloids, taxanes, targeted therapy, immunotherapy"),
        (377, "Immunosuppressants — calcineurin inhibitors (tacrolimus, cyclosporine), azathioprine, mycophenolate, steroids"),
        (378, "Vaccines & Biologicals — types of vaccines (live, killed, subunit, mRNA), adjuvants, cold chain, immunoglobulins"),
    ]),
]

for mod_title, mod_color, topics_list in ph7_modules:
    story.append(module_block(mod_title, color=mod_color))
    for n_, t_ in topics_list:
        story.append(topic(n_, t_))
    story.append(sp(4))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 8 — Forensic Medicine
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 8 — FORENSIC MEDICINE & TOXICOLOGY"))
story.append(note("Death → Identity → Wounds → Toxicology → Medical Jurisprudence  |  Topics 379–385"))
story.append(sp(6))

story.append(module_block("MODULE 43: Forensic Medicine — Complete", color=HexColor("#6C3483")))
forensic_topics = [
    (379, "Death — somatic vs molecular, signs of death, postmortem changes (rigor mortis, livor mortis, decomposition)"),
    (380, "Identification — age (Gustafson's method), sex (pelvis), stature (Pearson), fingerprints (Galton), DNA fingerprinting"),
    (381, "Wounds — incised, lacerated, contused, puncture, firearm — medico-legal significance"),
    (382, "Asphyxia — hanging (ligature mark), strangulation (Tardieu spots), drowning (Diatom test), suffocation, positional"),
    (383, "Sexual offences — rape (POCSO Act 2012), examination protocol (2-finger test abolished), hymen"),
    (384, "Toxicology — organophosphates (SLUD), corrosives, heavy metals (arsenic, lead), alcohol, carbon monoxide, snake venom"),
    (385, "Medical jurisprudence — informed consent, negligence (Bolam test), MLC, dying declaration, insanity defense (McNaughten)"),
]
for n_, t_ in forensic_topics:
    story.append(topic(n_, t_))

story.append(PageBreak())

# ═══════════════════════════════════════════════════════════
# PHASE 9 — Integrated High-Yield Revision
# ═══════════════════════════════════════════════════════════
story.append(phase_block("PHASE 9 — INTEGRATED HIGH-YIELD REVISION"))
story.append(note("Cross-Cutting Topics + Radiology Principles  |  Topics 386–402"))
story.append(sp(6))

story.append(module_block("MODULE 44: Cross-Cutting High-Yield Topics", color=HexColor("#B03A2E")))
cc_topics = [
    (386, "Paraneoplastic syndromes — SIADH, Cushing's, Lambert-Eaton, DIC — tumor associations"),
    (387, "Autoimmune diseases — integrated comparison table, antibodies vs diseases"),
    (388, "Amyloidosis — AL vs AA vs transthyretin (ATTR), Congo red, apple-green birefringence"),
    (389, "Sarcoidosis — non-caseating granuloma, Kveim test, ACE, multiorgan involvement"),
    (390, "Vasculitis — complete CHCC 2012 classification — large/medium/small vessel"),
    (391, "Granulomatous diseases — comparison: TB, sarcoid, Crohn's, leprosy, fungal"),
    (392, "Hyponatremia & Hypernatremia — causes, serum osmolality approach, treatment"),
    (393, "Hypokalemia & Hyperkalemia — ECG changes, causes, emergency treatment"),
    (394, "Hypercalcemia — causes (HHM vs PTH), Bones/Stones/Moans/Groans — management"),
    (395, "Hypocalcemia — Chvostek, Trousseau, calcium-phosphate-PTH-Vit D axis"),
    (396, "Metabolic acidosis & alkalosis — anion gap, delta ratio, Winter's formula, stepwise approach"),
]
for n_, t_ in cc_topics:
    story.append(topic(n_, t_))
story.append(sp(6))

story.append(module_block("MODULE 45: Radiology — Integrated with Diseases", color=HexColor("#1A5276")))
radio_topics = [
    (397, "Chest X-ray interpretation — systematic ABCDE approach — common NEET PG X-ray findings"),
    (398, "CT scan basics — HU values, contrast phases, head CT (bleed vs infarct)"),
    (399, "MRI principles — T1 vs T2 signals, FLAIR, DWI — indications over CT"),
    (400, "Ultrasound — abdominal (FAST exam), thyroid (TI-RADS), obstetric (biometry), Doppler"),
    (401, "Nuclear medicine — PET-CT (FDG), thyroid scan (Tc-99m), HIDA scan, V/Q scan"),
    (402, "Interventional radiology — TIPSS, ERCP, embolization, CT-guided biopsy, angioplasty"),
]
for n_, t_ in radio_topics:
    story.append(topic(n_, t_))

story.append(sp(12))
story.append(hr(ACCENT_BLUE))
story.append(sp(8))

# Final summary box
story.append(info_box(
    "Curriculum Summary",
    [
        "Total Integrated Topics: 402+",
        "Total Learning Phases: 9",
        "Total Curriculum Modules: 45",
        "Points Taught Per Topic: 55 (Definition to Last-Minute Facts)",
        "Textbooks Referenced: Robbins, Harrison's, Guyton, Katzung/KDT, Bailey & Love, Park's, Ananthanarayan",
        "NEET PG Orientation: Every topic annotated with high-yield exam-focused clinical pearls",
        "Format: Suitable for first learning AND final rapid revision",
    ],
    bg=LIGHT_BLUE, title_color=MID_BLUE
))

story.append(sp(10))

# Closing motivational box
closing_data = [[
    Paragraph(
        "<b><font color='#1B4F72' size=13>You are now equipped with the complete roadmap.</font></b><br/><br/>"
        "<font color='#333333' size=9>Every topic, every subject, every detail — all integrated, all connected.<br/>"
        "Work through this curriculum topic by topic and the NEET PG examination<br/>"
        "will become a test you are fully prepared for.</font><br/><br/>"
        "<font color='#E67E22' size=10><b>Start strong. Stay consistent. Master it all.</b></font>",
        S("ClosingPara", fontSize=9, fontName="Helvetica", leading=14,
          alignment=TA_CENTER, textColor=DARK_BLUE)
    )
]]
closing_t = Table(closing_data, colWidths=[W - 3*cm])
closing_t.setStyle(TableStyle([
    ("BACKGROUND", (0,0), (-1,-1), YELLOW_BG),
    ("BOX", (0,0), (-1,-1), 1.5, ACCENT_BLUE),
    ("TOPPADDING", (0,0), (-1,-1), 16),
    ("BOTTOMPADDING",(0,0),(-1,-1), 16),
    ("LEFTPADDING", (0,0), (-1,-1), 20),
    ("RIGHTPADDING",(0,0),(-1,-1), 20),
    ("ALIGN", (0,0), (-1,-1), "CENTER"),
]))
story.append(closing_t)

# ── BUILD ────────────────────────────────────────────────────────────────────
doc.build(story)
print(f"PDF generated: {OUTPUT_PATH}")

Successfully replaced 1 instance(s) of the string in '/home/daytona/workspace/neet-pg-curriculum/generate_pdf.py'