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Here is the complete extracted report from the SENSA CORE ST-200CC Smart ABG analyzer:
Arterial Blood Gas Report - Patient Details
Device: SENSA CORE ST-200CC Smart
Time: 09:13 AM
Sample Type: Arterial
| Field | Value |
|---|---|
| Patient Name | Muniswamy |
| Age | 40 years |
| Gender | Male |
| Department | ICU |
| Hospital | Medax |
Measured Parameters
| Parameter | Value | Units | Status |
|---|---|---|---|
| pH | 7.29 | - | LOW (Orange) |
| pCO2 | 49.0 | mmHg | HIGH (Red) |
| pO2 | 106.3 | mmHg | High (Red) |
| Hematocrit (Hct) | 26.22 | % | LOW (Orange) |
| Sodium (Na+) | 122 | mmol/L | LOW (Orange) |
| Potassium (K+) | 2.84 | mmol/L | LOW (Orange) |
| Ionized Calcium (iCa++) | 0.83 | mmol/L | LOW (Orange) |
| Chloride (Cl-) | 92 | mmol/L | LOW (Orange) |
| Glucose (Glu) | 89 | mg/dL | NORMAL (Green) |
| Lactate (Lac) | 0.71 | mmol/L | NORMAL (Green) |
Calculated Parameters
| Parameter | Value | Units | Status |
|---|---|---|---|
| Hemoglobin (Hb) | 8.74 | g/dL | LOW |
| cHCO3- [std] | 22.90 | mmol/L | NORMAL |
| cHCO3- [p] | 24.0 | mmol/L | - |
| ctCO2 [p] | 25.4 | mmol/L | NORMAL |
| O2 Saturation (sO2) | 98.99 | % | - |
| O2 Content (O2Ct) | 12.36 | Vol% | - |
| pO2% | 13.98 | % | - |
| Alveolar-arterial O2 gradient (AaDO2) | -15.1 | mmHg | - |
| Normalized Calcium (nCa) | 0.78 | mmol/L | - |
| Total Calcium (TCa) | 1.57 | mmol/L | - |
| Base Excess (BE) | -1.84 | mmol/L | - |
| Base Excess Blood (BE-B) | -1.90 | mmol/L | - |
| Base Excess ECF (BE-ECF) | -2.74 | mmol/L | - |
| Anion Gap (AG-Na) | 5.95 | mmol/L | - |
| Anion Gap with K (AG-K) | 8.78 | mmol/L | - |
| Alveolar pO2 (A) | 91.11 | mmHg | - |
| a/A ratio | 116.6 | % | - |
| Osmolality (mOsm) | 246.7 | mmol/kg | - |
| pH [TC] | 7.29 | - | - |
| pCO2 [TC] | 48.95 | mmHg | - |
| pO2 [TC] | 106.2 | mmHg | - |
| P/F Ratio (pO2/FiO2) | 506.0 | mmHg | - |
| FiO2 | 0.21 | - | - |
| Patient Temperature | 37.0 | °C | - |
Clinical Interpretation
Acid-Base Status: The pH of 7.29 indicates acidemia. The pCO2 is mildly elevated at 49.0 mmHg (respiratory component), and bicarbonate is near-normal at 22.9 mmol/L. This pattern is consistent with respiratory acidosis (possibly with a metabolic component given the mildly negative base excess of -1.84).
Key Abnormalities:
- Anemia: Hb 8.74 g/dL and Hct 26.22% - significant anemia
- Hyponatremia: Na+ 122 mmol/L - severe hyponatremia
- Hypokalemia: K+ 2.84 mmol/L - low potassium
- Hypocalcemia: iCa++ 0.83 mmol/L - low ionized calcium
- Low osmolality: 246.7 mmol/kg - hypoosmolar state (consistent with hyponatremia)
- Hypochloremia: Cl- 92 mmol/L
Reassuring findings: Glucose normal, lactate normal (no significant tissue hypoperfusion), good oxygenation (pO2 106.3 mmHg, SpO2 99%, P/F ratio 506).
Disclaimer: This is an informational summary only. All clinical decisions should be made by the treating physician.
Inj epimetz and inj lasix can go together
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Inj Epimetz metronidazole Inj Lasix furosemide compatibility drug interaction IV same line
Inj Epimetz (Metronidazole) + Inj Lasix (Furosemide) - Compatibility & Interaction
Quick Answer
Yes, they can generally be given together - but NOT in the same IV line (Y-site or same syringe). They must be administered separately.
Drug Interaction (Systemic)
| Aspect | Details |
|---|---|
| Interaction severity | LOW RISK / No significant pharmacodynamic interaction |
| Mechanism | No direct drug-drug interaction between metronidazole and furosemide |
| Can be co-administered? | Yes, with standard monitoring |
There is no clinically significant pharmacodynamic or pharmacokinetic interaction between metronidazole and furosemide when given together.
IV Physical Compatibility (Y-site / Same Line)
This is the more important concern in ICU practice:
- Furosemide is highly alkaline (pH ~8-9)
- Metronidazole IV solution is slightly acidic (pH ~5-7)
- Mixing them at the Y-site or in the same syringe can cause precipitation or instability
- The Thames Valley Critical Care Network IV Compatibility Chart shows furosemide and metronidazole compatibility is conditional - it depends on concentration and formulation
Best practice:
- Flush the IV line with normal saline (NS) between the two drugs if using the same line
- Ideally, use separate IV lines for each
- Do NOT mix in the same syringe or bag
Clinical Context - This Patient
Looking at this patient's ABG:
- Severe hyponatremia (Na+ 122 mmol/L) - Lasix (furosemide) needs careful use; aggressive diuresis can worsen hyponatremia
- Hypokalemia (K+ 2.84 mmol/L) - Furosemide causes further K+ loss; potassium replacement should be ensured alongside Lasix
- Low ionized calcium (iCa++ 0.83) - Furosemide also causes Ca++ loss; watch for worsening
Summary
| Question | Answer |
|---|---|
| Pharmacological interaction? | No significant interaction |
| Same syringe? | NO - do not mix |
| Same IV line simultaneously? | Caution - flush with NS between drugs |
| Separate lines? | Preferred in ICU |
| Monitoring needed? | Na+, K+, Ca++ - all already low in this patient |
Disclaimer: Always verify compatibility with your hospital pharmacist or using a validated IV compatibility reference such as Trissel's or Micromedex before administration.
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