1.50 / male vegetarian, presented with pallor, paresthesia of extremities O/E he had beefy tongue what is your diagnosis? How will you investigate this patient further and establish the diagnosis. Classify RBC disorders according to etiology. 2.30 years female immediately after delivery went into sudden circulatory failure. She had profuse bleeding per vaginum and from venepuncture sites. What is your diagnosis? What is the Pathophysiology? How will you investigate this patient? 3.8 years old girl presented with malaise and fatigue. On examination yellowish sclera with hepatosplenomegaly noted. Family history revealed similar complaints in her sibling also. Her Hemoglobin level is 7.8 g/dl. X-Ray skull showed “crewcut” appearance. a) What is your diagnosis? b) Write in detail about etiopathogenesis, morphology and laboratory investigations needed to confirm the diagnosis.