diuretics classification mechanism of action clinical pharmacology 2025

python -m markitdown "/home/daytona/workspace/attachments/5fddce1d-0e9d-4601-b8e8-aac8a9806ae8/Epilepsy 30-10-2023.ppt"

cd /home/daytona/workspace && python3 -c " from pptx import Presentation import sys prs = Presentation('/home/daytona/workspace/attachments/5fddce1d-0e9d-4601-b8e8-aac8a9806ae8/Epilepsy 30-10-2023.ppt') for i, slide in enumerate(prs.slides): print(f'--- SLIDE {i+1} ---') for shape in slide.shapes: if hasattr(shape, 'text') and shape.text.strip(): print(shape.text) print() "

pip install python-pptx --user --quiet 2>&1 | tail -3

which libreoffice && libreoffice --version

mkdir -p /home/daytona/workspace/epilepsy-ppt && libreoffice --headless --convert-to pptx "/home/daytona/workspace/attachments/5fddce1d-0e9d-4601-b8e8-aac8a9806ae8/Epilepsy 30-10-2023.ppt" --outdir /home/daytona/workspace/epilepsy-ppt/ 2>&1

cp "/home/daytona/workspace/attachments/5fddce1d-0e9d-4601-b8e8-aac8a9806ae8/Epilepsy 30-10-2023.ppt" /tmp/epilepsy.ppt && chmod 777 /tmp/epilepsy.ppt && libreoffice --headless --convert-to pptx /tmp/epilepsy.ppt --outdir /home/daytona/workspace/epilepsy-ppt/ 2>&1

ls -la /home/daytona/workspace/epilepsy-ppt/ && libreoffice --headless --convert-to txt /tmp/epilepsy.ppt --outdir /home/daytona/workspace/epilepsy-ppt/ 2>&1

mkdir -p /home/daytona/workspace/epilepsy-out && chmod 777 /home/daytona/workspace/epilepsy-out && libreoffice --headless --convert-to txt /tmp/epilepsy.ppt --outdir /home/daytona/workspace/epilepsy-out/ 2>&1

ls -la /home/daytona/workspace/ && libreoffice --headless --convert-to txt /tmp/epilepsy.ppt --outdir /home/daytona/workspace/epilepsy-out/ 2>&1

libreoffice --headless --convert-to odp /tmp/epilepsy.ppt --outdir /home/daytona/workspace/epilepsy-out/ 2>&1 && ls /home/daytona/workspace/epilepsy-out/

cd /home/daytona/workspace/epilepsy-out && unzip -o epilepsy.odp -d epilepsy_odp_extracted 2>&1 | tail -5 && ls epilepsy_odp_extracted/

python3 -c " import zipfile, os odp = '/home/daytona/workspace/epilepsy-out/epilepsy.odp' out = '/home/daytona/workspace/epilepsy-out/odp_extracted' os.makedirs(out, exist_ok=True) with zipfile.ZipFile(odp) as z: z.extractall(out) print('Done:', os.listdir(out)) " 2>&1

python3 -c " import xml.etree.ElementTree as ET import re tree = ET.parse('/home/daytona/workspace/epilepsy-out/odp_extracted/content.xml') root = tree.getroot() # Extract all text ns = {'text': 'urn:oasis:names:tc:opendocument:xmlns:text:1.0', 'draw': 'urn:oasis:names:tc:opendocument:xmlns:drawing:1.0', 'presentation': 'urn:oasis:names:tc:opendocument:xmlns:presentation:1.0', 'office': 'urn:oasis:names:tc:opendocument:xmlns:office:1.0'} slide_num = 0 for page in root.iter('{urn:oasis:names:tc:opendocument:xmlns:drawing:1.0}page'): slide_num += 1 print(f'=== SLIDE {slide_num} ===') for elem in page.iter(): if elem.tag == '{urn:oasis:names:tc:opendocument:xmlns:text:1.0}p': text = ''.join(elem.itertext()).strip() if text: print(text) print() " 2>&1

Medical educational flowchart titled "Classification of Epileptic Seizures". Clean white background with color-coded branches. Top box: "EPILEPTIC SEIZURES" in dark blue. Two main branches below: Left branch in teal: "PARTIAL (FOCAL) SEIZURES - One side of brain" splitting into two sub-boxes: "A. SIMPLE PARTIAL (Jacksonian) - Consciousness PRESERVED - One limb/muscle group - Motor, sensory or speech disturbance - EEG: Contralateral discharge" and "B. COMPLEX PARTIAL (Temporal Lobe) - Consciousness IMPAIRED/LOST - Automatisms (lip smacking, hand movements) - Confused/dazed behavior - EEG: Bilateral spread". Right branch in orange: "GENERALIZED SEIZURES - Both brain hemispheres" splitting into six sub-boxes arranged vertically: "1. TONIC-CLONIC (Grand Mal) - Tonic phase: rigid stiffening - Clonic phase: rhythmic jerking - Loss of consciousness", "2. ABSENCE (Petit Mal) - Blank stare 5-10 sec - No falling - Eyelid flutter - EEG: 3/sec spike-wave", "3. TONIC - Sustained muscle stiffening", "4. CLONIC - Rhythmic jerking only", "5. ATONIC (Drop Attack) - Sudden loss of muscle tone - Patient falls", "6. MYOCLONIC - Sudden brief muscle jerk". At the bottom a red warning box: "STATUS EPILEPTICUS - Seizures lasting 30+ min without recovery - MEDICAL EMERGENCY". All text clear and readable, professional medical infographic style.

Medical educational diagram titled "How Antiseizure Drugs Work at the Synapse" showing a detailed neuron synapse illustration. Dark navy blue background with bright colored labels. Center shows a presynaptic neuron terminal on top and postsynaptic neuron membrane at bottom with synaptic cleft in between. Label the following components with colored arrows and drug names: 1) Voltage-gated Na+ channels on neuron membrane - red label: "Na+ CHANNEL BLOCKERS: Phenytoin, Carbamazepine, Lamotrigine, Valproate, Oxcarbazepine, Topiramate, Lacosamide - Block rapid firing" 2) T-type Ca2+ channels - orange label: "Ca2+ CHANNEL BLOCKERS: Ethosuximide - Blocks thalamic oscillation in Absence seizures" 3) GABA vesicles releasing into synapse - green label: "GABA ENHANCERS" with sub-labels: "Barbiturates (Phenobarbital) - Keep Cl- channel OPEN LONGER" and "Benzodiazepines (Clonazepam) - Open Cl- channel MORE OFTEN" and "Vigabatrin - Block GABA breakdown enzyme" and "Tiagabine - Block GABA reuptake" 4) Glutamate/AMPA receptors on postsynaptic - purple label: "GLUTAMATE BLOCKERS: Perampanel, Topiramate, Felbamate - Block AMPA receptors" 5) SV2A protein on vesicle - yellow label: "SV2A MODULATORS: Levetiracetam, Brivaracetam". Bottom text: "GABA = Brain Brakes (Inhibitory) | Glutamate = Brain Accelerator (Excitatory)". Clean professional medical illustration style.

Medical educational flowchart titled "Drug Selection by Seizure Type" on clean white background. A decision-tree style chart with seizure type boxes on the left connected by arrows to drug choice boxes on the right. Color code: seizure boxes in light blue, first-line drug boxes in green, second-line in yellow, avoid boxes in red. Layout: Row 1: "PARTIAL SEIZURES (Simple or Complex)" → green box "FIRST LINE: Carbamazepine, Phenytoin, Valproate, Lamotrigine" → yellow box "ALTERNATIVES: Oxcarbazepine, Topiramate, Levetiracetam, Gabapentin". Row 2: "GENERALIZED TONIC-CLONIC (Grand Mal)" → green box "FIRST LINE: Valproate, Carbamazepine, Phenytoin, Phenobarbital" → yellow "ALTERNATIVES: Lamotrigine, Topiramate, Levetiracetam". Row 3: "ABSENCE SEIZURES (Petit Mal)" → green "FIRST LINE: Ethosuximide, Valproate" → yellow "ALTERNATIVE: Clonazepam" → red box "AVOID: Phenytoin, Carbamazepine (worsen absence!)". Row 4: "MYOCLONIC SEIZURES" → green "FIRST LINE: Valproate, Clonazepam" → yellow "ALTERNATIVES: Lamotrigine, Levetiracetam". Row 5: "DRAVET SYNDROME (infants)" → green "APPROVED: Cannabidiol, Stiripentol, Fenfluramine". Row 6: "STATUS EPILEPTICUS" → green "IV Lorazepam/Diazepam → IV Phenytoin/Fosphenytoin → IV Phenobarbital". Bold title, clean arrows, professional medical infographic.

Medical educational diagram titled "Status Epilepticus - Emergency Management Flowchart" on a dark red to black gradient background with white and yellow text. Step-by-step vertical flowchart with timed steps connected by downward arrows. Step boxes are rectangular. Step 0: Yellow box "SEIZURE LASTS MORE THAN 5 MINUTES or BACK-TO-BACK SEIZURES = STATUS EPILEPTICUS - Call for emergency help immediately". Step 1 (0-5 min): Green box "IMMEDIATE ACTIONS: - Protect airway - Give oxygen - Check blood glucose - IV access - Monitor vital signs". Step 2 (5-20 min): Blue box "FIRST LINE TREATMENT: IV Lorazepam 0.1 mg/kg OR IV Diazepam - Most effective at stopping seizures early - If no IV: rectal diazepam or IM midazolam". Step 3 (20-40 min): Orange box "IF SEIZURE CONTINUES: IV Fosphenytoin/Phenytoin OR IV Valproate OR IV Levetiracetam - Load with antiseizure drug". Step 4 (40-60 min): Red box "REFRACTORY STATUS EPILEPTICUS: ICU admission - IV Phenobarbital - Anesthetic doses: Propofol or Midazolam infusion". Warning box at bottom: "COMPLICATIONS: Hypoxia, Brain damage, Acidosis, Hyperthermia, Cardiac collapse, Death". Professional medical emergency flowchart style, clear readable text.

Medical educational comparison diagram titled "Seizure Types at a Glance - EEG Patterns and Brain Involvement" showing 4 side-by-side panels on a clean white background. Panel 1 (teal border): "Simple Partial Seizure" - drawing of a brain with one small red spot highlighted on one hemisphere, below it a jagged EEG line labeled "focal discharge, one side only", below: "Conscious: YES, Duration: seconds-minutes, Symptoms: twitching of one limb". Panel 2 (purple border): "Complex Partial Seizure" - brain drawing with one larger highlighted area, EEG shows bilateral spread, "Conscious: IMPAIRED, Automatisms: YES (lip smacking, hand movements)". Panel 3 (orange border): "Tonic-Clonic Seizure" - brain drawing with both hemispheres fully highlighted in red, EEG shows high voltage fast spikes then rhythmic spikes, "Phase 1 TONIC: stiffening, Phase 2 CLONIC: jerking, Conscious: LOST". Panel 4 (green border): "Absence Seizure" - brain with thalamus highlighted in yellow, EEG shows classic 3 per second regular spike-and-wave pattern clearly drawn, "Conscious: BRIEFLY LOST, Duration: 5-10 seconds, Looks like: blank stare/daydreaming, Common in: children". Bottom row: color-coded summary bar. Professional medical textbook illustration style, labeled clearly.