Orris

Summerize thal and provide comparative results with other similar trials

Reading File
Now let me extract the PDF content and search for related trials in parallel.
Running Command

python3 -c " import pdfplumber with pdfplumber.open('/home/daytona/workspace/attachments/5f6e90a4-e773-48e2-a0bc-68d094cb61cc/de-boniface-et-al-2026-omission-of-completion-axillary-dissection-in-patients-with-breast-cancer-and-sentinel-lymph.pdf') as pdf: for i, page in enumerate(pdf.pages): text = page.extract_text() if text: print(f'--- PAGE {i+1} ---') print(text) "

Now let me search for the key comparable trials (ACOSOG Z0011, IBCSG 23-01, AMAROS, OTOASOR) in parallel.
Searching PubMed

SENOMAC trial sentinel lymph node macrometastases axillary dissection omission

Searching PubMed

ACOSOG Z0011 sentinel lymph node positive axillary dissection omission breast cancer

Searching PubMed

AMAROS OTOASOR IBCSG 23-01 sentinel node positive axillary treatment breast cancer randomized

Let me get the key SENOMAC NEJM paper abstract and search for the landmark comparison trials more precisely.
Reading Article

PMID: 38598571

Searching PubMed

ACOSOG Z0011 sentinel node breast cancer axillary overall survival 10-year

Searching PubMed

AMAROS axillary radiotherapy versus dissection sentinel node positive breast cancer

Searching PubMed

IBCSG 23-01 micrometastases sentinel node axillary dissection omission breast cancer

Let me get key abstracts for the major comparison trials and the CADONOT meta-analysis.
Reading Article

PMID: 28898379

Reading Article

PMID: 36383926

Reading Article

PMID: 40220731

Reading Article

PMID: 39121881

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HTTP 400 for https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?tool=orrisai&email=dev%40orris.ai&api_key=***&db=pubmed&id=36383926&rettype=abstract&retmode=xml

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