Here is a curated list of peer-reviewed reference articles on medication chart review / potentially inappropriate prescribing (PIP) in elderly patients, organized by Beers Criteria, STOPP/START Criteria, and combined/general tools.
Beers Criteria — Key References
[Systematic Review · 2021]
Praxedes MFDS, Pereira GCDS, Lima CFDM et al.
Prescribing potentially inappropriate medications for the elderly according to Beers Criteria: systematic review. Ciênc Saúde Coletiva. 2021 Aug.
PMID: 34378710
[Systematic Review · 2018]
Motter FR, Fritzen JS, Hilmer SN et al.
Potentially inappropriate medication in the elderly: a systematic review of validated explicit criteria. Eur J Clin Pharmacol. 2018 Jun.
PMID: 29589066
Comprehensively reviews and compares 19 validated explicit criteria tools including Beers and STOPP/START.
[Systematic Review + Meta-Analysis · 2023]
Tian F, Chen Z, Zeng Y.
Prevalence of Use of Potentially Inappropriate Medications Among Older Adults Worldwide: A Systematic Review and Meta-Analysis. JAMA Netw Open. 2023 Aug.
PMID: 37531105
Pooled global prevalence data using both Beers and STOPP criteria; major high-impact reference.
STOPP/START Criteria — Key References
[Systematic Review + Meta-Analysis · 2016]
Hill-Taylor B, Walsh KA, Stewart S et al.
Effectiveness of the STOPP/START criteria: systematic review and meta-analysis of randomized controlled studies. J Clin Pharm Ther. 2016 Apr.
PMID: 26990017
Landmark meta-analysis specifically evaluating STOPP/START as a clinical intervention tool.
[Systematic Review + Meta-Analysis · 2018]
Dalton K, O'Brien G, O'Mahony D et al.
Computerised interventions designed to reduce potentially inappropriate prescribing in hospitalised older adults: a systematic review and meta-analysis. Age Ageing. 2018 Sep.
PMID: 29893779
Evaluates STOPP/START-based electronic decision support in inpatient settings.
[RCT · 2021]
Blum MR, Sallevelt BTGM, Spinewine A et al. (OPERAM Trial).
Optimizing Therapy to Prevent Avoidable Hospital Admissions in Multimorbid Older Adults: cluster randomised controlled trial. BMJ. 2021 Jul.
PMID: 34257088
Major multicentre RCT applying STOPP/START-guided medication review; tests impact on hospital admissions.
Medication Chart Review / Combined Criteria
[Systematic Review + Meta-Analysis · 2024]
Carollo M, Crisafulli S, Vitturi G et al.
Clinical impact of medication review and deprescribing in older inpatients: A systematic review and meta-analysis. J Am Geriatr Soc. 2024 Oct.
PMID: 38822740
Directly addresses structured medication review outcomes (falls, mortality, rehospitalisation) in elderly inpatients.
[Systematic Review + Meta-Analysis · 2025]
Persaud N, Workentin A, Rizvi A et al.
Interventions to Address Potentially Inappropriate Prescribing for Older Primary Care Patients: A Systematic Review and Meta-Analysis. JAMA Netw Open. 2025 Jun.
PMID: 40577011
Most recent (2025) high-quality evidence on PIP reduction interventions in primary care elderly.
[Systematic Review + Meta-Analysis · 2025]
Linsky AM, Motala A, Booth M et al.
Deprescribing in Community-Dwelling Older Adults: A Systematic Review and Meta-Analysis. JAMA Netw Open. 2025 May.
PMID: 40338546
Focuses on deprescribing as an actionable outcome of medication chart review.
[Systematic Review + Meta-Analysis · 2025]
Skains RM, Hayes JM, Selman K et al.
Emergency Department Programs to Support Medication Safety in Older Adults: A Systematic Review and Meta-Analysis. JAMA Netw Open. 2025 Mar.
PMID: 40067297
Psychotropic-Specific PIP
[Systematic Review + Meta-Analysis · 2024]
Corvaisier M, Brangier A, Annweiler C et al.
Preventable or potentially inappropriate psychotropics and adverse health outcomes in older adults: systematic review and meta-analysis. J Nutr Health Aging. 2024 Apr.
PMID: 38341965
Quantifies harms (falls, fractures, cognitive decline) linked to Beers-listed psychotropics.
Regional Prevalence
[Systematic Review + Meta-Analysis · 2024]
Alshehri AA, Khawagi WY, Alqahtani SM et al.
Prevalence of Potentially Inappropriate Prescribing in Older Adults in Gulf Cooperation Council Countries: A Systematic Review and Meta-Analysis. J Epidemiol Glob Health. 2024 Dec.
PMID: 39621251
Quick Summary Table
| PMID | Tool Used | Setting | Year | Tier |
|---|
| 34378710 | Beers | General | 2021 | Systematic Review |
| 29589066 | Beers + STOPP/START (19 tools) | General | 2018 | Systematic Review |
| 37531105 | Beers + STOPP | Global | 2023 | SR + Meta-Analysis |
| 26990017 | STOPP/START | General | 2016 | SR + Meta-Analysis |
| 29893779 | STOPP/START (CDS) | Inpatient | 2018 | SR + Meta-Analysis |
| 34257088 | STOPP/START | Hospital | 2021 | RCT |
| 38822740 | Medication review | Inpatient | 2024 | SR + Meta-Analysis |
| 40577011 | PIP interventions | Primary care | 2025 | SR + Meta-Analysis |
| 40338546 | Deprescribing | Community | 2025 | SR + Meta-Analysis |
| 38341965 | Beers psychotropics | General | 2024 | SR + Meta-Analysis |
All articles are indexed on PubMed. Click any PMID link to access the abstract directly. If you need full APA/BibTeX citations or abstracts for any specific paper, just ask.