Now I have rich material from three authoritative surgical references. Here is a complete set of operative notes for epidermal cyst excision:
Epidermal Cyst - Operative Notes
Preoperative
Diagnosis: Epidermal inclusion cyst (epidermoid / sebaceous cyst)
Indications for surgery:
- Cosmetic concern or symptomatic enlargement
- Recurrent inflammation or prior rupture
- Rapidly enlarging lesion (to exclude rare malignant transformation - SCC, BCC, melanoma have been reported)
- Curative excision after resolution of acute infection (I&D performed as a separate prior procedure if acutely infected)
Consent: Risks discussed - recurrence (especially if cyst wall is incomplete), haematoma, wound infection, scarring, damage to surrounding structures.
Anaesthesia
- Local infiltration anaesthesia - standard for solitary lesions
- General anaesthesia - if multiple cysts are to be removed at once
- Agent: 1% lidocaine +/- adrenaline (1:100,000) infiltrated circumferentially around the cyst
Patient Position
Dependent on site. Supine for facial/trunk lesions; prone for back/posterior lesions. Ensure adequate exposure and lighting.
Procedure
1. Preparation
- Skin cleaned with antiseptic (chlorhexidine or betadine)
- Sterile draping applied
2. Skin Incision
- An elliptical incision is made centered on and including the punctum (the comedo-like central pore that identifies the cyst)
- The ellipse is made longer than the cyst and approximately one-third of the cyst diameter in width
- The ellipse of skin with the punctum is excised, serving as a handle and preventing cyst rupture
- Incision carried down to the level of the cyst capsule
3. Dissection and Cyst Enucleation
- The line of cleavage is identified between the cyst wall and surrounding subcutaneous tissue
- If the cyst has never been infected, it shells out readily with blunt and sharp dissection
- A suture may be looped through the cyst and overlying skin to provide traction during dissection
- The cyst is freed circumferentially, avoiding rupture
4. If Cyst Ruptures
- Express all contents and meticulously excise all cyst wall fragments - retained epithelium causes recurrence
- A curette may be used to scrape out residual fragments of the cyst wall
- Alternatively, the lining can be eradicated by cauterisation with 20% trichloroacetic acid
5. Cyst Wall (Capsule)
- The pearly white capsule is the key structure - it must be completely removed to prevent recurrence
- If the cyst was previously infected (inflamed, adherent), it will be more firmly adherent and require careful sharp dissection
- For infected cysts: a two-stage approach is acceptable - I&D acutely, then formal capsule excision at a subsequent visit once inflammation has resolved. Alternatively, complete excision can be performed at the initial operation.
6. Inspection of Wound
- Confirm complete removal of capsule and any "daughter" cysts
- Achieve haemostasis with diathermy or pressure
- Irrigate wound with saline
7. Closure
- Dead space is obliterated with interrupted absorbable deep sutures (e.g. 3-0 Vicryl) if required
- Skin closed with interrupted non-absorbable sutures (e.g. 3-0 Prolene or 4-0 Nylon) or subcuticular absorbable suture depending on site and surgeon preference
- Dressing applied
Postoperative
- Wound check at 48-72 hours
- Suture removal at 7-10 days (face) or 10-14 days (trunk/extremities)
- Specimen sent for histology - mandatory if any atypical features (rapid enlargement, hard consistency, ulceration)
- Advise patient: recurrence is possible if any capsule remains; report any new swelling or signs of infection
Alternative / Minimally Invasive Technique
- A 4 mm punch biopsy tool can be used to make a small circular incision over the punctum, and the cyst contents and wall are expressed or retrieved through this small opening - suitable for smaller, non-infected cysts with a clear punctum
- This results in a smaller scar but carries a higher risk of incomplete removal
Notes on Infected / Inflamed Cysts
Rupture induces a vigorous foreign body reaction causing the cyst to adhere firmly to surrounding tissue, making clean dissection difficult. Two options:
- Primary resection at initial presentation - faster healing, fewer pain days, less scarring (supported by an RCT by Kitamura et al., 71 patients)
- Staged approach - I&D first, formal excision once inflammation has fully settled
Cultures from infected epidermal cysts are usually negative - this is a chemical/foreign body reaction, not true bacterial infection. Antibiotics are not routinely required unless cellulitis is present. MRSA should be considered in endemic areas.
Sources: Pye's Surgical Handicraft, 22nd Ed. | Roberts and Hedges' Clinical Procedures in Emergency Medicine | Fischer's Mastery of Surgery, 8th Ed. | Andrews' Diseases of the Skin, Clinical Dermatology