Increase platelets in which diseases
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thrombocytosis AND causes
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Merck Manual reactive thrombocytosis causes essential thrombocythemia
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Increased platelet count (thrombocytosis) occurs in:
Primary causes: myeloproliferative neoplasms
- Essential thrombocythemia
- Polycythemia vera
- Chronic myeloid leukemia (CML)
- Primary myelofibrosis (agnogenic myeloid metaplasia)
Secondary or reactive causes
- Iron-deficiency anemia
- Acute blood loss or hemorrhage
- Chronic infection or inflammation, such as tuberculosis, rheumatoid arthritis, inflammatory bowel disease
- Solid cancers/malignancies
- After splenectomy
- Rebound after recovery from bone marrow suppression, for example after chemotherapy
Reactive thrombocytosis accounts for most cases. Henry's Clinical Diagnosis and Management by Laboratory Methods, p. 908.
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