Make 15 minutes ppt on topic Genetics anatomy and biochemistry of behavioural science
Genetics Anatomy Biochemistry BehaviouralScience
Presentation · PPTX
| Slide | Content |
|---|---|
| 1 | Title slide |
| 2 | Lecture roadmap (4-quadrant overview) |
| 3 | Section divider — Genetics |
| 4 | Heritability & twin studies (ACE model + heritability table for 6 disorders) |
| 5 | GWAS, polygenic risk scores, and 5 candidate gene cards (COMT, MAOA, 5-HTTLPR, DISC1, BDNF) |
| 6 | Epigenetics + Gene×Environment interaction (Caspi studies, NR3C1, diathesis-stress) |
| 7 | Section divider — Neuroanatomy |
| 8 | Limbic system (amygdala, hippocampus, ACC, hypothalamus — colour-coded cards) |
| 9 | PFC (DLPFC, VMPFC, OFC) + Basal ganglia (NAc, striatum, DBS targets) |
| 10 | HPA axis cascade diagram + chronic stress effects on brain |
| 11 | Section divider — Biochemistry |
| 12 | Monoamines: DA, 5-HT, NE — synthesis pathways, circuits, behaviours, disorders |
| 13 | Receptor pharmacology (ionotropic vs GPCR) + second messenger cascades (cAMP/PKA, MAPK, mTOR) |
| 14 | Section divider — Clinical Integration |
| 15 | 4-disorder integration table (Schizophrenia, MDD, Anxiety/PTSD, Addiction) |
| 16 | Epigenetics as therapeutic target (HDAC inhibitors, DNMT inhibitors, BET inhibitors, miRNA) |
| 17 | 5 key take-aways |
| 18 | References (Kaplan & Sadock, Stahl, Emery's, Blumenfeld, Caspi, PGC Lancet 2013) |
| 19 | Closing quote slide |
Create a companion PDF with detailed neurotransmitter receptor diagrams
Neurotransmitter Receptor Diagrams CompanionPDF
PDF Document · PDF
| Fig. | Diagram | Key Features |
|---|---|---|
| 1 | GPCR / 7-TM Receptor | All 7 helices labeled, ECL/ICL loops, ligand pocket, Gα/β/γ subunits, effector arrow |
| 2 | NMDA Receptor | 4-subunit tetramer, Mg²⁺ block in pore, glutamate/glycine/Zn²⁺/PCP binding sites, Ca²⁺ influx → LTP |
| 3 | GABA-A / Benzodiazepine Complex | 5-subunit pentamer (2α·2β·1γ), GABA site at α/β, BDZ site at α/γ, barbiturate TM site, Cl⁻ pore |
| 4 | Dopamine D1 vs D2 Signalling | Side-by-side cascades: D1→Gs→AC→cAMP→PKA→CREB vs D2→Gi→AC↓→K⁺↑/Ca²⁺↓ |
| 5 | Serotonin Receptor Map | All 8 major subtypes arranged by Gi/Gq/Gs/ionotropic class with clinical links |
| 6 | Norepinephrine α1/α2/β1/β2 | Receptor subtypes from locus coeruleus, second messenger cascades, drug annotations |
| 7 | Second Messenger Cascades | Three parallel pathways: cAMP/PKA, Gq/PKC, MAPK/ERK — all converging on gene expression |
| 8 | Chemical Synapse Anatomy | Full lifecycle: vesicle packaging → exocytosis → receptor binding → DAT/SERT reuptake → MAO degradation → autoreceptor feedback |
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