Ultrasound (USG) in Gynecology and Obstetrics - A Complete Guide
References: Creasy & Resnik's Maternal-Fetal Medicine (Principles and Practice); Berek & Novak's Gynecology; Grainger & Allison's Diagnostic Radiology; ISUOG Practice Guidelines 2019; D.C. Dutta's Textbook of Obstetrics (cited by principle); Williams Obstetrics (cited by principle)
PART 1: FUNDAMENTALS - HOW TO READ A GYNECOLOGICAL/OBSTETRIC USG
The Ultrasound Report: What to Look For First
Every obstetric USG report must contain (per Creasy & Resnik's MFM, Chapter 16):
- Patient identifying information
- Date of examination
- Indication for the procedure
- Type of examination (transabdominal / transvaginal)
- Gestational age by established dates
- Number of fetuses and chorionicity (if multiple)
- Fetal biometry with predicted gestational age
- Principal findings (normal, abnormal, and poorly visualized structures)
- Differential diagnosis for any abnormalities
- Recommendations for management
Probe Types and Patient Preparation
| Approach | Probe | Bladder | Best Used For |
|---|
| Transabdominal (TAS) | Curvilinear (3-5 MHz) | Full | 2nd/3rd trimester, general pelvic survey |
| Transvaginal (TVS) | Endocavitary (5-10 MHz) | Empty | 1st trimester, cervical length, adnexa |
| Translabial | Curvilinear | Moderately full | Cervical os visualization |
Rule: TVS gives better resolution for early pregnancy (< 8 weeks), obese patients, and detailed adnexal assessment. TAS is preferred once the uterus rises above the pelvic brim (after ~12 weeks).
Basic Echogenicity Key (How structures appear on screen)
| Appearance | Term | Examples |
|---|
| Bright white | Hyperechoic / Echogenic | Bone, calcifications, gas |
| Mid-gray | Isoechoic | Normal myometrium, liver |
| Dark gray | Hypoechoic | Muscle, solid masses |
| Jet black | Anechoic | Fluid, blood, cysts |
| Mixed | Heterogeneous | Complex masses, fibroids with degeneration |
The "posterior acoustic enhancement" sign: seen behind purely fluid-filled cysts - the area behind a cyst appears brighter than surrounding tissue. This confirms a truly cystic (fluid-filled) structure.
PART 2: OBSTETRIC USG - THE THREE TRIMESTERS
OBSTETRIC USG POCKET REFERENCE
FIRST TRIMESTER USG (Weeks 4-13+6)
Goal: Confirm intrauterine pregnancy, gestational age, cardiac activity, number of fetuses, nuchal translucency.
What you see in sequence (using TVS):
| Gestational Age | Structure Visible | Size/Notes |
|---|
| 4-4.5 weeks | Gestational Sac (GS) | Anechoic, intradecidual sign |
| 5 weeks | Yolk Sac (YS) | Round, echogenic ring, 3-5 mm |
| 6 weeks | Fetal Pole (FP) | Adjacent to yolk sac |
| 6-7 weeks | Cardiac Activity | Must confirm when CRL ≥ 7 mm |
| 11-13+6 weeks | Nuchal Translucency (NT) | < 3 mm normal |
Key measurements:
- Mean Sac Diameter (MSD) = (Length + Width + Height) ÷ 3 - used before CRL is measurable
- Crown-Rump Length (CRL) = most accurate dating measurement in 1st trimester (±3-5 days)
- Nuchal Translucency (NT) - measured at 11-13+6 weeks; > 3 mm raises risk of aneuploidy
Discriminatory zone for hCG:
- TVS: Gestational sac should be visible when hCG > 1,000-2,000 mIU/mL
- TAS: Gestational sac visible when hCG > 3,000-5,000 mIU/mL
Diagnostic criteria for early pregnancy failure (Creasy & Resnik):
- CRL ≥ 7 mm with NO cardiac activity = missed abortion
- MSD ≥ 25 mm with NO embryo = anembryonic pregnancy (blighted ovum)
- No embryo with heartbeat ≥ 2 weeks after GS seen without yolk sac
- No embryo with heartbeat ≥ 11 days after GS seen with yolk sac
SECOND TRIMESTER USG - THE ANATOMY SCAN (Weeks 18-22)
This is the "standard" anatomy scan. Per Creasy & Resnik's MFM (Box 16.3), the mid-trimester anatomy scan (CPT 76805) must assess:
HEAD AND FACE:
- Cranial bones (should be bright, smooth)
- Falx cerebri (midline bright linear echo)
- Cavum septi pellucidi (CSP)
- Thalami
- Lateral ventricles (< 10 mm = normal)
- Cerebellum ("banana" shape = normal; "banana sign" absent = spina bifida suspect)
- Cisterna magna (2-10 mm = normal)
- Orbits, facial profile, upper lip, nasal bone
USG Image: Fetal BPD/HC Measurement (18 weeks)
Fig. 16.1 - Head circumference (HC) and biparietal diameter (BPD) measurement at 18w. BPD 4.03 cm = GA 18w2d. HC 15.09 cm = GA 18w1d. OFD = occipital-frontal diameter. (Creasy & Resnik's MFM)
USG Image: Posterior Fossa - Cerebellum, Cisterna Magna, Nuchal Fold
Fig. 16.5 - Posterior fossa view: Cerebellum 1.71 cm (GA 18w0d), Cisterna magna 0.28 cm, Nuchal fold 3.18 mm - all within normal range. (Creasy & Resnik's MFM)
USG Image: Fetal Nose and Lips
Fig. 16.8 - Fetal face: nose and lips. Normal intact upper lip (rules out cleft lip). (Creasy & Resnik's MFM)
THORAX:
- Four-chamber view of heart (heart apex should point LEFT at ~45° from spine)
- Cardiac axis
- Left ventricular outflow tract (LVOT) - aorta arising from LV
- Right ventricular outflow tract (RVOT) - pulmonary artery arising from RV
- Lung parenchyma (should be slightly echogenic)
USG Image: Fetal Four-Chamber Heart View
Fig. 16.10 - Four-chamber heart in diastole (A) and systole (B). RV = right ventricle, LV = left ventricle, RA = right atrium, LA = left atrium, Desc Ao = descending aorta. Both ventricles should be roughly equal in size. (Creasy & Resnik's MFM)
ABDOMEN:
- Stomach (anechoic bubble in left upper quadrant - confirms swallowing)
- Intestines
- Abdominal circumference (AC) - measured at level of umbilical vein
- Kidneys (bilateral, pelvis < 4 mm)
- Bladder
- Umbilical cord insertion (normal vs omphalocele/gastroschisis)
SPINE AND EXTREMITIES:
- Spine in longitudinal and transverse views
- All four long bones (femur, tibia, fibula, humerus, radius, ulna)
- Hands and feet posture
PLACENTA, CORD, FLUID:
- Placenta location (anterior, posterior, fundal - note if low-lying)
- Umbilical cord (should have 2 arteries + 1 vein = 3 vessels)
- Amniotic Fluid Index (AFI) or Maximum Vertical Pocket (MVP)
- Normal AFI: 8-24 cm; Normal MVP: 2-8 cm
Standard Biometry Parameters (2nd/3rd trimester):
| Measurement | Abbreviation | What to Measure | Clinical Use |
|---|
| Biparietal diameter | BPD | Outer to inner table of skull at thalami | Gestational age |
| Head circumference | HC | Circumference of skull at BPD level | Age + growth |
| Abdominal circumference | AC | Circumference at liver + umbilical vein | Growth, IUGR detection |
| Femur length | FL | Length of ossified diaphysis | Age + skeletal dysplasia |
| Estimated fetal weight | EFW | Calculated from BPD, HC, AC, FL | Growth assessment |
THIRD TRIMESTER USG (Weeks 28-40)
Primary goals: Fetal growth, presentation, placenta, amniotic fluid, Doppler.
- Fetal presentation: Cephalic (vertex), breech, transverse, or oblique
- Fetal lie: Longitudinal, oblique, or transverse
- Placenta: Grade (Grannum 0-III), position (distance from os if low-lying)
- Amniotic fluid: AFI (< 5 = oligohydramnios; > 24 = polyhydramnios)
- Doppler studies: Umbilical artery, middle cerebral artery (MCA), ductus venosus
- Normal umbilical artery: forward diastolic flow
- Absent/reversed end-diastolic flow = fetal compromise
Fetal weight estimation (Hadlock formula): Uses BPD, HC, AC, FL - accurate to ±15%.
PART 3: GYNECOLOGICAL USG - NORMAL ANATOMY
Normal Uterus on USG
Transabdominal (full bladder required):
- Pear-shaped organ in pelvis
- Uterus size: length 7-8 cm, width 4-5 cm, AP diameter 4 cm (nulliparous)
- Myometrium: homogenous, medium echogenicity
- Endometrium appears as a bright echogenic line (varies with cycle phase)
Endometrial thickness by cycle phase:
| Phase | Thickness | Appearance |
|---|
| Menstrual | 2-4 mm | Thin, bright line |
| Proliferative (early) | 4-8 mm | Thin, echogenic |
| Proliferative (late) | 8-12 mm | Multilayered / trilaminar pattern |
| Secretory | 10-14 mm | Thickened, bright, homogeneous |
| Postmenopausal (normal) | < 4-5 mm | Thin bright line |
Normal ovary:
- Size: 3 x 2 x 2 cm (volume ~8 cc in reproductive age)
- Contains developing follicles (anechoic, round, 2-20 mm)
- Dominant follicle at ovulation: 18-25 mm
- Corpus luteum: thick-walled, with peripheral vascularity ("ring of fire" on Doppler)
PART 4: GYNECOLOGICAL PATHOLOGIES ON USG
1. UTERINE FIBROIDS (Leiomyoma)
USG appearance:
- Well-defined, hypoechoic to heterogeneous, rounded masses in or around the uterus
- May contain calcifications (bright echoes with shadowing)
- Posterior acoustic shadowing is common
- Uterus is usually enlarged and irregular in contour
Types and location:
- Intramural: within myometrium (most common)
- Submucosal: bulges into endometrial cavity
- Subserosal: projects outward from uterine surface
- Pedunculated: on a stalk, may mimic adnexal mass
D.C. Dutta's Obstetrics principle: Fibroids causing submucosal distortion are most likely to cause abnormal uterine bleeding and should be carefully evaluated by TVS or sonohysterography.
2. OVARIAN CYSTS
The first image below is from a tubal ectopic pregnancy but illustrates the anechoic ring appearance of an adnexal cyst:
Bailey and Love's Surgery, Fig. 87.4 - Ultrasound image of a tubal ectopic pregnancy showing an anechoic cystic adnexal structure outside the uterus.
Classification of ovarian cysts on USG (Grainger & Allison's Diagnostic Radiology):
| Type | USG Appearance | Likely Diagnosis |
|---|
| Simple cyst | Anechoic, thin walls, posterior enhancement, no internal echoes | Follicular cyst, serous cystadenoma |
| Hemorrhagic cyst | Internal reticular ("fish-net") echoes, no flow on Doppler | Hemorrhagic corpus luteum |
| Complex cyst | Thick walls, internal septae, solid components | Endometrioma, dermoid, malignancy |
| Dermoid (teratoma) | Bright hyperechoic "tip-of-the-iceberg" appearance, shadowing, "Rokitansky nodule" | Benign mature teratoma |
| "Chocolate cyst" | Homogeneous, ground-glass low-level echoes | Endometrioma |
Risk of Malignancy Index (RMI) uses USG score (U), menopausal status (M), and CA-125:
- Multilocular cysts, bilateral masses, ascites, solid areas, metastases each raise the score
- RMI > 200 = high risk, refer to gynecologic oncologist
USG Image: Fetal Ovarian Cyst with Daughter Cyst (31 weeks)
Creasy & Resnik's MFM, Fig. 24.38 - Fetal ovarian cyst at 31w5d. Main cyst (large anechoic structure) with a daughter cyst (yellow arrow). This is a benign fetal ovarian cyst due to maternal/placental hormone stimulation. Most resolve postpartum.
3. ECTOPIC PREGNANCY
USG findings (Berek & Novak's Gynecology):
- Empty uterine cavity (no IUP visible)
- Adnexal mass separate from ovary ("tubal ring" sign)
- Free fluid in pouch of Douglas (hemoperitoneum)
- Live ectopic pregnancy: fetal cardiac activity outside uterus (pathognomonic)
Discriminatory zone: If hCG > 1,500-2,000 mIU/mL and TVS shows empty uterus = ectopic until proven otherwise.
Pseudogestational sac: Small central anechoic collection in uterus due to decidual reaction - does NOT have an echogenic ring (unlike true IUP); NO yolk sac inside.
4. MOLAR PREGNANCY (Hydatidiform Mole)
Complete mole:
- Classic "snowstorm" pattern - uterus filled with heterogeneous echogenic material with multiple small anechoic spaces (representing hydropic villi)
- No identifiable fetal parts or normal placenta
- Bilateral theca-lutein ovarian cysts (large, multi-septate)
- Markedly elevated hCG
Partial mole:
- Ratio of transverse to AP diameter of gestational sac > 1.5
- Abnormal fetal parts may be present (triploid fetus)
- Swiss cheese appearance of placenta
D.C. Dutta's principle: The snowstorm appearance on USG + markedly elevated hCG is pathognomonic of complete hydatidiform mole. TVS is more sensitive than TAS for early diagnosis.
5. PLACENTA PREVIA
Definition: Placenta implanted over or near the internal cervical os.
USG grading (per Creasy & Resnik/ISUOG):
- Complete previa: Placenta completely covers the internal os
- Partial previa: Placenta partially covers the os
- Marginal previa: Placental edge reaches the os
- Low-lying placenta: Placental edge within 2 cm of os but not covering it
How to assess:
- TAS first; always confirm with TVS (full bladder on TAS may give false previa)
- Measure distance from placental edge to internal os in mm
- < 2 cm from os = low-lying; 0 cm or overlap = previa
- Remember: "Placental migration" - most low-lying placentas at 20 weeks migrate away by 34 weeks as the lower segment develops
6. PLACENTAL ABRUPTION
USG findings:
- Retroplacental hematoma: hypoechoic/anechoic area between placenta and uterine wall
- Subchorionic hematoma: collection under the chorion
- Marginal hematoma: at placental edge
- Note: USG sensitivity for abruption is only ~50% - diagnosis is primarily clinical. A NEGATIVE scan does NOT rule out abruption.
7. POLYCYSTIC OVARIAN SYNDROME (PCOS)
Rotterdam criteria (USG component):
- Ovarian volume > 10 cc (calculated as 0.523 × L × W × H)
- ≥ 12 follicles per ovary measuring 2-9 mm in diameter ("string of pearls" sign)
- Follicles arranged peripherally around an echogenic stroma
8. ENDOMETRIAL PATHOLOGY
| Condition | USG Finding |
|---|
| Endometrial polyp | Focal hyperechoic intrauterine mass, often with central vascular stalk on Doppler |
| Endometrial hyperplasia | Diffusely thickened, bright endometrium (> 4-5 mm postmenopausal) |
| Endometrial carcinoma | Irregular, heterogeneous, thickened endometrium; may invade myometrium |
| Asherman's syndrome | Thin/absent endometrium, intrauterine synechiae |
9. ABNORMAL EARLY PREGNANCY / MISCARRIAGE
| Type | USG Finding |
|---|
| Threatened abortion | IUP present, cardiac activity present, small subchorionic hemorrhage may be seen |
| Incomplete abortion | Heterogeneous echogenic material in uterine cavity, open os |
| Complete abortion | Empty uterine cavity (endometrium < 15 mm) |
| Missed abortion | GS/embryo present, NO cardiac activity (CRL ≥ 7 mm) |
| Blighted ovum | GS present (MSD ≥ 25 mm), no embryo |
PART 5: KEY USG VIEWS IN SUMMARY
The Obstetric USG Pocket Reference
(As illustrated in the POCUS 101 reference card above)
1st Trimester Checklist:
- Confirm IUP (gestational sac in uterus)
- Gestational dating: MSD, then CRL
- Yolk sac and fetal pole
- Cardiac activity
- Nuchal translucency (at 11-13+6 wks)
2nd/3rd Trimester Checklist:
- Fetal heart rate
- Fetal lie and presentation
- Amniotic fluid volume (MVP/AFI)
- Fetal biometrics: BPD, HC, AC, femur length
- Evaluate placenta (location, appearance, cord insertion)
- Detailed anatomy (2nd trimester)
KEY REFERENCE SUMMARY
| Topic | Source |
|---|
| Types of obstetric USG examinations, documentation, anatomy scan elements | Creasy & Resnik's Maternal-Fetal Medicine, Chapter 16 (CPT codes 76801-76816) |
| Detailed fetal anatomy images (figs. 16.1-16.38) | Creasy & Resnik's MFM, pp. 319-330 |
| Fetal anomalies: ovarian cysts, renal cysts, abdominal masses | Creasy & Resnik's MFM, Chapter 24, pp. 507-510 |
| Ovarian cyst classification, hemorrhagic cysts, transvaginal imaging | Grainger & Allison's Diagnostic Radiology, Chapter 7 |
| Ectopic pregnancy USG criteria | Berek & Novak's Gynecology, Chapter 9 |
| Fetal heart four-chamber view, LVOT, RVOT | Creasy & Resnik's MFM, pp. 325-327 |
| Fibroid, molar pregnancy, PCOS | D.C. Dutta's Textbook of Obstetrics (clinical principles) |
| Placenta previa classification | Creasy & Resnik's MFM; Williams Obstetrics 26th ed. |
| ISUOG biometry guidelines | ISUOG Clinical Standards Committee, Ultrasound Obstet Gynecol 2019;53:715-723 |
Important clinical note: USG findings must always be interpreted together with the clinical history, examination, and laboratory results (hCG, CA-125, etc.). A single USG finding in isolation is rarely diagnostic. Serial scans and Doppler studies add significantly to the diagnostic accuracy in both gynecological and obstetric practice.