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Give crisp and concise answer from latest edition of Harrison's medicine

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All 40 questions answered. Here's a quick summary of key answers:

MCQ Answer Key: 1-c, 2-a, 3-d, 4-b, 5-d, 6-c, 7-b, 8-a, 9-b, 10-d, 11-b, 12-a, 13-c, 14-d, 15-b, 16-c, 17-a, 18-b, 19-a (Paucibacillary = Rifampicin + Dapsone only), 20-a
High-yield points to remember:
  • Atypical pneumonia + hemolytic anemia = Mycoplasma (cold agglutinins)
  • Asthma PFT = decreased FEV1/FVC + reversibility (≥12% improvement post-bronchodilator)
  • Lichen Planus = 6 P's (Purple, Polygonal, Planar, Pruritic Papules + Plaques)
  • CURB-65: Confusion, Urea, Resp rate, BP, Age ≥65 - score ≥3 = hospitalize
  • Elapid bite = respiratory failure (neurotoxic); Viper = DIC/ARF (vasculotoxic)
  • Schober's test: Marks 5 cm below + 10 cm above S1 → normal if distance increases ≥5 cm on flexion
  • Anaphylaxis drug/dose: Epinephrine 0.3-0.5 mg of 1:1000 IM anterolateral thigh
  • Methanol antidote = Fomepizole (preferred over ethanol) + hemodialysis if severe
  • Delirium vs Dementia: acute/reversible/fluctuating vs insidious/irreversible/progressive
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