This composite medical image displays clinical signs of generalized edema (anasarca). Panel A is a clinical photograph of a patient's face showing significant facial edema, characterized by periorbital swelling, puffiness of the cheeks, and fullness of the soft tissues, leading to a narrowed appearance of the eyes. Panel B is an axial CT scan of the thorax demonstrating mild bilateral pleural effusion, visible as dependent, low-density crescentic fluid collections in the posterior pleural spaces (indicated by a white star). Panel C is an axial abdominal CT scan showing mild ascites, identified as low-density fluid surrounding abdominal viscera, with a white arrow specifically pointing to fluid in the perihepatic/paracolic gutter area. These findings collectively illustrate the multisystemic fluid accumulation associated with conditions like systemic capillary leak syndrome or profound hypoalbuminemia. The images are highly relevant for medical education concerning the physical and radiological manifestations of fluid overload and serous cavity effusions.

This set of clinical photographs illustrates a pediatric patient presenting with severe generalized edema (anasarca). Panel A displays a frontal view of an infant with significant swelling affecting the face, periorbital region, neck, trunk, and extremities. The skin appears tense, glossy, and exhibits areas of pallor and hyperpigmentation. Panels B and C demonstrate the physical examination for pitting edema on the patient's back. Panel B shows a clinician's thumb applying pressure to the edematous tissue, while Panel C reveals a deep, persistent indentation (pitting) remaining after the pressure is released. This clinical presentation is associated with systemic fluid overload or severe hypoalbuminemia, documented here in the context of an atypical parasitic infection. The images serve as a teaching tool for identifying the visual signs of gross edema and the technique for eliciting and documenting pitting in soft tissues.

This clinical photograph shows a young female patient in a supine position, illustrating the resolution phase of generalized edema (anasarca). The patient exhibits a visible reduction in swelling around the facial region, specifically the periorbital and lip areas, compared to a state of acute exacerbation. Clinical support is evident via a nasal cannula for supplemental oxygen and a peripheral intravenous (IV) catheter secured on the dorsal aspect of the left hand. Notable dermatological findings include patches of hypopigmentation or depigmentation on the right forearm and wrist. The image serves as an educational representation of the clinical response to corticosteroid therapy in a pediatric patient with systemic swelling. The patient's upper extremities show improved anatomical definition in the fingers and wrists, indicative of successful diuresis or resolution of interstitial fluid accumulation. The image captures the patient's status post-treatment for progressive body swelling and dysphagia, demonstrating partial recovery of normal tissue contours.

This clinical photograph displays an infant in a supine position, demonstrating generalized edema (anasarca) and features suggestive of Cushingoid facies. The patient exhibits significant facial puffiness with full, rounded cheeks and obscured facial contours, characteristic of 'moon facies.' There is evidence of generalized swelling throughout the upper and lower extremities, with visible skin distention and increased circumference of the limbs. The skin appears taut and smooth over the edematous areas. Clinical markers of a medical setting are present, including pink identification bands on the right wrist and ankle, and a white bandage on the left hand. The image serves as an educational illustration of systemic fluid retention and physical manifestations of hypercortisolism in a pediatric patient, likely in the context of iatrogenic Cushing syndrome. The infant is shown on a hospital bed, and the photograph is focused on the morphology and distribution of the edema across the entire body.