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First test to characterize an adnexal/ovarian mass:
Transvaginal pelvic ultrasound with Doppler.
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Best scan for staging once cancer is suspected or confirmed:
Contrast-enhanced CT of the chest, abdomen, and pelvis.
CT best evaluates peritoneal/omental spread, ascites, lymph nodes, liver and other distant metastases, and helps determine whether primary debulking surgery appears feasible. Grainger & Allison’s Diagnostic Radiology, block 7, lines 530-537.
MRI pelvis is mainly a problem-solving test when ultrasound is indeterminate or better local characterization of an adnexal mass is needed.
FDG PET-CT is not routine for initial preoperative staging, but can help in suspected recurrence or equivocal CT/MRI findings. A 2024 meta-analysis comparing CT and PET-CT for advanced ovarian-cancer staging is indexed as
PMID 38523146.