How much oxytocin used in pph and how iv or im ?
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WHO postpartum haemorrhage oxytocin treatment dosage IV infusion IM 2025
For treatment of postpartum hemorrhage (PPH) due to uterine atony:
- Oxytocin 10 IU IV, diluted and given slowly over 1-2 minutes. Do not give as a rapid IV push because it can cause hypotension.
- Then give an IV infusion: 10-20 IU in crystalloid fluid over about 4 hours, titrated to uterine tone and ongoing bleeding.
If IV access is not immediately available:
- Oxytocin 10 IU IM can be given while IV access is obtained.
Some protocols use 20-40 IU in 1 L normal saline/Ringer's lactate as an IV infusion. Follow your hospital's PPH protocol where available. WHO PPH guidance notes that 10 IU IV is commonly used initially, followed by 10-20 IU infusion if needed.
PPH is an emergency: simultaneously do uterine massage, assess for retained tissue/trauma/coagulopathy, obtain help, resuscitate, and give tranexamic acid early when indicated. If bleeding continues despite oxytocin, additional uterotonics and escalation are needed.
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