from pptx import Presentation
from pptx.util import Inches, Pt, Emu
from pptx.dml.color import RGBColor
from pptx.enum.text import PP_ALIGN, MSO_ANCHOR
from pptx.enum.shapes import MSO_SHAPE
from io import BytesIO

# Color Palette - Medical/Clinical theme
C_DARK_BLUE   = RGBColor(0x1A, 0x3A, 0x6B)   # deep navy
C_MED_BLUE    = RGBColor(0x27, 0x5E, 0xA8)   # accent blue
C_LIGHT_BLUE  = RGBColor(0xD9, 0xEA, 0xFF)   # slide bg tint
C_TEAL        = RGBColor(0x00, 0x87, 0x9B)   # section accent
C_ORANGE      = RGBColor(0xE8, 0x6B, 0x2C)   # highlight
C_WHITE       = RGBColor(0xFF, 0xFF, 0xFF)
C_LIGHT_GREY  = RGBColor(0xF2, 0xF5, 0xFB)
C_TEXT        = RGBColor(0x1C, 0x1C, 0x2E)
C_SUBTEXT     = RGBColor(0x44, 0x55, 0x77)

prs = Presentation()
prs.slide_width  = Inches(13.333)
prs.slide_height = Inches(7.5)
blank = prs.slide_layouts[6]

# ─────────────────────────────────────────
# Helper functions
# ─────────────────────────────────────────
def set_bg(slide, color):
    bg = slide.background
    bg.fill.solid()
    bg.fill.fore_color.rgb = color

def add_rect(slide, left, top, width, height, fill_color, line_color=None, line_width=None):
    shape = slide.shapes.add_shape(MSO_SHAPE.RECTANGLE,
        Inches(left), Inches(top), Inches(width), Inches(height))
    shape.fill.solid()
    shape.fill.fore_color.rgb = fill_color
    if line_color:
        shape.line.color.rgb = line_color
        if line_width:
            shape.line.width = Pt(line_width)
    else:
        shape.line.fill.background()
    return shape

def add_text(slide, text, left, top, width, height,
             font_name="Calibri", size=18, bold=False, italic=False,
             color=C_TEXT, align=PP_ALIGN.LEFT, v_anchor=MSO_ANCHOR.TOP,
             wrap=True):
    tb = slide.shapes.add_textbox(Inches(left), Inches(top), Inches(width), Inches(height))
    tf = tb.text_frame
    tf.word_wrap = wrap
    tf.vertical_anchor = v_anchor
    tf.margin_left = 0; tf.margin_right = 0
    tf.margin_top = Pt(2); tf.margin_bottom = 0
    p = tf.paragraphs[0]
    p.alignment = align
    run = p.add_run()
    run.text = text
    run.font.name = font_name
    run.font.size = Pt(size)
    run.font.bold = bold
    run.font.italic = italic
    run.font.color.rgb = color
    return tf

def add_bullet_para(tf, text, size=15, bold=False, color=C_TEXT, indent_level=0, space_before=4):
    p = tf.add_paragraph()
    p.level = indent_level
    p.alignment = PP_ALIGN.LEFT
    p.space_before = Pt(space_before)
    # bullet character
    run = p.add_run()
    bullet = "  • " if indent_level == 0 else "       – "
    run.text = bullet + text
    run.font.name = "Calibri"
    run.font.size = Pt(size)
    run.font.bold = bold
    run.font.color.rgb = color
    return p

def section_header_bar(slide, title, accent_color=C_MED_BLUE):
    """Top bar with section title"""
    add_rect(slide, 0, 0, 13.333, 1.1, accent_color)
    add_text(slide, title, 0.5, 0.1, 12.3, 0.9,
             font_name="Calibri", size=34, bold=True,
             color=C_WHITE, align=PP_ALIGN.LEFT, v_anchor=MSO_ANCHOR.MIDDLE)

def accent_bar(slide, left=0, top=1.1, width=13.333, height=0.06, color=C_ORANGE):
    add_rect(slide, left, top, width, height, color)


# ═══════════════════════════════════════════════════════════════
# SLIDE 1 — TITLE SLIDE
# ═══════════════════════════════════════════════════════════════
slide = prs.slides.add_slide(blank)
set_bg(slide, C_DARK_BLUE)

# Decorative left panel
add_rect(slide, 0, 0, 4.5, 7.5, C_MED_BLUE)
add_rect(slide, 0, 0, 0.18, 7.5, C_ORANGE)

# Title area
add_text(slide, "STURGE-WEBER", 5.0, 1.6, 7.8, 1.2,
         size=48, bold=True, color=C_WHITE, align=PP_ALIGN.LEFT)
add_text(slide, "SYNDROME", 5.0, 2.7, 7.8, 1.0,
         size=48, bold=True, color=C_ORANGE, align=PP_ALIGN.LEFT)

# Subtitle
add_text(slide, "A Neurocutaneous Disorder", 5.0, 3.8, 7.8, 0.5,
         size=20, italic=True, color=RGBColor(0xB8, 0xD4, 0xFF), align=PP_ALIGN.LEFT)

# Divider
add_rect(slide, 5.0, 4.4, 7.5, 0.05, C_ORANGE)

# Sub info
add_text(slide, "Etiology  |  Symptoms & Signs  |  Findings  |  Treatment",
         5.0, 4.6, 8.0, 0.5, size=14, color=RGBColor(0xB8, 0xD4, 0xFF),
         align=PP_ALIGN.LEFT)

# Left panel decorative text (vertical concept labels)
tb = slide.shapes.add_textbox(Inches(0.35), Inches(1.5), Inches(3.8), Inches(5.0))
tf = tb.text_frame; tf.word_wrap = True
for label, sz, bold in [
    ("Encephalotrigeminal\nAngiomatosis", 16, True),
    ("", 8, False),
    ("Phakomatosis", 13, False),
    ("", 8, False),
    ("GNAQ Mutation", 13, False),
    ("", 8, False),
    ("Port-Wine Stain", 13, False),
    ("", 8, False),
    ("Leptomeningeal\nAngioma", 13, False),
]:
    p = tf.add_paragraph()
    r = p.add_run(); r.text = label
    r.font.name = "Calibri"; r.font.size = Pt(sz)
    r.font.bold = bold; r.font.color.rgb = C_WHITE
    p.alignment = PP_ALIGN.CENTER


# ═══════════════════════════════════════════════════════════════
# SLIDE 2 — OVERVIEW / INTRODUCTION
# ═══════════════════════════════════════════════════════════════
slide = prs.slides.add_slide(blank)
set_bg(slide, C_LIGHT_GREY)
section_header_bar(slide, "Overview", C_DARK_BLUE)
accent_bar(slide)

# Two column layout
# Left box
add_rect(slide, 0.4, 1.3, 5.8, 5.8, C_WHITE)
add_rect(slide, 0.4, 1.3, 5.8, 0.45, C_TEAL)
add_text(slide, "What is Sturge-Weber Syndrome?", 0.5, 1.3, 5.6, 0.45,
         size=14, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)

tb_left = slide.shapes.add_textbox(Inches(0.55), Inches(1.9), Inches(5.5), Inches(5.0))
tf_l = tb_left.text_frame; tf_l.word_wrap = True
for txt in [
    "Rare congenital neurocutaneous (phakomatosis) disorder",
    "Also known as Encephalotrigeminal Angiomatosis",
    "Characterized by capillary-venous malformations affecting skin, brain, and eyes",
    "Occurs sporadically in ~1 in 20,000–50,000 live births",
    "Affects males and females equally; no racial predilection",
    "Third most common neurocutaneous syndrome after neurofibromatosis and tuberous sclerosis",
    "Non-heritable; does not affect lifespan in mild cases",
]:
    add_bullet_para(tf_l, txt, size=13, color=C_TEXT)

# Right box
add_rect(slide, 6.8, 1.3, 6.1, 5.8, C_WHITE)
add_rect(slide, 6.8, 1.3, 6.1, 0.45, C_MED_BLUE)
add_text(slide, "Classic Triad", 6.9, 1.3, 5.9, 0.45,
         size=14, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)

# Three feature boxes
features = [
    ("1", "Port-Wine Stain (PWS)", "Facial capillary malformation in the\ndistribution of trigeminal nerve (V1)"),
    ("2", "Leptomeningeal Angioma", "Ipsilateral parieto-occipital\nleptomeningeal angiomatosis"),
    ("3", "Glaucoma", "Ipsilateral increased intraocular\npressure; choroidal hemangioma"),
]
for i, (num, title, desc) in enumerate(features):
    y_start = 1.9 + i * 1.75
    add_rect(slide, 6.95, y_start, 5.8, 1.5, C_LIGHT_BLUE)
    add_rect(slide, 6.95, y_start, 0.45, 1.5, C_ORANGE)
    add_text(slide, num, 6.95, y_start + 0.35, 0.45, 0.7,
             size=22, bold=True, color=C_WHITE, align=PP_ALIGN.CENTER)
    add_text(slide, title, 7.5, y_start + 0.1, 5.1, 0.4,
             size=13, bold=True, color=C_DARK_BLUE)
    add_text(slide, desc, 7.5, y_start + 0.55, 5.1, 0.8,
             size=11, color=C_SUBTEXT)


# ═══════════════════════════════════════════════════════════════
# SLIDE 3 — ETIOLOGY
# ═══════════════════════════════════════════════════════════════
slide = prs.slides.add_slide(blank)
set_bg(slide, C_LIGHT_GREY)
section_header_bar(slide, "Etiology", C_TEAL)
accent_bar(slide, color=C_ORANGE)

# Main content area
add_rect(slide, 0.4, 1.3, 12.5, 5.8, C_WHITE)

# Gene mutation box
add_rect(slide, 0.55, 1.5, 5.8, 2.5, C_LIGHT_BLUE)
add_rect(slide, 0.55, 1.5, 5.8, 0.4, C_MED_BLUE)
add_text(slide, "Genetic Basis", 0.65, 1.5, 5.6, 0.4,
         size=14, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)

tb = slide.shapes.add_textbox(Inches(0.65), Inches(2.0), Inches(5.6), Inches(2.0))
tf = tb.text_frame; tf.word_wrap = True
for txt in [
    "Somatic, postzygotic, gain-of-function mutation in GNAQ gene (chromosome 9q21)",
    "Recently, GNA11 gene variants also described with subtle phenotypic differences",
    "Activates Gαq-coupled signaling → aberrant endothelial cell proliferation → capillary-venous malformations",
    "Mutation is mosaic — not detectable on standard blood-based genetic testing",
    "Mutation timing during embryogenesis determines extent and distribution of involvement",
]:
    add_bullet_para(tf, txt, size=12, color=C_TEXT)

# Pathophysiology box
add_rect(slide, 0.55, 4.1, 5.8, 2.7, C_LIGHT_BLUE)
add_rect(slide, 0.55, 4.1, 5.8, 0.4, C_MED_BLUE)
add_text(slide, "Pathophysiology", 0.65, 4.1, 5.6, 0.4,
         size=14, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)

tb2 = slide.shapes.add_textbox(Inches(0.65), Inches(4.6), Inches(5.6), Inches(2.1))
tf2 = tb2.text_frame; tf2.word_wrap = True
for txt in [
    "Facial skin and brain share common embryologic neural crest progenitors",
    "Capillary-venous malformations impair venous drainage → cortical hypoperfusion → ischemia",
    "Leptomeningeal angioma leads to progressive cortical atrophy and calcification",
    "Hemosiderin deposition and impaired autoregulation contribute to neurologic decline",
]:
    add_bullet_para(tf2, txt, size=12, color=C_TEXT)

# Risk factors box
add_rect(slide, 6.8, 1.5, 5.8, 5.3, C_LIGHT_BLUE)
add_rect(slide, 6.8, 1.5, 5.8, 0.4, C_ORANGE)
add_text(slide, "Key Features & Risk Factors", 6.9, 1.5, 5.6, 0.4,
         size=14, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)

tb3 = slide.shapes.add_textbox(Inches(6.9), Inches(2.0), Inches(5.6), Inches(4.6))
tf3 = tb3.text_frame; tf3.word_wrap = True
for txt in [
    "Sporadic — NOT inherited; no family history pattern",
    "Occurs in utero during vascular development",
    "Port-wine stain of upper face + periorbital area → highest risk for brain involvement",
    "Only ~15% of people with upper facial nevus develop brain involvement",
    "Hemifacial, forehead, or medial facial PWS → increased risk of neurologic involvement",
    "8–20% of all facial port-wine nevi → neurological symptoms",
    "Bilateral brain involvement possible if bilateral facial PWS",
    "Glaucoma may occur even without neurological involvement",
]:
    add_bullet_para(tf3, txt, size=12, color=C_TEXT)


# ═══════════════════════════════════════════════════════════════
# SLIDE 4 — SYMPTOMS AND SIGNS
# ═══════════════════════════════════════════════════════════════
slide = prs.slides.add_slide(blank)
set_bg(slide, C_LIGHT_GREY)
section_header_bar(slide, "Symptoms and Signs", C_MED_BLUE)
accent_bar(slide, color=C_TEAL)

# Three system columns
systems = [
    ("CUTANEOUS", C_ORANGE, [
        "Port-wine stain (PWS/Nevus Flammeus)",
        "Pink-to-dark-purple facial birthmark",
        "Distribution: V1 (ophthalmic) branch of trigeminal nerve (forehead/eyelid)",
        "V2 and V3 may also be involved",
        "Present at birth; obvious from day 1",
        "Darkens and thickens with age",
        "Nodular appearance develops in older patients",
        "Soft-tissue overgrowth and facial asymmetry",
        "May involve oral mucosa and gingiva",
    ]),
    ("NEUROLOGICAL", C_MED_BLUE, [
        "Focal-onset epilepsy (most common; ~80% of neurologically involved)",
        "Often drug-resistant in >50% of patients",
        "Onset usually in first year of life",
        "Stroke-like episodes (31–46% of patients aged 2–22 yrs)",
        "Transient or permanent hemiparesis (contralateral to lesion)",
        "Hemianopia (visual field defect)",
        "Cognitive impairment / intellectual disability (50–66%)",
        "Headaches / migraines",
        "Behavioral and psychiatric problems",
        "Developmental delay",
    ]),
    ("OPHTHALMOLOGICAL", C_TEAL, [
        "Glaucoma (raised intraocular pressure)",
        "Can occur without neurologic involvement",
        "Buphthalmos (enlarged eye in infants)",
        "Choroidal hemangioma (ipsilateral)",
        "Blood in Schlemm canal on gonioscopy",
        "Progressive visual impairment / vision loss",
        "Episcleral venous engorgement",
        "Periodic ophthalmologic screening essential",
    ]),
]

for i, (sys_name, color, bullets) in enumerate(systems):
    x = 0.3 + i * 4.35
    add_rect(slide, x, 1.25, 4.1, 5.95, C_WHITE)
    add_rect(slide, x, 1.25, 4.1, 0.5, color)
    add_text(slide, sys_name, x + 0.1, 1.25, 3.9, 0.5,
             size=13, bold=True, color=C_WHITE, align=PP_ALIGN.CENTER, v_anchor=MSO_ANCHOR.MIDDLE)
    tb = slide.shapes.add_textbox(Inches(x + 0.1), Inches(1.85), Inches(3.85), Inches(5.2))
    tf = tb.text_frame; tf.word_wrap = True
    for txt in bullets:
        add_bullet_para(tf, txt, size=11.5, color=C_TEXT, space_before=3)


# ═══════════════════════════════════════════════════════════════
# SLIDE 5 — RELEVANT FINDINGS (Investigations)
# ═══════════════════════════════════════════════════════════════
slide = prs.slides.add_slide(blank)
set_bg(slide, C_LIGHT_GREY)
section_header_bar(slide, "Relevant Findings", RGBColor(0x5C, 0x27, 0x8F))
accent_bar(slide, color=C_ORANGE)

# Classification of findings
sections_data = [
    ("NEUROIMAGING (MRI — Gold Standard)", RGBColor(0x5C, 0x27, 0x8F), [
        "MRI with gadolinium contrast: best modality for intracranial vascular lesion",
        "Leptomeningeal enhancement (pial angioma) — ipsilateral parieto-occipital",
        "Progressive cortical atrophy on involved side",
        "Choroid plexus enlargement / asymmetry (early sensitive finding)",
        "Susceptibility-weighted imaging (SWI) + contrast FLAIR: best for pial vascular abnormalities",
        "Cortical calcification: 'tram-track' / 'trolley-track' pattern (often absent in infants)",
        "Abnormal white matter signal; cerebral hemiatrophy in advanced cases",
        "Cortical T1 hyperintense signal (calcium deposition)",
    ]),
    ("CT SCAN", C_TEAL, [
        "Demonstrates 'tram-track' cortical calcifications (double contour along cerebral gyri)",
        "Better than MRI for calcification detection",
        "Less sensitive than MRI for early or subtle vascular changes",
    ]),
    ("EEG", C_MED_BLUE, [
        "Focal slowing and epileptiform discharges over affected hemisphere",
        "Background asymmetry",
        "Useful to guide anticonvulsant therapy",
        "Obtained in all patients with neurological involvement",
    ]),
]

y_cur = 1.35
for sec_title, color, items in sections_data:
    add_rect(slide, 0.35, y_cur, 12.6, 0.38, color)
    add_text(slide, sec_title, 0.5, y_cur, 12.2, 0.38,
             size=12, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)
    y_cur += 0.38
    tb = slide.shapes.add_textbox(Inches(0.5), Inches(y_cur), Inches(12.4), Inches(len(items) * 0.32))
    tf = tb.text_frame; tf.word_wrap = True
    for item in items:
        add_bullet_para(tf, item, size=12, color=C_TEXT, space_before=2)
    y_cur += len(items) * 0.32 + 0.2

# Bottom row: Ophthalmology + Genetics
add_rect(slide, 0.35, y_cur, 6.1, 0.38, C_ORANGE)
add_text(slide, "OPHTHALMOLOGICAL ASSESSMENT", 0.5, y_cur, 5.9, 0.38,
         size=12, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)
tb_o = slide.shapes.add_textbox(Inches(0.5), Inches(y_cur + 0.38), Inches(5.8), Inches(1.0))
tf_o = tb_o.text_frame; tf_o.word_wrap = True
for txt in [
    "Intraocular pressure measurement (every 3 months in first year, yearly thereafter)",
    "Gonioscopy: blood in Schlemm canal (pathognomonic sign)",
    "Fundus exam: choroidal hemangioma",
]:
    add_bullet_para(tf_o, txt, size=11.5, color=C_TEXT, space_before=2)

add_rect(slide, 6.85, y_cur, 5.85, 0.38, RGBColor(0x27, 0x6A, 0x47))
add_text(slide, "CLASSIFICATION (Roach Scale)", 7.0, y_cur, 5.6, 0.38,
         size=12, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)
tb_r = slide.shapes.add_textbox(Inches(7.0), Inches(y_cur + 0.38), Inches(5.6), Inches(1.0))
tf_r = tb_r.text_frame; tf_r.word_wrap = True
for txt in [
    "Type I: Facial PWS + leptomeningeal angioma (with or without glaucoma)",
    "Type II: Facial PWS alone + glaucoma; NO brain involvement",
    "Type III: Isolated leptomeningeal angioma; NO facial PWS",
]:
    add_bullet_para(tf_r, txt, size=11.5, color=C_TEXT, space_before=2)


# ═══════════════════════════════════════════════════════════════
# SLIDE 6 — TREATMENT
# ═══════════════════════════════════════════════════════════════
slide = prs.slides.add_slide(blank)
set_bg(slide, C_LIGHT_GREY)
section_header_bar(slide, "Treatment", RGBColor(0x0D, 0x6E, 0x3E))
accent_bar(slide, color=C_ORANGE)

treatment_cols = [
    ("NEUROLOGICAL\nMANAGEMENT", RGBColor(0x1A, 0x3A, 0x6B), [
        "Antiepileptic drugs (AEDs) — first-line for seizures",
        "Common agents: valproate, levetiracetam, oxcarbazepine",
        "Seizures are drug-resistant in >50% → surgical evaluation",
        "Focal cortical resection or hemispherectomy for refractory epilepsy",
        "Early seizure control → better cognitive outcomes",
        "Low-dose aspirin (adults) to reduce stroke-like episodes",
        "(Caution: aspirin not recommended in children routinely)",
        "Physical therapy for hemiparesis rehabilitation",
        "Neuropsychological support for cognitive/behavioral issues",
        "Special education programs for developmental delays",
    ]),
    ("OPHTHALMOLOGICAL\nMANAGEMENT", C_TEAL, [
        "Regular IOP monitoring (every 3 months in year 1, then annually)",
        "Topical antiglaucoma drops (beta-blockers, prostaglandin analogues, CAIs)",
        "Surgical intervention for refractory glaucoma",
        "Goniotomy or trabeculotomy in infants with buphthalmos",
        "Trabeculectomy / drainage implant devices if medical therapy fails",
        "Management of choroidal hemangioma (if symptomatic)",
        "Laser photocoagulation or PDT for choroidal hemangioma",
    ]),
    ("DERMATOLOGICAL\nMANAGEMENT", C_ORANGE, [
        "Pulsed-dye laser (PDL) — treatment of choice for PWS",
        "Reduces vascular staining; best results when started early",
        "Multiple sessions typically required",
        "Sirolimus (rapamycin) — emerging therapy",
        "mTOR inhibitor; reduces soft tissue overgrowth and capillary discoloration",
        "Also shown to reduce IOP as added benefit",
        "Cosmetic camouflage for residual discoloration",
        "Counseling for psychological impact of facial birthmark",
    ]),
]

for i, (col_title, color, bullets) in enumerate(treatment_cols):
    x = 0.3 + i * 4.35
    add_rect(slide, x, 1.25, 4.1, 5.95, C_WHITE)
    add_rect(slide, x, 1.25, 4.1, 0.6, color)
    add_text(slide, col_title, x + 0.1, 1.25, 3.9, 0.6,
             size=12, bold=True, color=C_WHITE, align=PP_ALIGN.CENTER, v_anchor=MSO_ANCHOR.MIDDLE)
    tb = slide.shapes.add_textbox(Inches(x + 0.1), Inches(1.95), Inches(3.85), Inches(5.2))
    tf = tb.text_frame; tf.word_wrap = True
    for txt in bullets:
        add_bullet_para(tf, txt, size=11.5, color=C_TEXT, space_before=3)


# ═══════════════════════════════════════════════════════════════
# SLIDE 7 — PROGNOSIS & SUMMARY
# ═══════════════════════════════════════════════════════════════
slide = prs.slides.add_slide(blank)
set_bg(slide, C_LIGHT_GREY)
section_header_bar(slide, "Prognosis & Summary", C_DARK_BLUE)
accent_bar(slide, color=C_ORANGE)

# Prognosis box left
add_rect(slide, 0.35, 1.3, 6.0, 5.85, C_WHITE)
add_rect(slide, 0.35, 1.3, 6.0, 0.45, C_DARK_BLUE)
add_text(slide, "Prognosis", 0.5, 1.3, 5.8, 0.45,
         size=15, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)
tb = slide.shapes.add_textbox(Inches(0.5), Inches(1.85), Inches(5.7), Inches(5.1))
tf = tb.text_frame; tf.word_wrap = True
for txt in [
    "Variable — depends on severity of neurological involvement",
    "Good seizure control + near-normal cognition → normal lifespan and function",
    "Intractable epilepsy + severe intellectual disability → shorter life expectancy but can live into adulthood",
    "Early onset seizures (<6 months) → risk of long-lasting or permanent deficits",
    "Regular ophthalmologic follow-up lifelong — glaucoma can develop at any age",
    "Brain involvement does not occur unless upper face/periorbital PWS is present",
    "No cure; management focuses on symptom control and quality of life",
    "Sirolimus and emerging targeted therapies offer potential future disease modification",
]:
    add_bullet_para(tf, txt, size=12, color=C_TEXT, space_before=4)

# Key points box right
add_rect(slide, 6.8, 1.3, 6.1, 5.85, C_WHITE)
add_rect(slide, 6.8, 1.3, 6.1, 0.45, C_ORANGE)
add_text(slide, "Key Takeaways", 6.9, 1.3, 5.9, 0.45,
         size=15, bold=True, color=C_WHITE, v_anchor=MSO_ANCHOR.MIDDLE)
tb2 = slide.shapes.add_textbox(Inches(6.9), Inches(1.85), Inches(5.8), Inches(5.1))
tf2 = tb2.text_frame; tf2.word_wrap = True
for txt in [
    "SWS = sporadic somatic GNAQ mutation (chr 9q21) — NOT hereditary",
    "Classic triad: Port-wine stain + Leptomeningeal angioma + Glaucoma",
    "Only 15% of upper facial PWS → brain involvement",
    "'Tram-track' calcification on CT is pathognomonic (but may be absent in infants)",
    "MRI with contrast is the imaging modality of choice",
    "Epilepsy management is the cornerstone of neurological treatment",
    "Pulsed-dye laser is first-line for port-wine stain",
    "Early and regular ophthalmologic screening is mandatory",
    "Roach classification: Type I (full), II (skin+eye), III (brain only)",
]:
    add_bullet_para(tf2, txt, size=12, color=C_TEXT, space_before=4)


# ─────────────────────────────────────────
# SAVE
# ─────────────────────────────────────────
out_path = "/tmp/workspace/sturge-weber-ppt/Sturge_Weber_Syndrome.pptx"
buf = BytesIO()
prs.save(buf)
with open(out_path, "wb") as f:
    f.write(buf.getvalue())

print(f"Saved: {out_path}")
print(f"Slides: {len(prs.slides)}")