We present a case series of patients presenting to the Emergency Department of Svp Hospital Ahmedabad with confirmed or suspected beta blocker poisoning over a 12-month period. Patients presented with varying degrees of bradycardia (heart rate 28-48 bpm), hypotension (systolic BP 60-80 mmHg), altered sensorium, and respiratory distress. The most common offending agents were atenolol and amlodipine, with ingestion occurring predominantly in the context of deliberate self-harm. On arrival, 12-lead ECG findings included sinus bradycardia, prolonged PR interval, wide QRS complex, and in severe cases, junctional rhythm and complete heart block. Point-of-care blood glucose revealed hypoglycemia in 40% of cases - a hallmark of non-selective beta blocker toxicity. Activated charcoal was administered to patients presenting within 1-2 hours of ingestion. All patients received high-dose intravenous atropine; those unresponsive were escalated to IV glucagon (5-10 mg bolus, followed by infusion) as first-line antidotal therapy. High-dose insulin euglycemia therapy (HIET) with regular insulin at 1 unit/kg/hour along with glucose infusion was initiated in hemodynamically unstable cases. Intravenous lipid emulsion therapy was used as rescue therapy in refractory toxicity. Temporary cardiac pacing was required in two patients with complete AV block unresponsive to pharmacological measures. Complete hemodynamic recovery was achieved in all surviving patients within 24-72 hours with no long-term cardiac sequelae.