Brachial plexus

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Here is a thorough overview of the Brachial Plexus based on Gray's Anatomy for Students and Miller's Review of Orthopaedics.

Brachial Plexus

Overview

The brachial plexus is a somatic nerve plexus formed by the anterior rami of C5 to C8 and most of T1. It originates in the neck, passes laterally and inferiorly over rib I, and enters the axilla. All major nerves innervating the upper limb originate from it.
- Gray's Anatomy for Students, p. 858

Structure: Roots → Trunks → Divisions → Cords → Branches

The classic mnemonic is "Robert Taylor Drinks Cold Beer" (Roots, Trunks, Divisions, Cords, Branches).
Brachial plexus - major components in the neck and axilla showing roots (C5-T1), trunks, divisions, and cords with their relationship to the anterior and middle scalene muscles and the sympathetic chain.

1. Roots (Anterior Rami)

RootContribution
C5Superior trunk (with C6)
C6Superior trunk (with C5)
C7Middle trunk (alone)
C8Inferior trunk (with T1)
T1Inferior trunk (with C8)
  • Roots lie between anterior and middle scalene muscles, behind the subclavian artery.
  • Each root receives gray rami communicantes from the sympathetic trunk, carrying postganglionic sympathetic fibers.
Branches from roots:
  • Dorsal scapular nerve (C5) - rhomboid major and minor
  • Long thoracic nerve (C5, C6, C7) - serratus anterior
  • Small contribution to the phrenic nerve (C5)

2. Trunks

TrunkFormed ByPosition
SuperiorC5 + C6Superior
MiddleC7 aloneMiddle
InferiorC8 + T1Lies on rib I, posterior to subclavian artery
Branches from trunks (only from the superior trunk):
  • Suprascapular nerve (C5, C6) - supraspinatus and infraspinatus
  • Nerve to subclavius (C5, C6) - subclavius muscle

3. Divisions

Each trunk divides into an anterior and posterior division:
  • Anterior divisions → eventually supply the flexor (anterior) compartments
  • Posterior divisions → eventually supply the extensor (posterior) compartments
  • No peripheral nerves arise directly from divisions.

4. Cords (named by relation to the 2nd part of the axillary artery)

CordOriginRootsPosition
LateralAnterior divisions of superior + middle trunksC5-C7Lateral to axillary artery
MedialAnterior division of inferior trunkC8-T1Medial to axillary artery
PosteriorAll three posterior divisionsC5-T1Posterior to axillary artery

5. Terminal Branches

Complete schematic of brachial plexus showing all branches from roots to terminal nerves, plus anatomical relationships to the axillary artery.
From the Lateral Cord:
  • Lateral pectoral nerve - pectoralis major
  • Musculocutaneous nerve (C5-C7) - coracobrachialis, biceps, brachialis; becomes lateral cutaneous nerve of forearm
  • Lateral root of the median nerve
From the Medial Cord:
  • Medial pectoral nerve - pectoralis minor (and minor)
  • Medial cutaneous nerve of the arm
  • Medial cutaneous nerve of the forearm
  • Ulnar nerve (C8-T1)
  • Medial root of the median nerve
From the Posterior Cord:
  • Upper subscapular nerve - subscapularis
  • Thoracodorsal nerve - latissimus dorsi
  • Lower subscapular nerve - subscapularis and teres major
  • Axillary nerve (C5-C6) - deltoid and teres minor
  • Radial nerve (C5-T1) - all posterior compartment muscles of arm and forearm
Note: The median nerve (C5-T1) is formed from contributions of both the lateral and medial cords.

Clinical Injuries

Supraclavicular vs. Infraclavicular Lesions

Brachial plexus injuries are classified as preganglionic (avulsion) or postganglionic. Preganglionic injuries have the worst prognosis because the cell body is intact but the nerve root is avulsed from the spinal cord.
Clues to preganglionic injury:
  • Horner syndrome (ptosis, miosis, anhidrosis) - sympathetic chain involvement
  • Winged scapula - long thoracic nerve involvement
  • Weak rhomboids - dorsal scapular nerve involvement
  • Normal sensory nerve action potentials (SNAPs) despite sensory loss on exam (cell bodies in dorsal root ganglia are intact)
  • EMG: denervation of paraspinal muscles
  • Elevated hemidiaphragm (phrenic nerve involvement)
- Miller's Review of Orthopaedics, p. 697-698

Common Injury Patterns

PatternRootsMechanismClassic Deficit
Erb's palsy (upper trunk)C5-C6Downward traction on shoulder; obstetric"Waiter's tip" - arm adducted, IR, elbow extended, forearm pronated
Klumpke's palsy (lower trunk)C8-T1Upward traction on armIntrinsic hand muscles, + Horner if T1 root avulsed
Burners/StingersUpper plexusFootball - compression at Erb's pointTransient burning pain, unilateral only
Obstetric brachial plexopathyVariableShoulder dystocia, forceps deliveryVariable; high birth weight risk factor

Investigations

  • CT myelography - detects nerve root avulsions (pseudomeningoceles)
  • MRI - peripheral neuroma, mass lesions
  • EMG/NCS - extent of denervation; must be done 4-6 weeks post-injury (Wallerian degeneration)
  • SNAPs - normal in preganglionic lesions despite clinical sensory loss
  • Chest X-ray (inspiratory + expiratory) - elevated hemidiaphragm = phrenic nerve involvement
  • Cervical spine X-ray: transverse process fracture suggests root avulsion

Treatment

TimingIndication
ImmediatePenetrating trauma, iatrogenic injury, vascular injury, progressive deficits
3-12 weeksIncomplete/near-complete injury from high-energy mechanism
3-6 monthsIncomplete upper plexus lesion from low-energy; plateau in recovery
>6 monthsLess predictable; muscle fibrosis begins at 18-24 months
Key surgical options:
  • Neuroma excision + cable grafting (sural nerve, medial brachial/antebrachial cutaneous nerves as donors)
  • Nerve transfers when insufficient proximal axons (avulsions):
    • Oberlin transfer: ulnar nerve fascicle to FCU → musculocutaneous nerve (restores elbow flexion)
    • Spinal accessory (CN XI) → suprascapular nerve (shoulder abduction)
    • Triceps branch of radial nerve → axillary nerve (Leechavengvong procedure)
  • Priorities: elbow flexion > shoulder stabilization > hand function
  • Best results in young patients treated within 3 months
- Miller's Review of Orthopaedics, pp. 697-699

Obstetric Brachial Plexopathy (neonatal)

  • Risk factors: high birth weight, cephalopelvic disproportion, shoulder dystocia, forceps delivery
  • Good prognosis: biceps + deltoid = M1 by 2 months → complete recovery possible
  • Poor prognosis: no biceps contraction by 3-6 months
  • Nerve grafting results are better in infants than adults; hand intrinsic reinnervation is possible

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Here is a complete, exam-focused anatomy of the brachial plexus - roots to terminal branches.

Brachial Plexus - Full Anatomy (Exam Prep)

The Big Picture

The brachial plexus forms from anterior rami of C5-T1, originates between the anterior and middle scalene muscles in the neck, crosses rib I, and enters the axilla to supply the entire upper limb.
Mnemonic for structure: Robert Taylor Drinks Cold Beer = Roots, Trunks, Divisions, Cords, Branches

Complete Schematic

Complete brachial plexus schematic showing C5-T1 roots, three trunks, six divisions, three cords, and all terminal branches including their relationships to one another.

Step 1: Roots (Anterior Rami)

The roots lie between the anterior scalene and middle scalene muscles, posterior to the subclavian artery. They receive gray rami communicantes from the sympathetic trunk.
RootJoins to Form
C5 + C6Superior (upper) trunk
C7Middle trunk (alone)
C8 + T1Inferior (lower) trunk
Branches off the roots (pre-trunk):
NerveRoot OriginMuscle SuppliedExam Clue
Dorsal scapular nerveC5Rhomboid major + minor, levator scapulaeMedial scapular winging
Long thoracic nerveC5, C6, C7Serratus anteriorLateral/anterior scapular winging ("wings" on push-up)
Contribution to phrenicC5 (small)DiaphragmElevated hemidiaphragm = root avulsion clue
Mnemonic for long thoracic: C5, 6, 7 keep the wing off heaven (serratus anterior keeps scapula flat)

Step 2: Trunks

Trunks cross the posterior triangle of the neck and the base of rib I.
Branches off the trunks (only from the superior trunk):
NerveRootSuppliesLesion
Suprascapular nerveC5, C6Supraspinatus + infraspinatusPasses through suprascapular foramen; ganglion here causes isolated infraspinatus/supraspinatus wasting
Nerve to subclaviusC5, C6SubclaviusRarely clinically significant

Step 3: Divisions

Each trunk splits into an anterior and a posterior division - 6 divisions total. No branches arise from divisions. This is the crossroads that separates flexor-supply from extensor-supply.
  • Anterior divisions → Lateral + Medial cords (supply flexor/anterior compartments)
  • Posterior divisions → Posterior cord (supply extensor/posterior compartments)

Step 4: Cords (named by position relative to the 2nd part of the axillary artery)

CordFormed FromRootsPosition
LateralAnt. div. superior + middle trunksC5-C7Lateral to axillary artery
MedialAnt. div. inferior trunkC8-T1Medial to axillary artery
PosteriorAll 3 posterior divisionsC5-T1Posterior to axillary artery

Step 5: Branches (Terminal + Collateral)

From the Lateral Cord (C5-C7)

BranchRoot ValuesMotor SupplySensory Supply
Lateral pectoral nerveC5-C7Pectoralis major (primarily)None
Musculocutaneous nerveC5-C7Coracobrachialis, biceps brachii, brachialisLateral forearm (as lateral cutaneous nerve of forearm)
Lateral root of median nerveC5-C7- contributes to median nerve --
The musculocutaneous nerve pierces coracobrachialis, runs between biceps and brachialis, and becomes the lateral cutaneous nerve of the forearm. Loss = weak elbow flexion + supination; sensory loss over lateral forearm.

From the Medial Cord (C8-T1)

BranchRoot ValuesMotor SupplySensory Supply
Medial pectoral nerveC8-T1Pectoralis minor + majorNone
Medial cutaneous nerve of armC8-T1NoneMedial arm (lower 1/3)
Medial cutaneous nerve of forearmC8-T1NoneMedial forearm to wrist
Ulnar nerveC8-T1FCU, medial FDP, all intrinsics except 3 thenar + 2 lateral lumbricalsLittle finger, medial ring finger (palm + dorsum)
Medial root of median nerveC8-T1- contributes to median nerve --

From the Posterior Cord (C5-T1)

Posterior cord branches in the axilla: superior subscapular nerve, thoracodorsal nerve, inferior subscapular nerve, axillary nerve, and radial nerve.
BranchRoot ValuesMotor SupplyExam Clue
Superior subscapular nerveC5-C6Subscapularis (upper)-
Thoracodorsal nerveC6-C8Latissimus dorsi"Cough impulse" test for lat dorsi
Inferior subscapular nerveC5-C6Subscapularis (lower) + teres major-
Axillary nerveC5-C6Deltoid + teres minor; cutaneous over "regimental badge" areaExits via quadrangular space; damaged in shoulder dislocation or surgical neck #
Radial nerveC5-T1ALL posterior arm + forearm muscles (triceps, brachioradialis, ECRL, ECRB, supinator, extensors)Exits via triangular interval with profunda brachii; wrist drop with mid-shaft humerus #

The Median Nerve - Special Case

The median nerve (C5-T1) is unique - it is formed by contributions from both the lateral cord (C5-C7) and medial cord (C8-T1), uniting anterior to the third part of the axillary artery. It supplies:
  • Motor: All anterior forearm muscles except FCU and medial FDP; thenar muscles (LOAF - lateral 2 lumbricals, Opponens pollicis, Abductor pollicis brevis, Flexor pollicis brevis)
  • Sensory: Lateral 3.5 fingers on palm side; lateral palm

Quick Cord-to-Branch Summary Table

CordBranchesMemory Aid
LateralLateral pectoral, Musculocutaneous, Lateral root median"LML"
MedialMedial pectoral, Med. cut. arm, Med. cut. forearm, Ulnar, Medial root median"My Aunt Mabel Ulcerates"
PosteriorUpper subscapular, Thoracodorsal, Lower subscapular, Axillary, Radial"STAR" = Subscapular (×2), Thoracodorsal, Axillary, Radial

Injury Level - What to Expect

Level InjuredCommon CauseKey Deficit
Roots (preganglionic avulsion)High-energy motorcycle crashHorner's syndrome, winged scapula, normal SNAPs but no sensation
Superior trunk (C5-C6) - Erb'sTraction on neck/shoulder; obstetric"Waiter's tip" - arm IR, adducted, elbow extended, forearm pronated. Weak deltoid, biceps, brachioradialis
Inferior trunk (C8-T1) - Klumpke'sUpward arm traction; Pancoast tumourIntrinsic hand weakness; claw hand; Horner's if T1 root avulsed
Posterior cordAnterior shoulder dislocationAxillary + radial nerve palsy - deltoid weakness + wrist drop
Lateral cordClavicle #Musculocutaneous + lateral median root loss

Key "In the Clinic" Points for Exams

  • Cervical spine injuries affect roots
  • First rib fracture/severe trauma affects trunks
  • Glenohumeral joint dislocation affects divisions and cords
  • Axillary nerve is the most commonly injured nerve with anterior shoulder dislocation (tests: sensation over regimental badge area and deltoid power)
  • Radial nerve is at risk at the spiral groove of the humerus (mid-shaft fracture = wrist drop)
  • Ulnar nerve is at risk at the medial epicondyle (cubital tunnel)
  • Median nerve is at risk in the carpal tunnel (CTS) - most common entrapment neuropathy
Sources: Gray's Anatomy for Students, pp. 858-867; Miller's Review of Orthopaedics, pp. 697-699
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