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ECG finding

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Based on careful analysis of the ECG image and the textbook material, here is a comprehensive interpretation:

ECG Findings — Interpretation

Patient: Female, 60 years old | HR: 90 bpm | Speed: 25 mm/sec | Gain: 10 mm/mV

Primary Finding: Left Ventricular Hypertrophy (LVH) with Strain Pattern

Rhythm & Rate

  • Sinus rhythm, rate ~90 bpm — regular

Voltage Criteria for LVH

  • Deep S waves in right precordial leads (V1–V2) combined with tall R waves in left precordial leads (V4–V6)
  • The Sokolow-Lyon criterion: SV₁ + RV₅ or RV₆ >35 mm — appears met on this tracing

Repolarization / Strain Pattern

  • ST-segment depression with asymmetric T-wave inversion in leads I, aVL, and the lateral precordial leads (V4–V6) — this is the classic LV "strain" pattern, reflecting repolarization abnormality in the hypertrophied myocardium

Axis

  • QRS axis appears normal to mildly leftward (~0° to –30°), consistent with LVH

P waves

  • Broad/notched P waves in inferior leads suggest possible left atrial abnormality (enlargement) — this further increases confidence in LVH diagnosis

Differential / Additional Considerations

FeatureSignificance
LV strain patternChronic pressure/volume overload (hypertension, aortic stenosis, HCM)
Left atrial enlargementOften co-exists with LVH due to elevated LV end-diastolic pressure
No pathological Q wavesNo evidence of prior MI
No bundle branch blockQRS appears <120 ms

Likely Underlying Etiologies

  1. Systemic hypertension — most common cause of LVH, especially in a 60-year-old female
  2. Aortic stenosis — pressure overload LVH
  3. Hypertrophic cardiomyopathy (HCM) — if asymmetric

Reference Diagram (Harrison's, Fig. 247-9)

LVH vs RVH ECG pattern diagram showing QRS changes in V1 and V6
LVH increases electrical forces directed left and posteriorly, with repolarization abnormalities causing ST depression and T-wave inversion in leads with prominent R waves — Harrison's Principles of Internal Medicine, 22E

Recommended Next Steps

  • Echocardiogram — to confirm LVH, assess wall thickness, LVEF, and diastolic function (more sensitive and specific than ECG)
  • Blood pressure assessment — hypertension workup
  • Clinical correlation with symptoms (dyspnea, chest pain, exertional syncope) to exclude aortic stenosis or HCM
Note: ECG voltage criteria for LVH have low sensitivity (~40–60%) but reasonable specificity. The combination of voltage + strain pattern increases diagnostic confidence. — Harrison's Principles of Internal Medicine, 22E, p. 1914–1915
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